Acetylcholine is a structural formula. Acetylcholine is a neurotransmitter mediator

Neuromediators play an important role in the proper functioning of the nervous system of people. One of these words, acetylcholine, is an organic molecule, the manifestation of which is characteristic of the brain of young fellows, birds and, of course, people. For example, the role of the neurotransmitter acetylcholine in human organisms is why it is so important to know the way to promote acetylcholine in organisms.

What is the neurotransmitter acetylcholine and its function?

The chemical formula of the neurotransmitter acetylcholine is CH3COO (CH2) 2N + (CH3). Qia organic molecule plays a role in the functioning of the central and peripheral nervous systems. Mice synthesis of acetylcholine - axoni nerve cells, Records, necessary for the formulation of acetylcholine: acetyl coenzyme A and choline (vitamin B4). For the balance of this mediator, acetylcholinesterase (enzyme) is formed, such as superfluous acetylcholine for choline and acetate.

functions of acetylcholine

improvement of cognitive health;
polypshennya nerve-muscle connection.

It seemed that the neurotransmitter acetylcholine didn’t only help to improve memory and reception, but also to help the brain to develop old and new help - those who are going to remember it, now, but it’s all right.

At the membrane of myazovykh cells there is H-cholynorecpetori, which are sensitive to acetylcholine. If acetylcholine is found to be a receptor of this kind, they consume sodium in the cells of the ointments, as a result of which the ointments speed up. As for the action of acetylcholine on the heart ointment, the frequency of the heart will change very quickly.

Deficiency of the neurotransmitter acetylcholine: causes and methods of improvement

With a change in the level of the neurotransmitter acetylcholine, acetylcholine deficiency is prevented.

symptoms deficiency acetylcholine:

inability to hear;
lack of dignity is concentrated;
lack of memory of memory and information (loss of memory);
general processing of information;
fatty liver metamorphosis;

If the level of acetylcholine in the body is normalized, and the price for help correct eating, Zapalennya to drive, and the ringing between meats and nerves fills up.

To the risk of lowering the level of the neurotransmitter acetylcholine to:

marathon runners and athletes who are right to show off;
people who are evil with alcohol;
vegetarians;
people, ratsion harchuvannya that are not balances.

The main bureaucrat, who has a lowered or increased acetylcholine in the body, is not balanced.

What is the level of the neurotransmitter acetylcholine in the body?

There are three main ways of promoting the neurotransmitter acetylcholine in the body:

liveliness;
regular physical activity;
Intellectual training.

Harchuvannya products, bagati cholin (vitamin B4) - oven (chicken, yalovicha, etc.), eggs, milk and dairy products, indichka, green leafy vegetables. Kavu is more beautiful than chaum.

If there is a lack of syruvini for the neurotransmitter virobnitstva acetylcholine, the brain will start "for itself", so follow your own rationalization.

CHARACTER DESCRIPTION "HAPPY" PEOPLE

Yogo 2 main problems:

1) chronically unsatisfied demand,

2) the unwillingness of directing his name, streaming it, and at the same time streaming it and all warm feelings, with a skin rock to shy away from it all the more and more fall into the mind: well, it’s not timid, more beautiful, not old, now. The reason is that it’s wrong to be robbed, but not the same.

If you don’t kill anything, then, at least an hour, or a human being “burned at robots”, you can help yourself more and more, and more and more; For yogo power I will go down and out, there will be unbearable hatred for myself, see the turbot about myself, in the future - see the way of self-help.

Lyudina looks like a booth;

On the smallest hopelessness, I see and I have no strength, the energy is guided by the mission.

It’s a waste of love. If you want to live, if you start, let it go: the dream will be ruined, the exchange of speech ...

It’s important to be aware - why don’t you think about it, it’s not about the deprivation of volodinnya kimos anyway. Nawpaki - in a new volodinnya deprivation, and not in the snake of the intelligence of any merriment. Let us take a look at the power of Ya. Youmu is unbearably heavy and empty: but you can't put it into words.

As soon as you know in your inventory, if you want to change, you need to read two words:

1. Vivchit of the lower guides, the text will remind and repeat it for the whole hour, as long as you don’t come to see the results of the chih new viruvan:

I am entitled to consumers. I є, і I - є I.
I give the right to demand and satisfy consumer.
I have the right to ask for satisfaction, the right to buy whatever I demand.
I give the right to greed for love and love for others.
I give the right to the organization of life.
I am giving the right to displeasure.
I have the right to be sorry and sp_vchuttya.
... by right of the people.
I can edit the video. I can be alone.
I’m going to think about myself.

I want to brutalize my readers' respect for those who do not read the text in themselves. Autotraining itself will not give any consistent results. It is important to live a skin phrase, to see, to know їy pіdtverdzhennya in life. It is important that the person wanted to believe that there could be some kind of witchcraft, and not just like that, as it would sound like that. As soon as it appears, it’s about the world and about itself in the whole world, to lay down those who have lived through life. And tsi phrases - deprive the minds of thoughts, thoughts and jokes of the powerful, new "istin".

2. Hurry up to direct the aggression against the one to whom the won is addressed to us.

... that the opportunity to see and turn to people and warm feeling appears. Obviously, it’s not ruinous, and it can be shown.

WANT TO FIND OUT WHAT IS NOT VISTACHY PEOPLE, WHAT TO BECOME SHASLIVIM?

FOR Before And every "negative emotions" LIE UP THE CONSUMPTION OF CHI SWEET, SATISFIED WITH YAKES І KEY TO ZMIN AT ZHITTY ...

FOR POSHUKU TSIKh luggage, I INVITE YOU FOR MY CONSULTATION:

SIGN UP FOR A CONSULTATION IS POSSIBLE FOR CY SUSPENSIONS:

Psychosomatic sickness (so it will be correct) - there are problems in our mind, in the basis of which there are psychological reasons. psychological reasons - all of our reactions to traumatic (folding) life experiences, our thoughts, feelings, emotions, as not to know the timeless, right for a particular people turn.

Psychic zachist spratsovuyu, we forget about the way in an hour, and sometimes it is instant, and the axis is just and unaware of the part of the psyche, all remember and give us signals at the eyes

For an hour, a call can be made to appear as if it was past the past, to see the "buried" as if they were named, for the symptom is simply symbolized by those that have been taken away.

SIGN UP FOR A CONSULTATION IS POSSIBLE FOR CY SUSPENSIONS:

Negative stress injected on human organism, and especially distress, colossal. Stress and vitality of the development of ailments is tightly interconnected. To finish telling about those who are stressed about building immunity by about 70%. Obviously, the reduction of immunity can also be beneficial. If it’s good, if it’s going to be easy colds And what about the oncological ailments of the іlіastma, which are still important?

Systematically (MSTPH) name:

2-acetoxy- N, N, N-trimethylethanaminium

power:

Chemical formula - C7H16NO + 2

Molar mass - 146.2074 g mol-1

pharmacology:

Period of the day - 2 hvilini

Acetylcholine (ACC) is an organic molecule, like the majority of organisms, including human organisms, injected like a neurotransmitter. Є a folding ester of acetic acid and choline, the chemical formula of acetylcholine is CH3COO (CH2) 2N + (CH3) 3, systematically (MSTPH) is called 2-acetoxy- N, N, N-trimethylethanaminium. Acetylcholine is one of the many neurotransmitters in the autonomic (autonomic) nervous system. Wine is infused into the peripheral nervous system (PNS), as well as into the central nervous system (CNS), and also a single neurotransmitter, so that it can be introduced into the motor form of the somatic nervous system. Acetylcholine is a head neurotransmitter in vegetative ganglia. In the heart tissue and the neurotransmis of acetylcholine in volodya igibitornyh efects, heart rhythm... On the other hand, acetylcholine is found as an anxious neurotransmitter in the neuromuscular tissues of the skeletal meat.

History history

Acetylcholine (ACH) was first introduced by Henry Hallet Dale in 1915, since it was noted that this neurotransmiter was infused into the heart tissue. Otto Levi confirmed that acetylcholine is a neurotransmitter and called it Vagusstuff (“bloody”, English). In 1936, they rejected the Nobel Prize in Physiology and Medicine for their work. Acetylcholine is the first neurotransmitter.

function

acetylcholine

abbreviation: ACH

dzherela: many

straightness: multiple

receptor: Nikotinov, muscarinic

mediator: Choline, acetyl-CoA

synthesis: Choline acetyltransferase

metabolize enzyme: acetylcholinesterase

Acetylcholine is a neurotransmitter volodya dynyu in the PNR (peripheral nervous system), and in the central nervous system. The yogi receptor may be infused with high ringing constants. In PNR, acetylcholine is active as the main neurotransmitter in the autonomic nervous system. In the central nervous system, acetylcholine simultaneously with neurons forms a system of neurotransmitters, a cholinergic system, and a type of inhibitory activity.

Have the NDP

In PNR, acetylcholine activates skeletal muscle and is the main neurotransmitter in the autonomic nervous system. Acetylcholine binds to acetylcholine receptors on the tissues of the skeletal membrane and is activated by sodium channels in the cell membrane. They penetrate the meat of the meat into a small amount of sodium, repair it in the next day, and produce it to a fast meat.

In the autonomous nervous system

In the autonomous nervous system, acetylcholine is seen:

In all postganglionic parasympathetic neurons

In all preganglionic sympathicotropic neurons

Sertsevina of the supra-nirkovo zolozi the change of sympathicotropic ganglion. When stimulated with acetylcholine, the core of the supra-nirkhovaya zolozi viroblyaє adrenaline and norepinephrine

In children of post-ganglionic sympathicotropy tissue

In neurons-stimulators of sweat zones and in the sweat zones themselves

In the central nervous systems

In the central nervous systems, acetylcholine is able to control the power of the neuromodulator and infuse it into the smoothness, activation and pediatric system. ACH plays an important role in the improvement of sensory reception before the hour, as well as ensuring respect. Post-production of cholinergic (vibrate acetylcholine) systems in the brain will lose memory when. Acetylcholine It has also been recently reported that the decline in acetylcholine may be the main cause of depression.

provinces

There are three types of guides to acetylcholine in the central nervous system

Through varolium, to the thalamus and measles to the brain

Through the large cell nucleus of the gingival nerve to measles

Septogіppokampalny way

structure

Acetylcholine is a richatomic cation. At the same time with adjacent neurons, acetylcholine establishes the neurotransmitter system, the cholinergic system, in the stem-boring part of the brain and basal vesicles forebrain, Yaka spriy widened axons in the small brain. At the stem-drill part, the brain is given a system of cobbing the ear from the pedunculopontine nucleus and the laterodorsal tegmental nucleus, which simultaneously folds the ventral tegmental region. In the basal sections of the forebrain, a system of cob is given in the basal optic nucleus of Meinert and the septal nucleus:

Prior to all, acetylcholine is an important “internal” transmiter in the striatum, which is a part of the basal nucleus. Win vivilnyaєtsya for the auxiliary cholinergic intermediate neuron.

Sensibility and Ingibuvannya

Acetylcholine volodyne and small infusions on neurons - a significant decrease in depolarization due to the additional blocking of the finely active K + struma, which increases the sensitivity of neurons. Also, acetylcholine is a healthy activator of cationic agents and such a rank does not stimulate neurons in the middle. The postsynaptic M4-muscarinic receptor for acetylcholine is brought up to the internal valve of the caloric ion channel (Kir) and produced until it is driven. Injection of acetylcholine on some types of neurons can be found in the form of triviality of holinergic stimulation. For example, a short-term assessment of acetylcholine (several seconds) can result in inhibition of cortical pyramidal neurons behind an additional muscarinic receptor, bound to the G-protein of the alpha Gq type. Activation of the M1 receptor with calcium wikid from the internal clitin pool, which, by means of activation of the energy supply, is brought into its own line by the development of pyramidal neurons. On the side, activation of the tonic receptor M1 є in the edge of the wakeful. So, injecting acetylcholine on one and the same type of receptor can be detected in the same post-synaptic neurons in the presence of triviality of receptor activation. Recent experiments on creatures have shown that cortical neurons can actually see time and persistent changes in the mussels of acetylcholine when a partner jokes. In the cerebral cortex, thin acetylcholine brings 4 balls of middle spinal neurons, and in the balls 2/3 and 5 of the balls of the middle cells. This allows the weak afferent pulsation in 4 balls and the strength of the pulsation to reach the ball 2/3 and the ball L5 of the microchains. As a result, the Danish injected acetylcholine on the ball will serve to improve the signal-to-noise performance in the brain. At the same hour, acetylcholine is infused through the nicotinic receptor and the formation of a group of inflammatory associative neurons in the cortex, so that the activity in the cortex is extinguished.

The process of taking decisions

One of the main functions of acetylcholine in the cerebral cortex is the improvement of the sensory subtlety in the form of respect. Phase improvement of acetylcholine in visual, auditory and somatosensory stimulation increased the frequency of release of neurons in adult head sensory areas measles givno to the brain. If cholinergic neurons are in the basal view of the forebrain of the enemy, the development of visual signals in animals is signi ﬁ cantly lost. When looking at the infusion of acetylcholine on the thalamocortical ligament, the transmission of sensory data, the presence of the cholinergic agonist of carbacholine in vitro on the auditory cortex of the target brain showed the increase in thalamocortical activity. In 1997, there was a decrease in the number of cholinergic agonist, and it was revealed that the activity of the bull was reduced in the thalamocardial synapses. This knowledge brought about the important role of acetylcholine in the course of transmission of information from the thalamus to the development of measles in the brain. Another function of acetylcholine in the cerebral cortex is to suppress transmission of intracortical information. In 1997, a cholinergic agonist muscarin was found to be neocortical to neocortical vertices, and a cholinergic agonist muscarin was found, and the post-synaptic potentials were altered from intracortical synapses. In vitro administration of carbacholine cholinergic agonist to the auditory cortex of mice also suppresses activity. The optical recording of the farbi's vicarious, sensitive to the springs, in the visual cortical parts showed the value of being attuned to the intracortical excitation with the presence of acetylcholine. Deyakі form navchannya and plasticity in the cerebral cortex lie in as the manifestation of acetylcholine. In 1986, a type of synaptic overgrowth in primary measles was revealed, and in the course of monocular deprivation, it decreased when cholinergic changes were made to the measles area. In 1998, it was revealed that the stimulation of the basal viddili in the forebrain, the main jerel of acetylcholine neurons, was repeated, the order with the optimized sound at the singular frequency, led to a re-generation rumor zoni measles to the brain in the side. In 1996, it was slowly infused with acetylcholine for plasticity, which is stagnant in all indications, as a way of decreasing cholinergic signals in the columnar bark of the shchuryv. In creatures with a lack of cholinergy, the decay of the weeds is significantly reduced. In 2006, it was revealed that the activation of nikotinic and muscarinic receptors in the adjacent nucleus of the brain is necessary for the administration of the plant, for such creatures they have removed it. Acetylcholine manifests itself ambiguously in vicarious tests for recent years, which is based on the functions described in the food, and the results, based on victorious tests in vicarious tests. The increase in the number of reactions in the case of correct tests and incorrect tests in primates has developed inversely with pharmacological changes in acetylcholine and surgical changes in acetylcholines. Similar dangers of bully were removed during pre-treatment, as well as when curts were taken away from the dose of nikotine (agonist acetylcholine).

Synthesis and drop

Acetylcholine is synthesized in singing neurons behind the auxiliary enzyme cholinecetransferase from stock choline and acetyl-CoA. Cholinergic neurons are responsible for the viroblasting of acetylcholine. By the attachment of the central holinergic area є the basal nucleus of Meinert in the basal form of the forebrain. The enzyme acetylcholinesterase converts acetylcholine into the inactive metabolism of choline and acetate. Daniyenzyme is superfluous in the synaptic cleavage and in the first place to enter the cleansing of the acetylcholine from the synapse, which in the region is important for the harmonious function of the mucous. Singing neurotoxins help induce acetylcholinesterase to produce an excess of acetylcholine in the neuromuscular system and paralysis of the heart.

receptor

There are two main classes of acetylcholine receptors - nikotinic acetylcholine receptors (n-cholinoreceptor) and muscarinic acetylcholine receptors (m-cholinoreceptor). The stinks were named after the ligands that activate the receptor.

H-cholinoreceptor

H-cholinoreceptors - ionotropic receptors, penetrated by sodium ions, calcium and calcium. Stimulated by nikotine and acetylcholine. Subdivided into two main types - muscle and neuronal. M'yazovy can block the curare, and the neuronal one - hexoniy. The main mice of the n-cholinoreceptor rosetting are the endometrium plates, the autonomy of the ganglion (sympathetic and parasympathetic) and the central nervous system.

nikotinov

mіasthenіya gravіs

The disease of gravity, symptoms of muscle weakness and instability, develop, if it is not a good measure of anti-nicotine receptor anti-nikotin receptors, such a rank induces the correct transmisignal acetyl. At the end of the hour, the rucous nerve plates begin to ripple into the muzzle. For the treatment of this disease, vicorist preparations are used for inguishing acetylcholinesterase - neostigmin, fizostigmin or pyridostigmin. Give the drug to the fact that the endogenous acetylcholine is better in conjunction with the other receptors before it, as it is deactivated by acetylcholinesterase in the synaptic line (the area between the nerve and the tongue).

M-cholinoreceptor

Muscarinic receptors є metabotropic and injected onto neurons for more than a trivial hour. Stimulated by muscarin and acetylcholine. Muscarinic receptor growth in the central nervous system and PNS of the heart, legends, in the upper shlunkovo-intestinal tractі sweaty vines. Acetylcholine is sometimes used during operations with cataracts for the treatment of the disease. Atropin, to take revenge in Beladon, Volodya is an antiquated effect (anticholinergic) oskilky to block m-holinoreceptors and by the very expansion of the winter, sounds on the day and like the name of the roslinist ("bella donna" for expanding the space for cosmetic purposes. In the middle of the eyes, fragments of corneal cholinesterase can be metabolized to metabolize the stagnation of muscular acetylcholine to the point of reaching the point of view. The same principle is vikorystovuyutsya for the expansion of the zinitsi, with the heart-and-legendary reanimation and in.

Recovini, which is injected into the cholinergic system

Blocking, reliance on the idea of acetylcholine is widely used in medicine. Specs are injected into the acetylcholine system, either by receptor agonists, stimulating the system, or by antagonists, attracting ї.

There are two types of nicotin receptors: Nm and Nn. Nm to be in a neuromuscular system skeletal cells through the potential of the Kintsevo plate. Nn wiklikє depolarization in the autonomous ganglion, which can lead to post-ganglionic impulse. Nicotinic receptors receive catecholamine from the cerebral ball of the supra-nirkoval corpuscles, as well as by pupils or ingibitors into the brain. І Nm, і Nn are tied with Na + and k + channels, however, Nn are tied with an additional Ca +++ channel.

Agony / antagonism of the acetylcholine receptor

Agony and antagonism of the acetylcholine receptor can be infused onto the receptor without either median or bit by bit infusion into the enzyme acetylcholinesterase, which can lead to the ligand receptor being ruined. Agony to reduce the level of activation of receptors, antagonism to reduce it.

ailing

The agony of the acetylcholine receptor is vicious for the treatment of the myasthenia of gravity and Alzheimer's ailment.

Alzheimer's ailment

The amount of acetylcholine receptors α4β2 is reduced, in the course of the development of vicious preparations, anti-inflammatory cholinoesterase, for example, galantamine hydrobromide (competitive and reversely active ingibitor).

Direct preparations The drugs described below are suitable for acetylcholine at the receptor. In small doses, the stench stimulates the receptor, in the great ones, it wicks the same.

acetyl carnitine

acetylcholine

bethanechol

carbacholine

tsevimelin

muscarine

pilocarpine

suberylcholine

suxamethoniy

іngіbіtori cholinesterazi

A large number of side-by-side agonists of the acetylcholine receptor are injected with a dose of acetylcholinesterase enzyme. Fighting, in the battery of accumulation of acetylcholine, a trivial stimulation of mucous, zalosis and central nervous system. A gift of agony with the butts of the ingibitorіv enzymіv, the stench increased the strength of the acetylcholine by way of hopefulness; They act as agents of neuro-paralytic activity (sarin, gas of neuro-paralytic activity VX) or pesticides (organophosphate and carbamate). It is clinically stagnant for malnourishment of myazovyrelaxants, for the elimination of gravitas and symptoms of Alzheimer's ailment (rivastigmine, which is a cholinergic activity in the brain).

Reversible speech

At the beginning of the speech, it is reversible to use the enzyme acetylcholinesterase (such as ruin acetylcholine), in such a rank, to increase the level of acetylcholine.

More drugs that can be used to treat Alzheimer's ailments

donepezil

rivastigmine

Edrophonia (development of masthenic and holinergic crises)

Neostigmin (ask to be vicious for the beating of neuromuscular blockers, for vicious in anesthesia, before - with the gravid disease)

Fizostigmin (vicorisation in case of glaucoma and in case of overdose of anticholinergic drugs)

Piridostigmin (in case of liquefaction of gravitas)

Carbamate insecticide (aldicarb)

Huperizin A

Non-negotiable speech

The enzyme is acetylcholinesterase.

Echotiofat

Isofluorophate

Organophosphate insecticides (malathion, Pparathion, azinphos methyl, chlorpyrifos)

Organophosphate-containing nerve agent (sarin, nerve agent gas VX)

Victims of organophosphate-containing agents in nerve-paralytic events are encouraged to go out of suffocation;

Reactivation of acetylcholine esterase

Praldoxim

Antagonism of the acetylchoin receptor

Antivomuscarinovie agents

ganglion blockers

mekamilamin

hexamethonium

trimetaphan

Neuromuscular blockers

atrakuriy

Tsisatrakuriy

Doxakuriy

Metokurin

Мівакурій

pancuroniy

rocuroniy

Sucinilholin

Tubokuranin

vecuronia

ingіbіtory synthesis

Organic mercury-containing speech, such as methyl-mercury, can cause a strong connection with sulfide groups, as well as dysfunction of choline acetyltransferase enzyme. Dana ingibuvannya can lead to acetylcholine deficiency, which can be attributed to motor function.

Ingibitories of holin reaptake

Hemikholin

іngіbіtory wikidu

Botulinum brought the wikid to acetylcholine, and the sputum of the black widow (alpha-latrotoxin) was a vicious defect. Ingibuvannya acetylcholine wiklikє paralich. With the bite of a black widow, instead of acetylcholine, it drops rapidly, and I fix it quickly. With a repeated infusion of parallich.

Insha / unidentified / unavailable

Surugatoxin

chemical synthesis

Acetylcholine, 2-acetoxy-N, N, N-trimethylene ammonium chloride, is easily synthesized from various methods. For example, 2-chloroethanol enters into the reaction with trimethylamine, and viyshov as a result of N, N, N-trimethylethyl-2-ethanolamine hydrochloride, also called choline, acetylate with andrihydroxychloride and acetyl Another method for the synthesis of polyagons is as follows: trimethylamine enters into a reaction with ethylene oxide, which, when reacted with hydrogen chloride, transforms into hydrochloride, which, in its turn, acetylates as it is already described. Acetylcholine can also be eliminated by means of the interaction of 2-chloroethanol acetate and trimethylamine.

Neuromediators play an important role in the proper functioning of the nervous system of people. One of these words, acetylcholine, is an organic molecule, the manifestation of which is characteristic of the brain of young fellows, birds and, of course, people. For the role of the neurotransmitter acetylcholine gra in the human body, why is it so important and to understand the ways of promoting acetylcholine in the body?

What is the neurotransmitter acetylcholine and its function?

The chemical formula of the neurotransmitter acetylcholine is CH3COO (CH2) 2N + (CH3). Qia organic molecule plays a role in the functioning of the central and peripheral nervous systems. Mice synthesis of acetylcholine - axons of nerve cells, speech, necessary for the formation of acetylcholine: acetyl coenzyme A and cholin (Vitamin B4). For the balance of this mediator, acetylcholinesterase (enzyme) is formed, such as superfluous acetylcholine for choline and acetate.

functions of acetylcholine

improvement of cognitive health;
polishing memory;
polypshennya nerve-muscle connection.

Deficiency of the neurotransmitter acetylcholine: causes and methods of improvement

With a change in the level of the neurotransmitter acetylcholine, acetylcholine deficiency is prevented. Precisely because of the reason for such a deficiency, it is possible for a car.

Symptoms of acetylcholine deficiency:

inability to hear;
lack of dignity is concentrated;
lack of memory of memory and information (loss of memory);
general processing of information;
fatty liver metamorphosis;
Alzheimer's ailment;
disturbed sleep;
problems with nerves;
p_advischena vtoma;
myazova weakness.

If the level of acetylcholine in the body is normalized, but it’s looking for the help of the correct harvest, it’s fired up, and the ringing between the muscles and nerves is filled with.

To the risk of lowering the level of the neurotransmitter acetylcholine to:

marathon runners and athletes who are right to show off;
people who are evil with alcohol;
vegetarians;
people, ratsion harchuvannya that are not balances.

The main bureaucrat, who has a lowered or increased acetylcholine in the body, is not balanced.

What is the level of the neurotransmitter acetylcholine in the body?

There are three main ways of promoting the neurotransmitter acetylcholine in the body:

liveliness;
regular physical activity;
Intellectual training.

Harchuvannya products, bagati cholin (vitamin B4) - oven (chicken, yalovicha, etc.), eggs, milk and dairy products, indichka, green leafy vegetables. Kavu is more beautiful than chaum. Quiet your name, your race has got enough of such products, and you can not worry about the deficiency of acetylcholine.

If there is a lack of syruvini for the neurotransmitter virobnitstva acetylcholine, the brain will start "for itself", so follow your own rationalization.

For some reason, people cannot get enough vitamin B4 from the food products, for the production of acetylcholine drugs, it is possible to indicate offensive additives and preparations:

lecithin;
citicoline;
L-alpha glitserilforsphorylchlorin;
Choline Bitartrate;
phosphatidylcholine;
Acetyl-L-carnitine (ALCAR);
racetam;
іngіbіtory acetylcholinesterase.

the site for the purpose of taking supplements and preparations for taking care of the drug for conducting specific analyzes.

First aid kit: lykarskiy dovidnik: Lykarsky preparations: Acetylcholine

Acetylcholine: describe lykarsky drug

Sinonymi

Acetylcholinum, Acetylcholine chloride, Acetylcholinum chloratum, Citocholine, Mipchol і ін.

warehouse

To be introduced to biogenic aminiv - speech, which is established in the body. To fix the drug in the quality of LZ and for pharmacological dosages, the preparation should be washed with a synthetic lining.

Acetylcholine є mono-ammonium quarters. The price is chemically unstable, it is easy to rush into organisms due to the establishment of choline and ocetic acid for the participation of the specific enzyme cholinesterase (acetylcholinesterase).

Vipusku form

Powder in ampoules of 0.1 і 0.2 m

The drug can be used without pre-treatment. Open the ampoule and inject the required amount (2-5 ml) of sterile water into it with a syringe for injection. With a boil and a trivial zberigann, it will open up.

lykuvalna diya i Shown

Statements in organism (endogenous) acetylcholine grains have an important role in the processes of life: transmission nervous excitement in the central nervous system, autonomic ganglia, the end of the parasympathetic (rukhovyh) nerves.

Acetylcholine is a chemical transmission (mediator) of nervous stimulation; the end of nerve fibers, for which wines serve as a mediator, are called cholinergic, and the receptors that interconnect with them are cholinergic receptors.

Holinoreceptors - folding protein molecules (nucleoproteins) of a tetrameric structure, localized on calling parties postsynaptic (plasma) membrane. The stench behind the nature is not uniform. Holinoreceptors, growths in the area of post-ganglionic cholinergic nerves (heart, smooth muscles, halloses) mean m-holinoreceptors (muscularly sensitive), and it is known to be found in the area of ganglionic cholinergic synapses. ). Such a subtlety is tied to the peculiarities of the reactions that occur when acetylcholine is interconnected with cymi biochemical systems, muscarinic (lower arterial vise, Bradycardia, the secretion of slug, slack, slunk, and exogenous vines, sore zinits, etc.) M- and n-cholinoreceptors are localized in the other organs and organ systems, including the central nervous system.

Muscarinic receptors have become delayed in the rest of the rock for a number of subgroups (m 1, m 2, m 3, m 4, m 5). Naybilsh vivchena in the Danish hour of localization and the role of m 1 and m 2 receptors (div.,).

Acetylcholine should not be severely vibrating on the basis of cholinoreceptors. In this chi іnshіy world wine is infused on the m- and n-cholinoreceptors and on the subgroup of m-cholinoreceptors.

Peripheral muscarinic dyu acetylcholine is manifested in the hopefulness of the heart rate, enlarged peripheral blood vessels and decreased arterial pressure, activation of the peristalsis of the slunk and intestines, fast bronchial muscles, gum sectional mikhura, Increased secretions of herbal, bronchial, persistent and sl_znykh zoloz, Zvuzhennі zinits (myosis). The remaining effect of dressing in the thickening of the fast-moving circular meat of the ridge sheath is innervated by post-ganglionic cholinergic fibers of the oculomotor nerve (n. Oculomotorius). Immediately, as a result of the rapidity of the meaty meat and the weakening of the zinc connection of the strongmeat, there is a spasm of accommodation.

Zvuzhennya zinitsi, pumovlenie dyuyu acetylcholine, supervise zvuzhennya diminished internal vice. The main effect is to explain the enlargements in the case of zoned zinitsi and flattening of the ridge shell of the Schlemm canal (venous sinus of the sclera) and fountain spaces (the space of the ridge-horned box), for the middle of which to appear inside It is not included, however, in the lowering of the internal vice to take on the role of the other mechanisms. Znizhuvati internal grip of speech, which is similar to acetylcholine (cholinomimetics, anticholinergic drugs), is widely used for treating glaucoma.

Peripheral nicotin-like activity of acetylcholine is associated with its participation in the transmission of nerve impulses from preganglionic fibers to post-ganglionic fibers in autonomic universities, as well as from nerve nerves to striated muscles. In small doses of vitamins, physiological transmission of nervous stimulation, in great doses, it is possible to reduce depolarization in the area of synapses and to block the transmission of stimulation.

Acetylcholine is also important for the role of a mediator in the central nervous system. I take part in the transmission of impulses in children to the brain, with low concentrations in the brain, and in the greats - a halmus synaptic transmission. Changes in the exchange of acetylcholine can lead to damage to the functions of the brain. Deyaki centrally-active antagonism (div.) Є psychotropic drugs (div. Takozh). Overdosing of antagonists of acetylcholine can lead to deterioration of food nervousness(Hallucinogenic effect і ін.).

sucking

For storing in medical practice and experimental acetylcholine chloride(Acetylcholini chloridum) - barn-free crystals or bila crystalline masa. Razplivayutsya on weekends. Easy to use in water and alcohol.

yak lykarskiy zasib acetylcholine chloride wide sucking not maє. When you accept it, it is ineffective in the middle, as it quickly gidrolizes. When administered parenterally, the virus has a high, sharp, ale non-trivial effect. Yak і інші quarters іnannya, nasty penetrates through the hematoencephalic bar і do not spoil the inflow into the central nervous system.

Proponated with acetylcholine corystuvatyu yak vasodinosilicate in case of spasms of peripheral vasodins (endarteritis, change of weight, trophic changes in coughs, etc.) In small vipadkas, it should be administered in case of intestinal atony and sectional microflora.

Acetylcholine is also used for the treatment of radiological diagnostics of achalasis in the stratohode.

Introduce in a dose (for older adults) 0.05 or 0.1 m Ін'єкції in times of consumption can be repeated 2-3 times a day.

Internal introduction is not allowed through the sharp decrease in the arterial vise and heart.

maximum dose for older adults: one-time - 0.1 g, dobov - 0.3 g.

Pobichna diya i Prototype

Acetylcholine contraindications for bronchial asthma, Angina pectoris, atherosclerosis, epilepsy.

In case of overdose, there may be a reduction in the decrease in the arterial vise with bradycardia and disturbed heart rhythm, profuse pith, myosis, strengthening of intestinal peristalsis and of the disease. In cich vipadkah, it is safe to inject into the vein either 1 ml of 0.1% atropin (if necessary, repeat) or a holinolytic drug (div.).

Acetylcholine (Latin Acetylcholinum) is a neurotransmitter, which is a neurotransmitter, and also the main neurotransmitter in the parasympathetic nervous system.

List of symptoms associated with acetylcholine:

attitudes
anhedonia
Problems with the concentration of respect
Missing problems
mentally
Problems with memory
low motivation
unhappiness to vispatya
Problems with solutions and vicinities of folding factories
pesimism
Feel the hopelessness and the feverishness
gratitude
slavishness
Problems with the dawn
Headache
Dryness in the mouth
Pain in the abdomen
Abdominal swelling
Diarrhea or constipation
nudota
m'yazy bill
myazova weakness
The tooth is or is slit
Pokolyuvannya abo oniminnya hands abo nig
Acceleration of the cutoff or problems with the control of the cutoff
Symptoms similar to flu or cold
Weak immunity
Cold hands and feet
Sleep problems
triviality
Yaskravi sni, in the main nightmares
Decrease in serotonin, dopamine and norepinephrine levels in the brain

Mіzh serotonіnomі acetylcholіnom іsnu vigorous antagonistic sound. If the level of one of the number of neurotransmitters grows, the level of one decreases. The amount of acetylcholine is necessary for the normal functioning of the brain. Memory, motivation, sexier sleep and sleep lie in acetylcholine. In small quantities, acetylcholine is a stimulant to dopamine and norepinephrine. Zanadto high level of acetylcholine gives the anti-aging effect, galvanizing of the central nervous system. In a child's bag, one can say that if a level of acetylcholine is moving in the brain, then there will be a decrease in some of the neuromediators, such as serotonin, dopamine and norepinephrine.

But if I am in a mood, then the combination of acetylcholine and norepinephrine, along with low serotonin, gives the result a triviality, emotional labiality, energy, pesimism, lack of pulsation, impulse If norepinephrine, dopamine and serotonin are at a low level, and acetylcholine is at a high level, the result is reversible depression. Antidepressants to the type of SSRIs, increased serotonin, increased concentration of acetylcholine, and by the very change, or aggravated symptoms, associated with increased acetylcholine. However, the main shortcomings in this approach are those who increase serotonin levels and decrease dopamine and norepinephrine levels in the brain. This is a trivial implantation of SSRIs, vreshti-resht, produced to an envious level of serotonin, and there is still one type of depression. For the very reason, SSRIs do not help all people, and in some people they can lose depression and experience unacceptable side symptoms. So, unaffected by the popularity and breadth of vikoristannya, SSRI antidepressants are not є we twist the vibrator in this vipadku.

Rivine acetylcholine in the brain without the need to accumulate in the amount of choline in the day. Ale є y іnshi reasons, like not to lie down as a result of the living. Uzha bagata holin:

Chicken eggs
sovі products
Anything to take revenge on lecithin

Deyaky people are more sensitive to the chill, so there is not a large amount of chill in living, they may have any symptoms. It is also sensitiveness to the point of being healthy.

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