Ketoacidotic coma of ICD 10. Diabetic ketoacidosis - description, causes, symptoms (signs), diagnostics, treatment

diabetic ketoacidosis- tse is not safe for a life of accelerated life, but a person with ailments has a diabetic.

The process of acceleration is characterized by the non-stagnation of the special hormone insulin (it is caused by the drop in glucose in the blood of people), so the level of acidity to the body itself is improved; moss of acetone in the patient's section.

Danish ailments reach the broadening of the middle of diabetics, especially of those suffering from tuberculosis. When a disease of type 1 occurs, it can serve as the first symptom of a disease, most often it develops through an unfortunate diagnosis of ailment. Proceedings are accelerated most often, right up to ketoacidotics.

Ketoacidosis can develop as a result of injuries, for example, prompt engagement... For people with diabetics of another type, the development of accelerated development is meaningful, winery as a result of early infectious diseases sectional system, Infarction and Insult.

Provokuvati this can and the disease of the endocrine system, such as thyrotoxicosis. Against ailment, you should not be so intense, as with the first type, so as you will be invariably present.

Let's get rid of ketoacidosis and the signs of acceleration.


The reasons for the acceleration

The reasons for the diagnosis of keotacidosis are not so abundant. Most often, it is the cause of the disease є it is unfortunate to diagnose(In case of type 1 diabetes), so the very reasons can be Infectious diseases, Rіznі injuries, problems with the cardiovascular system (myocardial infarction).

Another reason for the occurrence of ailments may be that the dosage of insulin-containing preparations has been incorrectly taken.


Stages of development

1 stage
Dana stadiya characterized by mild symptoms of spraggy symptoms, frequent going to the toilet, headaches... Even people with diagnosed infants with diabetes would like to see symptoms, even if they suspect unkindness.

2 stages
The stage of development is called prominence. The pathogenesis of early descriptions of symptoms characteristic of the strongest. They get bloated, tachycardia appears (the rhythm of the heart is very quick to grow), the speed of reactions decreases, the time to fix it is better to react to the bright light, maybe it’s stagnant, it’s dry. The smell of acetone, if it didn’t come to the end, would appear in the company, if the smell would be present, then it would be accepted and we would become more remembered.

3 stages
Naivazhcha stage with success. It is characterized by the second testimony, by the general reaction to the calls of the party (the light is not a waste of time, as they spend the whole hour in a ringing camp). The smell of acetone is so strong that you can see it in a decent place, you can see it in a strong and dignified manner (the so-called “Kussmaul's dichanna”). On this stage, the stage of ailment falls into a Ketoacidotic coma.


diagnosis of ketoacidosis

In laboratory minds, the process of accelerating diagnostics is carried out by way of analysis for ketones and acetone. So it’s very easy to analyze blood instead of calories, glucose and ketones. A test can be carried out independently; in the pharmacy it is possible to buy a special test-smuzhki for conversion in place of acetone in the section.

Important!

The result is excellent - it is necessary to turn to the doctor!

Likuvannya and unavailable help

at state-of-the-art development an important stage of ailment, it is necessary to make a number of visits to get a normal life before the arrival of doctors and the cob of therapy in reanimation.

In case of a zupinka, it is necessary to preserve the surge of energy to the legends, for it is necessary to carry out the ventilation by means of a piece of work.

Bazhano monitor indicators of the ailing before the arrival of a shvidkoy help, schob poviditi fakhivtsyam ostannі danі.

It is necessary for the renewal of great societies in the country, in the second hour of ailment, for insulinotherapy to be carried out, even when the dose of acetone is transformed into the patient's section and the blood in the blood of ketones. A weakening of the pathological camp of a sick person is carried out, and his indicators are monitored.

Ketoacidosis in children

The most frequent signs of accelerated manifestation are raptus and hospitality.

It is tied to the earlier non-emerging type 1 diabetes. Symptoms of illness in children are identical to those in older adults, only when organisms have not been formulated before the end of the ketoacidosis, to accelerate to development.

The reasons may be that the dosage of insulin-containing drugs is incorrect or irregularly administered, stressful situations so it can be naughty kids. If you are sick with an ailment, it is necessary to carry out a test for acetone instead of in the section, and you can more quickly show the child of fakhivtsev.

preventive maintenance

If you already have a diagnosis of "diabetic diabetic", then you need to take care of the development of the disease. drugs in the home minds.

When accepting a decision about thinning, it is necessary to keep it safe, Do not skip losing the keys too quickly, it is necessary to step by step reduce the amount of money to the bazhany rivnya. For ailments with the first type of diabetes, there are no strict obmezheni in їzhі, it is enough viconuvati to please the lykar who dozuvannya insulinu.

For ailments of a different type, it is necessary to catch up with a suvorian child for the unification of repeated relapses.

Corisne video

From this video, can you know how to get a great amount of acetone in your body?

Ketoacidosis is an even more insecure and tricky enemy that must be fought for. For the international classification of ailment (code for MKH 10) ketoacidosis is assigned a code - E10-E14.

In case of symptoms of illness in oneself or someone from close ones, it is necessary to carry out all the necessary manipulations and turn up to the doctor.

Baby ketoacidosis- a heterogeneous group of stanіv, which is supervised by the appearance of ketone bodies in the blood and in the blood. Ketones are the carriers of energy from the liver to the other tissues, and mainly the energy that is captured by the brain tissue from the liver. Main reasons ketoacidosis in newborns - diabetes mellitus, type I glycogenosis (232200), glacinemia (232000, 232050), methylmalonic aciduria (251000), lactic acidosis, lack of succinyl - CoA - acetoacetate transferase.

Code for the international classification MKH-10 ailment:

  • E88. eight - Інші clarification of the damaged exchange of rechovins

Lack of succinyl - CoA - acetoacetate transferase (# 245050, EC 2. 8. 3.5, 5p13, SCOT gene defect, r) - the mitochondrial matrix enzyme, which catalyzes the first steps in the drop of ketone bodies.

classically

important recurrent ketoacidosis, blues, backwardness.

laboratory

lack of succinyl - CoA - 3 - acetoacetate transferase, ketonuria.

Richards-Randle syndrome (* 245100, r) - ketoaciduria with rosum deficiency and other symptoms.

classically

rozumova vіdstalіst, ataxіya, weak development of secondary state signs, deafness, atrophy of peripheral musculature.

laboratory

ketoatsiduria. synonyms: syndrome of ataxia - deafness - retardation of development with ketoaciduria.

Lactic acidosis is a splinter of types that are affected by mutations in lactic acid metabolism enzymes: lack of LIPO transacetylase E2 (245348, r, À); ... lack of a component of the pyruvate dehydrogenase complex to avenge X - LIPO (* 245349, 11p13, PDX1 gene, r); ... congenital infantile form of lactic acidosis (* 245400, r); ... lactic acidosis with type D - lactic acid (245450, r). Signs of the head - lactic acidosis, occlusion of psychomotor development, hypotonia myazova. Deyakі form mayut specific manifest, such as microcephaly, muscular mucus, oblivion, necrotizing encephalopathy and іn.

Ketoadipin aciduria (245130, r).

classically

the pathology of the shkiri (collodion shkira), the bulging of the hands and feet, covering the development, myazova hypotonia.

laboratory

hyperexcrescence from section a - ketoadipinic acid.

ICD-10. E88. 8 Інші clarifications damaged exchange of speeches.


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Make a comment before: Ketoacidosis in children(Sickness, describe, symptoms, folk recipesі lіkuvannya)

14.1 ICD-9 250.1 250.1 DiseasesDB 29670 eMedicine med / 102 med / 102

diabetic ketoacidosis (ketosis, ketoacidosis) - a variant of metabolic acidosis, dressings with impaired carbohydrate metabolism, in case of fatty acid deficiency: a high concentration of glucose and ketone levels in the blood (meaningfully changing the impairment of carbohydrate metabolism), the result If the loss of carbohydrate metabolism is stopped quickly - a diabetic ketoacidotic coma develops.

non-diabetic ketoacidosis (acetone syndrome in children, cyclical acetone bleeding syndrome, acetonemic bloom) - the prevalence of symptoms associated with the increase in the concentration of ketone cells in the blood plasma - a pathological state, which is important to develop in childish It appears to be stereotypical repetitive episodes of blues, and to be guarded by periods of general well-being. To develop as a result of failures in children (trivial hungry pauses or overwhelming living in fat), as well as on somatic, infectious, endocrine diseaseі lesion of the central nervous system. Primary (idiopathic) development - occurs in 4 ... 6% of children from 1 to 12 ... 13 years and secondary (on the background of illness) acetone syndrome.

In the norm in the body of people, as a result of the main exchange, they gradually establish and utilize the tissues (muffins, nirks) of ketones:

  • acetoacetic acid (acetoacetate);
  • beta-hydroxybutyric acid (β-hydroxybutyrate);
  • acetone (propanone).

As a result, there is a dynamic concentration in blood plasma in the normal range.

wideness

Diabetic ketoacidosis occurs after the first time in the middle of the gostrich, the endocrine ailments are accelerated, the mortality rate reaches 6 ... 10%. Children with insulin-dependent winter diabetics have the most common cause of death. All types of this country can be divided into two groups:

  • diabetic ketosis - a condition that is characterized by an increase in ketone levels in the blood and tissues without a severe toxic effect and dehydration;
  • diabetic ketoacidosis - in vipads, if there is not enough insulin to compensate for exogenous injections, or if you do not suspect the cause, it is susceptible to induced lipolysis and ketogenesis, the pathological process is progressing towards the growth of water supply

In such a rank, the pathophysiological changes in their stan- dards are brought up to the stage of metabolic disturbance.

Ethiology

best often the reason development of overgrown ketoacidosis є type 1 diabetes. Diabetic ketoacidosis of vinikє through an absolute abnormal deficiency in insulin, which develops in a stretch for years or days.

I. In ailments, we will first appear on the insulin-free fallowing diabet, a partial abnormal deficiency of endogenous insulin viklicanii zagibella beta-clitin of pancreatic ailments. II. In ailments, who recognize the insulin, the causes of ketoacidosis can be: 1. inadequate therapy (a sign of low doses of insulin); 2. violation of the insulin therapy regimen (skipping the insulin, stitching the drug insulin); 3. rіzke pіdvischennya Consume in іnsulіnі in ailments with іnsulіnаlіznimnuyuchrovym diabetics: a) Infectious diseases: sepsis (abo urosepsis); pneumonia; іnshі іnfections of the upper dyshols sečovyh nobles; meningit; sinuiti; periodontitis; cholecystitis, pancreatitis; paraproctitis. b) supportive endocrine disruption: thyrotoxicosis, Cushing's syndrome, acromegaly, pheochromocytoma; c) myocardial infarction, stroke; d) injuries і / abo surgical involvement; e) drug therapy: Glucocorticoids, estrogens (including hormonal contraceptives); f) vagіtnіst; g) stress, especially in the middle period. In all food and drink, the increase in consumption in insulin is backed up by the increased secretion of counterinsular hormones - adrenaline (norepinephrine), cortisol, glucagon, STH, as well as insulin resistance - III. In four ailments, the reason for the development of diabetic ketoacidosis is not to be found.

pathogenesis

In the minds of the unstable energy, the organism of the people is the vikorist glycogen and the reserves of the lipid. The reserves of glucogen in the organism are albeit relatively small - close to 500 ... 700 g, as a result of this splitting glucose is synthesized. Slid means that the brain, being behind the bud's lipid structure, will reject energy in the main utilization of glucose, and acetone for the brain - toxic speech. In connection with the tsієyu especialty, without the mediocre splitting of fat, it is impossible to preserve the energy of the brain. So, since the reserves of glucogen are altogether small and hang out for a stretch of decile days, the organism can prevent the brain from being energized, either for additional gluconeogenesis (endogenous synthesis of glucose), or an alternative to increasing blood circulation in the concentration of energy In the norm with a deficiency in carbohydrate, the liver with acetyl-CoA synthesizes ketone thyl - ketosis, but not wiklik electric piston(Є version of the norms). However, in a number of vipads, there is also a possibility of decompensation and development of acidosis (acetone syndrome).

lack of insulin

1. Deficiency of insulin is produced to hyperglycemia with osmotic duresis, dehydration develops and electroplasma is destroyed. 2. Addition of glucose viroblast - it is possible to adapt to glucogenolysis (decrease of glucogen to glucose) and gluconeogenesis (synthesis of glucose from amino acids, which is established in case of loss of blood). In addition, lipolysis is activated, which leads to an increase in the level of essential fatty acids and glucerin, as well as the production of glucose. 3.Additional additions to the adjustment of glucose level in blood plasma to make:
  • a decrease in the utilization of glucose by tissues, as a result of not only the deficiency of insulin, but through insulin resistance;
  • Change of obsyagu pozaklitinnoi rіdini (inheritance of osmodiuresis), to reduce the level of blood flow і to the absorption of glucose into the organіzmі.
4. In response to a decrease in the energetic disease of organs and tissues (glucose without insulin cannot penetrate into cells), the furnace repairs the synthesis of ketone thyl (ketogenesis) - ketonemia develops, which progresses through the disease. There is a smell of "acetone" in every drink, when you see it. An increase in the concentration of ketone particles in the blood will give a nirkovy porigus, which can lead to ketonuria, and it will be superbly supervised with more efficient recovery of electrolytes (cations). 5. Deficiency underwent: the production of ketone cells is uncontrolled and the supply of the pool is uncontrolled;

The role of counterinsuline hormones

clinika

Ketoacidosis is a legacy of severely decompensated sugar diabetes and develops with an important, labile transition to aphids:

  • admission of inter-competitive ailments,
  • injuries and surgical involvement,
  • wrong and unfortunate correction of dozi insulinu,
  • unfortunate diagnostics of the forthcoming red diabetes.

A clear picture is characterized by symptoms of rotational decompensation of illness:

Diabetic ketoacidosis is not an adolescent state, but a patient's hospitalization. In case of an unfortunate and inadequate therapy, a diabetic ketoacidotic coma develops.

diagnostics

Ketone salts є acids, і liquidity іх assimilation and synthesis can be derived; There can be a certain situation, if, through the high concentration of keto acids in the blood, acidic acid changes develop, metabolic acidosis develops. During the development of ketosis and ketoacidosis, during ketosis there are no changes in the blood, and the stage of physiological status. Ketoacidosis is a pathological condition, laboratory criteria for a decrease in blood pH lower than 7.35 and a standard blood bicarbonate concentration of less than 21 mmol / l.

lykuvannya

ketosis

It is a practical tactic to be developed to the point of asserting the reasons, which provoked ketosis, intercourse in the races of fat, signs of puddle pitt (puddles of mineral water, razchini soda, regidron). It is recommended to take methionin, esential, enterosorbents, enterodez (5 g in 100 ml of boiled water, boiled for 1-2 times). Even though such ketosis is not known, it should be noted that a short period of time (for the recommendation of the doctor!). As a patient, you have already taken an insulin in one іn'єktsії on dobu, to completely switch to the mode of Intensification Insulinotherapy. Recommend cocarboxylase (internal), splenin (internal) course 7 ... 10 days. to docilely signify the pools of cleansing klizmi. Even though ketosis does not suspect any special inconsistencies in the hospitalization, it’s not necessary to go into the home minds if possible.

ketoacidosis

With severe ketosis and progressive decompensation of diabetic diabetes, the patient needs a stationary treatment. The order with re-insured visits should be done to correct the dose as soon as possible, go to the introduction of only a short period of time (4 ... 6). to carry out internal infusion of sodium chloride (physiological breakdown) from the patient's patient.

Patients with important forms of diabetic ketoacidosis, stages of adherence to the principle of diabetic Komi.

forecast

With a free-spirited correction of biochemists, he is friendly. In case of an unfortunate and inadequate therapy, ketoacidosis through a short stage of precoma passes into a diabetic coma.

prophylaxis

  • Seriously staged to my own camp, taking into account licars' recommendations.
  • Technique for the preparation of the insulin, the correct preparation of the preparation in the insulin, the correct dosage of the preparation, the retransfer of the preparation in the NPH-insulin or the preparation ex tempore of the sum of the short and NPH-insulin before. Vidmov from the test of stitched preparations in insulin (besides, the previous victories of allergic reactions!).
  • Nowadays, the brutality behind the medical aid in times of the ineffectiveness of the self-directed attempts to normalize the camp.

Div. also

  • Hyperosmolar coma

Notes

posilannya

  • Ketosis і ketoacidosis. Pathobiochimic and clinical aspect. V.S.Lukyanchikov

categories:

  • Zagvoryuvannya for the alphabet
  • endocrinology
  • diabetology
  • Diabetes mellitus
  • urgent
  • insulinotherapy
  • metabolic disease

Wikimedia Foundation. 2010 rock.

Acetonemia syndrome is a complex of symptoms, which is caused by the failure of the exchange of words in the body. The result is the accumulation of ketone til. Tse pathological stan, which is supervised to move in the blood of acetone, acetoacetic acid.

Zestrіuvannya grow up in a childish vіtsі. Appear as stereotypical and regularly repeated episodes, which are cherished from periods of general prosperity.

The primary form is observed in 4-6% of children from all to rock up to 13 years. They are as smart as a little girl. The average rate of blues manifestation becomes 5.2. Half of all patients will require relief of the symptom complex by means of an intravenous method.

The second form develops when it is obvious fellow sickness and for operations. For her, a clear provocative factor is required.

Code for MKH-10

For ICD-10, the syndrome is not seen in the quality of the nosological unit. Ale in pediatric patients are often aware of the abnormalities of the metabolic processes, which are supervised by the described pathological camp.

For the classification it is taken to acetone (code R82.4). At the same time, there will be changes instead of acetone in the section.

cause development

The main reason is the absolute lack of carbohydrates in the diet or the overloading of fatty and ketogenic acids.

Changing the mind for the acetone syndrome є, as the guilty brothers take an active part in oxidative processes.

If there is a lack of carbohydrates in the body of the wine, energy consumption will be compensated for by lipolysis. Tse to produce to form a large amount of fatty acids.

There is a great number of ketone salts to produce to the breaking point in the acidic sphere and water-electrolyte. Tse nadaє toxic diyu on nervous system, Shlunkovo-intestinal tract. Provocative factors may include vistupati:

  • stress;
  • GRVI;
  • pneumonia;
  • neuroinfections.

One of the reasons for hunger or overwhelming. With the infusion of decilex unpleasant factors, ketosis is formed.

With a significant adjustment of the ketoacids of vinikє metabolic acidosis... The surplus of ketone til nadaє on a strong inflow to the central nervous system, which leads to the development of a comatose stun.

Symptoms of acetone syndrome in children

Having shown a classic attack, you can get it to the bottom. Get started with assaults. The frequency and the triviality of staying in the cob ryvnya of health and the time of the child.

In some cases, they are lonely, but sometimes they are repetitive. Її wiklikє and try to drink some water. Signs of intoxication are formed through the price.

Ditina blidne, ale on her cheeks there is a bright, unhealthy blush. There is a step-by-step decrease in the activity of the child, tied to the meat weakness. Malukovy old, grab your hands, get up from the couch.

The attack is characterized by the stage of neurological and key manifestations... At small doses of acetone, vinikє zbujennya. Malyuk started shouting, making posters, showing up in peace.

The world of accumulation of toxic products is awakened by sleepiness, without silliness. In case of severe progressing ailments, you can attack by court, waste of evidence.

Video about acetone syndrome in children of the school of Dr. Komarovsky:

diagnostics

Zazvychay daddy wiklikayut I will help the shvidka through uninterrupted blues. In the minds of the stationary, an analysis of slaughter and blood is taken. Appear, but a bit of acetone in the biological ridges of the arch.

Nadal in the home minds can be victorious test-smugs, so they allow you to start using acetone in the section for the preparation of drinking and prophylactic visits.

Chim yaskravish kolіr smuzhlya pislya zanurennya in the cut, tim vische rіven ketone bodies. The methodology is more than outrageous, it only allows for an approximate assessment of the steps of gravity.

In drugs, the amount of acetone is measured in units of abo mol / l. When decrypting the form, there is a plus. In case of one abo, two tests are carried out in the home minds. If the plus is 3-4, then there will be a liking in the drug, some of the winners of the life-threatening camp.

lykuvannya

Likuvannya is carried out in 3 stages:

  • First. At the cob stages, or when there are moles, the intestines are cleaned with 1-2% solution of sodium bicarbonate. Ditin slid to sing skin 10 chilin, liquorice tea or compote. Hunger is not necessary, ale diet becomes the main method of drinking. If necessary, antispasmodics are indicated. For vivedennya ketones vikorystovyutsya enterosobrenti.
  • Another. If there is a bagatoraz bloom, the intestines are cleansed and carried out infusion therapy... For the rest vikoristovuuє As a child, parenteral administration can be substituted for oral hydration. In case of unstrimming bloating, consider Metoclopramide and antispasmodics. In case of overwhelming anxiety, tranquilizers are to be typed.
  • Third. Conjugation for the normalization of the exchange of words and prevention of recurrences. For tsiy it is necessary to take a child. Dotrimuvatisya її all life will be brought.

cerucal

Tse of widening, stagnation in acetone syndrome. Vin is a blocker of dopamine receptors, in the form of anti-malarial lesions. Vypuskayatsya in ampoules for ін'єкцій.

dyeta

In case of a crisis, it is necessary to drink liquorice tea, ist kavuni chi dini. Mozhlivo implantation of mineral water. Remaining can not be victorious in the fallacy, as part of the diet and acetone.

At the stage of the transfer (, blah, head bill, The smell of acetone from the mouth) the child is not guilty of starving. If the blues appear, then nagoduvat the child will not see.

Give a varto product, which can be easily consumed in carbohydrates. Tse can buty bananas, vegetable puree, kefir, rydka manna porridge. In the smallest quantities it is possible to eat Greek, vevsyan, corn porridge, baked apples of licorice varieties, biscuit biscuits.

When polіpshennі zagalny stan, ovine soup is introduced. I will get a chance to taste pickles, smoked meats. All products are steamed or cooked. Give a child a skin for 2-3 years.

The main principle of food is the inclusion of products from the ratio of purines and fats in great quantities. The emphasis is on the production of dairy products, vegetables and fruits during the period of remission.

Forecast and prevention

Children with a syndrome of guilt have been transferred to the endocrinologist's office; The forecast is generally friendly.

In the world, the growth of the acetone crisis will rise. Most often it takes place in the middle of the day. When you immediately dismiss medical aid and with competent management tactics, ketoacidosis can be eliminated.

When diagnosing recurrent acetone stagnation, it is necessary to take a high-carbohydrate and high-carbohydrate diet, and regularly reconsider the presence of acetone in the test for a test. It is important to uniquely trivial interruption between the priyoms of the їzhі.

Diabetes mellitus is not uncomfortable with its accelerated disease, one of which is ketoacidosis.

Tse gostre іnsulenodefіtsіtnoe stan, zdatne, when every day comes to medical correction, lead to a lethal result.

Also, these are the symptoms that are characteristic for a person who will become and will not allow the best result.

Diabetic ketoacidosis: what?

Diabetic ketoacidosis is a pathological state, associated with improper carbohydrate metabolism through insulin deficiency, as a result of which a small amount of glucose and acetone in the blood often changes normal physiological indicators.

Name Yogo... It is necessary to be referred to the category of stanіv, so as to clutter up the life.

If the situation with the loss of carbohydrates is not immediately stopped by medical methods, a ketoacidotic coma develops.

The development of ketoacidosis can be noted by characteristic symptoms, About yakі mova pіde trohi pіznіshe.

clinical diagnostics I will be based on biochemical analyzes of blood and slaughter, and based on:

  • compensatory insulin therapy;
  • rehydration (rehydration);
  • updated electrical exchange.

Code for MKH-10

Classification of ketoacidosis in case of sugar diabetes occurs as a type of main pathology, to the code value which can be reached ".1":
  • E10.1 - ketoacidosis in case of insulin-free fallow sugar diabetes;
  • E11.1 - in case of non-insulin dependent diabetes mellitus;
  • E12.1 - in case of diabetic diabetic caused by lack of food;
  • E13.1 - in case of other specified forms of diabetic diabetes;
  • E14.1 - with unspecified forms of sugar diabetes.

Ketoacidosis in diabetes mellitus

Diagnosis of ketoacidosis with different types Diabetes has its own specialties.

1 type

call it, juvenile.

Wine is an autoimmune pathology, when a person is constantly in need of insulin, that is why his organism is not viral.

Damage to be of an incongruous character.

The reason for the development of ketoacidosis in the whole range is called an absolute lack of insulin. If the type 1 diabetes is not readily diagnosed, then the ketoacidotic state can be a manifestation of the main pathology in quiet people, who did not know about their diagnosis, but that means they did not reject the therapy.

Type 2

- tse nabut pathology, when such insulin is synthesized by organism.

on cob stage This number can be normal.

The problem is in a decrease in the sensitivity of tissues to the level of blood hormone (which is called insulin resistance) through the destructive changes of beta-cytoplasm.

The winery is an obvious lack of insulin. Over the course of the year, in the world the development of pathology, the development of a strong insulin fall, and in some cases it will be blocked more and more. There is no reason for the development of ketoacidosis, as people will not reject adequate medication.

Finding and indirect reasons, creating a provocative state of affairs, viclikaniy gostriy marriage insulinu:

  • the period of the transfer of pathologies, infectious etiology, and injuries;
  • pislyaoperats_yny camp, especially, when surgical involvement stosuvalosya pidshlunkovoy zalozi;
  • storing medications that are not suitable for diabetes mellitus (for example, hormones and diuretics);
  • and further away from the chest.

step

In terms of severity, ketoacidosis will increase by 3 steps, the skin will develop in its manifestations.

Easy foot characteristic of tim, scho:

  • Lyudin suffers from frequent poses until the next day. Zayva vtrata rіdini suprovodzhutsya postynoy zhagoyu;
  • "Spinning" and a headache, feeling drowsy;
  • appetite is reduced on tlі tediousness;
  • travel more in the epigastric day;
  • fortunately, you see the smell of acetone.

Middle Steps to turn to destruction I will begin to manifest myself, but:

  • evidence to wander, to cope with reactions;
  • tendon reflexes are reduced, and the magnitude of the decrease does not change due to the flow of light;
  • sposter tachycardia on the low arterial vise;
  • from the side of the shlunkovo-intestinal tract, a bloom and a thin style are added;
  • the frequency of the sechovipusk is speeding up.

important steps are characterized by:

  • falling into a non-sacred camp;
  • attributed to reflex responses to the body;
  • Sounds of light when there is an increase in the visibility of the reaction to light;
  • let's remember the presence of acetone in every day, how to see, navigate to the days of the people;
  • hot water (dry nesting curves and mucous membranes);
  • gliboky, childish and noisy dinosaurs;
  • to the liver, it is pleasant to the palpation;
  • zrostannyam rivnya zukru in blood up to 20-30 mmol / l;
  • high concentration of ketones in blood and blood.

cause development

The most common cause of ketoacidosis is type 1 diabetes.

Diabetic ketoacidosis, as it has grown earlier, winy through a deficiency (absolute abnormal) insulinu.

Win buvak of summations:

  1. Zagibella pancreatic beta-clinin.
  2. Neurological therapy (lack of quantity of the introduced insulin).
  3. Irregular intake of insulin preparations.
  4. a sharp strik Consume in insulin when:
  • infectious diseases (sepsis, pneumonia, meningitis, pancreatitis and others);
  • problems with the robot organs of the endocrine system;
  • strokes and infarctions;
  • in the face of stressful situations.

In all these cases, the need has grown for insulin-induced hormone secretion, which will increase its functionality, as well as the lack of sensitive tissue until the next day.

In 25% of diabetics, the cause of ketoacidosis is not given out.

symptoms

In detail about the symptoms of ketoacidosis, the viscera has fallen asleep, if it is about the stages of the severity. Symptoms of the cob period with an hour of build-up. Little by little, there are signs of a deterioration and progressive gravity.

As soon as there is a possibility of "talking" symptoms in ketoacidosis, then it will not be:

  • polyuria (often sechovipuskannya);
  • polydipsia (postyna spraga);
  • eksіkoz (vnevodnenya organіzm) і wines due to the dryness of the shkіri and mucous;
  • , since glucose is not available;
  • dikhannya Kussmaul - one of the forms of hyperventilation in diabetic ketoacidosis;
  • clearly "acetone" presence in the twilight, how to be seen;
  • destruction of robotic organs shlunkovo-intestinal tract Supravodzhuyutsya tediousness and bloating, as well as pain in the abdomen;
  • I’ll be shyly progresuyuche pogirshennya, right up to the development of ketoatsidoticheskoykomi.

Diagnostics and treatment

Frequently, the diagnosis of ketoacidosis is complicated by the similarity of the symptoms with the other masses.

So, the manifestation of boredom, bloating and pain syndrome in an epigastrium is taken for signs of peritonitis, and a person is consumed in a surgical procedure instead of an endocrinological one.

Schob viyaviti ketoacidosis of diabetes mellitus, required come in:

  • consultation of a doctor-endocrinologist (aka diabetology);
  • biochemical analyzes of blood and blood, including for the level of glucose and ketone salts;
  • electrocardiogram (schob viklyuchiti myocardial infarction);
  • roentgenography (for reconciliation on the subject of secondary infectious pathologies of the organs of the community).

Likuvannya is a sign of licor, primed on the results of the survey and clinical diagnostics.

With a whole lot of such parameters, such parameters, such as:

  1. I will become heavy;
  2. Steps of turn of decompensatory signs.

Therapy is stored from:

  • internal introduction of insulin-containing preparations, for normalization of glucose levels in the blood, with continuous control of the camp;
  • degraded visits, directing to the memory of the overworldly vivedenoi age. Name the dots with physiological differences, or, for prevention, the development of hypoglycemic indications of glucose levels;
  • logging in on the basis of the normal interruption of electrical processes;
  • antibacterial therapy. Vona is necessary for a person infectious diseases;
  • anticoagulant intake (medications that reduce the activity of the throat), for the prevention of thrombosis.

All households come in to be seen in the minds of the stationary, with references in the reanimation of the announcement. To that, the view of the hospital can be a great life.

accelerating

The period of development of ketoacidosis can be from decilcoh years to decіlcoh days, some more. As you do not live in, there are a number of accelerated victories, in the middle:

  1. Metabolic rosters, for example, are tied to the "vimivans" of such important microelements, such as calcium and calcium.
  2. Non-metabolic products. Including:
  • strong development of other infectious pathologies;
  • viniknennya shock stanіv;
  • arterial thrombosis as a result of dehydration;
  • a load of legends and a brain;
  • coma.

Diabetic ketoacidotic coma

If you have a problem with carbohydrate metabolism, if you suffer from ketoacidosis, you will not get sick quickly, it will develop faster, it is not safe for life - a ketoacidotic coma.

Vona grows up in some cases of age, with a total mortality rate in people under 60 years of age becomes up to 15%, and in older diabetics - 20%.

The viclikati development of the Komi can be furnished as follows:

  • a small dose of insulin;
  • skipping insulinovaya in''ktsii for taking sucrose tablets;
  • Therapy, which normalizes the amount of glucose in the blood, without the use of a drug;
  • the technique of introducing the insulin preparation is incorrect;
  • the presence of specific pathologies and other factors that are injected into the development gratefully accelerated;
  • implantation of unauthorized doses of alcohol;
  • self-control will become healthy;
  • taking okremikh medications.

The symptomatology of ketoacidotic coma is abundant in what to lie in the form of:

  • in case of abdominal form, the symptoms of "grave peritonitis", tying robots and organs of etching, are often tied;
  • with heart-vascular head signs є dysfunction of the heart and sudin (hypotonia, tachycardia, pain in the heart);
  • with nirkovy form - abnormally cherguvannya frequent sechovipuskan from the periods of anuria (the duration of the positive before the date of the meeting);
  • with encephalopathic - there are changes in blood circulation impairment, which manifests itself as headaches and impairment, loss of health and supine boring.

Ketoacidotic coma is an important stump. Unimportant on the price, it is possible for a friendly prognosis to reach the top, as long as there is a lack of medical assistance in less than 6 years since the first signs of acceleration have appeared.

On the other hand, ketoacidotic coma with infarction, or problems of blood circulation in the brain, like every hour of the day, it’s a pity, it’s fatal.

I’ll get to know the risk of getting rid of it, about what kind of news is in the tsiy statty, you need to follow up on the prophylaxis:

  • take a dose of insulin in a timely manner and correctly, as indicated by a drug;
  • badly dotrimuvatisya established rules of eating;
  • Immediately controllable sv_y stan and immediately develop symptoms of the development of decompensatory manifestations.

Regularly reviewing the doctor's recommendations, as well as respecting his health, to allow the removal of such important and unfinished countries, Yak ketoacidosis and acceleration.

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