Lidokain pobichni. Ledokain ampoules, instructions on how to get it. Special requests for storing Ledokainu.

Lidocaine is carried out until the IV generation of anesthetics. First buv vikoristaniy yak zealous zasіb in dentistry in 1944 rotsі.

Until now, it is widely practiced in medicine through the high efficiency and high performance.

lidokain in different forms Stay in dentistry for anesthesia and pain. I can anesthetize my dyu. Spriy enlarged sudin without tearing the fabric

Rivnomirno razpodilyaєtsya on a blotted dilyanka stretching a short period of an hour.

Vikoristovuyutsya at the liking of the onset of dental illnesses:

In dentistry, it is important to vickorize in ampoules. In other forms, it can be used for toothache in the home mind.

Warehouse and medication delivery

Rozchin in ampoules is less effective. Before the warehouse 2% - the drug is included:

On vidminu vid novokain Danium drug good dіє in fired fabrics. Not maє negative infusion on the heart-vascular system. Become low in price. The dosage of the drug is due to the foldability of the patient and the individual tolerance of the patient.

Lidokain in ampoules is dispensed in low percentage rates. Zvvychay vikorystovutsya 2% -lidocain. When carrying out microanesthesia, 1% -schin should be given, the dose of which does not change is 4 ml.

In case of overdosed lips, there may be headaches and weakness. Feeling like it is not easy for supervisees to get screwed up. The hour of zeniebolyuvannya is trivial from pivgodini to pivtori godini.

Lidokain in carpols, big vidomy, yak "Xilonor" Those who have lost the anesthetic dosage of volodya 3% -rozchin to the drug. Karpool is the best shape for a vipusku. Disposable sealed containers do not compromise on insulated ampoules, or the robot lays down with the preparation.

The drug "Ksilonor" is dispensed with a volume of 1.7 ml. Before the warehouse of the anesthetic, there should be a subo-sound supplement, which can be used to supplement the drug and make it more effective for pain.

Mechanism of diya and perevagi to the drug

The amount of lidocaine in ampoules grows to be highly effective, reaching up to 95%. Viyavlyak antiarrhythmic action. Block natrіevі channels of neurons. The maximum effect of the introduction is delayed after 40-60 seconds.

Metabolize in ovens, vivoditsya with a cross.

Sered perevag drug - visoka bioavailability. The drug is highly effective and volodya great shvidkistyu vmoktuvannya. There is a low level of efficiency in the management of anesthetic drugs alone because of those required in current medical conditions.

In the middle of a shortage of a drug - a side effects and the non-triviality of the action, which is important when carrying out trivial operations.

Features of suction spray

Lidocaine in a spray (aerosol) vikoristovuyutsya for local anesthesia. Become a high concentration of active speech. Before the warehouse, the preparation also contains ethyl alcohol and m'yat oil. The peak of concentration is infused in a year and up to 7-8 years.

Shown until dry lidocaine in the form of aerosol є stomatologic diseases, Including children, seeing dental calculus, installing crowns, operations on tissues mouthwash.

10% - a warehouse with a high concentration, protects the effectiveness of the drug when it is squeezed. In addition, it is recommended to re-conduct the sickness to achieve the maximum effect.

When obrobtsi mouth emptying in children, put the warehouse on a cotton swab. The dosage of the drug should be deposited from the size of the blasted surface and the folding of the dental treatment.

Vikoristannya Geliv

Anesthetic dental gels are used to relieve pain in case of ruptured teeth and dental problems. We offer such gels based on Ledokoin:

If you choose a first-aid kit for a baby before rock, then the video will be good for you.

It means that ointment with Kidokin in dentistry is not vicious, so the ointment form is ineffective on mucous membranes of empty mouth.

Price for special form vipusku

Fallingly from the form of the release of the price of the

1. Rozchin in ampoulesє the found drug with the help of active speech. It is based on concentration, the price for the drug is from 12 to 60 rubles.
2. part of the drug in carpules- Ksilonor to become close to 50 rubles. for the carpula.
3. Price for medication in aerosol form koliva to be in between 300-400 rubles.
4. dental gels cost from 250 to 500 rubles.

Stagnation for children and children

Lidocaine in ampoules and carpules with vaginosis does not get stagnant. For children of a young age and lidocaine in the form of a spray, which can be used for muscle anesthesia during dental treatment.

In case of lactation, drugs based on speech, directly from the form, are not recommended.

The prototype is shown before the end of the day

Lydocainous anesthetics are contraindicated for:

The main shortcoming of the drug is the risk of a great number of side effects, middle ones:

• zamorochennya, tediousness, weakness, loss of evidence and іnshі roslady from the side of the central nervous system;
• tachycardia, decrease arterial vise and іnshі troubles in robotі heart-vascular system;
• pickling, blotting;
• allergic reactions.

Gross formula

Pharmacological group of speech Lidocaine

Nosological classification (ICD-10)

CAS code

Characteristics of speech Lidocaine

Bili, or mayzhe bili, crystalline powder, rotten in water. Vikoristovuєtsya in the viglyadі hydrochloric acid salt, easy to pick up in the water.

pharmacology

Antiarrhythmic activity is explained by the attitudes of phase 4 (diastolic depolarization) in Purkin fibers, changes in automatism, and attitudes of ectopic vognisches of restlessness. On the speed of the shvidkoy depolarization (phase 0) is not infused, but slightly lower. Increased penetration of membranes for ionizing calories, accelerating the process of repolarization and shortening the potential of the action. No change in sinus-atrial node wakefulness, little infusion on myocardial performance and speed. With the on / in the introduced di shvidko and shortly (10-20 min).

Mechanism of the micro-anesthetic effect of the polarization in the stabilization of the neuronal membrane, a decrease in penetration for sodium ions, as a result of the reduction in the potential of the action and the conduct of the pulses. Mossy antagonism with calcium ions. Shvidko gidrolizuєtsya in a slightly alkaline middle tissue and for a short latent period for 60-90 min. When heated (tissue acidosis), anesthetic activity decreases. Effective for all types of mussel zenbolyuvannya. Rozshiryuє sudini. Chi does not appear teasing on the fabric.

With i / v introduced C max, it is practically “on the head” (after 45-90 s), with i / m - after 5-15 minutes. To reach quickly absorbed from the mucous membrane of the upper dikhalnyh nobles or empty company (C max reach after 10-20 min). After receiving the medication, the bioavailability becomes 15-35%, as well as 70% for the drug, which gets wet when it is "first passed" through the oven. Plasma has 50-80% clinks with whites. Stable concentration in the blood rises in 3-4 years with uninterrupted intravenous injection (in patients with myocardial infarction - after 8-10 hours). The therapeutic effect develops at a concentration of 1.5-5 μg / ml. It is easy to pass through the gistogematic bar'єri, including the hematoencephalic bar'єr. A handful of good blood supplying tissues (heart, legends, brain, liver, spleen), sometimes - in fat and m'yazu fabric... Penetrating through the placenta, 40-55% of the concentration of the breed appears in the organisms of the newborn. Milk is excreted in the breast. T 1/2 for intravenous bolus injection - 1.5-2 hours (in newborns - 3 hours), with trivial intravenous infusions - up to 3 years or more. If the function of the T 1/2 furnace is damaged, it can be increased 2 times or more. Shvidko and the higher the rate of metabolism in the oven (less than 10% in the unconfined view of the cross section). The main path of degradation is the oxide N-disalkyluvannya, at which active metabolism (monoethylglіtsіnksіlіdіn і glіtsіnksіlіdіn) is established, which may be T 1/2 2 h і 10 h for a period of time. with chronic nirkova lack Possibility of cumulation of metabolites. The triviality of the diy - 10-20 min with intravenous injection and 60-90 min - with intravenous injection.

In case of mice's stasis on non-shkodzhenu shkiru (at the viglyadі plates), the vine has a therapeutic effect, sufficient for the nobility of pain syndrome, without developing a systemic effect.

Stuck in speech Lidocaine

Shlunochkov_extrasystoles and tachyarrhythmias, incl. with gostromy myocardial infarction, in during the operational period, Fibrillation of shlunochkiv; all types of medical anesthesia, incl. surface, infiltration, providnikova, epidural, spinal, intraligamentary at promptly, Sick manners, endoscopic and instrumental reading; at the viewer plates - pain syndrome with vertebral lesions, myositis, postherpetic neuralgia.

Prototype

Hypersensitivity, presence in anamnesis of epileptiforms in court for lidocaine, WPW syndrome, cardiogenic shock, weakness of the sinus node, heart block (AV, intraventricular, sinus-atrium), important, liver disease.

Crimped to sucking

Becomes supervised by decreased hepatic blood flow (for example, with chronic heart failure, liver disease), progressing heart and heart failure (inevitably due to the development of heart blockade and shock), weakening abduction vik(Older than 65 years), the deterioration of the integrity of the small curves (in the case of an overlay plate), the vagina, the age of the breast.

Stagnation during vaginosis and breastfeeding

When vaginosti and when the breast is younger, as well as cleansing, the effect of therapy transforms the potential rizik for the fetus and the baby.

Lidocaine

On the side of the nervous system that organs are sensitive: impulse, or nervousness of the central nervous system, nervousness, euphoria, blinking "fly" in front of ochima, fear of fear, drowsiness, head b_l, Zapamorochennya, noise in wuhah, diplopia, deterioration of testimony, attrition, or misdirection, misery, tremor, disorientation, sudomi

On the side of the cardiovascular system and blood (blood formation, hemostasis): sinus bradycardia, broken heart conduction, transverse heart block, decreased arterial vise, collapse.

On the side of the organs in the intestinal tract: nudity of blues.

Allergic reactions: generalization of exfoliative dermatitis, anaphylactic shock, angioedema in the area, contact dermatitis

Інші: in the face of heat, cold, or some of them, evil hyperthermia, driving immune system.

vzaєmodiya

Beta-adrenergic blockers increase the development of bradycardia and hypotension. Norepinephrine and beta-adrenergic blockers, which reduce liver blood flow, decrease (increase in toxicity), isoprenaline and glucagon - increase the clearing of lidocaine. Cimetidine increases its concentration in the plasma (vitisnyaє zi link with the bottles and the positive activation in the ovens). Barbiturati, victories in the induction of enzymes, stimulate the degradation of lidocaine and reduce its activity. Protysomes (lost guides) accelerate the biological transformation in the liver (the concentration in the blood changes), with intravenous administration it is possible to improve the cardiodepressive activity of the lady. Antіarіtmіki (amiodarone, verapamil, hіnіdin, aymalin) potential for cardiodepression. By the end of the day, we can celebrate the central nervous system and hallucinations. Pidsilyu dіyu dіyu anesthesia (hexobarbіtal, thіopental sodium) and sodіnіvnu to the dyshalal center, weakened cardiotonic infusion of digitoxin, loosen muscle relaxation (clicks with parasitic drugs) Іngіbіtori MAO prolong mіscevu anesthesia.

Overdose

symptoms: psychomotor zabuchennya, zapamorochennya, backward weakness, decreased arterial pressure, tremor, tonic-clonic sudomi, coma, collapse, AV blockade, driving the central nervous system, zupinka dyhannya.

lykuvannya: fixation of admission, legeneva ventilation, oxygen therapy, prototyping, vasoconstriction (noradrenaline, mezaton), with bradycardia - holinolytics (atropin). It is possible to carry out intubation, SHVL, reanimation visits. Dializ is ineffective.

introduction

In / in, in / m, missevo (in viglyadі aerosol, gel, spray, plates).

Zapobіzhni come in speeches Lidocaine

There is a trace of care in case of liver disease and nirok, hypovolemia, severe heart failure due to impaired quickness, genetic schism to malignant hyperthermia. Children who are weakened by ailments, children who have been abducted, need a dose correction according to their physical status. When introduced into vascularized tissue, it is recommended to conduct an aspirate test.

In case of muscular stasis with protection of vikoristovy in case of infection or injury in the mice of stasis.

Even during the period when the plate was stored, it was not seen as a matter of fact; Vikoristani plates are not guilty but are available for children or homemade things. Immediately writing the plate of the plate.

special requests

For anesthetic supplementation, 1 drop of 0.1% can be added to the dose of adrenaline per 5-10 ml of lidocaine (at the same time, the maximum allowable dose is increased to 500 mg).

Vzamodії with іnshih dyuchy speeches

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