Mycosyst іnstruktsіya іf storing, prototypes, failures, advice. Yak correctly vikoristovuvati drug Mikosist from a fungus? Injection Mikosist on organism side effect

Instructions for storing:

Mikosist - lykarskiy zasіb with anti-fungal dієu.

Form vipusk and warehouse

Mikosist vipuska in two lykarsky forms Oh:

Rozchin for infusion prozorium, without barn or trochas of infusions (100 ml in vials, 1 vial in cardboard pouch);
Capsules: solid, gelatinous, impenetrable with a large body (L500), filled with a powder or white color for a powder-like solid mass; 50 mg each - size No. 4, light-blue opaque krishechkoy (L910) (7 pcs. in blisters, 1 blister in a cardboard patch); 100 mg each - size No. 2, with bryuzovy opaque krishechkoy (L890) (7 pcs. in blisters, 1 or 4 blisters in cardboard pouch); 150 mg each - size No. 1, with blue opaque krishechka (L860) (1 pc. in blisters, 1, 2 or 4 blisters in cardboard pouch).

Up to 1 capsule warehouse include:

Speech is active: fluconazole - 50/100/150 mg;
Additional components (capsules of 50/100/150 mg each): magnesium stearate - 1.2 / 2.4 / 3.6 mg, povidone - 3.6 / 7.2 / 10.8 mg, anhydrous lactose - 49, 5/99 / 148.5 mg, corn starch - 12.1 / 24.2 / 36.3 mg, talc - 3.3 / 6.6 / 9.9 mg, coloidal silicon dioxide - 0.3 / 0, 6 / 0.9 mg;
Krishechka (capsules of 50/100/150 mg separately): titanium dioxide (E171, CI77891) - 4/4 / 1.5%, indigocarmin (E132, CI73015) - 0.0086 / 0.0471 / 0.2513%, gelatin - up to 100% (for all types of capsules);
Body (capsules of 50/100/150 mg each): titanium dioxide (E171, C.I. 77891) - 2/2/2%, gelatin - up to 100% (for all types of capsules).

To the warehouse of 10 ml, the size for infusions should be included:

Speech is active: fluconazole - 20 mg;
Additional components: sodium chloride - 90 mg, water for ін'єкцій - up to 10 ml.

Shown to sucking

Generalization of candidiasis: candidiasis, disseminations of candidiasis and other forms of invasive candidiasis infections (infections of the eyes, endocardium, black empty, Sechovividnykh i dikhalnyh nobles), In addition, in patients who receive a course of cytostatic or immunosuppressive therapy, as well as, if any of these factors are present, they can develop candidiasis (with a beneficial and preventive treatment);
Cryptococosis: cryptococcal infections of children and legends, cryptococcal sepsis and meningitis, cryptococosis in case of syndrome of accumulated immunodeficiency (with the help of prevention of recurrence); in case of organ transplantation in cases of immunodeficiency;
Candidiasis of mucous membranes, incl. candidiasis of the stravohode, pharynx, empty mouth (including dressings on the nose of dentures, atrophic candidiasis), as well as candidiasis, non-invasive broncholegenic infections;
Genital candidiasis: vaginal (chronic relapsing abo gostra uniform); candidiasis balanitis (capsules);
Fungal infections in ailments evil new creatures, Shilnyh to the development of such infections through chemotherapy with cytostatics or exchange therapy; oropharyngial candidiasis in patients with SNIDom (with the help of prophylaxis);
Mykozy shkiri, including mykozy groin area and tuluba;
Gliboki endemic mycoses, including coccidioidosis, histoplasmosis and paracoccidioidosis in ailments with normal immunity;
Onikhomykoz, mykozy feet, viscous versicolor (capsules).

Prototype

absolute:

Lactose intolerance, lactase deficiency, glucose-galactose malabsorption;
Immediately consumed with terfenadine (in case of continuous intake of Mycosyst in an additional dose of 400 mg), cisapride (preparations are used to drink an increase in the risk of important breakdowns in the heart rhythm and an increase in the QT interval);
Immediately zastosuvannya with astemizole;
period thoracic treatment;
Hypersensitivity to the components of the preparation, or to those close to the structure of azole spolucs.

Vidnosnі (Mycosist needs to be secured with protection for such incapacitation / mills):

Pechinkova / abo nirkova lack;
Visip when taking the drug in ailments with systemic and / or invasive fungal infections and superficial fungal infections;
Potentially proarrhythmogenic become in ailments with many factors of risk, including damage electrolyte balance, Organic ailments of the heart, immediately consumed with zuhvali arrhythmias drugs;
intolerance acetylsalicylic acid;
One hour consumption of terfenadine (with an additional dose of fluconazole up to 400 mg);
Immediately stagnant with rifabutin or other lykarsky substances, which metabolize due to the participation of the cytochrome P450 system;
Viability.

How to save and add

Inject mycosyst at viglyadia for infusions internally in drops with no more than 20 mg (10 ml) in 1 quiline; take the capsules in the middle.

Koriguvati dobovi dozi when passing from one lykarskoy form to іnshu didn’t go.

Dissemination of candidiasis, candidiasis and invasive infections, infections with Candida fungi: on the first day - in an additional dose of 400 mg, dal - 200 mg per day. In case of need, the dose is increased by 2 times, with important systemic candidiasis - up to 800 mg per day. The triviality of the course is to lay down due to the clinical effectiveness of the drug, with the growth of Mycosist, it is necessary to continue for at least 14 days to develop the symptoms of ailments, or in case of confirmed negative hemoculture;
Cryptococcal infections: on the first day - in an additional dose of 400 mg, dal - once a day, 200-400 mg. The triviality of the course will be confirmed by the results of the microscopic advances in clinical effectiveness. Most often therapy is carried out from 6 days to 2 months. With the treatment of cryptococcal meningitis, a greater triviality of Mikosist is shown - from 10 months to 2 months for a negative result of microbiological pre-test spinal cord... By the end main course the first therapy with the method of prevention of relapse of cryptococcal meningitis is ailment with SNIDom, it is recommended to trivially consume Mikosist at 200 mg per day;
Atrophic candidiasis of empty mouth, dressings with dentures: 14 days at an additional dose of 50 mg. Therapy followed by the use of antiseptic materials for cleaning the prosthesis;
Oropharyngeal candidiasis, including patients with impaired immunity: 7-14 days for an additional dose of 50-100 mg. For prophylaxis for patients with SNIDOM, after completing the main course of primary therapy, Mikosist is prescribed 150 mg 1 time in 7 days. If necessary (especially in case of severe damage to immunity), the triviality of the disease is increased;
Secondary candidiasis infections (candidiasis, esophagitis, non-invasive broncholegenic infections, candidiasis of shkiri and mucous membranes): 14-30 days at an additional dose of 50-100 mg;
Vaginal candidiasis: one-time 150 mg. To reduce the frequency of recurrences Mycosyst in the same dose should be taken 1 time per month for 4-12 months, in some cases more often it is consumed;
Important candidiasis of mucous membranes: 100-200 mg per doba;
Balanitis, Candida spp.: One-time 150 mg of Mycosist in capsule form;
Prevention of candidiasis: dobova dose it starts with the development of fungal infections, and can vary between 50 and 400 mg. When explicit high rhiziku generalized infections (for example, patients with a pre-treatment or a neu- tropenia) Mycosist is prescribed 400 mg per day. The drug needs to be repaired for a few days until the development of neutropenia is cleared, if the number of neutrophils increases over 1000 / mm ³ the therapy lasts for 7 days;
Fungal infections in ailments with malignant neoplasms (prophylaxis): the drug at an additional dose of 50 mg must be taken up to quiet feasts, since the ailments are in the group of advanced industrial therapy in the case of cytostatic diseases;
Viscous lichen: 2 doses of 300 mg of Mycosist in capsule form with a break of 7 days. In some cases, you can take the third dose - 300 mg from the same dose, but it is not easy to take a single dose of 300 mg. In an alternative dosing regimen, a potent intake of 50 mg of Mycosist per day for 2 months up to 1 month;
Mykozy shkiri (including candidiasis), including mycozy groin area, feet: 50 mg per day or once every 7 days, 150 mg of the drug in capsule form. As a rule, the triviality of therapy varies between 7-14 days;
Gliboki endemic mycozy: 200-400 mg per day for 2 rockyv. The triviality of the therapeutic course begins individually: paracoccidioidosis - 2-17 months, coccidioidosis - 11-24 months, histoplasmosis - 3-17 months;
Onichomycosis: 150 mg of Mycosyst in capsule form 1 time in 7 days. Taking the drug requires prodovzhuvati until a quiet feast, as long as he is healthy, it will not replace the information on the rise. Most often, for repeated growth of nigtіv on the fingers and nіg prodovzhuvati with the drug, it is necessary to stretch out from 3 to 6 and from 6 to 12 months as appropriate.

For children, the triviality of therapy is based on a clinical and a microchological effect. Dobova dose for the whole category of ailments is not guilty of changing taku among grown-ups. Mikosist slid zastosovuvati once a day.

Cryptococcal infections and generalizations of candidiasis: 6-12 mg / kg per day (if there is a severe ailment);
Candidiasis of mucous membranes: 3 mg / kg per day. It is allowed to sign the shock dose of Mikosist (2 times more zvychaynoi) on the first day of treatment;
Fungal infections in children with reduced immunity, in some patients, in patients with diseases of the disease with neutropenia, as a result of cytotoxic chemotherapy and neutrophilization therapy: ).

In newborns, fluconazole is more commonly used, for that in the first 14 days of life, Mycosyst needs to be taken in the same dose (in mg per 1 kg of body weight), and in older children who have taken the preparation for 72 For children 3-4 years old, the drug is prescribed for 48 years of interruption.

Patients of a kidnapped person with functional impairments do not need a correction to the Mikosist dosage regimen.

we are sick nirk deficiency in case of a one-time consumption of the drug, a dose correction is not required. In case of a course designation, the dose rate should be taken (from 50 to 400 mg);

Clearance to creatine more than 50 ml per quiline: 100% of the recommended (usually indicated) dose;
Clearance to creatine less than 50 ml per quiline (without dialysis): 50% of the recommended dose.

To be found on a regular treatment by the method of dialysis, we are sick for a skin session to indicate 100% of the recommended dose.

Roschin for infusion sums with the solution of sodium chloride, sodium bicarbonate (0.9%), calcium chloride in glucose, Hartman, Ringer's products and 20% glucose solution. Infusion of fluconazole can be carried out on the basis of one of the recipients of the transfusion set for additional transfusion sets.

Pobichna diya

In case of stagnation of Mycosyst, damage can develop from the side of some systems to the body:

Nervous system: zapamorochennya, sudomi, head b_l;
Herbal system: abdominal pain, diarrhea, flatulence, impaired liver function (hepatocellular necrosis, including with a lethal result, zhovtyanitsya, hepatitis, hyperbilirubinemia, altered activity, smudge phosphatase), transmucosal
Heart-and-heart system: triplet and / or even less shlunochkiv, increase on the electrocardiogram of the triviality of the QT interval;
Rechovin exchange: hypertriglyceridemia, hypocalypsemia, hypercholesterolemia;
Organ blood formation: agranulocytosis, thrombocytopenia, neutropenia, leukopenia;
Allergic reactions: multiforme erythema (including Stevens-Johnson syndrome), bronchial asthma(In most cases, with intolerance to acetylsalicylic acid), anaphylactic reactions (including swelling of accusation, sverbіzh shkіri, kropivyanka, angioedema viscera), Lyrniyll's syndrome, scabies;
Іnshi: alopecia, functional breakdown nirok.

special requests

It is necessary to carry out the treatment before the appearance of clinical and hematological remission, some of the early recovery of Mikosist's disease can lead to the development of relapses.

Fluconazole supplementation has been shown to be evident in children with severe symptoms. toxic on the liver (including a fatal result), most often - in ailments with serious concomitant ailments. At the connection from the time of the preparation of Mikosist, it is necessary to control the function of the liver, and when there is a sign of a fight, which can be tied with the drug, the therapy is followed by skasuvati.

Every hour of treatment, in some cases, indicated the development of extreme school reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis). Greater mental health until the development of grave childish reactions of ailment from evil new solutions and SNID.

If during the period of treatment in ailments with a superficial fungal infection, it is difficult to diagnose a disease, since it is possible to tie it with a Mikosist's pod, therapy is required for scasuvati. Particularly, retinal control in case of diagnosed visipu is required for patients with systemic invasive fungal infections.

When developing a multiforme erythemi abo bully urazhen, the drug is taken.

With one-hour therapy with indirect anticoagulants of the coumarin series, it is recommended to control the prothrombin hour.

Oskilki Mykosist can be damaged, for an hour we are sick, we need to take care of the safety when we see potentially not safe types of robots, as they require smart psychomotor reactions and respect to traffic.

likarska vzaєmodiya

With a one-hour consumption of Mycosyst with some kind of lykarsky zasob, there may be such effects (T 1/2 - the period of the speech; C max - the maximum concentration of the drug in the blood):

Zidovudine: increased concentration in blood plasma and increased development of side effects;
Sulfonylsecovine preparations: increased T 1/2, in conjunction with such combination of symptoms, it is necessary to determine the possibility of diagnosing hypoglycemia;
Tacrolimus: the adjustment of the concentration in the blood and the development of nephrotoxicity;
Teofilin: lowering the average efficiency of the blood plasma, increasing the risk of developing this toxic effect and overdosing;
Phenytoin: it is clinically more important than the adjustment of the concentration (you can know the correction of the dose);
Rifampicin: decrease in C max and T 1/2 (correction of dose of fluconazole may be necessary);
Midazolam: the value of increasing the concentration in blood plasma and the development of psychomotor reactions;
Rifabutin: increasing the level of concentration, increasing the level of development;
Cyclosporine: increased blood concentration;
Hydrochlorothiazide: adjusting the concentration of fluconazole in blood plasma.

With a one-hour consumption of Mycosyst with other drugs, they are metabolized by the cytochrome P450 system, it is necessary to take care of it.

analogs

Analogues of Mikosist є: Diflucan, Medoflucon, Mikoflucan, Mikomax, Flucostat, Fluconazole, Fluconazole-Teva, Flucorus, Flucomabol, Flucosan.

Terms and conditions

Keep out of reach of children at temperatures up to 30 ° C.

Term of attachment:

Rozchin for infusions - 2 rock;
Capsules - 5 rock.

Mind that term zberigannya

Capsules are available without a prescription, solutions for infusions are available for a prescription.

Mikosist - lykarsky drug, signs for the treatment of fungal diseases of the nature. It is highly effective against other fungi, other fungi and trichophytosis. The robot is active for the drug to take care of the rakhunok diyuchy speech- fluconazole. Fluconazole є is synthesized for the purpose of entering the group of triazole fluids. Wine is tough, selective and overwhelming. With this help, there is a zupinity of fermenting enzymes, so that it can prevent the growth of pathogenic microorganisms. With a lot of active speech, it is possible to catch the fungal infection, which is not infused with it on the person.

Vipusku form

Form a vipusk drug

On the current day, Mikosist can be used for two likarski forms: capsules and solutions for internal introduction. All the stinks may be similar to those shown for the reception. By the active speech of the danikhs є fluconazole, the effectiveness of which is promoted by the actions of ancillary Ingredients. Capsules Mikosist are dispensed in 3 doses: 50, 100 and 150 mg of fluconazole. Diznatysya, scho you buy it, is even simpler: just look at the name. Vyrobnik will add a bit of dialectic speech on pachtsi. Rozchin Mikosist is released in doses of 1 or 2 ml.

Fakhivtsi mean, for those who get sick most often capsules are given to doses of 150 ml. Smell volodyut as a result and a minimum side-by-side... It is necessary to vrahovuvati, so Mikosist is not a pill, but a capsule. Most often it is recognized in the fight against thrush. Likas are not allowed in the form of suppositories, the virobnik is not in use with the gel.

warehouse

Mikogsist packaging

Warehouse Mikosyst has been developed for the specific features of fungal organisms. It is efficient to cope with any kinds of plants. An important component in this drug is fluconazole. I myself will take care of anti-firing, anti-fungal, immunomodulatory deities. Regular stagnation is possible to reduce the reduction of the organism's capacity to pathogenic discourses. At the warehouse, there are the following components:

Silicon dioxide - increases the moisture content of the active components of the lykarsky plant;
Titanium dioxide - approved for the prevention of the scorching of the shlunkovannya glass;
Corn starch - stored space in capsules;
Gelatin - based on the integrity of the capsule;
Lactose is a prey organism in the form of allergic reactions;
Indigokarmin - fill the tablets in the colir.

Warehouse razchinu Mikosist for ін'єкцій більш poor. Winnings for a single dose of fluconazole, purification water, new drugs and sodium chloride. With the actions of the organisms, the victoriousness of such a lykarskoy form is more true.

Should it be recognized?

Mycosyst is an anti-cotic zasib, which is a kind of building stifle to stifle the activity of such kind of animals. Before zasosuvannyam, learn about the instructions, in which it is meant, if the most beautifully victorious daniyas. Name the tablets and it is recognized for:

Candidiasis of mucous membranes or candidiasis;
Generalized candidiasis, infectious internal organsі systems;
For an hour cytostatic or immunosuppressive therapy;
For the prevention of recurrent mycosis aggravation;
Cryptococcal infected organisms;
Fungal lesions, internal organs;
Transplantation of organs for infection;
Bronchogenic infections;
Genital candidiasis, vicious with other fungi;
Fungal infections in patients who suffer from puffy new solutions for the hour of chemotherapy;
Mycoses tuluba and groin;
fungal infection nigtyovyh plates;
Lisha;
Endemic mycosis in ailments with normal immune diseases.

How to secure

Schemes of drug administration

More precisely, the end of the lykarskiy will be able to lie down from the ailments, as well as the severity of it. It is necessary to continue the therapy with the cyme drug until quietly, as long as all clinical indications are not made to return to normal. It’s not a good idea to stop thinking right away if it’s a sign of illness. One vinyatka - tse pіkhvi candidiasis. Zazvychay enough one-time zasosuvannya, to overcome all the negativities, manifest the grief. In general, you can apply the following schemes:

In case of candidiasis or candidiasis - 4 capsules of 200 mg per day, in other and later - 2 capsules 1 time per day;
For cryptococcal infections - 2 capsules of 100 mg 2 times a day, in other and more - 1 capsule of 100 mg 2 times a day;
at streptococcal infections- one-time intake of 4 capsules of 150 mg;
In case of oropharyngeal candidiasis - 100 mg or 1 capsule, 1 time per day, stretching 1-2 times;
For the prevention of candidiasis in SNID-positive people - 1 capsule of 150 mg 1 time per day of life;
For atrophic candidiasis - 1 capsule of 50 mg 1 time per day for 2 months;
In case of candidiasis of mucous membranes - 200 mg, or 2 capsules of 100 mg, a day stretching 2-4 times;
In case of esophagitis - 1 capsule of 50 mg 2 times a day for 4 hours;
In case of bronchopulmonary infections - 1 capsule of 50 mg 2 times a day for 2 hours;
For vaginal candidiasis - a single dose of a capsule Mikosist 150 mg;
With candidiasis balanitis - a one-time intake of 150 mg of liquor;
In case of recurrent thrush - 1 capsule of 150 mg 1 time per week stretching out;
In case of immune suppression - 2 capsules of 100 mg 2 times a day, stretching a month;
For the prevention of immune suppression - 1 capsule of 150 mg 1 time per day with a stretch;
In case of endemic mycoses - 1 capsule of 100 mg 2 times a day for a long time;
In case of histoplasmosis - 2 capsules of 150 mg 2 times a day for 2 rock_v;
With paracoccidioidomycosis - 1 capsule of 150 mg per day for 1-2 rockyv;
With mycosis of shkirnykh pokriviv - 150 mg once a day or 50 mg once a day for 2-4 hours;
With dermatophytosis - 2 capsules 150 mg per day for 6 months;
In case of deprivation - 1 capsule of Mikosist 50 mg per day for 2 hours;
With generalized deprivation - 1 capsule of 100 mg with a stretch of 4 teaspoons;
In case of onychomycosis - 1 capsule of 150 mg per day for 3-6 months, everything should lie in the form of liquid growth of nigth plates (as the fungus is thumb, Loans are often borrowed for 6-12 months).

Vzhivati Mikosist can be children who have reached 5-6 years. Maximum dose for them, it is guilty that is lower than the boundary permissible for the grown-ups. Prodovzhuvati lіkuvannya with such a drug is necessary until quiet feast, as long as the signs of klinіchny oduzhannya do not appear. As soon as you stop giving the children of the word immediately, if you know it is a sign of illness, you will find yourself stuck with a further relapse.

The exact dose of the drug must be taken strictly for the duration of the day. In the middle, the child is guilty of trimming close to 3-10 mg of fluconazole per 1 kg of her weight per day. If wine is important for 10 kg, then wine can be taken from 30 to 120 mg per day. With a slight interruption, it is necessary to take the minimum dose, with important fungal infections - take the maximum.

Mycosyst for new-born children can be victorious only at the viglyadi rose for the first. The stench can’t be prokovnuty to finish off a large capsule by size. The dose of liquor is rozrahovuvatisya for this scheme, for children older. However, if the child did not reach the mark in 1 month, it is necessary to inject Mikosist 1 time every 3 days. So let it be unique negative infusion on internal organizations.

Prototype

Disrespectful to Mikosist's safety, it is categorically hardened to accept in offensive drops:

In case of allergy or sensitivity to the components of the drug;
With one-hour therapy with drugs, in the warehouses of any presence cisaprides, terfenadine, astemizole;
When implanted, hinidin or pimozide;
With the presence of illnesses, nirok abo pechіnki;
With heart-vindicated diseases;
With a low concentration of magnesium, calcium or calcium in the blood;
With damaged heart muscles;
Children who did not reach 5-6 years;
When falling ill with nirok and nirkova deficiencies.

Vicious Effects

Mycosyst - to finish off the baked liquor, like in the edge of a little bit of a wickedness. In the provinces of small populations, therapies by some other means can be the reason for such side effects:

Damage in the robotic slunk-intestinal tract;
Headache, zapamorochennya, court attacks;
Thrombocytopenia, agranulocytosis, leukopenia;
Increased cholesterol levels and triglycerides in the blood;
Reducing the concentration of glucose, hypocalm;
Damaged functionality of nirok;
Potential manifestations of allergic reactions, bronchial asthma.

special requests

Lіkuvannya Mikosіst is necessary to continue until quiet feasts, until the laboratory until the end of the day does not confirm the onset of a serious remission. If you finish, take the Lykarskiy back early, if you see it, you will be connected with the work of the remission. In this kind of vipad, vilykuvati will be more important. Through those who are willing to talk to the drug through nirks, people with a lack of a robotic organ will need to be protected.

In small cases, there is a toxic injection of Mikosist on the stove, which can cause lethal drops. You can also be spared to have patients with serious obstinate sickness: cirrhosis, fatty hepatitis and bagatitis. It is so much more possible for nastannyh reactions. It is not recommended to carry out treatment with Mikosist in people with puffins or SNID. They have a significant development of the development of serious side effects.

Yaksho at the grown-up people lykarsky drug fungal infection develops, with Mikosist it is innocuous to grow. Such a camp can easily become the cause of erithemi or bully fights. To protect the guilt of guilty people from the ruined in the exchange of words. Before the hour of therapy, it is even more important to continuously control the level of sugar, insulin and cholesterol in the blood. Through those who can wicklikati zapamorochennya, with a special protection to take the Mikosist, it is necessary for an hour to run, or robots with technology.

Zapobizhnі come in

Mycosyst is a breeze, like, in some cases, it’s okay to create an organism for a serious shkodi. On the alert, the guilty people are guilty, as they may have increased sensitivity to milk tsukru. In the warehouse of capsules there is a quantity of anhydrous lactose, which can provoke the development of serious side effects. It is also not easy to accept leaks with the presence of components, if you have an allergic reaction. Do not worry about self-care, please advise that you can provide the most optimal solution for you, and I will add a safe scheme for an ailment.

Interaction with other drugs

Mikosist is a lykarskiy zasib, which is to fix the straining infusion on the body. Do not expect Danium drug you can follow the links. Through the use of new medications, you can get a winnowing reaction:

Vikoristannya pid hour of vaginosti and thoracic treatment

Virobnik, without viprobubannya, yak Mikosist is injected into the period of the fetus and the baby itself during the period of breastfeeding. Skin vipadok individual, consultation with a doctor is required. The drug therapy is indicated for women who suffer from serous fungal infections. Insure that you are guilty of taking advice only from a consultation with a doctor, so that you can unify the development of serious acceleration.

Dіyucha speech fluconazole is consumed in the organism of the child through breast milk, which can be used for the development of the nerves.

analogs

Mykosist's offense to the lykarsky forms is a great number of analogies behind the common speech. Yaksho Mikosista will not be on sale, if you can, you can replace it with these capsules, in the warehouses such as fluconazole: Flucose. Fluconorm, Flucoside, Flucoral Fluconazole. You can also add a roschini Futsis, Procanazole or NOVIGAN. Yakshcho zh lykar prescribing you Mycosist viklyuchno, the most beautiful drug for the meanings. Unimportant to the similarity of the store, all preparations may be different features and contraindications.

Flucoral
fluconazole
Futsis Procanazole NOVIGAN

partnership

The part of Mikosist to finish nevisok - the whole likarskiy can be practically known without any reason in any pharmacy. The price of the drug can vary in the range of 10-20% through new trade nationalities. Call the tags for the upcoming prices.

Mikosist - antifungal lykarskiy zasib wide range dii, scho to enter the class of older triazole.

The fix component of Mikosist - fluconazole - is synthesized with a spoluca, which should be laid down to a group of triazole rivers. It has strong and selective powers: driving the fermentation of enzymes necessary for the life of the pathogen.

At the same time, pour only on the oleaginous, do not consume the ferment of the human body. Fluconazole induces life in the genus Candida of the common species, cryptococci, flower fungi. When it comes to acceptance, it’s quick and easy to get used to in general: accessibility to yoga is 90%.

Clinical-pharmacological group

Antifungal drug.

Mind that term zberigannya

Available without a prescription for a liquor.

prices

Skіlki kostu Mycosist? The average price in pharmacies is about 700 rubles.

Form vipusk and warehouse

Mycosyst is dispensed in the form of hard gelatin capsules of 50, 100 and 150 mg and in the form of a bottle for infusion. The most frequent in medical practice is Mikosist 150 capsules.

The main reason for this is fluconazole.

Mikosist 50 is 50 mg to fluconazole, Mikosist 100 - 100 mg, and Mikosist 150 - 150 mg to fluconazole.

In a 1 ml solution for infusion, 2 mg of fluconazole should be taken.

Additional services in the warehouse of Mikosist є:

capsules - coloidal silicon dioxide, magnesium stearate, povidone, talc, corn starch, lactose;
rozchin - distilled water and sodium chloride.

pharmacological effect

Fluconazole is a representative of the class of older triazole and is used to selective reactions in the synthesis of sterols, which is found in fungi cells. Vono zdatne blockuvati the process of converting lanosterol mushrooms on іvnі clitin into ergosterol. At the same time, an increase in the penetration of the cell membrane is indicated. For new, androgenic activity is not characteristic.

The Danish drug is highly effective in treating illnesses, including Candida spp., Microsporum spp., Cryptococcus neoformans, Trichophyton spp., Coccidioides immitis Blastomyces dermatitidis and so on.

When the capsules are taken, the body of any given fluconazole is allowed to get wet, with a bioavailability of close to 80-90%. Acceptance of їzhі does not pour on yogo absorption. As a rule, the drug is used to fix it with a higher dosage for increasing the concentration of speech and povnotsinnyy. The main component appears practically in all fabrics, physiological reasons, so as without any difficulties, it is necessary for all barriers to organism. The organism of Mikosist is vivodied for help nirok.

Shown to sucking

Where do you help? Mycosyst is indicated for such illnesses:

Mykozy groin area, tuluba, shkiri.
Genital candidiasis: vaginal (chronic or recurrent hospitals).
Mucous membranes candidiasis: mouthwash(Including atrophic candidiasis of the mouth emptying, wickedness to the nose of dentures), stravohode, pharynx; candiduria; non-invasive broncholegenic infections; prevention of re-development of oropharyngeal candidiasis in patients with SNIDom.
Gliboki endemic mycoses (including paracoccidioidomycosis, coccidioidomycosis and histoplasmosis in patients with normal immunity).
Prevention of fungal infections in patients with malignant new patients who are sick before such infections in the case of exchange therapy or chemotherapy with cytostatics.
Cryptococcosis: prevention of relapses of cryptococcosis in patients with SNIDOM, with organ transplants and in those who have immunodeficiency disorders, cryptococcal sepsis, cryptococcal meningitis, cryptococcal pulmonary infections.
Generalization of candidiasis, dissemination of candidiasis, candidiasis and other forms of invasive candidiasis infections (eyes, endocardium, blackheads, recurrent and mental therapy), including those of extreme before the diagnosis of candidiasis - treatment and prophylaxis.

Prototype

absolute:

Admission with astemizole;
Lactase deficiency, lactose intolerance, glucose-galactose malabsorption (for capsules);
Period of breastfeeding (in breast milk, the drug is taken in the same concentration as in plasma);
Immediately vicorianny with terfenadine (in case of continuous intake of fluconazole at a dose of 400 mg per supplement and food) and cisapride, in addition to increasing the QT interval with drugs and improving the development of severe heart rhythm disorders;
Hypersensitivity to components as well as those close to the structure of azole spolucs.

Vidnosnі (zastosovuvati with supervised protection, fragments of possible development accelerated):

Nirkova і / abo pechinkova lack;
Intolerance to acetylsalicylic acid;
One hour vikoristannya with rifabutin (you can get uveit);
Potentially proarrhythmogenic will become in patients with the presence of multiple factors in the risk of disease (organic heart disease; additional drugs that cause arrhythmias, disruption of the electrolyte balance);
The appearance of viscera on aphids of fluconazole in patients with invasive / systemic fungal infections, as well as superficial fungal infections;
Addition of other drugs, which are metabolized by additional enzymes in the cytochrome P450 systems.

With the vaginosti stasis of Mikosyst, it is possible only for the development of secondary reactions.

Vikoristannya with vaginosis and lactation

Oskilki dyucha speech Mikosist - fluconazole penetrates through the placenta to the fetus and into breast milk, which are found in them in the same concentration, as in the woman's blood, then it can be used for vaginosity that year, when there are brown breast, in the same concentration. for the child.

In Danish hour, with a glance at the single dose of viciousness and to reach a large number of precautions, they showed in practice the lack of longevity of the drug for the fetus, and they use Mikosist for the treatment of vaginal thrush for the treatment of vaginal thrush. In some cases, if the transfer of Mikosist is more trivial, there are contraindications to vaginal and year-old women.

Dose-up and supply-up methods

In the instructions for use, it is intended that the Mycosist capsules are taken in the middle. Doroslim it is recommended to set the offensive dosage regimen:

In case of cryptococcal infections, the dose of fluconazole should be 400 mg 1 time / day on the first day of treatment, nadal - 200-400 mg 1 time / day. The triviality of treatment in case of cryptococcal infections is to be found in the form of clinical efficiency, in the case of clinical preoccupations, and in the habit of becoming from 6 to 8 types.
It is recommended that the triviality of treatment during the therapy of cryptococcal meningitis is to become 10-12 months after a negative result of microbiological examination of the spinal cord.
For the prevention of relapse of cryptococcal meningitis in patients with SNID after the completion of the first course of primary therapy, fluconazole should be prescribed at a dose of not less than 200 mg / add for a trivial period.
In case of candidiasis, disseminated candidiasis and other invasive candidiasis infections, the dose of fluconazole should be 400 mg in the first dose and 200 mg on the coming days. If necessary, the dose of the drug can be increased to 400 mg / day. The triviality of the policy is to be found in the classroom efficiency.
With an important systemic candidiasis, you can increase the dose up to 800 mg / day. The triviality of therapy is based on clinical efficiency. Slide prodovzhuvati not less than 2 probabilities to discard negative blood culture or to disclose symptoms of illness.
In case of atrophic candidiasis, empty mouth, tied with dentures, fluconazole should be administered 50 mg 1 time / add for 14 days at the same time with antiseptic methods for cleaning the prosthesis.
In case of oropharyngeal candidiasis, including ailments with impaired immunity, the dose of fluconazole should be 50-100 mg 1 time / add for 7-14 days. For the prevention of recurrences of oropharyngeal candidiasis in patients with SNID after completing the main course of primary therapy - 150 mg 1 time per day. If there is a need for treatment, it can be continued, especially in case of severe damage to immunity.
In case of other candidiasis infections, for example, with esophagitis, non-invasive bronchogenic infections, candidiasis, candidiasis of the skin and mucous membranes, the dose should be 50-100 mg for 14-30 days.
With important candidiasis of mucous membranes - 100-200 mg / day.
For vaginal candidiasis - 150 mg once a day. To reduce the frequency of recurrences, vikoristovuyut 1 time per month, 150 mg for 4-12 months, sometimes it can be more frequent.
For the prevention of fungal infections in ailments due to malignant neoplasms, the dose of fluconazole should be 50 mg 1 time / day until a quiet period, while the ailments are in the group of those who are susceptible to cytostatic therapy.
In case of severe endemic mycoses, the drug can be consumed in a dose of 200-400 mg / add for 2 years. The triviality of therapy is individualized; you can become 11-24 months with coccidioidomycosis; 2-17 months for paracoccidioidomycosis and 3-17 months for histoplasmosis.
For the prevention of candidiasis, the recommended dose of fluconazole is to become 50-400 mg 1 time / dose, lying down the stage of the development of fungal infection. With the presence of a high risk of generalized infection, for example, in ailments with a cleansed, swollen, abnormally effective neutropenia, it is recommended to make the dose 400 mg 1 time / day. Fluconazole should be used for a few days before neutropenia appears; If the number of neutrophils is adjusted up to 1000 / μL, then continue for 7 dB.

For children, the triviality of therapy is based on a clinical and a microchological effect. Dobova dose for the whole category of ailments is not guilty of changing taku among grown-ups.

Vicious Effects

During the period of Mikosist therapy, there may be some side effects from the side of these systems to the body:

Nervous system: sudomi, zapamorochennya, head b_l;
Organ blood formation: agranulocytosis, neutropenia, thrombocytopenia, leukopenia;
Rechovin exchange: hypocalypse, hypertriglyceridemia, hypercholesterolemia;
Heart-sudinna system: tripping / measuring of shlunochkiv, increasing on the electrocardiogram of triviality to the QT interval;
Herbal system: impaired liver function (hepatocellular necrosis, including with a lethal result, hepatitis, zhovtyanitsya, altered activity of puddled phosphatase, transaminases, hyperbilirubinemia), malaise, abdominal pain, abdominal pain, abdominal pain
Allergic reactions: bronchial asthma (most often in case of ASA intolerance), anaphylactic reactions (including abnormalities of shkiri, angioedema, crotchis, exaggeration of the viscera), Stalin's syndrome syndrome, multidrug syndrome
Іnshi: alopecia, impaired function of nirok.

Overdose

In general, the washing of the slunk, intestines, intake of intestinal sorbents is carried out ( assets not vugilla), symptomatic therapy And also hemodialis (apparatus for cleaning blood).

special requests

Slide prodovzhuvannya drug "Mikosist", until a clinical and hematological remission appears.

Before the end of the therapy, I am overwhelmed with relapses. As it is already said, patients with a nirkovy lack of guilt vikoristovuvati the medication as carefully as possible, some of them are vitally important with nirkas. Dozuvannya at pre-construction lіkuvannі slіd conduct, vrahoyuchi KK. Inodi storage of fluconazole is a very toxic infusion into the liver, so it is necessary to control the function of the given organ. When vyavlennі sign urazhennya slіd pripiniti with the drug.

Patients on the “Mycosist” hospital had one or more symptoms of exfoliative school reactions, for example, toxic epidermal necrolysis and Stevens-Johnson syndrome. Ailments on new malignancies and SNIDs are more severe until severe mental reactions are diagnosed with vicious drugs with the addition of fluconazole. If in the course of therapy for superficial fungal infections, a visip will appear, it is necessary to skasuvati.

When people are diagnosed with an invasive or systemic fungal infection, the drug should be able to be avoided and the drug should be taken into account in order to develop a multiform erythematosus or bulbar disease. After an hour the drug "Mikosist" can be used to get rid of the problem, so the patients need to take special care when robots with technology and keruvans by motor transport.

likarska vzaєmodiya

When the drug is vicious, it is necessary to vrahovuvati in conjunction with the following leaks:

Fluconazole in case of one-hour intake can increase T1 / 2 of old sulfonylsectivities, that is, in case of alcohol consumption, it is possible to develop hypoglycemia.
Patients who receive fluconazole and indirect anticoagulant coumarin, need to monitor the prothrombin hour, some may be reduced.
With a one-hour intake of rifampicin and fluconazole, the Cmax and T1 / 2 decrease, which, if necessary, a one-hour consumption of fluconazole.
Immediate consumption of fluconazole and phenytoin can be increased by increasing the concentration of phenytoin in a clinically significant step, which reduces the dosage.
Drinking fluconazole and rifabutin is superfluous to increase the concentration of fluconazole and the potential for development of uveitis.
I'll look back at the winners of the serious, clutter up the life arrhythmias in ailments, who take anti-fungal infections - lost azole in combination with terfenadine, is a spilny method of contraindications.
In case of alcohol intake of fluconazole and cyclosporine, it is recommended to control the concentration of residual blood in the blood, some of which may be reduced.
With a one-hour intake of fluconazole, an increase in the concentration of zidovudine in blood plasma is possible. Patients who receive such a combination, later helped to promote the development of side effects to zidovudine.
In case of one-hour reception of fluconazole and cisapride, there are descriptions of vague reactions from the side of the heart, including paroxysms of lingual tachycardia. One-hour reception of contraindications.
Immediately consuming fluconazole and midazolam to produce a significant increase in the concentration of the remaining in the blood plasma and the development of psychomotor reactions.
By taking fluconazole, to reduce the average rate of blood plasma theophylline to a decrease in the average rate of blood plasma, from the same, to increase the development of toxic effects of theophilin and its overdose.
With a one-hour intake of fluconazole and hydrochlorothiazide, the concentration of fluconazole in blood plasma increases by 40%.
It is necessary to take precautions when consuming fluconazole in patients who are consuming these drugs at once, so that they are metabolized by isoenzymes of the cytochrome P450 system.
With a one-hour intake of fluconazole and tacrolimus, the concentration of the rest in the blood is increased, which leads to an increase in the risk of nephrotoxicity.

In this statistic it is possible to learn about the instructions for the preparation of the drug Mycosist... The presentations of the guide to the site are presented with the help of this tag, as well as the thoughts of the friends of the fakhivts from the victorious Mikosist in their practice. There is a great way to actively add your messages about the drug: it helped or did not help the liking to get sick, as it was spared the acceleration and side effects, it may not have been declared by the virobnik in the abstract. Mikosist's analogs with obvious structural analogs. Vikoristannya for the treatment of candidiasis (thrush) and other mycoses in older adults, children, as well as for vaginosis and breastfeeding. Warehouse for the drug.

Mycosist - antifungal drug... Fluconazole (for the drug Mikosist), a representative of the class of triazole antifungal species, is a selective inhibitor of sterol synthesis in fungal cells.

Fluconazole, being Visokovibirkovo for P450 fungi, practically does not drive the cytochrome P450 system into the human body (in some cases with іraconazole, clotrimazole, econazole and ketoconazole in the small area of cytochrome).

Not volodya androgenic activity.

Active schodo zbudnik_v mykoz_v, viklikanich Candida spp. (Candidi), Cryptococcus neoformans (cryptococci), Microsporum spp., Trichophyton spp. The activity of fluconazole has also been shown in models of endemic mycoses, including infections, blastomyces dermatitidis, Coccidioides immitis and Histoplasma capsulatum.

warehouse

Fluconazole + additional speech.

Pharmacokinetics

Internally introduced Mycosyst penetrates well into tissues and organisms. Concentration of the drug in slins, sputum, breast milk, loam and peritoneal and analogous concentration in blood plasma. In ailments with fungal meningitis, fluconazole changes in the spinal cord at 80% of the total concentration in plasma. Concentration in plasma is in direct proportion to deposition of doses. 90% of the concentration is equally important to reach up to 4-5 days with the addition of 1 time per day. Zastosuvannya on the first day of the dose, doubled the dose, allowing you to reach 90% equally important concentration until another day. Uyavny volume rose to close up to the volume of water in the body. Plasma proteins contain 11-12% fluconazole. Metabolites in peripheral blood are not detected. Fluconazole vivoditsya from the body, in the main, nirkami; at the same time, approximately 80% of the administered dose is delivered in an uninterrupted view.

showing

cryptococcosis: cryptococcal meningitis, cryptococcal infections of legends and shkiri; cryptococcal sepsis; prevention of recurrence of cryptococcosis in patients with SNID, during organ transplantation or in cases of immunodeficiency;
generalization of candidiasis; candidiasis, dissemination of candidiasis and іnshі forms of invasive candidiasis infections (infections of the worm, endocardium, eyes, mental and secular nobles), incl. in ailments who receive a course of cytostatic or immunosuppressive therapy, as well as in the presence of other factors, to develop candidiasis - treatment and prophylaxis;
candidiasis of mucous membranes: empty company, incl. atrophic candidiasis of empty mouth, dressings for dentures; pharynx; stravohode and non-invasive broncholegenic infections, candidiasis; prevention of recurrence of oropharyngeal candidiasis in patients with SNID;
genital candidiasis: vaginal (gostry abo chronic recurrent);
prevention of fungal infections in ailments from malignant new diseases, such as sick before such infections in chemotherapy with cytostatics or exchange therapy;
mykozy shkiri, tila, groin area;
gliboki endemic mycosis, including coccidioidomycosis, paracoccidioidomycosis and histoplasmosis in patients with normal immunity.

formy vipusku

Capsules 50 mg, 100 mg and 150 mg

Roschin for infusions 2 mg / ml (in ampoules).

Іnshikh lykarskikh forms of the drug, be it candles, ointment or cream, not іsnu.

Instructions for suction and dosage regimen

In case of cryptococcal infections, the dosage of Mikosist should be 400 mg 1 time per dose on the first day of treatment, nadal - 200-400 mg 1 time per dose. The triviality of treatment in case of cryptococcal infections is to be found in the form of clinical efficiency, on the basis of certain microbiological preferences, and in the habit of becoming from 6 to 8 types.

For the prevention of the recurrence of cryptococcal meningitis in patients with SNID after the completion of the main course of primary therapy, Mikosist should be prescribed in a dose of not less than 200 mg for a prolonged period of time.

In case of candidiasis, disseminated candidiasis and other invasive candidiasis infections, the dose of fluconazole should be 400 mg in the first dose and 200 mg on the coming days. If necessary, the dose of the drug can be increased to 400 mg per dose. The triviality of the policy is to be found in the classroom efficiency.

With an important systemic candidiasis, you can increase the dosage up to 800 mg per dose. The triviality of therapy is based on clinical efficiency. Slide prodovzhuvati not less than 2 probabilities to discard negative blood culture or to disclose symptoms of illness.

In case of oropharyngeal candidiasis, including ailments with impaired immunity, the dose of fluconazole should be 50-100 mg once a day for 7-14 days. For the prevention of recurrences of oropharyngeal candidiasis in patients with SNID after completing the primary course of primary therapy - 150 mg 1 time per day. If there is a need for treatment, it can be continued, especially in case of severe damage to immunity.

In case of atrophic candidiasis, an empty mouth, tied with the nose of dentures, fluconazole should be administered 50 mg once a day for 14 days at the same time with antiseptic methods for cleaning the prosthesis.

In case of other candidiasis infections, for example, with esophagitis, non-invasive bronchogenic infections, candidiasis, candidiasis of the skin and mucous membranes, the dose should be 50-100 mg for 14-30 days.

With important candidiasis of mucous membranes - 100-200 mg per add.

For the prevention of fungal infections in ailments due to malignant new products, the dose of Mycosist should be 50 mg 1 time for a quiet meal, as long as the ailments are in the group of people who are susceptible to cytostatic and commercial therapy.

For vaginal candidiasis - 150 mg once a day. To reduce the frequency of recurrences, vikoristovuyut 1 time per month, 150 mg for 4-12 months, sometimes it can be more frequent.

For the prevention of candidiasis, it is recommended that the dose of fluconazole be 50-400 mg 1 time in advance in the fallow state of the stage of development of fungal infection. With the presence of a high risk of generalized infection, for example, in ailments with a cleansed, swollen, or even gross neutropenia, it is recommended that the dose be 400 mg 1 time per dose. Fluconazole should be used for a few days before neutropenia appears; If the number of neutrophils is adjusted up to 1000 / μL, then continue for 7 dB.

In case of severe endemic mycoses, it is possible to consume the drug in a dose of 200-400 mg for 2 years. The triviality of therapy is individualized; you can become 11-24 months with coccidioidomycosis; 2-17 months for paracoccidioidomycosis and 3-17 months for histoplasmosis.

In children, the drug is not consumed in a good dose, but it is changed in older adults. It is a triviality to lie down as a classic and ecologic effect.

For the elimination of generalized candidiasis and cryptococcal infections, the recommended dose is 6-12 mg / kg per day, depending on the severity of the disease.

For the prevention of fungal infections in children with decreased immunity, in some patients the development of infections with neutropenia, as well as in the development of cytotoxic therapy for chemotherapy, and for the development of

Newborns have Mikosist more often, since in their first 2 years of life the drug is prescribed at the same dose (in mg / kg), and in older children, even with an interval of 72 years. For children at 3-4 age, the same dose should be administered at intervals of 48 years.

In patients of a kidnapped person, when they are out, the functions of the patient are broken down, followed by specific recommendations for the dosage of the drug.

Rules for sucking the drug

Introduce vnutrіshnyovenno drip from shvidkіstyu not more than 20 mg (10 ml) in xv. When transferring from intravenous injection to the intake of capsules and navpaki, it is not necessary to change the dose of the drug.

Mycosyst solutions for infusion sums with advances: 20% glucose, Ringer's, Hartman's, calcium chloride in glucose, sodium hydrocarbonate, 0.9% sodium chloride. Infusion to fluconazole can be carried out with the help of additional sets for transfusion, one of the pereinfusions for transfusion.

Pobichna diya

nudity of blues;
diarrhea;
flatulence;
beating in the stomach;
zm_na relish;
impairment of liver function (hyperbilirubinemia, increased activity of liver transaminases, alkaline phosphatase, zhovtyanytsya, hepatitis, hepatocellular necrosis, including with a lethal result);
head beel;
zamorochennya;
sudomi;
leukopenia, thrombocytopenia, neutropenia, agranulocytosis;
shkirny visip;
bagatoformna erythema (including Stevens-Johnson syndrome);
toxic epidermal necrolysis (Lyell's syndrome);
anaphylactic reactions (including angioeurotic nabryak, accusation, kropiv'yanka, sverbіzh shkіri);
bronchial asthma (often with intolerance to acetylsalicylic acid);
increase in the triviality of the QT interval on the EKG;
fewer / threefold shlunochkiv;
hypercholesterolemia;
hypocalypse;
deterioration of the function of nirok;
alopecia.

Prototype

one-hour intake of terfenadine (for a long-term intake of the drug at a dose of 400 mg for a dose of food);
immediately zasosuvannya astemizol;
period of lactation (breastfeeding);
childish vіk up to 6 months (for reception in the middle);
Sensitivity to the components of the preparation is adjusted, or those close to the structure of azole spolucs.

Stagnation during vaginosis and breastfeeding

Zastosuvannya drug Mikosyst with vaginosti can only be in the fall, if there is a potential for coryza for the mother, perevischurizik for the fetus.

Fluconazole is found in breast milk in the same concentration as in plasma, and its significance in the period of lactation is contraindicated.

Stagnation in lithuanian children

In patients with a kidney disease, when they are out, there is a sign of a nirkovo lack of success in the presence of a drug dosage due to the regimen.

Zasosuvannya in children

special requests

Fluconazole treatment must be continued until clinical and hematological remission occurs. Before the end of the process, the disease should be brought to relapse.

Oskilki fluconazole vivodvodvodvodvod, nirkami, followed by the care of patients with nirk deficiency. In case of trivial lіkuvannі with fluconazole, the dose should be carried out with the urinary tract therapy.

In rare cases, Mikosyst's supravigation has a toxic effect on the liver, incl. і with a lethal result, the head rank among patients with serious supporters... It is necessary to control the function of the stove. When there is a sign of liver damage, which can be tied with a dose of fluconazole, the drug should be changed.

On the basis of a single drug, the patients had one single drop in the development of exfoliative school reactions, such as Stevens-Johnson syndrome and toxic epidermal necrolysis. Ailments of SNID and malignant newly approved drugs increased to the development of severe malignant reactions in case of stagnant drugs. When a patient has an hour to diagnose a superficial fungal infection, it is possible to apply fluconazole from the intake, the drug should be taken into account. When a visipu appears in patients with invasive / systemic fungal infections, fluconazole is retarded and spasuvati fluconazole with the appearance of bullosa diseases or multiforme erythemias.

It is necessary to control the prothrombin hour in patients who immediately take fluconazole and indirect anticoagulant coumarin series.

Inflow to the building of keruvati by transport means and mechanisms

Patients should be protected during keruvannas with transport means, for when they are robotic with technology, some hours before taking fluconazole can be spoiled.

likarska vzaєmodiya

Patients who receive Mycosyst and indirect anticoagulants of the coumarin series, the necessary control of the prothrombin hour, some of them can be improved.

Fluconazole in case of one-hour intake can increase T1 / 2 of old sulfonylsectivities, that is, in case of alcohol consumption, it is possible to develop hypoglycemia.

Immediately the consumption of Mikosyst and phenytoin can be superseded by the increase in the concentration of phenytoin in a clinically significant step, which is a decrease in the dose.

Drinking fluconazole and rifabutin is superfluous to increase the concentration of fluconazole and the potential for development of uveitis.

In case of alcohol intake of fluconazole and cyclosporine, it is recommended to control the concentration of residual blood in the blood, some of which may be reduced.

I will look at the diagnoses of those who are serious, threatening arrhythmias for life in ailments, who take anti-fungal infections - the common azole in addition to terfenadine, which is a spilial source of evidence.

With a one-hour reception of Mycosyst and cisaprida, there are descriptions of non-essential reactions from the side of the heart, including paroxysms of the shlunochkovo tachycardia. One-hour reception of contraindications.

With a one-hour intake of fluconazole, an increase in the concentration of zidovudine in blood plasma is possible. Patients who receive such a combination, later helped to promote the development of side effects to zidovudine.

By taking fluconazole, to reduce the average rate of blood plasma theophylline to a decrease in the average rate of blood plasma, from the same, to increase the development of toxic effects of theophilin and its overdose.

Immediately consuming fluconazole and midazolam to produce a significant increase in the concentration of the remaining in the blood plasma and the development of psychomotor reactions.

With a one-hour intake of fluconazole and hydrochlorothiazide, the concentration of fluconazole in blood plasma increases by 40%.

With a one-hour intake of fluconazole and tacrolimus, the concentration of the rest in the blood is increased, which leads to an increase in the risk of nephrotoxicity.

Analogs of Likarskiy drug Mikosist

Structural analogs for common speech:

Vero Fluconazole;
Disorel Sanovel;
Diflazon;
Diflucan;
Micon;
Medoflucon;
Mikomax;
Mikoflucan;
Nofung;
Procanazole;
Fangiflu;
Flucosan;
Flucoside;
Flucomabol;
Flukomitsid;
fluconazole;
Fluconorm;
Flucoral;
Flucorus;
Flucor;
Flucostat;
Forkan;
Fungolon;
Tsiskan.

When there are analogs of a drug for a daily speech, you can go to the lower level for an illness, such as a supplementary drug, and an analogy for a drug.

Mycosyst is a highly anti-fungal lykarskiy for a wide range of children. It stagnates in the presence of fungal infections, which are localized on the sheaths, mucous membranes, the surface of the skin and internal organs.

The essence of the drug is in the blocking of the building before the multiplication, for the second time, and for the repeated appearance. Krym, win with success to get stuck to prevent the diagnosis of infection in individuals with weakened immunity (for example, in those with a diagnosis of VIL and patients with a cystic brain transplant).

On the basis of popular analogs, it’s not a ruinous oven - the customization on it is minimal. Yak inheritance, a number of side effects from the reception given in vain nagato is lower in proportion to the competitive leaks of antifungal activity, and the price is to be added.

Form vipusku and warehouses

On the current pharmaceutical market, the drug is presented in two versions:

capsules;
Ridky difference for internal introduction.

Before the warehouse of Likarskiy, it is necessary to include fluconazole as the main active speech and a number of additional Ingredients. In capsules:

silica;
milk succor (lactose);
starch;
stearic acid;
talc;
povidon.

In the presence of sodium chloride and distillation of drinking water.

Capsules are dispensed in three doses - 50, 100 and 150 m fluconazole per 1 ml of rіdini.

pid lykarskiy practice larger formulation required for the preparation є capsules 150 m It is important to note that the brand often characterizes the tablet, but in this form the drug is not carried out. Also, do not let the wine go to the viglyad vaginal test, Scho is recognized with thrush. Cream can be found in virobnik boxes.

In the case of a capsule form of a vipusk, the preparation can be used as a powder of any kind of powder, in the middle of a special hard shell with a complex of gelatin and titanium dioxide. The skin of such a capsule is equipped with a light crust that does not penetrate, behind the color it is easy to identify the drug. Zokrema, capsule head 50 mg of light-blue vidtinok, 100 mg - birusovy color, and 150 mg - blue color. Size and size of capsules. Їх number in one package - 1, 2, 7, 28 pieces.

Rozchin for internal equipment is sold in bottles of 100 ml. So as a dose of fluconazole in 1 ml solution = 2 mg, in 100 ml of this amount will be 200 mg.

Pharmacokinetics

In case of oral administration from the system shlunkovo-intestinal tract a great part of the accepted dosi is consumed in the shelter. The maximum through the second year, when the maximum dose of the drug will be reached in the blood cells, will be reached. For an additional blood flow, Mycosyst is consumed in tissues, organisms and systems, especially strongly concentrated in balls of shkiri and sweaty vines. The drug can be taken without binding before implantation of the drug. On yogo sootuvanism does not pour in at first, for an hour or so.

It is possible for a person to penetrate into the mustache of a child, to be violated by human organism - pit, intimacy, Breast milk і t. P. Effective concentration, in them to be spared through a quarter of the time to receive the cost and to last for 24 years.

50% of the otrimano dose will be delivered to the body in 30 years. A great part of the robotics is laid on nirkas, and what makes the funkier the stink, the better the way to get the leaks. Vidsotki, how the speeches go feces for additional help.

Shown to sucking

thrush in women;
cholovichi show candidiasis;
candidiasis of organ poisoning;
groin epіdermofіtіya;
shkіrni types of mycosis in the difference in efficiency of muscular preparations;
prophylactic therapy of mycoses in cancer patients who undergo a course of chemotherapy or exchange therapy;
a mix of organ transplantation, antibiotics intake, in case of immunodeficiency diseases in the body;
fungal infections of mucous membranes;
cryptococcal menіngіt;
cryptococosis;
detection of fungal infection of nigty plates (strictly for the recommendation of the doctor)

Prototype

It is obvious from the instruction because of the registration of the Mikosist varto unicati for:

setting the patient's sensitivity to fluconazole;
receive a patient Cisapride and H1-antihistamines;
lactose intolerance;
vіtsі younger than six months;
in the period of chest vigodovuvannya.

Only after consultation with a doctor and assessments of young risiks, admittedly, if:

pathological damage to the function of the liver and nirok;
take rifabutin;
ailments of the heart-vascular system;
allergies to acetylsalicylic acid;
viniknennі visipu of unclear genesis.

Okremo varto zgadati about taking the drug by vaginal women. Fix the last one only after an in-person consultation with a Fakhivite laboratory dosages, And also with the permission of the gynecologist, which spares the vagina. The drug is indicated to mothers only in case of important forms of fungal infections, which require non-specific therapy.

Peculiarities of overdose

An overdose of tsikh likiv can only be consumed for a dose of a dose of 800 mg. Until її characteristic symptoms next to bring:

tediousness and bloating;
diarrhea;
bile in the abdomen;
vidchuttya zduttya;
twisting of relish views;
zamorochennya;
mіgren;
shkirni visipannya;
swelling;
quay Kvinke;
asthmatic attack;
the destruction of the nirk function;
arrhythmia;
increase in blood cholesterol levels;
oblisinnya;
sudomi;
hypersensitivity;
in important cases - hallucinations and paranoid stances.

Persha can help you in this vipadka - come in from the slunk hole. Because of the patients, it is necessary to give a certain amount of time before the procedure for hemodialysis. Symptoms, tight-fitting stance of a sick person is permissible to be treated with drugs if necessary.

The patient before the cob is guilty of taking the drug, but the need to control the liver's robots is guilty. The first signs of the first toxic lesion given to the organ slid terminovo zupiniti with antifungal zasobu.

Clinical preliminaries showed the drug that, in some cases, I can provoke a damaging and anteriorly prone condition. To that, for the period of the development of the robot, the robot is aware of the increased concentration of respect and responsiveness. These recommendations are worthy of water quality. If you don't seem to be moody, we should be as careful and respectful as possible to the power of safety. I call these recommendations from the deyakie fahivtsi as spirits, so only some of the patients have gone bitter appearances... Matter of all, a large number of people did not pour the drug into the psychomotional camp.

Instructions for storing

The necessary form and dosage of the drug is indicative of only a competent medical practitioner, depending on the severity of the illness and assessment of the patient's health. For vipadok, I have a consultation with a drug that is not available, in a leather package detailed diagram welcome.

For older adults:

With the therapy of fungal infection with Candida: 400 mg per day on the cob taken from the changes in the dose for the next dose. at gostrom perebіgu zhvoryuvannya dobovu dose is allowed to increase the maximum amount.
In case of cryptococcal infection: similarly with a stretch of six types.
In case of infection of fungal nature in an empty company: 100 mg each day for 1-2 days. Throats: 100 mg, stretching 2-4 times.
For the treatment of small fungal infections: 50 mg per dob for 7-14 days.
For the treatment of mycosis of the feet: 300 mg daily for a period of 1.5 months in a fallow area. In the middle of the course, you can get an additional one-time dose of 300 mg.
In case of mycosis of nigtiv: 150 mg once every 7 days until the moment the nigth plate is lifted.
For the prevention of fungus: up to 400 mg of the drug per day for an hour of infection.
For the prevention of cryptococcal infections: 200 mg of daily, used for the sick person and the results of analyzes.

Children are 6 months old to the rock Mikosist is given for the sign of the doctor. Vibir fakhіvtsіv often shy away at the cinnamon stick, so as tablets and capsules for children it is easy to covtati. Dozuvannya rozrahovuєtsya in an individual order. The indicator of mass is taken as a basis. Vyhodyachi zі spіvіdnoshennya 2-12 mg of diyuchoіy speech per skin kilogram, carried out rozrakhunok. For example, a patient is important 15 kg. Yogo dobova dose can become 30 to 180 mg per dose. Within the framework of the whole interval, the license will select the scheme of treatment. In vinyatkovyh vipadkah, it is allowed to introduce a distribution to children younger than pivrok. However, be careful with an interval of not less than three dib until reaching 1 month and two dib for 2-5 months.

Until the people of the kidnapped category, who are not designated as a likare, and the sickness of the day, are stuck with the norms.

We are sick with pathologies nirok the drug Vipisu lykar.

Capsules to the drug are taken in a whole, kovtayuchi, not rozzhovyuchi, washed down with a small amount of pure non-gaseous water. Piti їkh can be done at any hour, do not lie down from the receptions. However, it is recommended to start working at approximately one and the same hour, but in the first half of the day.

In the course of infection, it is necessary to take a number of hygienic visits to prevent re-infection (for example, disinfestation of manicures, tools, lower blizzards, pancakes, blasts)

As soon as it became unplanned replacement of the proponated dose to the drug, it was not possible to visit the drug. You can, if you need to wash the slunker, come in.

If the prescribed dose is missed, it is not necessary to substitute the subordinate doses for the drug. It is easy to reach the end of the process with an individual scheme.

Mikosist, instructions for storing what to get into the skin packaging, you need to take a course. Independently, without a reason, interruption of therapy, in case of a loss of all symptoms of infection, is more burdensome for a risk of a relapse of illness.

In case of any kind of food, one hundred percent of the welcome, one dozen, self-esteem in the course of the journey, it is necessary to turn to one’s likar.

About competitors

On the current day, analogs of Mikosist and its synonyms are everywhere on the Russian pharmaceutical market. Who has a difference between two different witnesses? Synonymy - tse anti-fungal likarski zasobi Fluconazole can be stored in your warehouse. Analogs are drugs that may be active in the warehouse, but similar in strength to the antifungal blow. Yak butt to the first can be introduced by Diflucan, Flucosan, Flucostat, Tsiskan and іn. Analogs - Irunin, Teknazol, Orungamin, etc. Dany analogs are dispensed into capsules, roschini, cream, ointments and tablets.