Penicilin sodium sil instructions. Benzylpenicillin - drugs (sodium hydrochloride, calyna sil, novokainova sil, benzylpenicillin benzathine and in.),

antibacterials

describe

powder for preparation of rosters for ін'єкцій and місція preparation 500,000 MO, 1,000,000 OD

Pharmacotherapeutic group

antibiotic-penicilin biosynthetic

Trade name

Benzylpenicillin sodium

International non-patented name

benzylpenicillin

Lykarska form

powder for preparing the size for ін'єкцій and місцевого зосування.

warehouse

Active speech: Benzylpenicillin sodium (benzylpenicillin sodium sodium) - 500,000 OD і 1,000,000 OD.

ATX code

Pharmacological authorities

Pharmacodynamics
Bactericidal antibiotic from the group of biosynthetic ("natural") penicilines. Applied synthesis of microorganisms' culture. Active relatively gram-positive pupils: Staphylococcus spp. (Non-forming penicylinase), Streptococcus spp. (Including Streptococcus pneumoniae), Сorynebacterium spp. (Including Corynebacterium diphtheriae), Bacillus anthracis, Actinomyces spp .; gram-negative microorganisms: Neisseria gonorrhoeae, Neisseria meningitidis, and also Treponema spp., class Spirochaetes. Chi is not active, with a relatively large amount of gram-negative bacteria (including Pseudomonas aeruginosa), Rickettsia spp., Viruses, the simplest. Prior to the preparation of Staphylococcus spp., Staphylococcus spp., Yaki produce penicylinase.
Pharmacokinetics
The hour required to reach the maximum concentration in the blood plasma with an internal test is 20-30 min. Coupling with plasma beads - 60%. Penetrates into organisms, fabrics and biological lines, rim liquor, tissues of the eye and anterior mucosa, when the meningeal membranes are inflamed, it penetrates through the hematoencephalic bar. Vivoditsya nirkami in an invincible viglyad. Period of napivvivedennya 30-60 min, at nirkova lack- 4-10 years and older.

Shown to sucking

bacterial infections, Viklikan are sensitive to penicilians: Posal carnial pneumonia, Empієma pleurisy, bronchitis; sepsis, septic endocarditis (gostria and pidgostria), peritonitis; meningit; osteomyelitis; інфекції sectional system(Pієlonephritis, pієlіt, cystitis, urethritis, cervicitis), zhovchivіdnyh shlakhіv (cholangіt, cholecystitis); wound infection, infection of the skin and soft tissues: rabies, impetigo, secondarily infections of dermatoses; diphtheria; scarlet fever; sibirska virazka; actinomycosis; Infections of ENT organs, eye problems (gostry conjunctivitis, twisting of horns and in.); gonorrhea, syphilis.

Prototype

Hypersensitivity, including up to the largest penicilines, cephalosporins.

Stagnation with vaginosti

Stagnation of the drug in the period of vaginosity is possible only in that case, if the cinnamon is transferred to the mother, the potential risik for the fetus is transferred.
If necessary, the drug is prescribed in the period of lactation, when the breast is tightened.

How to store that dosi

Benzylpenicillin and sodium hydroxide should be injected internally, internally, podshkirno, micevo.
Internal and internal:with a moderate interruption of the disease (infections of the upper and lower dikhalnyh nobles, Secovivnyh and zhovchividnyh nobles, infectious diseases of soft tissues and in.) - 4-6 million units / day for 4 introduction. In case of severe interruption of infectious diseases (sepsis, septic endocarditis, meningit and in.) - 10-20 million OD / dobu; with gas gangrene - up to 40-60 million OD / add.
dobova dose for children in vіtsі up to 1 rock - 50-100 yew. OD / kg, older than 1 rock - 50 yew. OD / kg; if necessary - 200-300 yew. OD / kg, according to "life" is shown - up to 500 yew. OD / kg. Multiplicity of introduction: internally - 4-6 times for additional, internally - 1-2 times for additional in addition with internal references.

pidshkirno for coloration of filtration at a concentration of 100-200 yew. OD in 1 ml 0.25-0.5% procaine.

At the empty (Cherevnu, pleural and in.) Roschin benzylpenicillin and sodium salt are grown to be injected in a concentration of 10-20 thousand. OD in 1 ml, children - 2-5 yew. OD in 1 ml. Yak razchinnik vikoristovutsya water for ін'єкцій or 0.9% razchin sodium chloride. Triviality lіkuvannya 5-7 days with a further transition to the internal language introduction.
When the eyes fallacknowledge full blobs, Шо revenge 20-100 yew. OD in 1 ml of sterile 0.9% sodium chloride or distilled water. Introduce 1-2 drops 6-8 times a day. Rozchin vikoristoyut freshly made by him
For vushnyh krapel abo krapel in n_szasosovuyut razchini, yak_revenge 10-100 yew. OD in 1 ml of sterile 0.9% sodium chloride or distilled water. Introduce 1-2 drops 6-8 times a day.
The triviality of benzylpenicillin mucus in the presence of form and severity of disease is 7-10 days.

How to prepare solutions

Roschini vikoristovuyut immediately after preparation, do not allow any additional information to them lykarsky zasobiv.

For internal introduction to the vial, add 1-3 ml of water for injections, 0.9% sodium chloride or 0.5% procaine (novokain). Introduce otrimany rozchin gliboko into myaz.

When diluted benzylpenicillin and in the case of procaine, it is possible to prevent a cloudy growth in the inheritance of crystals of benzylpenicillin procaine, but it is not a transient for intravascular and pediatric drug administration.

For internal struma injection, a single dose (1-2 million OD) is adjusted in 5-10 ml of sterile water for injections, or 0.9% sodium chloride range and should be injected every 3-5 minutes.

For internal speckled introduction, 2-5 million OD to dilute 100-200 ml of 0.9% sodium chloride, or 5-10% glucose, and inject 60-80 drops / min. When dots are introduced to children, they crumble with 5-10% glucose solution (30-100 ml fallow in a dose of vіku).

For pediatric introduction vmist the bottle is to be diluted in 0.25-0.5% procaine: 500 yew. OD in 2.5-5 ml, 1 mln. IU in 5-10 ml as appropriate.

For vnutr_shnyoporozhninnaya introduction vm_st the bottle, dilute in 0.9% solution of sodium chloride, or in water for іn'єktsіy: grow up - 500 yew. OD in 25-50 ml, 1 million OD in 50-100 ml, for children - 500 yew. OD in 100-250 ml, 1 million OD in 200-500 ml, as appropriate.
Ochnі droplets slіd gotuvati ex tempore: instead of the bottle to be diluted in 0.9% solution of sodium chloride or distilled water: 500 yew. OD in 5-25 ml, 1 million OD in 10-50 ml as appropriate.

Pobichna diya

Allergic reactions: hyperthermia, kropiv'yanka, shkirny visip, visip on mucous membranes, arthralgia, eosinophilia, angioedema, interstitial nephritis, Bronchospasm, anaphylactic shock. On the cob to the rate of illusion (especially in cases of congenital syphilis) - feverishness, chills, increased sweatiness, aggravated illness, reaction of Yarish-Herxheimer.

Three sides heart-vascular system- impairment of the pumping function of the myocardium, arrhythmias, zupinka heart, chronic heart failure (that is, with the introduction of large doses, hypertension can occur).

Miscellaneous reactions: soreness and pain in the introduction.

With trivial stasis: dysbacteriosis, development of superinfection.

If you are because of the meanings in the instructions for the secondary effects, you will get lost, if you remembered whether you are side effects not specified in the instructions, see about the doctor.

Overdose

appear toxic food to the central nervous system(Judge, head bill, Bil at the m'yaz, be at the slopes).

Likuvannya is symptomatic.

Stagnation with other drugs

Bactericidal antibiotics (including cephalosporin, vancomycin, rifampicin, aminoglycoside) repair a synergistic effect; bacteriostatic (including macrolide, chloramphenicol, lincosamide, tetracycline) - antagonistic.

Increasing the effectiveness of indirect anticoagulants (attracting intestinal microflora, lowering prothrombin index); lowering the effectiveness of oral contraceptives, drugs, in the process of metabolism of which paraaminobenzoic acid is established.

Diuretics, alopurinol, tubular secretion blockers, phenylbutazone, non-steroidal antiapalnic drugs that reduce tubular secretion, increase the concentration of benzylpenicilin.

Alopurinol promotes the development of allergic reactions (shkirnoy visipki).

special requests

The preparation should be prepared without prescription before the introduction. Even after 2-3 days (maximum 5 days), when an ear of the drug is consumed, it does not seem to be effective, it is necessary to proceed to the consumption of other antibiotics or combined therapy. At the connection with the possibility of development of fungal lesions, docitally in case of trivial use of benzylpenicillin, the sign of vitamins group B, and if necessary - anti-fungal drugs... It is necessary to vrahovuvati, so that insufficient doses of the drug are consumed, or early recovery of the drug is often produced before the emergence of resistant strains of zbudniki.

After an hour of the introduction of the drug, it is necessary to take care of the care in case of keruvanny by motor transport, mechanisms and in the case of other potentially unsafe types of activity, as well as to reduce the increased concentration of respect for the reaction.

Form vipusku

ін'єкційні preparations

Form vipusku

Powder for preparing a size for in-and-out and microscope consumption 50,000 OD, 1,000,000 OD.
For 500,000 OD and 1,000,000 OD of active speech, the bottle contains 10 ml or 20 ml, hermetically sealed with gum corks, crimped with aluminum corks, or combined with aluminum and plastic kryshki.
1, 5, 10 vials at once with the instructions from the filling are put into a pack of cardboard.
50 bottles can be packed in a box of cardboard with an additional amount of instructions and supplies for delivery to the hospital.

Umovi zberigannya

In dry food at temperatures from 15 to 25 ° С.

Term of attachment

3 rock. Do not store the drug after the end of the term of adherence indicated on the package.

Benzylpenicillin - drugs (sodium hydrochloride, calyna sil, novokainova sil, benzylpenicillin benzathine and in.),

thank you

The site has been provided with information for general information. Diagnostics and diagnosis of illnesses needs to be carried out before visualization. All drugs have a contraindication. Consultation by fakhivtsya obov'yazkov!

Rіznodydi, name, warehouse, form vipusku that characterization

Oskilki Benzylpenicillin is practically not wet in herbal tract, Yogo to enter viklyuchno ін'єкційно. It is often the case that the drug should be administered internally or internally. However, in addition, benzylpenicillin can be injected into the spinal canal (in case of meningitis), or even in the area of ​​the wound.

Benzylpenicillin is an antibiotic, which is not active in revenge. However, in drugs benzylpenicillin is found not in pure viglyad, but in the form of salts. Salt benzylpenicylinu stiyki and can take on, in the form of pure active speech, so quickly fall off. In the body of salts, benzylpenicillin grows and rubs the teeth on bacteria.

This is due to the fact that benzylpenicillin is in the form of benzylpenicillin in the same drug as benzylpenicillin. In principle, all types of Benzylpenicillin are the same for their spectrum of action, but are considered for the trivial effect and methods of administration. Tom with dear ones it is recommended to take the appropriate preparation, as it is optimal to go for the duration of the therapy.

In the Danish hour, such types of benzylpenicilin are used:

• Benzylpenicillin sodium sil ( trade name preparations - "Benzylpenicillin sodium chloride", "Novotsin", Penicilin G);
• Benzylpenicillin kaliev sil (the trade name of the drug is "Benzylpenicillin kaliev sil");
• Benzylpenicillin novocaine sil (the trade name of the drug is "Benzylpenicillin novocaine sil");
• Benzylpenicillin procaine sil (trade name of the drug - "Procain Penicilin");
• Benzathine benzylpenicillin (trade name of the drug - "Retarpen", Extensilin, Bitsillin-1, benzathinbenzylpenicillin, Moldamin);
• Bitsillin-5 (sum of benzathine and procaine salts of penicillin).

All types of Benzylpenicillin are dispensed in a single lykarsky form - a powder for preparing a variety of products. Powder of premises in flasks, corked with gum pouches, covered with aluminum foil on top. The vials, in the form of packaging antibiotic powder, are called "penicilinovyh".

Benzylpenicillin - drugs

• Benzylpenicillin kalive sil;
• Benzylpenicillin sodium sil;
• Benzylpenicillin novocaine sil;
• benzathinbenzylpenicillin;
• Bicillin-1 (benzathine benzylpenicilin);
• Bicillin-3 (sum of benzathine, sodium and procaine salts of penicillin);
• Bitsillin-5 (sum of benzathine and procaine salts of penicillin);
• Moldamin (benzathine benzylpenicilin);
• Novotsin (benzylpenicylin sodium sodium sil);
• Penicilin G (benzylpenicilin sodium sil);
• Procaine Penicilin (benzylpenicilin procaine sil);
• Retarpen (benzathine benzylpenicilin);
• Extensilin (benzathine benzylpenicilin).

Diya

Benzylpenicillin penetrates into the mustache and tissue, and that can be used for treatment Infectious diseases small localization, as the stench provoked by sensitive bacteria.

All types of Benzylpenicillin are injected into the teeth on the onset of pathogenic microorganisms:

• Gonococci (Neisseria gonorrheae);
• Meningokoks (Neisseria meningitidis);
• Staphylococcus, which do not viroblast penicylinase;
• Streptococcus groups A, B, C, G, L and M;
• enterococks;
• Alcaligenes faecalis;
• Actinomycetes;
• Bacillus anthracis;
• Clostridiae;
• Corynebacterium diphtheriae;
• Erysipelothrix insidosa;
• Fusobacterium fusiforme;
• Leptospirae;
• Pasteurella multocida;
• Spirilllim minus;
• Spirochaetaceae (syphilis, yaws, lime-boreliasis, etc.);
• Streptobacillus moniliformis;
• Treponema pallidum.

Shown to sucking

Natreva, kaliev, novokainova and procaine salts of benzylpenicilin

• Infectious diseases of the organs of the disease (pneumonia, pleurisy, pleurisy, bronchitis, etc.);
• Infectious diseases of ENT organs (angina, scarlet fever, otitis media, sinusitis, laryngitis, sinusitis, etc.);
• Infections of organs in the sechostatus tract (gonorrhea, syphilis, cystitis, urethritis, adnexitis, salpingitis);
• Gnіynі infections of the eye, mucous membranes, shkіri and cystoks (for example, blenorrhea, blepharitis, dacryocystitis, mediastinitis, osteomyelitis, phlegmon, madness, D. іnfektsіya wound, gazova gang.
• Gnіynі menіngіti or abscess to the brain;
• Sepsis or septicemia;
• Lіkuvannya zhvoryuvan, wiklikani spirochetes, such as syphilis, yaws, pinta, Siberian virazka, etc.;
• Likuvannya fever, provoked by squinting bites;
• Lіkuvannya іnfektsіy, scho vyklicayutsya Clostridia, listeria and Pasteurella;
• Prevention and treatment of diphtheria;
• Prevention and treatment acceleration streptococcal infections Such as rheumatism, endocarditis and glomerulonephritis.

Preparations for revealing benzylpenicylin benzathine

• Triva prevention of recurrence of rheumatism;
• syphilis;
• yaws;
• Infections, caused by streptococcus group B, such as tonsillitis, scarlet fever, early infections, erysipelas;
• Prevention of operational infections.

Instructions for storing

Rules for the selection of salts of benzylpenicilin

Benzylpenicillin benzathine is optimal for the treatment of chronic infections and prevention of children infectious diseases... To that drug, which is given to avenge, has been victorious for the trivial therapy of chronic chronic ailments.

When benzylpenicillin is consumed in high doses (20,000,000 OD per dose) for more than five days, it is necessary to control the concentration of electrolytes in the blood (calories, calcium, sodium, chlorine), liver function І picture of blood (gross analysis of blood from leukoformula).

People who consume benzylpenicillin may have a pseudo-positive reaction to sugar.

People who are suffering from diabetes have an antibiotic soaked into their homes, so they need to fix that drug more.

Oscillations of benzylpenicillin consumption can lead to the development of fungal infection, then it is recommended to take prophylactically

Instructions on the intake of Benzylpenicillin sodium salt for injections
for treating food with ailments of bacterial etiology
(Organization-robnik: ZAT NVP "Agrofarm", m Voronezh)

I. Headquarters
Trade nymenuvannya lykarsky drug: Benzylpenicillin natrium pro injectionibus.
International non-patented naming: Benzylpenicilin sodium sil.

Likarska form: powder for preparing a rose for ін'єкцій.
The drug, in the context of a daily speech, is to take revenge on benzylpenicylin sodium hydroxide - not less than 1650 OD / mg (in a dry way).
per zovnishnim viglyadom the drug is a dibnocrystalline powder of a white or slightly chewy color.

Vipuskayut drug in sterile viglyadі powder, packaged in 1,000,000 OD in vials, sealed with gum stoppers, reinforced with aluminum cups.

Take the drug in a closed package of vyrobnik in a dry, stolen form of light, okremo from food and feed, at temperatures from 5 ° C to 25 ° C.
The term of attachment to a drug in the minds of a zbergannya
When the vial opens, the drug is not suitable for use.
Zaboronyaєya zasosuvannya pis for the end of the term of attachment.
Benzylpenicillin sodium hydrochloride for inaccessible children.
Nevikoristaniy lykarsky drug is disposed of according to the legislation.

II. Pharmacological authorities
Benzylpenicillin sodium chloride is used before antibacterial drugs from the group of β-lactam antibiotics.
Benzylpenicillin is active in generally gram-positive microorganisms (streptococci, gramopoietic organisms, pneumococci, enterococks, more anaerobes, actinomycetes, clostridia, hypochondriacal bacteria) Ineffective, albeit a large number of gram-negative bacteria, rickets, viruses, most common, fungi, as well as microorganisms, which violated penicillinase.
Mechanism of bactericidal activity of transpeptidase and carboxypeptidase synthesis on impaired synthesis of peptidoglycan, so that it can enter the storehouse of microorganisms, by means of transferring enzymes in transpeptidase and carboxypeptidase, so that the balance of microorganisms is broken down.
Benzylpenicillin, when administered internally, quickly soaks into the roof of the skin and easily penetrates into a large number of organs and tissues. The maximum concentration of antibiotics in the blood is reached through 30-60 quilins, the therapeutic concentration in the organs and tissues is reduced for 4-6 years. Benzylpenicillin is introduced into the organism in an unchanged view in the main part and in small quantities in the gum, in lactating brews in milk.

Benzylpenicillin sodium sil behind a step is injected onto the organism according to GOST 12.1.007-76, it should be referred to the rivers that are not safe (3 classes are not safe), in the recommended doses, do not repair the miscellaneous.

III. procedure for sucking
Benzylpenicillin natrієvu sіl for іn'єktsіy zastosovuyut sіlskogospodarskim tvarinam, Hutrovit zvіram i dogs for lіkuvannya pasterelozu, bronhopnevmonії, zahvoryuvan sechostatevoї system mastitis, nekrobakterioza, streptokokovoї septitsemії, stafilokokkoz, actinomycosis, emfіzematoznogo carbuncle, i pіslyapologovogo wound sepsis and takozh іnshih Parvin i vtorinnih іnfektsіy, іklikanikh zabudnikami, sensitive to penіtsilіnіv.

Prototype indications before the drug is consumed є the individual sensitivity of the creature to the antibiotics of the penicilin group has been adjusted.

Before filling the bottle, by piercing the bottle cap and the cork of the bottle with a bare bottle, dispense 5-10 ml of water for sterile and ultra-tonic sodium chloride.
Liquidity needs to be prepared without the middle before the introductions, it is not for the sake of the selection and heating.
The drug is administered internally with an interval of 4-6 years for a length of 5-7 dB, with important forms of ailment - up to 10 dB, in doses indicated in the table (with a dose of OD of a daily speech per 1 kg of a food of a creature):

* Note: young animals of great horny thinness and pigs - up to 6 months old, other horny thinness - up to 4 months old, horses, dogs and farm animals - up to 1 month.

In case of an overdose of the drug in a creature, neurotoxic symptoms (nudity, bloating, increased reflexiveness) may be stimulated. In cich vipadkah, the drug is pinched and marked for symptomatic therapy.

The peculiarities of the drug for the first time have not been revealed.

Slid unique to skipping the drug dose, so as it can lead to a decrease in its therapeutic efficacy. If you miss one dose, the drug is taken from the same dose and according to the same scheme.

With the intake of benzylpenicillin sodium salt for the first time, according to the instructions side effects and quickening in creatures, as a rule, do not be spared. With an increase in the individual sensitivity of the food to antibiotics in the peniciline series, in the food, allergic reactions develop quickly (crotch, diarrhea, angioedema, anneurotic shock) At the same time, the use of the drug should be tightened and desensitized therapy should be performed.

Do not allow the intake of benzylpenicillin sodium salt for antibiotics in one hour with bacteriostatic antibiotics (aminoglycosides, tetracyclines, levomycetin), adrenaline, euphilin, ascorbic acid antibiotics drugs.

Slaughter the food for meat is allowed not earlier, not after 3 add the last meal of the benzylpenicillin sodium salt for the inking.
The meat of the food, which has been slaughtered to the end of the designated term, can be used as a vicoristan in the fodder of the meat of the food.
Milk, taken from food during the period of drinking and for 24 years after the rest of the introduction of the drug, is taken away from food for food purposes. Also, milk produced from thermal processing can be used as vicoristano in food for creatures.

IV. Come in special prophylaxis
When carried out lіkuvalnyh visits With the help of benzylpenicillin sodium chloride for the first time, the rules of special hygiene and technology are safe for transferring when robots are used. It takes an hour to take the drug to drink, smoke and take it. Pislya ending robots hands slid vimiti warm water with cute.
People who are hypersensitive to antibiotics of the penicillin group should only have direct contact with benzylpenicillin sodium for the first time. In case of a bad drug hitting a drug on his skin, it is necessary to safely take it with water and sweet water, if it gets into the eyes, it must be washed out with a drop of liquid quiline in running water. If you have any allergic reactions, or if a drug gets into the body of a person, it will inadvertently turn into medical pledge(If you have a mother, you will need a label or a label).

Zaboronyae vikorystannya empty vials z-pіd lykarskogo drug for whitewash purposes.

Organizatsiya-virobnik: ZAT NVP "Agrofarm", Russia, 394087, Voronezka region, M Voronezh, vul. Lomonosov, 114-b.

Thanks to the solidification of the structure of the instruction, the force of the instruction was consumed from the consumption of benzylpenicylin sodium salt for the injection, approved by the Russian State Scientific Committee on the 29th of April 2006 r

Release form: Рідкі lykarski formi... Rozchin for ін'єкцій.

General characteristics. warehouse:

Pharmacological authorities:

Shown to stasis:

Important! Get to know the likuvannyam,

How to store that dose:

Features of storing:

Pobichna diya:

Vzaєmodia with іnshy lіkarskiy zasob:

Prototype indications:

Overdose:

Umovi zberigannya:

In dry food at temperatures not as high as 20 ° C. Zberigati is out of reach of children. The term of attachment 3 rocks. Do not store the drug after the end of the term of adherence indicated on the package.

Umovi vidpustki:

For the recipe

package:

Powder for the preparation of razchino for internal injection of 500,000 Odes, 1,000,000 Odes per bottle. For 50 bottles at once with instructions for filling in a box of cardboard (for stationary).

Registration number: P N003271 / 02-060810

Trade name of the drug: Benzylpenicillin

International non-patented name (INN): benzylpenicilin

Lykarska form: Powder for preparing the size for internal and secondary injection.

warehouse:
Benzylpenicillin sodium per pererakhunka per active line - 500,000 OD, 1,000,000 OD

describe: White powder with a weak characteristic odor.

Pharmacotherapeutic group: Antibiotic-penicilin biosynthetic
ATX code J01CE01

Pharmacological authorities
Pharmacodynamics
Bactericidal antibiotic from the group of biosynthetic "natural" penicilines. Applied synthesis of microorganisms' culture. Active relatively gram-positive pupils: Staphylococcus spp. (Non-forming penicylinase), Streptococcus spp. (Including Streptococcus pneumoniae), Corynebacterium diphtheriae, Bacillus anthracis, Actinomyces spp .; gram-negative microorganisms: Neisseria gonorrhoeae, Neisseria meningitidis, as well as the Spirochaetes class, including Treponema spp. Chi is not effective, but rather large gram-negative bacteria, Rickettsia spp., Nayprostish. Prior to the preparation of the stiyky penicylinase-containing microorganisms.

Pharmacokinetics
The hour of reaching the maximum concentration (ТСmах) with internal injection is 20-30 minutes. Coupling with plasma beads - 60%. Penetrates into organisms, fabrics and biological lines, rim liquor, tissues of the eye and anterior mucus, when the meningeal membranes are inflamed, it penetrates through the hematoencephalic bar (HEB). Vivoditsya nirkami in an invincible viglyad. Period of napivvedennya (T½) is 30-60 hvili, with nirkovy deficiency - 4-10 years or more.

Shown to sucking
Infectious-igniting illnesses, viclikans sensitive to the preparation of the drug:

• organ_v dikhannya: Posal carnial pneumonia, pleural effusion, bronchitis;
• ENT organs;
• sechostatic system: polyonephritis, pyulitis, cystitis, urethritis, cervicitis;
• young people: Cholangitis, cholecystitis;
• shkіri і soft fabrics: Beshiha, impetigo, secondarily diagnosed dermatoses, wound infections;
• ill eyes: Gonoblenorrhea, horny twisting;
• sepsis, septic endocarditis (gostry і pidgostria),
• peritonitis;
• gonorrhea, syphilis;
• meningit;
• osteomyelitis;
• diphtheria; scarlet fever; actinomycosis; sibirska virazka.

With protection
Allergic illnesses ( bronchial asthma, Polinosis), nirkova lack.

Stagnation during vaginosis and breastfeeding
Zastosuvannya with vaginosti is possible, as well as transferring cinnamon for the mother, changing the potential risik for the fetus. If necessary, the drug should be taken during the period of lactation and should be tightened to the breast.

How to store that dosi
Intrashnyom'yazovo, pіdshkіrno.
Internally, with a moderately severe interruption of infections of the upper and lower branches, the second and the last, the infection of the soft tissues and in.
- 2.5-5 mln. OD for 4 introductions for dobu.
Dobova dose for children under 1 roku - 50,000-100,000 OD / kg, older than 1 roku - 50,000 OD / kg; if necessary - 200000-300000 OD / kg; according to "life" is shown - increase up to 500,000 OD / kg. The multiplicity of the introduction is 4-6 times for extra.
Podshkirno for coloration of infiltrates at a concentration of 100000-200000 OD in 1 ml 0.25-0.5% procaine.
When the eyes fall: Extra drops in a concentration of 20,000-100,000 OD in 1 ml of 0.9% solution of sodium chloride or distilled water, 1-2 drops 6-8 times per day.
The triviality of treatment with the drug is fallen due to the form and severity of the disease, 7-10 days.

How to prepare solutions
The preparation for internal injection should be prepared without pre-injection, adding 1-3 ml of water for injection or 0.9% sodium chloride, or 0.5% procaine, to the vial.
When diluted with benzylpenicillin in the form of procaine, it is possible to prevent the clouding of the problem in the case of the establishment of crystals of benzylpenicillin procaine, but it is not a transition for an internal pelvic drug. Razchini vikoristovuyut all at once by preparing, do not allow the addition to them of the second likarsky zasob_v.
Raschin for muscular congestion in ophthalmology slid gotuvati ex tempore: instead of the bottle, dilute in 0.9% solution of sodium chloride or distilled water - 500,000 OD in 5 -25 ml, 1 million OD in 10-50 ml as appropriate.

Pobichna diya
allergic reactions: Hyperthermia, kropiv'yanka, shkirny visip, visip on mucous membranes, arthralgia, eosinophilia, angioedema, interstitial nephritis, bronchospasm; Ridko - anaphylactic shock. On the ear to the rate of illusion (especially in the case of congenital syphilis), it is a little feverish, chills, podvischenia sweaty, stinging sickness, reaction of Yarish-Herxheimer.
On the side of the heart-vascular system: Decreased fraction of the myocardial arrhythmia, heart zupinka, chronic heart failure (this can be caused by hypernatria with the introduction of large doses).
miscellaneous reactions: Ailments and disadvantages in the internal language introduction
іnshe: With trivial stasis dysbacteriosis, development of superinfection.

Overdose
symptoms: Judge, loss of evidence.
lykuvannya: Vidmina drug, symptomatic therapy.

Vzamodia with інshih lykarsky preparations
Bactericidal antibiotics (including cephalosporin, vancomycin, rifampicin aminoglycoside) repair a synergistic effect; bacteriostatic (including macrolide, chloramphenicol, linkosamide, tetracycline) - antagonistic effect of indirect anticoagulants (inhibiting intestinal microflora); lowering the effectiveness of oral contraceptives in drug use, in the process of metabolism of which para-aminobenzoic acid is established - the risk of development of bleeding "break through".
Diuretics, alopurinol, tubular secretion blockers, phenylbutazone, non-steroidal antiapalnic drugs that reduce tubular secretion, increase the concentration of benzylpenicilin.
Alopurinol promotes the development of allergic reactions (shkirnoy visipki).

special requests
Even after 2-3 days (maximum 5 days), when an ear of the drug is consumed, it does not seem to be effective, it is necessary to proceed to the consumption of other antibiotics or combined therapy. At the connection with the possibility of development of fungal lesions, in case of trivial use of benzylpenicillin, the sign of vitamins of group B is indicated, if necessary - anti-fungal drugs. It is necessary to vrahovuvati, so that insufficient doses of the drug are consumed, or early recovery of the drug is often produced before the emergence of resistant strains of zbudniki.
Due to the infusion of the drug on the health of the keruvati by transport means and other mechanisms of the day. However, I look at the moss pobichna diya on the side of the heart-vascular system, followed by protection during employment of this kind of activity.

Form vipusku
Powder for preparing the size for internal and secondary injection of 500,000 OD, 1,000,000 OD in a bottle of 10 ml.
1 bottle at once from the instructions from the filling to the pack.
10 bottles at once from the instructions from the filling into the box from the cardboard box.
For the stationary: 50 bottles and 5 instructions from the storage place in a box from a cardboard box.

Umovi zberigannya
List B. From a stolen light at a temperature of 25 ° C.
Zberigati is out of reach for children.

Term of attachment
Z rock. Do not fix the term for endowment.

Mind that term zberigannya
For the recipe.

Claims from buyers of acceptance
VAT "Kraspharma"
Russia 660042 m Krasnoyarsk, vul. 60 rockiv Zhovtnya, bud. 2.