Sanitary microbiology. Fundamentals of ecological microbiology microflora for healthy people

understanding microbiocenosis

Normal microflora suprovodzhuє his ruler by holding out his life. About the sutta of the meaning in the pedagogy of life, the organism is to be guarded by the creatures-gnotobiontams (by removing the power microflori), the life of those who are quite often seen as normal in such a way. Into the ring of tsim vchenya about the normal microflora of people and destructions is itself to complete the hundredth part of medical microbiology.

In this hour, we will firmly establish є the provisions about those that the organism of people and how they inhabit their microorganisms - the whole ecosystem.

Happy positions, normal microflora look yak the absence of microbiocenoses, are characterized by a singular species warehouse and occupy the same biotype in the body. In be-yaku microbiocenosis slid development:

  • Indigenic, autochthonous flora is characteristic, which is constantly being developed to see microorganisms. Їх number is altogether small, but numerically, the stench is most clearly presented;
  • Alochthonous flora - transient, supplementary and vipadkov. Species warehouse of such microorganisms is versatile, ale the stench is unnumbered.

The upper hives and mucous membranes of humans are clearly populated with bacteria. With a large number of bacteria that inhabit the fabrics (shkiru, mucous membranes), in a large number of times, the number of the sovereign's vlast cells has been exceeded. The number of bacteria in the biocenosis can be upsetting for some bacteria in the order of the order, and it is not the least of them to keep within the accepted standards. formed microbiocenosisіsnu yak dine tsіle. like the spirits of the common food lancers and the crocheted microecology of the species.

The number of microbial biocenoses, which can be seen in the body of healthy people, become normal microflora of people.

In Danish hour, a normal microflora looks like an independent extracorporeal organ. Vin maє is characteristic Anatomy Budova- biodiesel, іth tackled singing functions.

It has been established that the microflora is normal to reach a high species and individual specificity and stability.

Features of normal microfloria

Normal microflora of okremich biotopes Rizna, ale, to order a number of basic laws:

  • to finish it is stable;
  • approve the biodiesel;
  • is represented by a number of species, the middle of which are dominant and vid-napovnyuvachi;
  • transferable є anaerobic bacteria.

Normal microflora is characterized by anatomical features - the skin is ecologic and has its own species warehouse.

Deyakі biotopi are stable at their warehouse, and іnshі (transitory microflora) is gradually changing in the fallowness of the most important factors.

Microorganisms, warehouses normal microflora, are manifested in a clear morphological structure - biofuel, the thickness of which varies from 0.1 to 0.5 mm.

bioplivka It is a polysaccharide framework, which is stored from microbial polysaccharides and mucin, which is a product of cellini to macroorganism. In a whole frame of immobilized microcolonies of bacteria - representatives of normal microflora, which can grow into a decal ball.

To the warehouse normal microflori enter both anaerobic and aerobic bacteria, the ratio of which in a large number of biocenoses becomes 10: 1-100: 1.

The settlement of bacteriums in the rural areas is to be resigned at the moment of the people's life and to continue with the stretching of their life.

Formation of a normal microflora warehouse is regulated by folding antagonistic and synergistic single units and representatives in the biocenoses warehouse.

Warehouse for transit microflori can change in fallowness:

  • vіd vіku;
  • the minds of the last middle-class;
  • minds pratsі, ratsіonu harchuvannya;
  • transferred illnesses;
  • trauma and stress situations.

The warehouse has a normal microflori development:

  • permanently, or a resident microflora, is represented by an admittedly stable warehouse of microorganisms;
  • transient, or for the time microflora, - have spent on the shkіra or mucous shells from the midst of the midst, not getting sick and not being sluggish all the time on the surfaces of people. Vona is represented by saprophytic mentally pathogenic

'Microorganisms, like slugging on skins or mucous membranes, stretching out for decades, days or days. The presence of transient microorganisms is not only due to the hopes of microorganisms from the middle immune system organism of the ruler and warehouse of post-normal microfloria.

The norm is rich in fabrics and organizations of healthy people, as are microorganisms, i.e., E. Steril. To them are admitted:

  • internal organizations;
  • brain and spinal cord;
  • alveoli of legends;
  • internal and mid-air;
  • roof, lymph, spinal cord;
  • uterus, nirki, slaughter and slaughter in the slaughter.

Do not take into account the manifestation of nonspecific clientele and humoral factors Immunity, which transcends the penetration of microbes into the fabric and organisms.

On all large surfaces and on all open spaces, the microflora is shaped to reach the level of microflora, which is specific for a given organ, biotope, or even a dilenca - an epitope. Naybіlsh bagatі microorganisms:

  • Rotova is empty;
  • tovsta gut;
  • upper views of the mental system;
  • zvnіshnі vіddіl sechostat system;
  • shkira, especially a hairy part.

Normal intestinal microorganisms- the whole colony of bacteria, which informs the lower parts of the herbal tract and the surface of the mucous membrane. The stench is needed for the easy digestion of humus (grub breast), for the exchange of words and activation of the mussels for infectious diseases, as well as for toxic products.

Normal intestinal microflora- the whole balance of young microbes in the lower forms of the herbal system, so that both healthy and healthy conditions are necessary for the development of a biochemical, metabolic, and immunological organismic human immune system

  • Zakhisna function. Normal microflora is reduced to pathogenic and mentally pathogenic microorganisms. Brown bacteria overwhelm the colonization of the intestines by those who do not control them, infectious diseases. If there is a decrease in the number of normal microorganisms, repair the increase in potential microorganisms. Ginno-ignition processes are developing, bacterial contamination of blood (septicemia) is observed. Therefore, it is important not to allow a decrease in the number of normal microflorias.
  • Herbal function. The intestinal microflora takes its part in the fermentation of proteins, fats, high molecular weight carbohydrates. Cinnamon bacteria reduce the amount of blood cells and surplus chemus, the necessary level of acidity (pH) is fed into the intestines. Mikroflora inactivu (lusen phosphatase, Enterokinazi), take a part in the approved products in the drop of blood (phenol, indole, skatole) and stimulate peristalsis. Microorganisms of the herbal tract also regulate the metabolism of gum acids. Take the transformation of bilirubin (chewing pigment) into stercobilin and urobilin. Cinnamon bacteria play an important role in cholesterol reworking stages. It’s a coprosterin that doesn’t get wet in your intestines and go into feces. Normal flora is good for reducing liver acid production and control for normal cholesterol levels in the body.
  • Synthetic (metabolic) function. Corinth bacteria of the herbal tract are violated by vitamins (C, K, H, PP, E, group B) and essential amino acids. Kishkova microflora with a shorter development of saline and calcium, that is, the development of such ailments such as anemia and rachitis. For the rakhunok, the cinnamon bacteria are more active in the wetting of vitamins (D 3, B 12 and folic acid), Scho regulate the blood-forming system. Metabolіchna funktsіya kishkovoї mіkroflori takozh proyavlyaєtsya in zdatnostі sintezuvati them antibіotikopodіbnі rechovini (atsidofіlіn, laktotsіdіn, kolіtsіni INSHI i) i bіologіchno aktivnі spoluki (gіstamіn, dimethylamine, i t tiramіn. D.) SSMSC pereshkodzhayut zrostannyu i rozmnozhennyu mіkroorganіzmіv pathogens.
  • Detoxification function. The whole function is associated with the capabilities of the intestinal microflora, the speed of the feeling, the number and the vision of feces unsafe toxic products: salts important metals, Nitrites, mutagens, xenobiotics and іnshі. Shkіdlivі spoluks are not permeated in the tissues of the body. Cinnamon bacteria will prevent toxic injections.
  • Immunity function. The normal flora of the intestine stimulates the synthesis of immunoglobulins - special proteins that stimulate the body or organisms unsafe infections... Likewise, brown bacteria tolerate the system of phagocytic cells (nonspecific immunity), which are built up to the death and destruction of pathogenic microbes (div.).

Representatives of intestinal microflori

All intestinal microflora grows on:

  1. normal (basic);
  2. intellectually pathogenic;
  3. pathogen.

Among all the representatives there are anaerobes and aerobias. The appearance of one kind of one pole in the peculiarities of the moment and the living. Aerobi - a whole host of microorganisms, life and growth only in minds of continuous access. Representatives of the іншої group are divided into 2 types: obligatnі (strict) and optional (іmovnі) anaerobi. First and foremost, provide energy for your own energy when you have access to energy. For regional anaerobes, it is labial, and for facultative ones, it is numb, so that microorganisms can be found in their presence.

normal microorganisms

Before them, gram-positive (bifidobacteria, lactobacteria, eubacteria, peptostreptococci) and gram-negative (bacteroid, fusobacteria, veilonelli) anaerobi are referred to. This name is tied to the nickname of the Danish bacteriologist - Gram. Winning a special method of making smears from aniline barvnik, iodine and alcohol. When microscopic microscopic part of the bacterium can be blue-violet color and is reduced to gram-positive. Іnshі microorganisms zebarvlyuyutsya. For a short visualization of cich bacteria, a contrasting barvnik (fuchsin) is stuck in, which is barbed into a rhubarb coli. Tse gramnegative microorganisms.

All representatives of the group are strict anaerobes. The stench is the basis of all intestinal microflora (92-95%). Corinth Bacteria Vibrate antibiotic-like speech, which additionally helps the vitality of children of non-insecure infections. Also, normal microorganisms create a zone of "acidification" (pH = 4.0-5.0) in the middle of the intestine and set the water on the surface of the mucous membrane. In such a rank, the bar'єr is formed, which is the transition to the colonization of third-party bacteria, which was consumed by the zzovny. Cinnamon microorganisms regulate the balance of intellectually pathogenic flora, which is difficult for the overwhelming growth. Take part in the synthesis of vitamins.

Before them are gram-positive (clostridia, staphylococcus, streptococcus, bacilli) and gram-negative (also - intestinal sticks and representatives of the enterobacteria family: Proteus, Klebsiula, Interobacterium.

Cy microorganisms є mentally pathogenic. Tobto, with good health in the body, it is infused only positively, as in normal microfloria. Influx of unwelcoming factors to produce up to їх overworldly propagation and re-incarnation in ailing animals. To develop from the direєyu, wicked character of the style (from the houses to the slime, blood or pus) and the destruction of the self-esteem. Kilkisny rist of intellectually pathogenic microfloria can be used for dressings with weakening of immunity, fired up herbal system, wrong food and consumption drugs(Antibiotics, hormones, cytostatics, analgesics and others).

The leading representative of enterobacteria is tse z typical biological authorities. Wonderful activation of the synthesis of immunoglobulin. Specific libraries interrelate with pathogenic microorganisms from the family of enterobacteria and transfer them penetrated into the mucus membrane. The key to the production of speech is the amount of antibacterial activity. It is also normal for normal growth and growth of rotten and pathogenic microorganisms from the family of enterobacteria - intestinal sticks with changes in biological tissue power (hemolysis). Yesherichi take part in the synthesis of V.K.

Other fungi of the genus Candida can also be referred to as intellectually pathogenic microflora. The smell is rare in healthy children and grown-ups. Emergence in calories, in a small number of cases, can be supervised by the patient's clerical conditions with the help of a turn-on (oversized growth and proliferation of other fungi). It is especially important for children of a young age and ailments due to a decrease in immunity.

pathogenic microorganisms

Tse bakterії, scho to play in herbal tract zzzovnі i wiklicyut gstrі intestinal infections... Infection with pathogenic microorganisms can be caused by implantation of food products (vegetables, fruits, etc.) and water, with broken rules of special hygiene and contact with ailments. The normal in the intestine does not develop. Before them, pathogenic pathogens of insecure infections, pseudotuberculosis and others, are known. Most of the representatives of the whole group - shigeli, salmoneli, іrsinia and t. D. The stench wicks of serious hospital infections.

All ailing bacteria provoke the development of intestinal inflammation by the type of ablation of the style (diarrhea, in the feces of mucus, shelter, nausea) and development of intoxication to the body. Cinnamon microflora to drive.

Normalize the bacteria in the intestines

Brown bacteria

normal microorganismsChildren older than 1 rockold age
bifidobacteria10 9 –10 10 10 8 –10 10 10 10 –10 11 10 9 –10 10
lactobacilli10 6 –10 7 10 7 –10 8 10 7 –10 8 >10 9
eubacteria10 6 –10 7 >10 10 10 9 –10 10 10 9 –10 10
Pepto-streptococci<10 5 >10 9 10 9 –10 10 10 9 –10 10
bacteroid10 7 –10 8 10 8 –10 9 10 9 –10 10 10 9 –10 10
fusobacterіі<10 6 <10 6 10 8 –10 9 10 8 –10 9
veilonelli<10 5 >10 8 10 5 –10 6 10 5 –10 6

KUO / g - the whole number of colonies is set as one microbial in 1 gram of viporozhnen.

Mind-pathogenic bacteria

Mind-pathogenic microorganismsChildren up to 1 day for breastfeedingChildren up to 1 rock on a piece vigodovvannaChildren older than 1 rockold age
Gut sticks with typical powers10 7 –10 8 10 7 –10 8 10 7 –10 8 10 7 –10 8
clostridia10 5 –10 6 10 7 –10 8 < =10 5 10 6 –10 7
staphylococks10 4 –10 5 10 4 –10 5 <=10 4 10 3 –10 4
streptococci10 6 –10 7 10 8 –10 9 10 7 –10 8 10 7 –10 8
bacilli10 2 –10 3 10 8 –10 9 <10 4 <10 4
Mushroom of the genus Candidaonsutnіonsutnі<10 4 <10 4

Cinnamon intestinal bacteria

Grampositive strict anaerobias:

Gram is strict anaerobi:

  • bacteroid- polymorphic (may change size and shape) sticks. Together with bifidobacteria, they colonize the intestines of newborns up to 6-7 days of life. When breastfeeding, bacteria appear in 50% of children. When a piece of equipment hangs in a large number of types. Bacteria take a part in the pickling and splitting of gum acids.
  • fusobacterіі- polymorphic palichkobnі microorganisms. Characteristic for the intestinal microflora of grown-up people. Frequently hanging from pathological material in case of gross accelerated development of localization. Zdatnі secretuvati leukotoxin (biologic speech with a toxic level of aging to leukocytes) and a factor of platelet aggregation, which is indicative of thromboembolism in case of important septicemia.
  • veilonelli- cocoa microorganisms. For children who are on breastfeeding, there are less than 50% of them. In little ones, on a piece of food, sums hang from a high concentration. Veilonelli is good for gas. With an overwhelming increase in the growth of rice, it can lead to dyspeptic disorders (flatulence, haircuts and diarrhea).

How to reconvert the normal microflora?

Slid to spend bacteriological until the end of the day by sowing on a special living center. Take away the material with a sterile spatula from the rest of the vial. Required obsyag feces - 20 grams. Material for preserving is placed in sterile containers without preservatives. It is necessary to take into account the fact that microorganisms are anaerobics to be guilty of being stolen from the moment of taking feces before sowing. It is recommended to use a special gas mixture (carbon dioxide gas (5%) + water (10%) + nitrogen (85%)), and a lapped crush. From the moment the material is taken, it is guilty to pass no more than 2 years before the ear of bacteriological lingering.

The analysis of feces allows a wide range of microorganisms to be detected, virahuvati and diagnostics are visible rosladi - dysbacteriosis. For destructions in the warehouse of intestinal microflora, a decrease in a part of corny bacteria, an increase in the number of intellectually pathogenic flora due to the wrinkle of normal biological authorities, and also the appearance of ailing animals are characteristic.

Low vm_st normal microflori - how robiti?

Correction of the imbalance of microorganisms is carried out for the additional help of special drugs:

  1. The colonization of the intestine is mainly micro-microflora for the growth of vibrational stimulation of growth and metabolic activity of one or more groups of bacteria. Give preparations not lykarsky zasob. They are not considered to be digested by ingredinti ryzhi, which is a substrate for cinnamon bacteria and does not go through any herbal enzymes. Preparations: "Khilak Forte", "Duphalac" ("Normase"), "Calcium Pantothenate", "Lysozyme" and іnshі.
  2. not live microorganisms, which normalize the balance of intestinal bacteria and compete with mentally pathogenic flora. Beneficially pour on the health of people. Smell to take revenge on cinnamon bifidobacteria, lactobacilli, lactic acid streptococcus, etc. Preparations: "Acylact", "Linex", "Bactisubtil", "Enterol", "Colibacterin", "Lactobacterin" "that іnshi.
  3. Immunostimulating zasobi. Stagnate for the normal microbiocenosis of the intestine and the growth of the organism's forces. Preparations: "KVP", "Immunal", "Exinacea", etc. D.
  4. Likarski zasobi, scho regulate the transit of intestinal space. Wickedness for polishing etching and evacuation. Preparations :, vitamini, etc. D.

Thus, the normal microflora with specific functions - zhisnoy, exchange and immunostimulation - means the microbial ecology of the herbal tract and take part in the growth of the internal middle (home) organism.

Organism of people of settlements (colonization) more than 500 types of microorganisms, which store the normal microorganism of people, which is located in the station (Eubioza) one by one і organism of people. Mikroflora є Stable alcohol production of microorganisms, tobto microbiocenosis. There is a colonization of the surface of the wood and empty, obtained from the navkolishn_m middle. The place of living of the production of microorganisms is called biotope. At normal microorganisms in the lungs and matts. They develop a normal microflora of shkiri, mucous membranes of the company, upper dichloro paths, grass tract and sechostatic system. Among normal microflora there is a resident and transient microflora. The resident (post) regional microflora is represented by microorganisms, permanently present in the organism. Transient (non-functional) microflora is not healthy until it is trivial in the body.

microflora shkiri There is a great deal of significance in the expanded microorganisms in the world. On small and large balls (hairy little balls, through oily and sweaty balls), anaerobes are 3-10 times more, less than aerosols. Shkiru colonize propionibacteria, corinform bacteria, staphylococcus, streptococcus, other Pityrosporum, yeast-like fungi Candida, rare micrococks, Mus. fortuitum. For 1 cm 2 shkіri is brought less than 80,000 microorganisms. The norm does not increase in number as a result of bactericidal sterilizing officials of the school.

At the top of the dick to use sawed particles, nailed by microorganisms, a large part of which will be caught in the nose-and-mouth. Here the growth of bacteria, coriniform bacteria, hemophilic bacilli, peptococci, lactobacilli, staphylococcus, streptococcus, non-pathogenic neuteria and іn. The trachea and bronchi become sterile.

Microflora herbal tractє the most representative for its own warehouse. With a wide range of microorganisms, it is possible to live in an empty grass tract, and also to colonize mucus membranes.

At the empty company bag of actinomycetes, bacterioids, Biphy-tsobacterii, eubacteria, fusobacteria, lactobacteria, hemophilia bacilli, leptotrochias, neuteria, spirochetes, streptococci, staphylococcus, veilonelli. There are also fungi of the genus Candida and most common fungi. Associates of normal microflora and products and living conditions to establish dental plaque.

microflora slunk It is represented by lactobacilli and others, single gram-negative bacteria. Vona kіlka bіdnіshim, nіzh, nіzh, for example, intestines, so yak shlunkovy sіk is low pH value, unpleasant for the life of bagatokh microorganisms. In case of gastritis, vyrazkov_y ales of the shlunk vyavlyayutsya form bacteria - Helicobacter pylori, and ethiological factors of the pathological process.

In the small intestine microorganism in larger, lower in the shlunk; here bifidobacteria, clostridia, eubacteria, lactobacilli, anaerobic coca appear.

Most microorganisms accumulate in tovstiy kishtsi... 1 g of feces contains up to 250 billion microbial cells. Closely 95% of all types of microorganisms are stored anaerobically. The main representatives of intestinal microflora are: gram-positive anaerobic sticks (bifidobacteria, lactobacilli, eubacteria); gram-positive spore-positive anaerobic sticks (clostridia, perfringens and in.); enterococks; gram-negative anaerobic sticks (bacterioids); gram-negative facultative-anaerobic sticks (intestine sticks and similar bacteria with them.

Microflora of the intestine- a free extracorporeal organ. Vona is an antagonist of putreflorous microflora, so as to produce lactic acid, ocetic acid, antibiotics and іn. In general, the role in water-salt metabolism, regulation of the gas storage of the intestine, metabolism of proteins, carbohydrates, fatty acids, cholesterol and nucleic acids, as well as the production of biologically active substances, toxicants, antibiotics, antibiotics morphokinetic role of microflora polyaga in participation in the development of organs and systems of organism; take your part in the physiological firing of the mucous membrane and the change in the diet, over-etching and detoxification of exogenous substrates and metabolites, as well as the function of the liver. The microflora of the vicon is normal, in addition, the anti-mutagenic role, ruinuchi carcinogenic speech.

Pristinkova intestinal microflora I will colonize the mucous membrane of the microcolonies, I will make a kind of biological food, which can be stored from the microbial til and the exopoly-sugar matrix. Exopolisaccharides of microorganisms, called glycocalyx, seize microbial cells from different physical-chemical and biological infusions. The mucous membrane of the intestine can also be found in the intestinal tract.

The important function of normal intestinal microflora, and participation in colonization of colonization resistance, due to the lack of reason, the majority of specific factors in the organism and competitive, antagonistic intestinal features, of the anaerobic intestinal stability

Normal microflora pichvi including bacteria, lactobacilli, peptostreptococci and clostridia.

Representatives of a normal microflora, with a decrease in the opacity of the body, can experience gnarly-igniting processes, so that a normal microflora can become a germ of autoinfection, or an endogenous infection. Vona is also є dzherelom genіv, for example, genіv lіkarskoy stіykostі to antibiotics.

Normal microflora of people - price sukupnist
without microbiocenoses, which are characterized by certain
by our interconnections and by the mice of living.
In the body of people, it seems to the minds of living
to form biotopes with singing microbiocenosis. liu
biy microbiocenosis - the wholeness of microorganisms, there is
a yak on a single tsile, tied with lances
logic.
See normal microflori:
1) resident - permanent, typical for a given species;
2) transient - time-consuming, uncharacteristic for
given to biotope; won’t actively multiply.
Normal microflora is formed from the people. On її for-
muvannya infuse microflora of materi and internal pain
no different middle ground, character.
The factories, which are used to inject normal microflori into the mill.
1. Endogenous:
1) secretory function of the body;
2) hormonal background;
3) acid-tin mill.
2. Exogenous mind life (climatic, pobutov, eco
logical).
Microbial zabrudnennya is typical for all systems, may-
contact with the navkolishn_m middle. In the body of people are
rilnim є roof, liquor, suglobova ridina, spit
ralny ridina, lymph of the thoracic duct, internal organisms:
heart, brain, liver parenchyma, nirok, spleen, uterus, sechovy
mikhur, alveoli of legends.
Normal microflora of the vistila of the mucous membrane in the
de bіoplіvki. Tsei polysaccharide frame is stored from polysacha-
types of microbial cells and mucin. I have a microcolo-
37
vannі kіtin normal microflori. Tovshchina bioplivka -
0.1-0.5 mm. They take place from decilcoh hundreds to decilcoh
thousand microcolonies.
Formation of biofuel for bacteria of the sash before-
woo zahist. In the middle of the bacterium bites, there are more styles to the days
the combination of chemical and physical factors.
Etapi formulating normal microflora of the ventricle
no-intestinal tract (QCT):
1) vipadkovo obsіmenіnnya mucous. In the shlunkov-intestinal tract, treat the lacquer
tobacilli, clostridies, bifidobacteria, micrococks, stafi-
lokokki, enterococci, gut palichka і ін.;
2) the formation of the netting from the striking bacteria on the surface
villi. On nіy fіksuyut in the main palichkopodіbnі
Bacteria, the process of forming the biofuel is constantly going.
The microflora is normal to look at itself
ny extracorporeal organ of the anatomical
structure and functions.
Function of normal microfloria:
1) participation in all types of exchange;
2) detoxification of exo- and endoproducts, trans-
Formation and vision of licars' speeches;
3) participation in the synthesis of vitamins (groups B, E, H, K);
4) zahist:
a) antagonistic (tied to the product bacteriocy-
new);
b) colonization resistance of mucous membranes;
5) immunogenic function.
The most abundant contamination is characterized by:
1) good intestine;
2) empty mouth;
3) sectional system;
4) upper dichalny ways;
5) shkіra.

2. Dysbacteriosis

Dysbacteriosis (dysbiosis) - tse be-like kilkisnі abo
typical changes for a given biotope normal
new mikroflori people, who are the result of the impact
the impact on the macro- or microorganism of the unwelcoming children
chinnik_v.
38
To serve as microbiological indicators of dysbiosis:
1) a decrease in the number of one or more decliners
vid_v;
2) the loss by bacteria of quiet signs or
nya new;
3) an increase in the number of transient types;
4) the emergence of new, non-power of the given biotope of the
dov;
5) weakening of antagonistic activity normal
microflori.
The reasons for the development of dysbacteriosis can be:
1) antibiotic and chemotherapy;
2) important infections;
3) important somatic illnesses;
4) hormone therapy;
5) change the flow;
6) toxic factors;
7) deficiency of vitamins.
Dysbacteriosis of small biotopes maє різні clіnіche-
show it. Intestinal dysbiosis can manifest itself
in viglyadi diarrhea, nonspecific colitis, duodenitis, gastroenteritis
rita, chronic fixation. Dysbacteriosis of organ dyhannya pro
theca in the form of bronchitis, chronic ailments
lungs. The main manifestations of oral emptying dysbiosis
є gingiviti, stomatitis, caries. dysbacteriosis status
systems in women against vaginosis.
Falsely from the turn of the cichs showing the development
a few phases of dysbacteriosis:
1) compensated, if dysbacteriosis is NOT accompanied -
be-like clever manifestations;
2) subcompensated, if as a result of an imbalance of normal
small microflori are found in local igniters
snakes;
3) decompensated, when a general
the process of diagnosing metastatic inflammations
tilnyh vognisch.
Laboratory diagnostics of dysbacteriosis
The main method is bacteriological dosage. With tsom
in the assessment of yogo results prevail the number of indicators.
It is not carried out a species identification, but only to the kind.
39
Dodatkovy method - chromatography of the spectrum of fatty
acids in pre-juvenile materials. To the skin type
own spectrum of fatty acids.
Correction of dysbacteriosis:
1) the reason why the imbalance is normal
microflori;
2) registration of eubiotics and arrivals.
Eubotics are drugs that can take revenge on live bacteria.
normal microflori (colibacterin, bi-
fidumbakterin, bifikol and in.).
Pributok - the center of non-microbial trekking
і products of food, scho to revenge additives, scho to stimulate
normal normal microflora. Stimulating speeches -
oligosaccharides, casein hydrolyzate, mucin, milk syrovatka,
lactoferin, grain fibers.

1. Normal microflora of people

Normal microflora of people is the price of impossibility of microbiocenoses, which are characterized by singular relationships and a sense of living.

In the organism of people, it is obvious to the minds of living that biotopes are formed with the singing microbiocenosis. Whether microbiocoenosis is the wholeness of microorganisms, but it’s just the same, tied with lancet and microecology.

See normal microflori:

1) resident - permanent, typical for a given species;

2) transient - time-consuming, uncharacteristic for a given biotope; won’t actively multiply.

Normal microflora is formed from the people. On її the formulation is infused with the microflora of the mother and the internal environment, the nature of the vygodovvannya.

Factories that pour normal microflori into the mill.

1. Endogenous:

1) secretory function of the body;

2) hormonal background;

3) acid-tin mill.

2. Exogenous mind of life (climatic, pobutov, ecologic).

Microbial zabrudnennya is characteristic of all systems, so there is no contact with the navkolishnіm middle. In human organisms, they are sterile - shelter, liquor, suglobova ridina, pleural ridina, lymph of the thoracic duct, internal organisms: heart, brain, liver parenchyma, nirok, spleen, uterus, chaff, alveoli of the leg.

The microflora of the vistila of the mucous membrane is normal in the viglyad of the bioplastic. The whole polysaccharide framework is stored with polysaccharides in microbial cells and mucin. New microcolonies of normal microflora are found. Biscuit production - 0.1-0.5 mm. They can be found from hundreds to thousands of microcolonies.

Formation of biodiesel for bacteria of the sash. In the middle of the bacterium biodiesel, there are more steps to the number of chemical and physical factors.

Etapi formulating normal microflora of the shlunkovo-intestinal tract (QCT):

1) vypadkovo obsіmenіnnya slizoї. In the intestinal tract, lactobacilli, clostridia, bifidobacteria, micrococci, staphylococci, enterococci, intestinal sticks are consumed;

2) the formation of hedgehogs from line bacteria on the surface of the villi. They are fixed in the main bacterium-like bacteria, gradually the process of forming the bioplast.

Normal microflora is seen as an independent extracorporeal organ with anatomical structure and functions.

Function of normal microfloria:

1) participation in all types of exchange;

2) detoxification of ekzo- and endoproducts, transformation and vision of lykarsky speeches;

3) participation in the synthesis of vitamins (groups B, E, H, K);

4) zahist:

a) antagonistic (linked to the production of bacteria);

b) colonization resistance of mucous membranes;

5) immunogenic function.

The most abundant contamination is characterized by:

1) good intestine;

2) empty mouth;

3) sectional system;

4) upper dichalny ways;

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