Suggestions about the intake of articaine in dentistry and instructions before the drug. Articain - instructions, storing, counter-indications, secondary actions articaining

) - doctor-dentist-therapist, dentist-periodontist. Specialized in the field of endodontics, esthetic and functional restoration, professional hygiene and periodontology.

In a given hour in the dentistry practice, there are no new methods of medicine and medications, so that you can be used to carry out microbial zenology. The drug "Vibor", used for medical anesthesia, in dentistry є Artikain.

Forward Artikain buv syntheses in 1969 roci, since 1976 rock to fix yogo wider sucking... at a time lіkuvalny drugs on the basis of artikainu are issued by bagatma pharmaceutical companies.

Main vimogi, up to micevo-anesthetics:

• Glybina is a sign of the penetration of Koshty;
• triviality of the action;
• high step bezpeka.

On the given parameters, inflate:

• the activity of anesthetic anesthetic;
• the tone of the peripheral sudin.

The drug Articain cannot be stored in the warehouse especially as a preservative - paraben, which is the most frequent cause of hypersensitivity reactions. Reveal the minimum amount of the antioxidant adrenaline (metabisulfite).

The stability of the microanesthesia can be reached beyond the additional high quality of the warehouse, the humic storage carpool, the high activity of the industrial speech.

It’s not a fault of being in the middle of the water; For the manifestation of the main effects of the necessary ruinization in the tissues with the statements of the fatty ridges, as they penetrate through the lipid sheath of the nervous termination. To deliver a shyly arrogant change in fabric structures, to that zealous dіyu vіdnіnuyut already in 1-2 hviliiny.

Artikain is insignificant before the expansion of the education of blood-bearing vessels, that is, to the extent that adrenaline (adrenaline) is achieved. Shvidko penetrates into the flesh of fabrics, as well as into the cyst structures, so that the patient will not be able to read it, as well as being widely used in therapeutic, surgical, orthopedic procedures in dentistry.

It is produced in the form of cartridges and rozchinіv for іn'єktsіy introduction in ampoules. Packed in cardboard boxes.

Pharmacological diya

The mechanism of the installation on the inflow to the end of both sensitive nerves and nerve fibers, which is used to destroy the generation of an awkward impulse and its conduction to the other structures. Articain interacts with receptors, which are responsible for the robot on certain channels. When pouring in on them, the blocking of the struma of ions with sodium through them is added, in which case an anesthetic effect develops.

The triviality of the game is to become close to 20 khvili. Rush up to non-toxic products for the body, which gives the possibility of re-introduction of speech. In a sour middle, the effectiveness of the drug decreases.

analogs

release of art_ka_ncontaining Lykarskiy rechovin carried out by pharmaceutical companies. Stink to carry the following patented name:

• Alfakain (virobnistvo - France);
• Artikain Іnbis (country-virobnik - Іspania);
• Ubestezin (virobnistvo - Nimechchina);
• Primakain (country-virobnik - France);
• Cytocorin (virobnitstvo - Italia);
• Ultrakain (country-virobnik - Nimechchina);
• Septanest (virobnistvo - France).

Pharmacokinetics and pharmacodynamics

Articulation will provide a high level of activity and a minimal number of unpleasant reactions to the body. Volodya minimal toxicity. The maximum concentration of food introduced into the sub-layer of the shell mouthwash Validate after 25 minutes after the introduction. In case of infiltrative anesthesia, the effect is to be observed after 1-2 chilin, with provincial anesthesia - after 2-2.5 chilin.

Yogo transformation of a person is seen in the liver, as well as the process of inactivation of the bloodstream and tissue structures under the influence of enzymes in blood plasma (cholinesterase). Otrimuvani metabolites do not cause anesthesia. To clink with blood beads, vivoditsya nirkami. I will add about half of the administered dose.

So, since it is strong until the expansion of blood-bearing vessels, then most often it is shown vikorystannya with adrenaline - zasob, like viklikє spasm of sudin.

adrenaline

Є alpha-, beta-adenomimetic method. Stimulating adrenergic receptors, leading to a cascade of biochemical reactions, the result of which is an increase or a decrease in the concentration of calcium ions in cells (an increase or a decrease in functional cell activity). The functional activity is non-mediated to the type of biochemical processes, as well as to the type of receptor, on the yak being injected.

You can use those in the judges internal organs to take revenge on clientele of smooth muzzles, like alpha-adrenergic receptors on their surface. Injection on them veda until fast klin, pidsumok - zvuzhennya enlightenment of sudin. The health of the victim is a spasm of vertebral deformities and mucous membranes, as there is a lot of blood flow in a given region, to be victorious to reduce the performance of the muscular anesthetics of the three times.

showing

In the wake of vikoristoyutsya concentration, to look at the lykarsky zasib is not a superficial-anesthetic activity, albeit when injected into the drug by the way of overturning the drugs of the group (, Mepivakain). The main indications are prior to vikorystannya artikainu є micev anesthesia of the provincial or infiltrative type.

Articaine with adrenaline vikoristovuyutsya for the fever of traumatic dentists in the viglyadi of the advancing species of the muscular fever:

• іnfіltratsіyna (leaking tissue of the operative field);
• Providnikova (introduction of speech along the nerve);
• Intraligamentary (internal ligamentous);
• Intraseptal (intraseptal - the tongue is inserted into the septum of the brush between the holes of the teeth);
• intrapulpal (the introduction of anesthetic into the pulp of the tooth).

Win stasis in that number if:

• non-foldable vision of one or more decal teeth;
• preparation of empty empty teeth before prosthetics.

Artikain in adrenaline with adrenaline knowlnly stasis in the offensive concentration:

• 1:200000;
• 1:100000.

Victory with muscle anesthetics with more adrenaline (1: 100000) means increased development of uncomfortable reactions in patients, which may cause pathology of periodontal tissue, as well as during the introduction of

Prototype

Buried vicoristannya of the anesthetizing motto Artikain in the offensive vipadki:

• in the presence of hypersensitivity reactions to articaine, adrenaline, sulfites, and also to any additional additional component, become a component of the drug;
• at different forms tachyarthymia, including paroxysmal cardiac arrhythmias;
• if there is evidence of bronchial asthma in anamnesis with overwhelming sensitivity to sulfites;
• with onyavn_y glaucoma zakrytokutov type;
• with one-hour therapy with non-selective beta-blockers (Propranolol, Timolol, Nadolol, Carvedilol);
• the deterioration of the liver function of a severe stage;
• excess hormone concentration thyroid gland in blood (hyperthyroidism);
• undergoing the course of therapy with drugs, such as monoamine oxidase (Selegilin, Perlindol, harmalin, Nialamid), or tricyclic antidepressants (Fluoxetine, Amitriptyline, Imipramine, trimipramine);
• with B12 deficiency anemia, methemoglominemia;
• with the presence of severe damage to the heart (bradycardia, atrioventricular block II-III stages);
• with the presence of illnesses of the central nervous system;
• in case of arterial hypertension bends;
• camp of hostile heart failure;
• great slit-face operative engagement, as well as surgical manipulation triviality of 20 khvili;
• children up to 4 rock_v.

To protect it from stopping:

• during the period of vagina;
• in breed with gestosis;
• if bleeding is evident in the last trimester of vaginosis;
• with non-stable blood cholesterol;
• with a lack of functionality;
• with the presence of diabetes mellitus;
• with hypertensive ailments.

How to save and add

The main feature of artikain is the building up to penetration into the tissue structure with the іn'ktsіy way of introduction. To that, the drug allows you to spend a lot of time (for example, preparation of teeth before prosthetics, operative soft fabrics, Visible teeth) for infiltrating anesthesia on the upper and lower cracks.

visibility side effects when carrying out the muscle method of pain in a large part, lay the required dose of the drug in the correct form, so that it can be used for anesthesia.

Especially a lot of respect comes to child dentistry, as it is explained by the small masa of the child, as well as by the peculiarities of the functions of organs and systems, as they take part in the children and the children of children, and so on.

The "golden" standard is the setting of the minimum amount of muscle anesthetic to achieve maximum control over the pain response. Also, the vibration of the connection is based on the penetration of the necessary protection and the hour of carrying out the necessary involvement.

4% Articaine with Adrenaline give a nadіynі znalyuyuyu dіyu, which manifests itself through 1-3 hilin іn'єktsії to the drug. The triviality of the game is 45-150 hvili. In this case, it means:

• good health penetration;
• good portability;
• minimal spasm of sudin;
• visibility arterial vise;
• the increase in the frequency of the heart is very fast;
• minimal penetration through the placental bar.

therapeutic dentistry

Stagnate Articulation in the designated dose will stagnate yak for infiltrating, so for it:

• preparation of carious empty;
• carrying out the treatment of pulpitis;
• carrying out therapy for periodontitis;
• carrying out operational involvement on periodontal disease.

For rejection of the sickness triviality from 30 to 45 chilines, the introduction from the outer (vestibular) side of the drug is administered at a dose of 0.5 to 1.8 ml per tooth.

surgical dentistry

Zastosovuyt іnstylyatsiyu lykarskogo zasobu in the pіdslizu area of ​​the required tooth in the total of 1.8 ml. If there is a need for additional medication, it is possible to administer the medication in the same way with the help of an additional antibiotic treatment. Vikoristovuyu for provincial and infiltrating anesthesia. Shown - a view of one or more dec_lkoh handrail of roztasvannyh teeth.

at promptly on the area of ​​the sky (overlapping seams, roses), there is a sufficient amount of the drug injected in the amount of 0.1 ml per injection.

Orthopedic dentistry

Vikoristovuyu for medical and medical anesthesia. Inject 0.5 to 1.8 ml s calling party cracks in the lining of the area of ​​the required tooth. If necessary, if necessary, it is possible to introduce no more than 7 mg per 1 kg of mass of a patient. Shown - carrying out odontopreparation.

Non-erection of the tooth, preparation before filling, preparation for setting the crown before the crown can be supressed from 0.5 to 1.8 ml of muscle anesthetic with a vasoconstrictor preparation (maximum 1 carpool). If the need for the introduction of articulation from the side of the patient, then vikoristovuyuyut 0.1 ml of microanesthesia.

The maximum dose that is permissible with the introduction of an articulation is:

• for a child from 4 to 12 rocks - 5 mg / kg;
• for children over 12 years old and older - 7 mg / kg.

Before the medication bezposredn_m, it is necessary to carry out an aspirate test, to remove the intravascular injection of the drug. The vice, wiggled on the piston for an hour after the introduction of the cloth, can be corrected in the form of sensitive fabrics. It is not recommended to introduce the drug into mucous dishes, which are signs of an ignition process.

Vicious Effects

Artikain can witness a number of unwelcoming effects:

• on the side of the nervous system: stupor, loss of svіdomosti, thrashing dyhannya, showing dyhannya, tremor, smacking of myase groups, generalized judgments, zamorochennya, cephalgia, hypesthesia (pain in the face, sensitiveness) paralich musculature of an individual);
• on the side of the organ zoru: impurity zoru, diplopia (double in the eyes), decrease in gosti zoru, slapota;
• from sides heart-vascular system: Reduced blood pressure, lack of heart function, cardiogenic shock;
• from sides herbal tract: blues nudity;
• from sides immune system: Reactions of hypersensitivity, in the mice of in'n'ktsii - functions of congestion, hyperemia, hyperemia of shkinny crooks, angioeurotic embryo (swelling of the upper and lower lip, cheeks, voices of sound)

Overdose

The introduction of an overwhelming dose to the drug can lead to developmental manifestations from the side of the other organ systems:

• Nervous system. I can be spared yak її driven, so і wake up. In the first vipadku sposterіgaut zamorochennya, zadishku, svіdomosti deterioration right up to the last time. Damage is characterized by tricky, causeless sickness, tremor of children, sudom, increased frequency dikhalnykh rukhiv, Adjusted the frequency of the heart is very fast.
• Sertsevo-sudinna system. ruin heart rhythm, Fibrillation of shlunochkiv, arterial hypotonia, heart disease.

• prinennya introduced to the drug;
• lay the patient on a horizontal surface;
• take care of the traffic dikhalnyh nobles, Infusion sour;
• control of the frequency of dichotomy and blood pressure;
• in case of ruined behavior - supply of sourness, intubation, piece ventilation lungs;
• in case of manifestation by the court - internally drive barbіturati of short triviality events (Cyclobarbital, Tiopental, hexobarbital, Kemіtal) with one-hour supply of sour and blood circulation control;
• in case of significant impairment of blood circulation and shock mills - internal infusion of electrolytes (Ringer, Aminol, Ringer-Locke), glucocorticosteroid hormones (Dexamethasone, Methylphenol) physiological breakdown, 5% glucose, coloids - dextran, starch, gelatin; Reopolyglyukin, blood plasma, Fluorodekalini), albumin;
• in case of colaptoid masses and bradycardia - more intravenous injection of 0.1 ml of adrenaline, droplets from the vein before the control of the arterial grip and frequency of the heart;
• in case of tachycardia and tachyarrhythmias - in the vein of beta-blockers (Metoprolol, Propranolol, Esmolol, Atenolol), blood pressure control and supply of sour.

lykarska vzaєmodiya

With a one-hour victorian artikaina z:

• with drugs that drive the nervous system (anesthetic drugs - Halothane, Ftorotan, snodiyni - Zopiklon, Zolpidem) help to make them stronger;
• anticoagulants (Heparin, Warfarin, Fraxiparin, Kleksan) by way of promoting the development of bleeding and bleeding;
• Ingibitors of monoamine oxidase (Selegelin, Pirlindol, Nialamid) promote the development of arterial hypotonia, it is shown that the intake of these drugs is shown for 10 dib before the planned dentistry;
• muscle relaxants (suxamethoniy, Tubocurarin, Orfenandrin, Dantrolene) are used to improve the triviality of the last lykarsky zasobiv;
• narcotic analgesics (Tramadol, Fentanil, Kodein, Buprenorphin) help to improve the improvement of the effective medications, as a result of the dysfunctional function;
• sudinozuzhuvalny drugs (Oxymetazoline, Xylometazoline, Kofein, Naphazolin) to accept and stimulate the muscular anesthetic effect of articaine;
• cholinesterase blockers (Neostigmin, Galantamin, Fizostigmin, Pyridostigmin), Tiotepa, Cyclophosphamide change the metabolic rate of articaine.

Articulation is the antagonist of lykarsky zasobiv, which is vikorystvuyutsya for lіkuvannya mіastheniya, for money on the transversely-dark muscles, especially when stuck in high doses, in the midst of the need for a lot of supplementation

When carrying out the processing of the miscellaneous anesthesia with deceptive problems, such as revealing important metal, the risk of development of an unpleasant miscellaneous reaction in the eye

special requests

When victorian artikainu slid dotrimuvatisya deyaki moments:

• vnutr_shnyovenna introduction is contraindicated;
• with the help of the prevention of infectious and ignition accelerated the steps for the sterility of the vikorovuvannyh heads and syringes when taking the drug from the ampoule;
• do not give a lower slit anesthesia for lower slit anesthesia and a weak child (in order to carry out the medical method of sickness);
• Infiltrating anesthesia injecting provincial painlessness in case of visible premolars of the lower slit;
• it is necessary to control the functions of the heart-vascular, nervous systems, respiratory tract;
• guilty, buty was carried out with the help of monoaminooxidases 10 dib before the introduction of the article.

Articulation for vaginosis and lactation

The stagnation of articulation in the period of vaginosti was not established due to the lack of a number of key donations. It is possible for the drug to be treated in the same way as the potential therapeutic effect is changing the potential risk of unpleasant inheritance for the fetus.

8650 0

Articaine
Group anesthetics group amidiv

Vipusku form

Mechanism of Diya

The penetration of the membrane for sodium ions is destroyed, and the conduction of the impulse along the nerve fiber is blocked.
Artikain rozshiryu sudini, and in dental practice it is important to use a vasoconstrictor (adrenaline hydrochloride 1: 100,000 or 1: 200,000).

Pharmacokinetics

Articain is good (up to 95%) to connect with blood plasmas, which reduces the ability to penetrate through the wall of the capillary into the tissue. Winnily penetrates through the placental bar, it is practical not to see breast milk. In patients with young anesthetics, there is the greatest plasma cleansing and shortest T1 / 2;

Є one of the most active and least toxic micevo-anesthetics, the most optimal in terms of activity and toxicity, the greatest breadth of therapeutic activity.

showing

How to store that dosi

Prototype

Guarding, monitoring therapy

All the solutions of articaine, to avenge the vasoconstrictors, to protect the endocrine disabilities(Heart defects, arterial hypertension, thyrotoxicosis, diabetes mellitus and in.), And also take in-adrenergic blockers, tricyclic antidepressants and MAOs.

If necessary, test articulation during the period of vaginosity, lactation, with heart-vascular insufficiency, diabetics, thyrotoxicosis LZ vibration є 4% of articaine with adrenaline 1: 200,000.

Vicious Effects

Overdose

Likuvannya: symptoms of the side of the central nervous system are deficient in barbiturates in a short period of time or tranquilizers in groups of benzodiazepines, for the correction of bradycardia and deterioration of adherence to adrenal hypertension, arterial hypertension

vzaєmodiya

Sinonymi

G.M. Barer, E.V. Zoryan

Articles: Instructions from Proceedings and Information

Latin name: Articaine

ATX code: N01BB08

Diyucha speech: articaine

Virobnik: Biohimik, VAT (Russia), Armavir bio-factory FKP (Russia)

Description and photo: 27.08.2019

Artikain is a non-barren insight, or with the help of an open mind for the inn'ktsiy.

Shown to zasosuvannya: Infiltration and Provincial Anesthesia in Dentistry. The drug is optimal for robots with patients with allergological anamnesis, in gerontological and child dentistry, in patients with heart-and-heart disease. An hour of sickness is from 1 to 3 hilin. An hour of effective anesthesia is not less than 20 minutes. You can prolong the anesthesia with the help of the addition of the anesthetic.

Analogue to the drug: Ultracaine D

Articaine muscle anesthetic(Looks like a doctor) for Infiltrating and Providing Anesthesia in Dentistry Practice, which can be affected by the disease. In tissues (in a weakly alkaline middle), hydrolysis and vivilnya base undergo hydrolysis and vividness, so that the lipophilic power and easily penetrate through the membrane in the middle of the nerve fiber.

articain in conjunction with receptors, blocking sodium channels in the membrane of the nerve fiber, inflating, in such a rank, muscle anesthesia.
Diya to the drug should be repaired quickly (latency period becomes 1-3 chilini). The triviality of the film is 20 khvili. Shvidke ruinuvannya articaine to an inactive metabolite - articainic acid - є the reason for this is very low toxicity, which allows reintroduction of the drug. Sour middle ground has the effect of lowering.

warehouse:

1 ml to the size:
active speech: articaine hydrochloride - 40 mg;
additional speech: sodium chloride - 2.1 mg
water for ін'єкцій up to 1 ml.

Instructions for storing

Before the introduction of the drug, it is recommended Always carry out an aspirating test to ensure that the intravascular injection of the drug is unified. The vice on the piston for an hour of the introduction of the drug is guilty of creeping in the presence of tissue sensitivity. It is not recommended to introduce the preparation into a fired slime bottle. Acceptance of this is only allowed by the renewal of sensitivity.

With unfolded visible teeth upper slit in the non-inflammatory stage - in the vestibular depot 1.7 ml per tooth; if necessary, additional - 1.0-1.7 ml.

For anesthesia in case of infantile problems and application of sutures from the stem of the pediatric depot - 0.1 ml.

With visible premolars of the lower slit(5-5) in the non-lethargic stage of anesthesia, there is an effect of provincial pain.

When preparing empty and chiselled teeth for a crown, For a vignette of molars of the lower slit, - vestibular ін'єкція 0.5 - 1.7 ml per tooth.

In case of a single medical procedure maximum dose for older adults - 4 mg / kg oil.

Stagnation during vaginosis and during lactation: The security of storing articulation for the hour of vaginosti has not been established due to the lack of key donations. Articaine penetrates through the placental bar'єr. Nutrition about drug intake by a dentist can be used only in the same way, as there is a potential for cinnamon in the form of a potency for the fetus. Do not have to pay for it (behind a vignette of powerful bradycardia) if there is any technique for storing that dose. During the period of lactation, there is no need to re-privatize the breast, so that clinically significant articulation concentrations do not appear in the breast milk.

Prototype indications:
Sensitivity has been adjusted to articulation, or to other local anesthetic drug groups
amidiv; megaloblastic B12 deficiency anemia; zakrytokutovaya glaucoma; falling ill of the central nervous system; chronic hypoxia; bronchial asthma.
Paroxysmalacardia; flashy tachyarrhythmia; severe damage to the heart (for example,
atrioventricular blockade II-III stage, bradycardia is rotated), heart failure, arterial hypotension.
O'єmni slit-face operations, as well as in case of triviality, the amount of money involved is 20 khviliin.
Childish up to 4 years old (efficiency and safety were not introduced).
For protection: Preeclampsia with preclamps, bleeding in the last trimester of vaginosis.

buy Artikain

Russia

Term of attachment: 3 rock

Artikain, razchin for ін'єкцій 40 mg / ml, ampoules 2 ml No. 10 price: 870,00 rubles. (pid replacement)

Articain 40 mg / ml, 1.7 ml cartridges No. 50 price: 1,430.00 rubles.

Articain with adrenaline (articain + adrenaline)

Artikain with adrenaline is a clear-cut insight, or with the most vidtіnkom razchin for in'uktsіy.

Shown to zasosuvannya: Infiltrating and providnikova anesthesia in dental operations - non-flattening of one or more deciduous teeth, emptying and grinding of teeth before prosthetics in adults and children older than 4 years. The drug can be vikoristovuvatisya in patients of a group of risik, in a child (in children older than 4 years), in the period of lactation. The hour of effective anesthesia should not be less than 45 minutes.

analogues:Ultracain DS, Ubistezin, septanest with adrenaline.

Articain with adrenaline- combinations of the drug, before the warehouse, which includes articaine (muscle anesthesia of the amid type) and adrenaline (subozuzhuvalny), which is delivered to the warehouse of the drug for prolongation of anesthesia.

Articain є local anesthetic, Zastosovvanim for Infiltration and Provider Anesthesia in dental practice. The structure of articaine is similar to those of the other micevo-anesthetics, but in its molecule there is one additional ether group, as it is in the body of humans that it is rapidly hydrolyzed by esterases. From the quick ruining of articaine to its inactive metabolite (articainic acid), there is already a low systemic toxicity, which allows the drug to be repeated.
Local anesthetic cushions wicked away the loss of sensitivity for the reduction of sensory nerve impulses in the vicinity of the message. The stench of membrane penetration will reduce the membrane penetration nerve cells for ions of sodium.

Articaine with adrenaline nadєshvidke (latency period - from 1 to 3 hilines) and stronger anesthetic effect and very good tissue tolerance.
The triviality of anesthesia should not be less than 45 min.
In addition, there is an even lower volume of adrenaline in the preparation of adrenaline, the inflow of the rest to the heart-vascular system does not change significantly: there is no increase in the arterial pressure and the increase in the frequency of heart speed.

Artikain z adrenaline warehouse:

1 ml to the size: diyuchі speeches: Articaine hydrochloride - 40 mg and adrenaline hydrotartrate - 0.009 mg (in case of pererakhunu for adrenaline - 0.005 mg, which responds to the change in adrenaline at a rate of 1: 200,000);

Articain with adrenaline

The drug has signs for storing in empty mouths and can only be introduced into fabrics, deceased. It is possible to carry out іn'єktsіyu in fired fabrics.
The drug cannot be administered internally.
For anesthesia in case of permanently visible teeth of the upper slit at a time of burning, there is a very sufficient stem of the depot articulation with adrenaline in the area of ​​the transitional fold by means of a pathway introduced into the pid-mucous membrane from the vestibular side (1.7 ml of the preparation per tooth). In rare cases, for additional general anesthesia, the introduction of 1 ml to 1.7 ml can be used. In most cases, it is permissible not to carry out painful mental illness. When you see the decal handrail, the teeth are rotated, a little of the inn'ktsiy bend into the casing.

For anesthesia in case of problems and application of sutures in the area of ​​childbirth From the stem of the pediatric depot, it is necessary to close 0.1 ml of the drug to the skin.

The most visible premolars of the lower slit at a time of burning, it is possible to do without mandibular anesthesia, so that you can get a sufficient infiltrating anesthesia, so that you get 1.7 ml per tooth. Even though such a way did not reach the bazhany effect, the Viconati Dodatkov inn'єktsiyu 1-1.7 ml of anesthetic in the pidlizovu shell in the middle of the transitional fold of the lower slit on the vestibular side. As long as the general anesthesia is not far away, it is necessary to conduct a provincial blockade of the inferior slit nerve.

When machining empty and machined teeth in front of the crown, Behind the vignette of the lower root teeth, in the fallowness as a rule and triviality, it is shown
the introduction of articaine with adrenaline in the area of ​​the transitional fold from the vestibular side at a dose of 0.5-1.7 ml per tooth.

We will grow up with a single dietary procedure Articaine can be administered in doses up to 7 mg per 1 kg of oil. Apparently, well, the patients tolerated the dose up to
500 mg.

For children of a child (over 4 years old) The dose of articulation with adrenaline is taken in the fallow area as a result of the viku and masi tila ditini, Alevona is not guilty
Perevischuvati 5 mg of articaine per 1 kg of oil.

The children of the kidnapped age and all the children with severe nirk and pechink deficiency More stemmed plasma concentrations of articaine. For a number of patients, the minimum dose is required to achieve a sufficient level of anesthesia.

Before the introduction of a double-stage aspiration test with a turn of the head by 90 and 180 (wonder at the detailed instructions).

Important systemic reactions in case of hateful intravascular injection of the drug can be done with a regular introduction: inject 0.1-0.2 ml of the drug at a time, then after 20-30 seconds, inject the drug into the solution. The vice of ін'єкції is guilty of giving the sensitiveness of the fabric.

Prototype indications: Hypersensitivity to articulation, but to some of the anti-anesthetizing problems of the amid type, in case of a hypersensitivity to the hypersensitivity to the anti-anesthetics of the amid type of allergy to the articular type of allergy Hypersensitivity to adrenaline; hypersensitivity to any additional components in the drug. (Marvel at the detailed instructions).

Buy Artikain with adrenaline (Artikain + adrenaline)

Virobnik: ZAT "Binergia", Russia

Term of attachment: 2.5 rock cartridges, 3 rock ampoules

Articain with adrenaline, rozchin for іn'єktsіy (40 mg + 0.005 mg) / ml, ampoules 2 ml No. 10 price: 870.00 rubles. (pid replacement)

Articain with adrenaline 40 + 0.005 mg / ml cartridges (1: 200 000) 1.7 ml No. 50 price: 1 350,00 rubles.

Articaine with adrenaline fort

Artikain s adrenaline fort is an insight without barriers, or zhovtuvatim vіdtіnkom razchin for ін'єкцій.

Shown to zasosuvannya: Infiltrating anesthesia on the upper slit and in the anterior slit (including the premolar) of the lower slit, provincial anesthesia. The drug of indications for muscle anesthesia (infiltrating and providnikova anesthesia) in dentistry in case of traumatic involvement and in case of need for hemostasis, or polyphenomenon of the operative field. The hour of effective anesthesia should not be less than 75 hilines.

analogues: Ultracain DS forte, Ubistezin forte, septanest with adrenaline.

Registration number: ЛСР-008523/10

Trade name of the drug: Articaine with adrenaline forte

Grouping names: Artikain + [Epinephrine]

Likarska form: rozchin for ін'єкцій

warehouse

1 ml.

active speech: articain hydrochloride (per 100% adrenaline) - 40 mg and adrenaline hydrotartrate (per 100% adrenaline) - 0.018 mg (per adrenal perennial - 0.010 mg, which results in 100% adrenaline) ;

additional speech: sodium disulfite - 0.50 mg, sodium chloride - 1.00 mg, water for ін'єкцій up to 1 ml.

to describe

The insight is without bargaining, or with the zhovtuvatim vіdtіnkom razchin.

Pharmacotherapeutic group

Micevo-anesthetic susceptibility + alpha-and-beta-adrenergic agonist.

ATX code: N01BB58

Pharmacological authorities

Pharmacodynamics

• Articaine with adrenaline forte, stasis for infiltrating and provincial anesthesia in dentistry, є combined drug Before the warehouse, which includes articaine (muscle-anesthetic, amic type) and adrenaline (subozuzhuvalny), which is used to supply the drug for prolongation of anesthesia to the warehouse.
• Articaine nadaє muscular anesthesia for the blockage of potential-depleted sodium channels in the cell membranes of neurons, so that the conduction of the impulses through the nerve fiber and the circulating power is brought to a reverse drive.
• Articaine with adrenaline forte to repair shvidka (latency period - from 1 to 3 min) and stronger anesthetic effect and good tissue tolerance. triviality
• effective anesthesia, incl. intrapulpal, to become not less than 75 quills, the triviality of anesthesia of soft tissues - from 120 to 240 quills.

• Previously published reports showed that in children from 3.5 to 16 years of age, the drug in a dose of 7 mg articaine per 1 kg The triviality of anesthesia was porous in all groups and was based on the amount of drug administered.

Pharmacokinetics

• The ligation of articaine with blood plasmas becomes approximately 95%. When introduced into the empty mouth, the period of articaine intake becomes 25.3 ± 3.3 min. Articulation quickly and practically immediately after the introduction is metabolized by way of hydrolysis by nonspecific plasma esterases of blood and tissues (90%). Up to 10% of articaine is metabolized in the oven. At the same time, the head metabolism of articaine - articainic acid - does not volodyne anesthetic activity and systemic toxicity, but allows the reintroduction of the drug. Articain is vivodied with nirkami, the head rank, in the viglyadi of articainic acid.
• In children, infusion during infiltrating anesthesia from the vestibular side can be infused in older adults, the maximum concentration of articain in blood plasma can be reached more quickly.

Shown to sucking

Lykarsky drug Artikain with adrenal forte indications for muscle anesthesia (infiltration and provincial anesthesia) in dentistry in case of traumatic interventions and in case of need for abnormal hemostasis or surgery

• stomatologic operations on mucous membranes or cysts, which help to increase the level of minds with a larger circulation;
• surgery on the pulp of the tooth (amputation or extirpation);
• the vision of an evil tooth (osteotomy) or a tooth affected by apical periodontitis;
• trivial surgery;
• through osteosynthesis;
• excision of kist;
• involved in sliz_y obolonts_ is clear;
• resection of the top of the root of the tooth.

Prototype

Sensitivity has been adjusted to articulation, or to other micevo-anesthetics of the amid type, epinephrine, sulfites (zokrema, in patients who are bronchial asthma I am sensitive to sulfites, so as there are possible severe allergic reactions with symptoms of anaphylactic shock, such as bronchospasm), or even before any additional components in the drug.

Prototype indication in connection with the presence of articaine at the warehouse

Severe damage to the function sinus node any severe deterioration of conductivity (for example, bradycardia, atrioventricular block II or III stage);

Gostra decompensated heart failure;

An important form of arterial hypotension;

Childish up to 4 years Prototype indication in connection with the presence of the drug epinephrine at the warehouse

Zakritokutov glaucoma;

Hyperfunction of the thyroid gland;

Paroxysmal cardiac, tachyarrhythmia;

Not long ago transfers of myocardial infarction (up to 6 months);

Not long ago postponed coronary artery bypass surgery (up to 3 months);

Acceptance of non-selective beta-blockers, for example, propranolol (risk of hypertensive crisis and important form of bradycardia);

pheochromocytoma;

important form arterial hypertension... With protection

In patients with chronic heart failure, ischemic ailment heart, angina pectoris, atherosclerosis, history of myocardial infarction, impaired heart rhythm, arterial hypertension;

Patients with cerebrovascular lesions, history of stroke;

At the children chronic bronchitis, Emphіzemoyu legends;

At the children for diabet(Potential risk of changes in the concentration of glucose in the blood);

In patients with a lack of cholinesterase (it is more likely to be deprived of it in times of extreme need, as it can be prolonged and not beaten by the drug);

Patients with broken bloodshed;

Patients with severely damaged liver function and nirok;

For patients with rotational damages;

Patients with epilepsy in anamnesis;

In case of sleeping with halogen-containing substances during the ingestion anesthesia (div. Rozdil lykarskiy zasobami"). Stagnation during vaginosis and during breastfeeding

availability

Articain and adrenaline penetrate through the placental bar.

The concentration of articaine in the blood of newborns (when the drug is administered to the mother) becomes approximately 30% of the concentration of articaine in the blood of the mother. I will look at the lack of clinical tributes, the decision about the use of the drug by the dentist can be taken only in the same way, since there is a potential shortage of this drug for the mother. If necessary, consuming articulation for an hour of vaginosity is more effective than consuming medications, but not taking adrenaline but with a concentration of 0.005 mg / ml adrenaline.

With vipadkovy intravascular injected adrenaline can change the blood flow of the uterus. Period of breastfeeding

With a short-line drug during the period of breastfeeding, as a rule, it is not necessary to interrupt the breastfeeding period, so it does not appear in breast milk clinically

significant concentrations of articaine and adrenaline.

Fertility

Experimental dosage of articulation 40 mg / ml + adrenaline 0.01 mg / ml on animals did not show an influx on fertility in individuals of cholovic and female statics. When the drug is consumed in therapeutic doses, negative injection of the drug on the fertility of people during the day. How to store that dosi

The drug can be administered only in non-burning tissue.

The drug is not allowed to be administered internally!

A drug of signs for storing in mouth emptying.

In order to unicuti the vapadic drug consumption in the blood vessels, before the introduction of the drug, it is necessary to carry out a two-stage aspiration test with the head turning 90 and 180 °. The main systemic reactions, which may develop as a result of a vague intravascular injection of the drug, can be unique, if the technology is used: when an aspirate test is carried out, inject 0.1 - on a daily basis to inject a dose of the drug. The vice of ін'єкції is guilty of giving the sensitiveness of the fabric.

In order to prevent infection (including hepatitis virus), it is necessary to keep an eye on the patient, when taking the drug from the ampoules, new sterile syringes and heads were used. It is not possible to see the cartridges again for other patients (not without hepatitis)! It is not possible to pick up single cartridges.

Likarskiy zasіb not slіd zastosovuvati, as soon as he changes his color, for becoming kalamutny. dosage regimen

For anesthesia in case of non-folded visible teeth of the upper slit during the day, the depot depot preparation Articain with adrenal forte in the region is quite sufficient.

a transitional fold with a path of its introduction into the pid-mucosa from the vestibular side (1.7 ml of the preparation per tooth). You can be familiar with any additional anesthesia

dodatkove introduction from 1 ml to 1.7 ml. In most cases, it is permissible not to carry out painful mental illness.

For anesthesia in cases of development and application of sutures in the area of ​​the palate with the opening of the pediatric depot, approximately 0.1 ml of the drug is needed per injection.

When you see the decal handrail, the teeth are rotated, a little of the inn'ktsiy bend into the casing.

In the case of visible premolars of the lower slit at the time of burning, as a rule, add 1.7 ml of the preparation per tooth. Well, such a path did not reach the bazhany

efectu, slid vikonati dodatkova іn'єktsіyu 1 - 1.7 ml of anesthetic in the pid-mucous membrane in the area of ​​the transitional fold of the lower slit on the vestibular side.

As long as the general anesthesia is not far away, it is necessary to conduct a provincial blockade of the inferior slit nerve.

at surgical procedures In cases of heavy and triviality, the drug Articaine with adrenaline forte is administered individually.

With a single treatment procedure, adults can be administered up to 7 mg of articaine per 1 kg of oil. Apparently, the patients tolerated doses up to 500 mg (12.5 ml of the drug).

Patients of a kidnapped vik and a child with a severe nirk and pechinka deficiency

The patients of the kidnapped person and all the patients with severe nirkovy and pechinka deficiencies have more advanced plasma concentrations of articaine. For qich

Patients with the lowest dose required to achieve adequate anesthesia.

• For patients of a childish age (older than 4 years), a minimum dose is required to achieve adequate anesthesia. The dose of the drug Articaine with adrenaline forte is picked up in the fallow area as a result of the disease, and Alevona is not guilty of replacing 7 mg of articaine per 1 kg of body weight (0.175 ml / kg). Zastosuvannya drug in children up to 1 fate was not implanted. Pobichna diya
• The frequency of development of side effects is presented according to the classification recommended by the All-Holy Organization of Health Protection: even more often (2 1/10); often (2 1/100,< 1/10); нечасто (2 1/1000, < 1/100); редко (2 1/10000, < 1/1000); очень редко (< 1/10000), включая отдельные сообщения; частота неизвестна (не может быть определена по имеющимся данным). Нарушения со стороны иммунной системы Частота неизвестна
• Allergic or allergic reactions. You can turn around at the viewer and (or) burned in the picture, itching, Conjunctivitis, rhinitis, angioeurotic denunciation of the upper and (or) lower lip, the larynx, the larynx from the sight of the "breast in the throat"
• On the side of the central nervous systems / Often

Paresthesia, hypesthesia, head b_l(Due to the presence of epinephrine in the warehouse).

Zamorochennya.

incidence of abnormalities

Dose-related reactions from the side of the central nervous system (including at extremely high doses, for example, in case of severe internal vascular disease): symptoms of anxiety, nervousness, stupor, loss of pain in the home tremor and smacking of muses right up to generalized by the court;

when damaged correct technique the introduction of the drug for any anatomical peculiarities in the area of ​​the facial nerve can lead to a paralysis of the facial nerve and a decrease in sensory impressions.

Damage from the side to the organ of the zoru

incidence of abnormalities

Good health (uncleanness of healthy sleepiness, medriasis, sleepiness, twins in the eyes), as a rule, werewolves and come out for an hour, or after a short hour, when you get an anesthetized cat.

Articain with adrenaline forte, rozchin for ін'єкцій (40 mg + 0.01 mg) / ml, ampoules 2 ml No. 10 price: 870,00 rubles. (pid replacement)

Articaine with adrenaline forte 40 + 0.01 mg / ml cartridges (1: 100,000) 1.7 ml No. 50 price: 1,430.00 rubles.

We give the goods also to bathe:

• Articaine, Articaine with adrenaline, Articaine with adrenaline forte

Gross formula

Pharmacological group of speech Artikain

Nosological classification (ICD-10)

CAS code

Characteristics of the speech of Artikain

Micevial ​​anesthetic from the group of amidiv.

Bіliy or bіliy s creamy crystalline powder. Razchinniy in water and alcohol.

pharmacology

In tissues (in a slightly alkaline middle), there is a hydrolysis and a strong base, but the lipophilic power and easily penetrate through the membrane in the middle of the nerve fiber. Ionize (through a higher low pH) and transform into cation. In connection with receptors, the input of sodium ions into the cellin in the phase of depolarization and blocking of the impulse along the nerve fiber.

With i / m introduced C max, it can be reached after 20-40 minutes. T 1/2 - close to 40 min. In case of infiltrating anesthesia in an empty company, it is very diffuse. Biotransform in the oven. Penetrating through the placental bar, in insignificant quantities it penetrates through the hematoencephalic bar, it is practically impossible to see breast milk. Vivoditsya nirkami (54-63% in 6 years). The triviality of anesthesia is 60 and 180 mins when vasoconstrictors are added. Sour middle ground has the effect of lowering.

Zasosuvannya speech Artikain

Infiltration and provincial anesthesia, incl. in dental operations: uncomplicated visualization of one or more decal teeth, processing of carious empty teeth and grinding of teeth before prosthetics.

Prototype

Hypersensitivity to articular disease, local anesthetics of LZ groups of amids, as well as to sulfites (especially in patients with bronchial asthma), anemia (including B 12-deficit anemia), paroxysmal tachycardia (such as bradycardia, stage II-III AV blockade), heart failure, severe arterial hypotension, glaucoma, methemoglobinemia, hypoxia, childish vik up to 4 rockets (safety and efficiency of money supply).

Stagnation during vaginosis and breastfeeding

Do not have to pay for it (behind a vignette of powerful bradycardia) if there is any technique for storing that dosuvanny.

actualization of information

Articaine penetrates through the placental bar'єr. I will look at the lack of clinical data, the decision about the appointment of an article by a doctor-dentist can be taken only in the same way, since there is a potential shortage from this stagnation of a truly potential risk for the fetus.
During the period of lactation, there is no need to re-privatize breast year bath Therefore, clinically significant concentrations of articaine do not appear in breast milk, as a substitute for the protection of the breast, it should be taken for 4 years after the introduction of the last dose of articaine.

[Updated 14.03.2013 ]

Pobichni diya speeches Artikain

On the side of the nervous system that organs are sensitive: headache, zapamorochennya, damaged svidomostі (right up to the last), muscular tremor and smacking of muses (up to generalized by the court), dim in the eyes, diplopia.

On the side of the cardiovascular system and blood (blood formation, hemostasis): lowering the arterial grip, zupinka heart.

On the side of the organs in the shlunkovo-intestinal tract: nudity blues.

Three sides respiratory system: ruin dikhannya (right up to yaka will load the life zupinki).

Allergic reactions: sverbіzh, cropping, hyperaemia, conjunctivitis, rhinitis, angioedema, anaphylactic shock.

Інші: mіsceі reactions

vzaєmodiya

The effect of articaine podsilyut and podovzhuyut vasoconstructions.

actualization of information

Local anesthetics can be used to adapt to LZ, to adjust the central nervous system. Narcotic analgesics will increase the frequency of anesthetics and increase the risk of impairing symptoms.
When carrying out an articaine test for patients who take heparin or acetylsalicylic acid, Mossy development is bleeding in mісtsі ін'єкції.
With a one-hour consumption of articulation and muscle relaxants, the strength and growth of muscle relaxants is possible.
Articaine exhibits antagonism to the skeletal muscles of the antimyasthenic LZ, especially when it is consumed in high doses, as well as a pre-treatment correction of myasthenia.
With a one-hour consumption of articaine with cholinesterase inhibitors, it is possible to increase the metabolism of articaine.

Dzherelo information

grls.rosminzdrav.ru

[Updated 06.05.2013 ]

Overdose

symptoms: zapamorochennya, rukhove zbudzhennya, loss of evidence, reduction of arterial vise, tachycardia / bradycardia.

lykuvannya: when the first signs of an overdose appear, it is necessary to apply the drug to the sick person horizontal position, Prevent the free passage of the wiry paths, control the heart rate and AT. When bad, apnea - muslin, endotracheal intubation, piece ventilation of legends (central analeptics of contraindications); in case of sudomas - in / in the general introduction of barbіturatіv of a short period with one-hour іngalyatsієyu sisnyu and control of hemodynamics; in case of severe impairment of blood circulation and shock - intravenous infusion of electrolytes and plasma monitors, GC, albumin; in case of convulsive collapse and acute bradycardia - intravenous injection of adrenaline 0.1 mg (dal - intravenous drip under the control of heart rate and AT). Oxygen therapy and blood circulation control is necessary for all types of patients.