Protisapalny drugs NPZP. Transfer of non-steroidal anti-inflammatory drugs

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The bile in the slopes is painful and unbearable; There are a lot of people to be especially aware of the fact that it is very important to endure the phenomenon. If you have such a problem, maybe, then you can come to help with non-steroidal anti-pyretic drugs for the treatment of suglobs. Soon you will see that they are really good people to see if they are sick.

Also non-steroidal anti-pyretic drugs

Quickly, these names are called oil refineries. To fix them drug treatment arthrosis. Protisapalny drugs are called non-steroidal because they contain no hormones. Smell be safe for the body and give a minimum side-by-side... Є Selective coatings, which are infused without a precession onto the burner, and nonselective, which also draw on the organ of the intestinal tract. Vikoristovuvati pershі perevazhnіshe.

Lіkuvannya suglobіv refinery

Give yourself an obvious sign of a drug that is associated with the intensity of the pain and the manifestation of other symptoms. Diagnosis, for which drugs can be used with NSAIDs:

• infectious, aseptic, autoimmune, gouty or rheumatoid arthritis;
• arthrosis, osteoarthritis, deformable osteoarthritis;
• osteochondrosis;
• rheumatic arthropathy: psoriasis, Bekhtur's ailment, Reiter's syndrome;
• cysts of swelling, metastases;
• bіl pislya surgical engagement, Injury.

Protisapalny preparations for suglob

In the assortment of pharmacology, you can use the following items:

• tablets;
• internal injections;
• ін'єкцій into the suglob itself;
• plastics;
• sv_chok;
• cream, ointments.

In case of important forms of ailments, slopes and self-esteem of a sick person, as a rule, signifies more strong likes... The stench will help you quickly. Go about injections in the corner. Such liquors do not poke the shlunkovo-intestinal tract. In case of more mild forms of illness, fahivets is indicated by the intake of tablets, an internal junction. Vikoristannya creams and ointments are recommended, as an addition to the complex of basic therapy.

pills

Є takі dієvі НВПС (cost):

1. "Indomethacin" (іnsha name - "Metindol"). Tablets in pain in the slopes are known to be hot, may have a fever-reducing effect. The drug p'yut two-three per day for 0.25-0.5 r
2. "Etodolak" ("Etol Fort"). Dispensed in capsules. Shvidko zebolє. Dіє on the fire burned. Yogo slide drink on one tablet 1-3 times and drink.
3. "Aceclofenac" ("Aertal", "Diklotol", "Zerodol"). An analogue of diclofenac. The drug is taken in two tablets per day. Liks are often vicious vicious effects: nudotu, zapamorochennya.
4. "Piroxicam" ("Fedin-20"). May have an antiaggregant effect, signify b_l, fever. Dose-up and rules of reception depend on the name of the car, in case of the severity of the disease.
5. Meloxicam. The tablets are priznachayutsya one or two for the sake of that, as if you have passed from the state stage before the next.

Ointment for lіkuvannya suglobіv

Classification:

1. Ibuprofen (Dolgit, Nurofen). The ointment is antiapalny that is painless for the slopes with such a main component, it will help those who have arthritis, trauma. Duzhe shvidko dіє.
2. With diclofenac ("Voltaren", "Diklak", "Diclofenac", "Doklevoyut"). so lykarsky ointments rozіgrіvayut, know more views and block ignition processes. Shvidko will help the team to whom it is important to collapse.
3. With ketoprofen (Ketonal, Fastum, Ketoprofen Vramed). Pereshkozhayut approved blood clots. When zanadto trivial zasosuvannі ointments can appear visip on tіlі.
4. With indomethacin ("Indomethacin Sopharma", "Indovazin"). The diet is analogous to the drugs based on ketoprofen, but intensively. Good morning, additional help when rheumatoid arthritis, Gout.
5. With proxycam ("Finalgel"). Know ailing symptoms, do not dry the shkiru.

pricks

Vidіlyayut such refinery preparations for ін'єкцій:

1. Diclofenac. Knowing zapalennya, b_l, is recognized when ill with an important form. Intrashnyom'yazovo inject 0.75 g of the drug one or two times for doba.
2. "Tenoxicam" ("Texamen L"). Razchinniy powder for ін'єкцій. 2 ml for doba priznachayut with not very severe pain syndrome. The dose is increased and given a five-day course for gouty arthritis.
3. "Lornoxicam" ("Larfix", "Lorak"). At m'az anyway vein inject 8 mg of the drug once or twice a day.

New generation prototypical non-steroidal drugs

More successful, and more effective:

1. "Movalis" ("Mirloks", "Artrozan"). An even more effective drug, which is dispensed with pills, injection for injections, candles. Practically not yes side effects... For pricks of vicoristovy, 1-2 ml of a dose for doba. Take 7.5 mg tablets once or twice a day.
2. Celecoxib. Not greasy injected onto the slurry. Take one or two tablets for dob, or not more than 0.4 g of the drug per day.
3. "Arcoksia". The drug is in tablets. Dozuvannya priznachayut in the fallowness of the severity of the ailment.
4. "Nimesulid". It is dispensed in tablets, sachets for dilution, in gel form. The dose is determined by the drug, as well as the rules for taking.

Refinery on the current day in a dynamic class drugs... The price is tied to a wide range of storage of a given pharmaceutical group, yak volodya, fever-lowering and analgesic activity.

NPZP - tsila group of drugs

NPZP block the enzyme cyclooxygenase (COX), which induces the synthesis of prostaglandins from arachidonic acid. Prostaglandins in organisms are fired by mediators, reduce the threshold of sensitivity to pain, galvanize peroxidation of lipids and galvanize aggregation of neutrophils.
Prior to the main improvements of the refinery include:

• Protisapalny. Attract the exudative phase of ignition, і, in the smallest world, proliferative. Diclofenac, endometacin is the most powerful drug for this drug. Alle protisapalnu dіyu mensh is rotated, lower in glucocorticosteroids.
  Practical lactation of the classification, but also of all the oil refineries should be used to: There is a large number of different drugs for the whole group. Low anti-firing activity may be Paracetamol, Metamizole, Ketorolac and deyaki іnshі. The group is innumerable.
• Bolezaspokilivy. Nibilsh bends in Diclofenac, ketoralak, metamizole, Ketaprofen. Vikoristovyuat with pains of low and medium intensity: teeth, meat, head. Effective with nirkovy number, that is why. In patients with narcotic analgesics (morphine group), do not hesitate to drive them to the dyshal center, do not wick.
• Heat-resistant. All drugs in the development world are given by the authorities. Ale will come out only with the manifestation of a feverish woman.
• Antiaggregation. Show up for the synthesis of thromboxane. Nybіlsh bends tsei efekt at Aspirinu.
• Immunosuppressive. Appear suddenly, for the rakhunok of the penetration of the capillary walls.

Shown before the oil refinery

Prior to the main indications, follow:

• Rheumatic illnesses. Include rheumatism, rheumatoid arthritis, Bekhtur's ailments, gouty psoriatic arthritis, Khvoroba Reiter. In case of diversification of the disease, the use of NPZP should be symptomatic, not influencing the pathogenesis. To ensure the development of a destructive process in rheumatoid arthritis, there is no way to prevent deformity of the joints in the intake of drugs in a group of refineries. Ale skargi patsієntіv on bіl, skutіst in the slopes on cob stages get sick more.
• Ailments of the musculoskeletal apparatus of a non-rheumatic nature. Suddenly with injuries (blows, stretching), musitis, tenosity. When you get overwhelmed, you get sick and stop the oil refinery in the middle, at the viglyadі ін'єкцій. First, the most effective calls are made (ointments, creams, gels), which can be used in their warehouse for the various speeches of the group.
• Neurological illness. Lumbago, radiculitis, mіalgії. Often, a combination of different forms of a drug release (ointment and tablets, іn'ktsії and gel, etc.)
• Nirkov ,. The preparations of the NPZZ group are effective for all types of rings, so that they do not suffer from pre-inferior spasm of smooth cell membranes.
• pain symptoms developmental ethology... Pain relief during the operational period, Tooth i head bill.
• Dysmenorrhea. NPZP stasis for relief of pain syndrome in case of primary dysmenorrhea and for reduction of blood loss. Naproxen, Ibuprofen is a good effect, which is recommended to take one menstrual period and three days in advance. Such short-hour courses will remember the appearance of unfavorable effects.
• Lichomaniac. Fever-lowering preparations are recommended to be taken at temperatures below 38.5 ° C.
• Prevention of thrombosis. For the prevention of the setting of thrombi Acetylsalicylic acid in low dosage. It is used for the prevention of infarctions, strokes with different forms ischemic ailments of the heart.

Negative effects and contraindications

Preparations of a group of non-steroidal anti-inflammatory agents to repair a negative infusion on:

1. and intestines
2. pechinka
3. nirki
4. shelter
5. nervous system

Naybils are often found in the reception of non-steroidal anti-fiery suckers. Manifest the price of tediousness, pain, pain in epigastric pain and dyspeptic scarg. To create such a syndrome - the refinery-gastropathy, the diagnosis of which is directly linked to the reception of the refinery. Especially sick to the risk of pathology of the patient of the kidnapped veterinarian, because of the presence of a slunk in the anamnesis, as they take glucocorticosteroids at once.

Oil refinery plant - ізні preparations, ale їkh dіya one!

Immovability of the development of refinery-gastropathy of growth with trivial intake of drugs in high doses, as well as with the intake of two or more refineries. For the removal of the mucous slurry, use Lansoprazole, Esomeprazole and інші іngіbіtory proton pump. may be in the presence of an important toxic hepatitis, and may be manifested by past impaired functions due to the growth of transaminases in the blood.

The furnace is most often used for taking endometacin, phenylbutazone, and Aspirin. On the side of nirok, there can be a decrease in dyuresu, gostra nirkova lack, Nephrotic syndrome, which is the result of striking nirok tubules. Nybilsha needs to become Ibuprofen, Naproxen.

In the blood, there is a deterioration in the processes of the throat, anemia. Diclofenac, Piroxicam, Butadion are not safe from the side of the blood system. Often, there is no need for an effect on the side of the nervous system and is found when taking Aspirin, Indometacin. І manifests itself as headache, noise in vuhah, tediousness, and inodi and blues, psychotic... Acceptance of the oil refinery plant of contraindications in times:

• abo intestines
• Vigor and during the period of the year
• Symptoms of bronchial asthma
• Epilepsy, Parkinsonism, Psychic Disorders
• Hemorrhagic diseases, thrombocytopenias
• Arterial hypertension and heart failure (not all drug groups)
• Individual intolerance to lykarsky zasob

It is practical to use oil refineries in all areas of medicine. Tse is tied with їх numerical effects: anti-fiery, fever-lowering and anti-sickness. The oil refinery plant lays down the citizens of the patients with all kinds of symptoms, shrinking the quality of life and giving the standard of comfort.

Aspirin is a representative of the group of non-steroidal anti-fiery species. About yogo і skoda for the body of people in video materials:

telegram

At the same time I read the following article:

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  Yak і chim lіkuvati pіdshlunkovu zalozu, complex pіdhіd s ...
• 
  

Protistopal nonsteroidal drugs (NPZP, NPZP) are a new generation of medicinal preparations, such as antihepatic, fever-lowering and anti-inflammatory (analgesic) effect. The mechanism of pouring in is primed on the blocking of singing enzymes (cyclooxygenase, COX), which are considered for the approval of prostaglandins - cheeky words, so they take a lot of visions, get lukewarm.

The word “non-steroidal”, which is in the name of cich drugs, is indicative of the fact that the medicinal preparations of this group are not single-piece analogs of steroid hormones - the most necessary anti-festering hormonal agents. By the most popular representatives of the refinery є diclofenac, ibuprofen.

The Robotic Refinery Principle

If analgesics are used to combat pain, then the NPZP is reduced by two unacceptable symptom ailments: burned and bil. A lot of drugs in the whole group are infused with non-selective inhibitors of the cyclooxygenase enzyme, which can be used for both of these isoforms (species) - COX-1 and COX-2.

Cyclooxygenase is responsible for the knowledge of arachidonic acid and thromboxane and prostaglandins, which, in their turn, go to phospholipids in the cell membrane for the auxiliary enzyme phospholipase A2. Among the main functions of the prostaglandin are regulators and in between in the lighting.

If you want to use oil refineries?

Most of the drugs NPZP vikoristovoyt for likuvannya chronic chi gostry zapalennya, I have a feeling of pain. The great popularity of anti-combustion nonsteroidal drugs was eliminated effective treatment suglob_v.

Pererakhumo ailments, when you prescribe a medical problem:

Refinery fences vikoristovuvati per hour erosive-virazkovyh lesion of the shlunkovo-intestinal tract, Tim more, at the stage of aggravation, cytopenia, rotations of robotic destructions, liver disease, vaginosity, individual intolerance. Zobovyazany with protection is recognized for patients with asthma, as well as for people who have had negative reactions before any hour at any refinery.

Non-steroidal anti-pyretic drugs: a list of oil refineries for the treatment of suglobids

It is easy to understand the most effective and type of oil refinery, which can be used for the treatment of loams and in the case of those who are ill, if necessary febrile and anti-fiery effect:

Deyakі medicinіlіki weak, not so agressive, deyakі rozrahovanі on gostry arthrosis, as it is necessary to be extraneous in hand, so that zupiniti in organism is not safe processes.

The main transshipment of the new generation oil refinery

Some of the effects are determined by the hour of the trivial recovery of the oil refinery (for example, by the hour of the treatment of osteochondrosis) and are stored in the damaged intestinal mucosa and the drain from happy bleeding and virazok... Daniy doesn’t use the oil refinery indiscriminately injecting it as the reason for the development of the new generation of drugs, as it blocks the COX-2 (fermenting enzyme) and doesn’t infuse on the COX-1 function (the enzyme zakistu).

So, the preparations of the new generation may not be susceptible to secondary ulcerogenic effects (reduction of the mucous organs of the herbal system), which are tied to nonselective refractory products, which will give a greater chance of thrombotic acceleration.

With the minus drugs of the new generation, you can see a lot of options, so that they are inaccessible to the majority of people.

What about a new generation oil refinery?

Protistopalny non-steroidal drugs of the new generation are injected over the top, the stench of a big world іngіbuyut COG-2 Moreover, COG-1 will be overlaid with mayzhe nezaplenim. The cym itself can be explained to increase the efficiency of the drug in a given minimum side effects.

List of effective and popular anti-fiery non-steroids new generation:

• Ksefokam. Lykarskiy zasib, based on lornoxicam. yogo characteristic featureє the fact that the drug can be adjusted to the health of the patient. For the given indicator of wine, analogous to morphine, but at the same hour I do not open the sound and do not attack the central nervous system with an opiate-like injection.
• Movilos. There is a heat-reducing, kindly bending anti-fiery і zealous effect. The main reason for the transformation of the drug given to the drug lies in the fact that, with a constant visualization of the drug, it can be victorious to finish a trivial hour. Prepare meloxicam in a form for internal injections, in ointments, suppositories and tablets. Drain the pills to the drug with a quick dose of trivial smell, and take one pill for a day.
• Nimesulid. Successfully vicarious for treating arthritis, vertebral sickly visions in spin i etc. Normalizes the temperature, recognizes the temperature and the ignition. By taking the drug, it can be quickly brought to the point of complete collapse and pain relief. It is also stagnant in the form of ointment for application to the problem area.
• Celecoxib. The Danish drug is a hundred and fifty years old for a patient with arthrosis, osteochondrosis and other ailments, it effectively fights against inflammation and is known to have a pain syndrome. Pobichna diya on the system of etching from the side to the preparation is minimally or increase in the daytime.

In vipads, if they do not require a trivial intake of anti-inflammatory non-steroidal drugs, then vikoristovuyut drugs of the old generation. However, it’s just because we’re impelled by the call, as not all people can afford the course.

Classification of refinery

For chemistry, the drugs are not acidic and acidic.

Acid preparations:

Non-acidic preparations:

• Like sulfonamide;
• Alcanoni.

With a wide range of non-steroidal drugs, they are classified according to the intensity of the type of drug - antiapalnic, analgesic, combined.

For the strength of the antiapalis The average doses of the drug are rosted in the following end (the top is the strongest):

• flurbiprofen;
• indomethacin;
• piroxicam;
• Diclofenac sodium;
• naproxen;
• ketoprofen;
• aspirin;
• amidopyrine;
• Ibuprofen.

For analgesic injection the preparations are roasted in the following design:

Most of the time, the refinery is overhauled, the preparations become stagnant. with chronic i gostrich hvorobakh , Yak, supervodzhuyutsya hot and pain. As a rule, anti-inflammatory non-steroidal medications are used for the treatment of loam and pain relief: for eliminating injuries, arthrosis, arthritis, etc.

Often the oil refineries are stagnant for pain in case of migraines and headaches, nirkovy rings, Pislyaoperative pains, dysmenorrhea, etc. For rakhunok galmyuchogo diy on the synthesis of prostaglandins, given the drug, it also produces a fever-lowering effect.

vibir dozuvannya

Be it new for a patient, it is necessary to recognize the combination in the smallest dose. With normal portability through a few days daily dose increase.

Therapeutic dosage of the refinery is located in the great range, at the same time, there is a tendency to increase the dosage of one-time and additional doses, so that there is an increase in the tolerance of maximum For children lіkuvalnu dіu to reach the deprivation with vicarystann_advizhennyh doses of the refinery.

bitter appearances

Trivale vikorystannya of anti-fiery lakes in subdivided doses, you can viclicati:

Likuvannya Oil Refinery Plant in the least possible hour and in the smallest doses.

Vikoristannya with vaginosti

Negligently vikoristovuvati in case of vaginosis of the preparation of a group of non-steroidal anti-fatigues, more in the third trimester. If I want to avoid teratogenic effects without appearing, to get involved, the oil refinery can help the fetus to get sick and early on the clotting of the arterial duct. There is also information about the front canopy. Uninvolved on the price, aspirin in combination with heparin is successfully vicious in women with antiphospholipid syndrome.

Description of non-steroidal anti-inflammatory drugs

movilia

є leader the middle of non-steroidal anti-pyretic drugs, which takes an hour and a half of permissions to a trivial vicorian.

I can develop an anti-firing effect, which gives the possibility of being vicious with rheumatoid arthritis, ankylosing spondylitis, osteoarthritis. Zakhischaє cartilage tissue, not the addition of heat-sensitive and anti-fire powers. Vikoristovutsya with headache and toothache.

Dose assignments, options for taking (suppositories, injections, pills) should be stored according to the type and severity of the ailment.

celecoxib

Engіbіtor COG-2 sun-sick and anti-fiery diyu... With vicorian in therapeutic doses, negative action on the mucus of the intestinal tract should not be damaged, so it’s possible to reach COG-1 with a low level of spore, apparently, not impairing the synthesis of constitutive prostaginous.

indomethacin

Submitted before effective drugs non-hormonal injected. In case of arthritis, I reduce the thickening of loams, I know more and more strongly against the fire. When victorious medical zasobu is required to be accurate, there is a great list of vicious appearances. In pharmacology, the drug is prepared under the names Indovis ЄC, Indovazin, Indokollir, Indotard, Metindol.

ibuprofen

I also have the ability to effectively reduce the temperature and the temperature. likarski zasobi it can be bought without a prescription. Ibuprofen in the role of a febrile drug vicious, including i for new women.

As a protivopalny drug, it does not often take a toll, proteics are even more popular in rheumatology: it can be used for treating osteoarthritis, rheumatoid arthritis and other ailments of loam.

Before the most popular names are Nurofen, Ibuprom, MIG 400 і200.

diclofenac

Form of preparation - capsules, tablets, gel, suppositories, solutions for ін'єкцій. V given drug For the removal of slopes, it is obvious to admit that it has a high anti-firing effect, as well as pain-relieving activity.

You can use the names Naklofen, Voltaren, Diklak, Ortofen, Vourdon, Diklonak P, DOLEX, Olfen, Klodifen, Dikloberl etc.

Chondroprotectors - alternative drugs

Even more often for lіkuvannya suglobіv vikoristovuyt chondroprotectors... People are often not aware of the fact that they are chondroprotectors or refineries. The rest of us quickly see more visions, but at the same hour, we see a lot of unpredictable appearances. And the chondroprotectors are able to seize the tissue of cartilage, but it is necessary to live them in courses. The warehouse of the most effective chondroprotectors has two words - chondroitin and glucosamine.

Protistopalny nonsteroidal drugs є by the ministers from the hour to get sick. Alle, it is necessary not to forget, but to clean up the stench negatively, to infuse symptoms on self-feeling, to treat ailments without the need to be carried out in the same ways and with drugs.

Non-steroidal anti-pyretic drugs, which are shortly called oil refineries, or oil refineries (most) are widely stagnated in the world. In the United States, the statistics have blown away all the galuzy of life, they have fucked up, so that the skin of American consumers is given more than 70 million recipes at the refinery. American vip, prick and smear on skins for more than 30 milliard doses of non-steroidal anti-pyretic drugs in rick. It is unlikely that our spyvitchizniki will be seen from them.

With all the popularity, the large number of oil refineries is based on a high level of non-baking and low toxicity. Navi at high doses of acceleration in the region of maloimovirnі. Well, why are you for the miracle?

Non-steroidal anti-flue gasps - there is a large group of people, as they have three effects at once:

• sun-sick;
• fever-lowering;
• to the prototype.

The term "non-steroid" is a reference to steroids, to hormonal drugs, which can also be used as an anti-fatigue.

The power, evidently seen by the refineries of the middle analgesics, is the appearance of the sound in case of trivial consumption.

Excursion to history

The "root" of non-steroidal anti-inflammatory drugs is far away. Hippocrates, is alive at 460-377 rr. until our time, having seen about vicorian measles willow for zebooluvannya. Trochi piznishe, in the 30s BC Celsius confirming his word and stating that the bark of the willow wonderfully pom'yakshu signs of burning.

The riddle about the analgesic bark is coming to a head in 1763. First, in 1827, the chemists were able to see from the willow extract that speech itself, which became famous for the hours of Hippocrates. Active ingredin from verby measles emerged with the glycoside Salicin - an alternator of non-steroidal antiapaline spirits. In 1.5 kg of measles, 30 g of purified salicin were trimmed.

In 1869, for the first time, they were more effective than salicin - salicylic acid... I was unhappy, I won’t be able to slime the slurry, and at the beginning of the day there was an active shout of new speeches. In 1897, the Nimetsky chemist Felix Hoffman and the Bayer company introduced a new era in pharmacology, zoomed in to convert the toxic salicylic acid into acetylsalicylic acid, and I called it Aspirin.

For a long time, aspirin became the first and only representative of the group of non-steroidal anti-fiery animals. Since 1950, pharmacologists have begun to synthesize all new drugs, which are more effective and better than before.

Yak to run an oil refinery?

Non-steroidal anti-fumes help to block the release of words, which are called prostaglandins. The stench is to take a bezposrednyu fate from the development of pain, fever, fever, mazovyh court. Most NPZP nonselectively (nonvibirkovu) block two other enzymes, which are necessary for prostaglandin to virobrate. The stench is called cyclooxygenase - COX-1 and COX-2.

The prototype of the non-steroidal prototype of the fire is rich in what is reasoned:

• changes in the penetration of the vessels and the microcirculation in them;
• Decrease in vivilnennya from the clerk of special speeches, which stimulate fieryness, - mediators fired.

Moreover, the oil refinery is blocking the energy processes in the middle of firing, and by itself amusingly “firing”. Analgetic (zealous) development develops as a result of a change in the ignition process.

serious undersized

It's time to talk about one of the most important minuses of non-steroidal anti-inflammatory drugs. On the right, in the fact that COG-1 has a positive role in viroblastic prostaglandins. Win takes a part in the synthesis of prostaglandin, which is a reversal of mucous slurry under the influence of hydrochloric acid. If you do not vibrate іngіbіtori COG-1 and COG-2 fix the potsyuvati, the stench will increase blocking prostaglandins - і "shkіdlivі", so wicked fired up, і "corisnі", so hijack the slunk. So non-steroidal antiapaline liquors provoke the development of twisted ailments of the slunk and two-fingered intestines, as well as internal bleeding.

Ale the middle of the family of refineries and special preparations. The price of the most efficient tablets, which is the vibrating blocking of COG-2. Cyclooxygenase type 2 is an enzyme that takes care of the fate only in igniting and not having any additional preservation. To that end, the blockade will not be clogged with unacceptable inheritances. selective blockers COG-2 does not provoke intestinal problems and is caused by more high-grade baked goods, lower than others.

Non-steroidal anti-fumes and fever

NPZP will be absolutely unique in power, as it sees in the middle of the preparations. The stench is nadayut hot-blooded diyu and can be used for licking a feverish woman. It’s bright, as it smells like it’s good quality, it’s later that the temperature rises.

Lichomaniac develops in the form of an increase in prostaglandin E2, which is the name for the swiftness of the shooting neurons (activity) in the boundaries of the hypothalamus. And the hypothalamus itself is a small area in to the brain- and control of thermoregulation.

Fever-lowering non-steroidal anti-pyretic drugs, which are called antipyretics, and the enzyme COX. It can lead to galvanization of prostaglandin, as a result of galvanization of neuronal activity in the hypothalamus.

Prior to the speech, it was established that the most powerful turns of the heat-resistant powers of Volodya Ibuprofen. Winning has overturned paracetamol as its closest competitor.

Classification of non-steroidal anti-inflammatory drugs

And now, let's try to get back, as we must admit to the non-steroidal anti-fiery spirits.

On the current year, there are dozens of drugs in the whole group, but not all of them are registered in Russia. There are only those types of liquids that can be bought at local pharmacies. The refinery is classified according to its chemical structure and mechanism of development. It’s not easy to read the reader with folding terms, induced by forgiveness of the classifications, in any case, if you want to name them.

Otzhe, the entire list of non-steroidal anti-combustion devices is added to the pod group.

salicylates

The group itself has been nominated, and the history of the refinery has been repaired. Single salicylate, which is stagnant and synonymous, is acetylsalicylic acid, or Aspirin.

Acid propionic acid

Prior to them, one of the most popular non-steroidal antiapalny drugs, zokrema preparations, are mentioned:

• ibuprofen;
• naproxen;
• ketoprofen і deyaki іnshі lіki.

Acid ocetic acid

Not less famous and other-lost ocetic acids: indomethacin, ketorolac, diclofenac, aceclofenac and іnshі.

Selective Ingibitories COG-2

Prior to the safest non-steroidal anti-inflammatory drugs, these new drugs should be administered last generation Alle, only two of them have been registered in Russia. Remember їх international name- cecelecoxib and rofecoxib.

Інші non-steroidal prototypes

The okremі pіdgroup includes piroxicam, meloxicam, mefenamic acid, nimesulide.

Paracetamol is even weakly protivopalny activity. The head of the VIN block COG-2 in the central nervous systemsі nadaє zealous, as well as pomirniy heat-negative effect.

If the oil refinery is stagnant?

As a rule, the oil refinery is stuck for a drink chronic heat, Suprovodzhuvanogo pain.

Excessively ill, when stagnant non-steroidal antiapaline drugs:

• arthrosis;
• pomyrnі pain through burning or injuries of soft tissues;
• osteochondrosis;
• b_l across;
• head b_l;
• gostra gout;
• dysmenorrhea (menstrual pain);
• pain in the cysts, wicclicans with metastases;
• pislyaoperating pains;
• I am in pain with Parkinson's ailments;
• fever (increased temperature);
• intestinal imperfection;
• nirkova kolka.

In addition, non-steroidal anti-fiery canals are stagnant for children, some arterial ducts do not curl up for 24 years.

Tsey divovizhniy aspirin!

Aspirin can be easily brought to the preparation, so that the whole light has been preserved. The most extraordinary non-steroidal anti-pyretic tablets, which were used for lowering the temperature and reducing the temperature, demonstrated a non-standard side effect. Viyavilosya, scho, blocking COX-1, aspirin at the same time halmє synthesis of thromboxane A2 - speech, yak zbіlshu sgortania blood. Aspirin is allowed to be injected into the blood viscosity. However, for mіlyonіv ailments for hypertensive ailments, Angina pectoris, ischemic ailment the hearts and minds of the heart-and-judgmental sickness of the sutta. For them, it is more important that aspirin in low doses helps to prevent heart-and-heart catastrophe - infarction and stroke.

Most people recommend taking aspirin to prevent myocardial infarction and insult in cardiological, low doses to people in 45-79 patients and women - 55-79 years old. The dose of aspirin is adjusted according to the drug: as a rule, it should be taken from 100 to 300 mg per dose.

Kilka rokiv that vcheni viyavili, who aspirin lower the zalny rizik development cancer patients and mortality from them. Rectal cancer is especially effective. American patients recommend that their patients take aspirin to prevent the development of colorectal cancer. On ёkhnyu dumka, risik development of side effects in the case of trivial treatment with aspirin is still lower, not oncological. Before we speak, let us be cognizant of the side effects of non-steroidal anti-fiery fires in our neighbors.

Heart rhizics of non-steroidal anti-inflammatory drugs

Aspirin, with its antiaggregant effect, vibrates from a string of siblings in a group. It is important to have a large number of non-steroidal anti-fatigues, including the occasional COG-2 ingibitoria, to promote the development of myocardial infarction and insult. Cardiologists, as well as patients, have recently experienced a heart attack, they need to be reconsidered from the refinery's history. According to the statistics, the victoriousness of the cich likiv mayzhe in 10 times the increase in the development unstable angina... It is a good idea to use naproxen from the point of view of the naproxen.

On April 9, 2015, the FDA published an official policy for the FDA. A new person is going to know about the admission of risk of insult and infarction in ailments who are stagnant to nonsteroidal anti-fatigue. Zrozumilo, aspirin is a happy vignatok from the axiomi community.

Injection of non-steroidal anti-combustion on the slunk

Another vidomy side effect of the refinery is shlunkovo-intestinal. We have already spoken, so win the dressing with tight ties pharmacological of all non-vibrating іngіbіtorіv COG-1 and COG-2. However, the oil refinery does not only reduce the level of prostaglandins, and they themselves release the slime of the slurry to the sink. Molecules appear and behave aggressively in relation to mucous membranes shlunkovo-intestinal tract.

Nudota, bloating, dyspepsia, diarrhea, fever ailment, including bleeding, may occur on a lingering non-steroidal anti-pyretic disease. The slurry-intestinal side effects of the refinery are developing right away because of the fact that they were consumed by the body: oral in the eyes of the tablets, injections in the eyes and rectal in the eyes of the pigs.

Chim is more than trivially lіkuvannya and chim more than the dosage of oil refineries, thym vishche risik to the development of twisted ailments. In order to increase the efficiency of the diagnosis to the minimum, you can take the lowest effective dose with a stretch of the shortest period.

Recently, it was shown that more than 50% of people use non-steroidal anti-burners, slizova small intestine all the same poshkodzhutsya.

It is obvious that the preparations of a group of non-steroidal anti-pyretic agents are poured onto the slime of the slurry in a different way. So, indomethacin, ketoprofen and piroxicam are most important for the intestine and intestines. And up to the number of the most not-for-great, ibuprofen and diclofenac are introduced.

Okremo would like to say about intestinal-corrosive shells, how to use non-steroidal anti-pyretic tablets. Wyrobniks start dying, so it is also possible to help you to reduce the risk of lowering or lowering the level of niveluvati risik shlunkovo-intestinal accelerated oil refineries. However, the message key practice to show that for the sake of reason such a zajist is not successful. The more effective efficiency of the slime slurry rate decreases the one-hour intake of liquids, which block the hydrochloric acid release. Ingibitories of proton pump - omeprazole, lansoprazole, esomeprazole and іnshі - good food for the preparation of high-quality drugs for a group of non-steroidal anti-apalagines.

Say a word about citramon ...

Tsitramon is a bred brain storm of Radiansk pharmacologists. Far away, since the assortment of our pharmacies is not numbered with thousands of drugs, pharmaceuticals have come up with a miraculous formula for an analgesic-antipyretic. The stinks were given "in one bottle" a complex of non-steroidal anti-pyretic drugs, antipyretics and seasoned with a combination of coffee.

Vinahid viyavivsya deeper in the distance. skin diyucha speech did one to one. Suchasn_ pharmaceuticals have changed the traditional prescriptions, replacing the antipyretic phenacetin with non-baked paracetamol. In addition, from the old version of citramone, they used cocoa and citric acid - citric acid; The drug of the XXI century is to take away aspirin 0.24 g, paracetamol 0.18 g, and coffee 0.03 m and without affecting trophies of changes, everything is so self-help in terms of pain.

However, unaffected by an affordable price and even higher efficiency, Citramon has its majestic skeleton in Shafi. Likars have long been in the process of doing this and have brought me to the bottom of the mucous membrane of the intestinal tract. Seriously, navilki, so in the literature to find the term "tsitramonovaya virazka".

The reason for this obvious aggression is simple: I want to give Aspirin an active drink, which stimulates the production of hydrochloric acid. As a result, the mucous membrane of the slunk was lost without prostaglandin clogging. Moreover, it’s not only when you see it at home, it’s like it and it’s right, but it’s all at once, when the citramon is soaked into the roof.

Dodamo, scho "tsitramonovye" great sizes... Some stinks do not "grow up" to gigantic ones, but take a few stinks in groups in different types of slurry.

The moral of this step is simple: do not try to use citramone, unimpressed on all of your passions. It is also important to have inheritance.

Refinery and ... sex

In 2005, there were a lot of unacceptable side effects of non-steroidal anti-fiery fires in the belongings. The financial events held a pre-session, which showed that the triviality of the oil refinery plant (on 3 months) increased the risk of recurrent dysfunction. Nagadaєmo, as a matter of fact, may be on the view of the ruin of the erection, among the people called the empowerment. Todi urologists and andrologists were interested in no less high-quality experiment: injecting leaks into the sexual function of the assessed only on the presentation of special perceptions of the person and not overturning the faults.

However, in 2011, the authoritative "Journal of Urology" has published the tribute of one more recent report. At the new one, there was also a chime in between the licks of the non-steroidal anti-fiery fires and the destruction of the erectia. Protect, likarі, ryzhuyut, and the residuals are still injected early. And as soon as vchenі is engaged in a fuss of proofs, the choloviks are still more beautifully using non-steroidal protivopalny drugs.

Інші secondary efficiency refineries

With serious inappropriateness, such as blocking up the drink with non-steroidal anti-fiery zasob, we were confused. Let's move on to expand the unfriendly podіyam.

Damaged function of nirok

Acceptance of oil-and-gas production of dressings і from a fairly high level of nirkovy side effects. Prostaglandins take a part in expanded blood vessels in nirk glomeruli, allowing normal filtration in nirkas. If the prostaglandins fall, - and the whole effect is based on the action of non-steroidal anti-firing devices - the robot can never be damaged.

To the most risky of nirk side effects, very well, people are sick because of nirok.

photosensitivity

To achieve often trivial lіkuvannya non-steroidal anti-fiery means of superfluousness. It is worth noting that piroxicam and diclofenac are more due to the unfortunate effect.

People who take antiapaline drugs can react to sleepy changes in their child's heart, and in any case, with their own childish reactions.

hypersensitivity reactions

Non-steroidal anti-fiery "glorified" and allergic reactions. The stench can be manifested by visip, svitlochutlivistyu, sverbіzh, kvіnke quilting and anaphylactic shock. True, the last effect is borne out to the number of children in the region, and this is not the fault of potential patients.

In addition, taking NPZP can lead to headaches, blockages, drowsiness, bronchospasm. Zrіdka ibuprofen wiklikє syndrome of irritated bowels.

Non-steroidal anti-fatigue in case of vaginosis

To deliver often in front of the women of the hospitality of the food supply. What is it possible for mothers to be able to fix oil refineries? It’s a pity it’s dumb.

Unimportant to those preparations of a group of non-steroidal anti-inflammatory drugs, do not affect teratogenic children, so as not to suffer gross vices in the development of a child, we can still smell the naughty one.

So, there are the facts, like talking about the possible completion of the closure of the arterial duct in the fetus, when the mother has taken the refinery for an hour. In addition, deyakі until lіdzhennya show the sound between the reception of the oil refinery and the front canopies.

Protect the drug is still vicious during vaginosis. Napriklad, Aspіrin often priznachayut time of heparin zhіnkam have yakih pid hour vagіtnostі boule viyavlenі antifosfolіpіdnі antitіla. The popularity of endometacin will remain especially popular for the treatment of pathologies of vaginosity by adding old age and endomethacin. Yogo began to be stashed in obstetrics in case of abundant water supply and a threat to the front canopy. However, the French Ministry of Health has seen an official mandate for the protection of non-steroidal anti-fatigues, including aspirin, for a great month of vaginosity.

Refinery: accept chi vіdmovitiya?

If there is a need for a refinery, but if there is a need to see it from them? Let's see all the possible situations.

Refinery in individuals

We also know the strengths and weaknesses of the refinery. And now, let’s spare it, as antiapalny preparations are more beautiful than stasis for pain, as for burning, and as for when temperature and cold.

Acetylsalicylic acid

The first oil refinery, which after pumping light, acetylsalicylic acid, is widely used to accumulate to qix pir. As a rule, її stasis:

• for lowering the temperature of til.

  Beastly respect that acetylsalicylic acid is not recognized for children under 15 years old. It is tied with tim vyrusnyh zhvoryuvan the drug signifies the development of Rey's syndrome - birthright pechinki, which do not pose a threat to life.

  matured acetylsalicylic acid and fever-reducing should become 500 mg. The tablets are taken only at an increased temperature.

• as an antiplatelet agent for the prevention of heart-and-vascular disasters. The dose of cardioaspirin can be adjusted from 75 mg to 300 mg per dob.

You can buy acetylsalicylic acid from the fever-lowering dose under the names Aspirin (vyrobnik and owner of the brand name of the nimetska corporation Bayur). Vіtchiznyany enterprises produce even less inexpensive tablets, as they are called - Acetylsalicylic acid. Besides, the French company Bristol Mayers viroblyaє effervescent tablets Upsarin Oops.

Cardioaspirin maє bezlich names and forms of vipusku, including Aspirin Cardio, Aspinat, Aspikor, CardiASK, Trombo ASS and іnshi.

ibuprofen

Ibuprofen is single-use in its own safety and the ability to effectively reduce the temperature and volume, so the preparations on this basis are sold without a prescription. Yak heat-resistant zasib ibuprofen stagnates in that number and for new women. It has been reported that I lower the temperature more beautifully for the other non-steroidal anti-combustion devices.

In addition, ibuprofen is one of the most popular over-the-counter analgesics. Yak antiapalny zasіb wine is recognized not so often, protea drug to reach the popular in rheumatology: it can be used for treating rheumatoid arthritis, osteoarthritis and other sickness slopes.

Prior to the most popular trade names Ibuprofen were introduced by Ibuprom, Nurofen, MIG 200 and MIG 400.

naproxen

Naproksen zaboroneniy until stasuvannya children and adolescents younger than 16 years, and we will grow up, so we suffer from heart failure. Most often, the preparation of non-steroidal anti-pygmy naproxen is stagnant in painfulness in case of headache, toothache, periodical, angular and other types of pain.

In Russian pharmacies, naproxen is sold under the names Nalgezin, Naprobene, Pronaxen, Sanaproks and інshim.

ketoprofen

Ketoprofen preparations give rise to anti-firing activity. Wines are widely used for diseases and for lowering in case of rheumatic diseases. Ketoprofen is used for tablets, ointments, suppositories and injections. Before the number of popular drugs, the line Ketonal is introduced by the Slovak company Lek. Popularity to cure і nіmetsky gel for suglobіv Fastum.

indomethacin

One of the old non-steroidal anti-inflammatory drugs, endomethacin with a cutaneous day in the position. Winning Volodya with modest, sun-loving power and peaceful prototypical activity. In the rest of the rock, I will often call it "endometacin" to sound in obstetrics - it has improved its health to relax the muscles of the uterus.

ketorolac

Uniquely non-steroidal anti-fiery fires, but Volodya turns a sun-sickly soul. Analgesic properties of ketorolac due to the potency of weak narcotic analgesics. The negative side of the drug is that it is not safe: it is possible to avoid bleeding, provoke wiry ailment slunk, as well as pechinka lack. Tomato zastosovuvati ketorolac can be bridged for about an hour.

In pharmacies, ketorolac is sold under the names Ketanov, Ketalgin, Ketorol, Toradol and інshim.

diclofenac

Diclofenac is the most popular non-steroidal anti-inflammatory drug, the "gold standard" in the treatment of osteoarthritis, rheumatism and other lumpy pathologies. Volodya is seen as an anti-fiery and noble power, and that is widely stagnated in rheumatology itself.

Diclofenac can be used in vipusku-free forms: tablets, capsules, ointments, gels, suppositories, ampoules. In addition, the disintegration of the plaster with diclofenac will help you get rid of the trivial diy.

Analogues of diclofenac are even more bagato, and they are too overwhelming if they are not available from them:

• Voltaren is the original drug of the Swiss company Novartis. Become high yak and the same high price;
• Diklak is a line of useful medications in the company Hexal, which are both good and acceptable, and good quality;
• Dikloberl virobnitstva Nimechchini, Berlin Chem company;
• Naklofen - Slovak preparations from the KRKA company.

In addition, there are a lot of inexpensive non-steroidal antiapaline drugs with diclofenac in tablets, ointments and injections.

celecoxib

Suchasny non-steroidal ignition preparation, vibration blocking COX-2. Volodya has a high profile of safety and pro-firing activity. Stomach in case of rheumatoid arthritis and other diseases of the slopes.

Original celecoxib is sold under the name Celebrex (Pfizer company). In addition, in pharmacies, Dilax, Coxib and Celecoxib are more available.

meloxicam

Popular oil refinery, which is used in rheumatology. Come on herbal tract That one is often given a pass for the treatment of patients, who may have a history of discomfort or intestines.

I mean meloxicam in tablets, or in a few words. Meloxicam preparations Melbek, Melox, Meloflam, Movalis, Eksen-Sanovel and іnshі.

nimesulid

Most often it is necessary to become stagnant in the quality of a worldly, noble, and innocent - to a heat-resistant. More recently, a child's form was sold in pharmacies for a nimesulid, yaku was used for lowering the temperature, and it was categorically for children younger than 12 years old.

trade name nimesulidu: apon, Nise, Nimesil (original original drug in viglyadі powder for preparing a range for internal consumption) and іnshі.

On the other hand, a couple of rows of mefenamic acid are available. Even if it stagnates because of fever reducing, the protector signifies a step for the effectiveness of the other non-steroidal anti-inflammatory drugs.

Svit refinery is truly hostile to business development. It is unimportant on side effects, the goal is by right to be considered to the number of the most important and necessary, as it is not necessary to substitute, nor to bypass the side. Only to give praise to the unobtrusive pharmacists, who are promoting all the new formulas, and all the more non-baked refineries.

As it is, most people see pain in the back, connected with the problems of the ridge. There can be crosswise pains, or between the shoulder blades, which are not allowed to pierce, periodically or occasionally pierce. Nayposhirenіshoyu cause of cich pain є. More can be built up or grow rapt and ruin the way of life, encircling the rupture of the shoulder or the back in the area across. Obov'yazkovo zasosovanim zasob in such a situation in the old age from the list of non-steroidal anti-inflammatory drugs of the new generation.

Tse zhvoryuvannya ridge to produce up to step-by-step ruinuvannya. 3 o'clock mid-spine discs I siphon off the power of my function in the world, play the role of shock-absorbing pads between ridges, stench on the vologue, they have tremors, springiness of them. At the connection with the cym, it changes into ridges, and the nerves of the roots, which go out spinal cord, To shrink, and to ignite on the basis of the fabrics. On the whole background there can be developed іnshі zhvoryuvannya ridge. Tse can be buty, mіzhhrebetnі gryzhі and іnshі.

Our organisms have such special speeches, the role of which is accumulated in the firing place, to give a signal about the detection of a problem in the singing hallway. The axis of our organism and signaling is due to the pain syndrome. The ridge needs additional help!

Plusi new generation refinery

In the rest of the era, it is widely used in medical education for the new generation. Qia group is so called selective drugs in the oil refinery.

We are even more important їх experience є those who smell more vibrantly injected on the body, so that those who need to be liked, and the least amount of work to be applied to healthy organs.

So the side effects on the side of the intestinal tract, the loss of the larynx of the blood, is less important, and the tolerance of these drugs is increased. In addition, the new generation of NPZP drugs can be actively victorious in the case of sickness of sugars, sprinkles, and arthritis, since the stench on the mind of nonselective NPPPs does not intimidate the negative infusion on the clitine lump cartilage, And it means є chondroneutral.

List of non-steroidal anti-inflammatory drugs of the new generation

A list of popular and effective non-steroidal anti-pyretic drugs:

It is important for the nobility at the refinery

All the people of the new generation got a wider expansion. In case of osteochondrosis of the refinery, the drugs are recognized:

1. at viglyadі ін'єкцій (pricks);
2. for oral administration - in tablets, capsules;
3. for rectal zasosuvannya - in the form of sv_chok;
4. for the call of the viglyad gels ,.

The stench can be counter-indicative in case of an individual intolerance. We are sick of the kidnapped vіku after taking special care, and during the period of lіkuvannya necessary retail control over the camp of the liver and nirok patients.

It is not recommended to pick up a refinery for dealing with ailments, in the course of which it is necessary to improve the respect, accuracy, quick response and coordination of ruins, for that, because of the possibility of drowsiness, weakness, headaches.

It is necessary for the nobility, who only non-steroidal anti-fatigue in case of elimination of osteochondrosis, arthritis, and those with illnesses, it is not a matter of getting sick again, since the reasons are meant for the loss of knowledge. For a further treatment, the necessary preparations and therapy methods are required.

It is important to remember that a trivial stagnation can lead to the appearance of irrelevant side effects at the refinery, which is unacceptable without a permanent control of the drug.