Shlunkovy sik: what to store and most of the time it is needed. The main components should enter before the shlunk juice storage for the people.

slunkє bag-shaped extension herbal tract... Yogo projection on the front surface of the cranial wall is shown as an epigastric day and partly to liva pidreber'ya... In the slunker, there are such views: the upper - the bottom, the great central - tilo, the lower distal - the antral viddil. The misplaced shlunka with the strainer is called cardial viddil. The pyloric sphincter is seen instead of the slunk from the two-fingered intestine (Fig. 1).

  • depositing їzhі;
  • mechanical and chemical processing;
  • the act of evacuation of the grub vimistu in the gut.

Fallow chemistry warehouse and only a few of those accepted are in the slurry from 3 to 10 years. With a lot of grubs, the masses are refined, mixed with slunk juice and grown. Living speech are fed with enzymes in shlunk juice.

Warehouse and power plant for slurry juice

Shlunkovy sіk viroblyasya secretory vines of the mucous membrane of the shlunkovy. In addition, purge 2 - 2.5 liters of shlunk juice. There are two types of secretory nesting at the slimy shlunk.

Small. 1. Pidrozdіl of the slunk on the wedge

In the area of ​​the bottom and bottom of the slurry, the acid-producing zone is localized, which occupy approximately 80% of the surface of the slime shell of the slurry. The stench is the perishing of the mucus (cinder pits), which are set up with three types of cells: head cells produce proteolytic enzyme pepsinogen, cladding (steam rooms) - hydrochloric acid i dodatkovі (mukoїдні) - mucus and bicarbonate. In the area of ​​antral viddil, zolozovyutsya, as vyroblyayut mucus secret.

A clean shlunkovy sіk is a barless insight into a rіdinu. One of the components in slurry juice is hydrochloric acid, which pH become 1.5 - 1.8. The concentration of hydrochloric acid in the slurry juice is 0.3 - 0.5%, pH Instead of the slunker, it may be worthwhile to receive it. pH pure slurry juice as a result of dilution and neutralization with puddle components. Before the storage of slurry juice enter non-organic (they are Na +, K +, Ca 2+, СI -, НСО - 3) and organic speech (mucus, dyes, metabolic products, enzymes). Enzymes are established as head clays of shlunkovye zoloz in an inactive form - at the viglyad pepsinogens, which are activated when small peptides are added from them, when hydrochloric acid is injected and transforms into pepsin.

Small. The main components of the slurry secret

Pepsin A, gastrixin, parapepsin (pepsin B) are taken up to the main proteolytic enzymes in slunk juice.

pepsin A I will split the protein to oligopeptides when pH 1,5- 2,0.

Optimal pH for the enzyme gastric become 3.2-3.5. Vvazhayut, pepsin A and gastrixin dyut on the basis of the type of protein, without providing 95% of the proteolytic activity of slunk juice.

Gastrixin (pepsin C) - proteolytic enzyme to the secretion of the slunk, which is the maximum activity at a pH of 3.0-3.2. In active pepsin it hydrolyzes hemoglobin and does not enter pepsin in the liquid hydrolysis of egg white. Pepsin and gastrixin provide 95% of the proteolytic activity of slunk juice. Yoogo part in the slunk secretion becomes 20-50% of the amount of pepsin.

pepsin B in the process of slurry pickling and splitting into the main gelatin. The status of enzymes in the slunk juice of the sludge breaks down at a normal value pH I have an important role to play, so that I will not be able to effectively overtravel the bricks in the minds of a person who has a good idea of ​​going into a slurry.

Pepsin-B (parapepsin I, gelatinazi)- a proteolytic enzyme, activates for the participation of calcium cations, turns into pepsin and gastrointestinal cells more and more gelatinous for with good fabrics, - gelatin) і we turn less on hemoglobin. See also pepsin A - cleansing product, removal from the mucous membrane of the pig's slurry.

There is also a small amount of lipase before the storage of slurry juice, because of the breakdown of emulsified fats (triglycerides) to fatty acids and diglycerides at neutral and weakly acidic values. pH(5.9-7.9). In infants, the slunk lipase breaks down more than half of the emulsified fat, which can enter before the breast milk store. In older people, the activity of shlunkovaya lipazi is low.

The role of hydrochloric acid in etching:

  • aktivuє pepsinogen slung juice, converting їх into pepsin;
  • sour sour middle, optimal for diy enzymes in slunk juice;
  • vicious swelling and denaturation of the bile, which lays down and over-etching;
  • I can get bactericidal,
  • I regulate the spinning of breeze juice (if pH Vantral viddili slunk stag mensh 3,0 , Secretion of slurry juice is starting to galmuvatisya);
  • we put a regulating inflow on the motility of the slunker and the process of evacuating the slunker in the intestine (with a decrease pH in the twelve-fingered intestines, it is possible to perform the galvanizing of the motor function of the slunker).

Slurry juice slurry function

The mucus, which should enter the storage of the sludge juice, at the same time with the ions of HCO - 3 solidifies the hydrophobic viscous gel, which will entrap the mucus from a high concentration of hydrochloric acid and pepsin.

Shlunkova slime - a component instead of a slurry, which is stored in glycoproteins and bicarbonate. An important role is played by the mucous membrane in the form of hydrochloric acid and enzymes in the secretion of mucus.

A special gastromucoprotein should enter the storehouse, which is fixed by the shafts of the bottom of the slunk. Castle's internal factor, Which is necessary for the povnotsinny soaktuvannya vіtamіnu В 12. Win calls with vitamins В12. go to the drain in the storehouse, oberigє yogo from ruinuvannya and spriy to mooktuvannyu tsyogo vіtamіnu v. Vitamin B 12 is necessary for normal blood formation in the heart cystic brain And for the correct maturation of blood cells.

Nastach vіtamіnu V 12 in the internal middle organism, dressing with wreckage yogo wіmoktuvannya through nessacha internal official Castle, to be spared in case of a visible part of the slunk, atrophic gastritis, and to lead to the development of an important ailment - In 12-deficit anemia.

Phases and mechanisms of regulation of the slunk secretion

On the other hand, the heart of the shlunkovye has a small amount of shlunk juice. Acceptance of shlunkovy secretion of sour shlunkovaya juice with a lot of ferments. I.P. Pavlov divided the entire period of the secretion of the shlunk juice into three phases:

  • complex reflex, or mozkov,
  • shlunkovu, or neurohumoral,
  • gut.

Brain (complex reflex) phase of the secretion of the slunk - making the secretion more powerful, enveloping with the reception of the їzhі, the appearance and the smell, flowing into the receptor of the mouth and the pharynx, with the acts of chewing and kovtannya (stimulated by mental reflexes, like supervising with the reception of the uzhі). Presented in the past with the explicit years of I.P. Pavlova (an esophagous dog with an isolated slurry, which took an innervating), didn’t use the slurry in the slurry, but rather spared the ryasna slurry secretion.

complex reflex phase The slurry secretion must be repaired before being consumed in the empty mouth when looking at the mouth and preparing for the first time and when the taste, tactile, temperature receptors of the mouth emptying are teased. Stimulation of shlunkovaya secretion in the qu phase cleanseі crazy reflexes As a result of a series of clever pals (sight, smell, environment) on the receptor of organs of the sentiment and of a mad prankster (їzhі) on the receptor of the mouth, pharynx, stravohodu. Afferent nerves, impulses from receptors, stimulate the nuclei of the bloating nerves in the large brain. Distant along the eferent nerve fibers of the bloating nerves of the nerves, the impulses reach the mucous slurry and stimulate the slunk secretion. Intersection of the bloating nerves (vagotomy) will increase the secretion of the shlunkovaya juice in the ci phase. The role of insane reflexes in the first phase of shlunkovaya secretion demonstrates the awareness of the "explicit year", the proponations of I.P. Pavlovim in 1899, Sobatsi carried out an operation of an esophagus in front of the front (rerouting the strato-void with overflowing sieve on the surface of the shkiri) and laid a slurry fistula (a piece obtained from the middle of the emptying organ. During the year of bathing, the dogs were wiped out, the hedgehog vipadal with the overrun stravohode and did not fit into the drain. However, after 5-10 minutes after the ear of a clear year, it meant that the sour shlunk juice was introduced through the shlunkovuyu fistula.

Shlunkovy sik, which is secreted in the complex reflex phase, to avenge a large number of enzymes and a large number of enzymes are necessary for normal etching into the slurry. I.P. Pavlov called tsey sik "ignite". Shlunkov secretion in the complex-reflex phase is easy to show off in the presence of other third-party infusions (emoticons, large injections), which negatively inflows into the etching process into the slunk. Galmіvnі fusion realіzuyutsya with awakening sympathetic nerves.

Shlunkov (neurohumoral) phase of shlunk secretion - Growth of secretion, how to wick without a middle stage (products of hydrolysis of bilks, a number of extractive fluids) on the slime of the slurry.

shlunkova, abo neurohumoral, phase the slurry secretion to be repaired when the slurry gets into the slurry. Regulation of secretion in the ciu phase of good health nervously reflexive, so i humoral mechanisms.

Small. 2. Scheme of the regulation of the activity of the lining of the slurry, which will prevent the secretion of ions in water and the establishment of hydrochloric acid

Revitalization of the mechano, chemo and thermoreceptors of the mucous membrane of the shlunk vyklicaє flow of nerve impulses along the afferent nerve fibers and reflexively activating the head and lining cells of the mucous membrane of the shlunk (Fig. 2).

It was established before the last path that vagotomy did not assimilate the shlunkovy juice secretion in the tsyu phase. Price information humoral factors, Scho pidsilyuyut shlunkovu secretion. With such humoral words є hormones shlunkovo-intestinal tract gastrin and histamine, which are produced by special cells of the slime slurry and are more enriched by the secretion of the head of hydrochloric acid, and in the smallest world they stimulate the production of enzymes in slush juice. Gastrin It was necessary to use G-cells of the antral form of the slurry when it was mechanically stretched, by pouring in the products into the hydrolysis of the proteins (peptides, amino acids), as well as the destruction of the bloody nerves. Gastrin comes into the bloodstream and into the lining of the bed endocrine path(Fig. 2).

products gistamina zdіysnyuyut special cells of the bottom of the slunk before the infusion of gastrin and in case of damaged bloody nerves. Gistamin does not enter the bloodstream, but rather stimulates the rosetting of the cladding cells (paracrine action), which produces a great amount of acidic secretions, which are not enzymes and mucin.

There is an effective impulse, which comes along the bloating nerves, either directly or indirectly (through stimulation of gastrin and histamine production), pouring into the increase in the amount of hydrochloric acid and obsolete cells. The head cells, which produce enzymes, are activated by parasympathetic nerves, and without the need for an infusion of hydrochloric acid. A mediator of parasympathetic nerves, acetylcholine, increases the secretory activity of shlunkovye zoloz.

Small. Osvita hydrochloric acid in the lining plate

The slurry secretion in the slurry phase can also be deposited in the warehouse of the accepted їzhі, evidently in the new hospitality and extractive chan- nels, which are significant for the slurry secretion. There is a great number of extractive speeches to be found in meat broths and vegetable broths.

With a trivial implantation, it is important in the carbohydrate їzhі (hlib, vegetables) the secretion of slunk juice changes, with the implantation of їzhі, rich bites (meat), - growth. Injecting the mind into the slunk secretion is of practical importance in case of deyaky illnesses, which supervise the deterioration of the secretory function of the slunk. So, with the hypersecretion of shlunk juice, she is guilty of butti meat, ogorta consistency, with the swirling buffer powers, she is not guilty of revenge of extractive speeches of meat, gostrich and hot spices.

Intestinal phase of the slurry secretion- stimulation of the secretion, which occurs when it is necessary in the intestine instead of the slunk, and is triggered by reflex infusions, which are detected when the receptors are subdivided in the twelve-fingered intestine, and humoral injected into the intestines. Ї with the help of gastrin, and the correct sour їzhі (pH< 4), жира — тормозит.

intestinal phase shlunkovaya secrets to obey in the course of evacuation grub from a slunk in two to twenty digits of the intestine and to carry koriguyuyu character. Stimulating and galvanic fusion from the twelve-fingered intestine onto the slurry zone is realized through neuro-reflexive and humoral mechanisms. With the subdivision of mechano- and chemoreceptors of the intestine by products of hydrolysis of the bile, which were taken out of the shlunk, muscle galvanic reflexes are triggered, the reflex arc which freezes without an average in the neurons of the nerve spinal cord However, the greatest value in the whole phase is humoral mechanisms. With the correct sour in the place of the slunk in the intestine two to twenty pHїї vmistu mensh 3,0 klitini mucus viroblyayut hormone secretin, Scho galmu production of hydrochloric acid. An analogous grade for the juice separation of the slurry inletє cholecystokinin, Establishment of something in the intestinal mucosa to be consumed for injected products into the hydrolysis of bile and fat. However, secretin and cholecystokinin produce pepsinogen products. In the stimulation of the mucus secretion in the intestinal phase, it takes a role for the products of hydrolysis of proteins (peptides, amino acids) to soak into the roof, which can stimulate the mucous membranes without an average or stimulate the appearance of gastric growth.

Method of vivchennya shlunkovaya secretion

For the advancement of slunk secretion in people, they use probes and bezondovis methods. probe The slunker allows the viscosity of the slunk juice, its acidity, instead of enzymes in the heart, and with stimulation of the slunk secretion. In the capacity of the stimulants in the vicoristovy, meat broth, sprinkle vidvar, and various chemical words (synthetic analogue of gastrin pentagastrin or histamine).

Acidity of shlunk juice For the evaluation of the change in hydrochloric acid (HCI) and a small amount of milk in decinormal sodium hydroxide (NaOH), which is necessary for neutralization of 100 ml of slurry juice. The acidity of the slurry juice shows the amount of dissociated hydrochloric acid. Zagalny acidity characterizes the total amount of combined hydrochloric acid and other organic acids. Have great people On the other hand, the natural acidity of the heart becomes 0-40 tons of units (i.e.), the acidity is 0-20 tons. For submaximal stimulation with histamin, the acidity becomes 80-100 units, the acidity becomes 60-85 units.

Widely expanded special thin probes, without sensors NS, For the help of those you can restore the dynamism of the snake pH without the middle in the empty slunk by pulling it out ( pH meter)) wiry ailment... Prior to probeless methods to be applied method of endoradiation the herbal tract, when there is a special radio capsule, we get sick, move along the herbal tract and transmit signals about pH in new yogo viddilakh.

Slink motor function and mechanics and regulation

The motor function of the slider is smooth and smooth. It is safe to relax when taking in the slurry (adaptive grub relaxation), so that it allows you to deposit a lot of money (up to 3 years) without a lot of money. With fast smooth muscles of the slunk, mix it with slunk juice, as well as refinement and homogenization in place, as it ends with the solutions of the same generation. Portal evacuation of the chimus from the slurry into the twelve-fingered intestine is discharged with fast smooth cells of the antral slurry and the weakened pyloric sphincter. Adequate portions of sour chimus with a slurry in the intestine, lowering the pH of the intestine, reduce the intestinal pH to the destruction of the mechano-and chemoreceptors in the mucous intestine and viklikal reflex of the intestinal hyperemia. At the same time, the antral viddil of the shlunk relaxes, and the pyloric sphincter speeds up. It is necessary for a chimus port to come into the intestine two to twenty five pHїї to update.

On the efficiency of evacuation of chemistry from the slurry into the twelve-fingered intestine, the physical and chemical authorities of the society are injected. It’s better for everything to leave the slunker, to take revenge on the carbohydrates, then to take revenge on the carbohydrates, at that hour it’s fatty to go into the slurry for more than a trivial hour (up to 8-10 years). Sour and sour is given to more general evacuation of the slurry due to a neutral or neutral reaction.

Regulation of the motor skills of the slunker neuro-reflexі humoral mechanisms. Parasympathetic bloody nerves will enhance the motor skills of the slunk: increase the rhythm and strength quickly, the speed of peristalsis. With the stimulation of the sympathetic nerves, the galvanization of the motor function of the slunk is promoted. The hormone gastrin and serotonin wicks to increase the mucus activity of the slunker, at that time the secretin and cholecystokinin galvanize the slunk motility.

Bluvota is a reflexive ruddy act, as a result of which instead of the slunk it wicks through the stravohid into the empty company and comes to the end of the middle. It will take care of the fast-flowing meat of the slurry shell, the muses of the anterior cranial wall and diaphragms and the weakening of the NSS. Bloating is often a toxic reaction, behind the help of which organism is caused by toxic and branched speech, which was consumed in the intestinal tract. However, there can be no mother when dear ones herbal tract, intoxications, infections. Vinnik's blues reflexively in case of damaged blooming center dovzhastogo brain afferent nerve impulses from the receptors of the mucous membrane of the root of the tongue, pharynx, shlunk, intestine. Call the act of blues before seeing boredom and more than dreaming. The stimulation of the bluetongue center with the onset of bluetongue can be found in the case of teasing scent and relish receptors words, wiklikayut feeling like ogidi, receptors in the vestibular apparatus (before an hour go by car, sea roads), when there are some Lykarskiy rechovin to the bluework center.

Shlunkovy sіk of the fundal part is stored z (99-99.5%), shilnye speeches(0.3-0.4%) і mineral salts (chloride, nitric acid salts, phosphate, sulfate), hydrochloric acid (0.4-0.5%); The pH of pure slurry juice of humans can be adjusted from 1.0 to 2.5. The acid is active and the swelling of the bile acids, which lays down on them with enzymes. For people, 1.5-2 dm 3 of juice is added to it; for a horse - up to 30 dm 3. When bathing, the amount of slurry juice decreases, and when bathing in carbohydrates it changes.

At the warehouse for juice and ferments:

1. Pepsin is a proteolytic enzyme, hydrolysis of protein to albumen and peptones, which digests meat proteins more readily and is more significant than milk protein. Pepsin is established from pepsinogen when it is fed with hydrochloric acid and shlunk juice; take revenge in the slunk juice of people and tvarin. Optimum proteolytic action of pepsin at pH 1.5 - 2.0.

2. gastric. The more active the pepsin, the more light-colored block will over-poison the weaker. Proteolysis, vibration of the volume with enzymes, which is not less than 95%, the ratio between them is one from 1: 1.5 to 1: 6; Take revenge in the slunk juice of the people. The maximum activity is at pH 3.2.

3. Pepsin B, or parapepsin. Pretend to be a pair of pepsinogen.

4. Rennin, a ferrous enzyme, or chymosin (found in a great quantity of suckers, especially calves), curdling milk, wiping out a bottle of casein in a non-essential form. Looseness of the bunch of sludge. Dіє in neutral, slightly acidic і puddle middle.

In slurry juice, there are also non-proteolytic enzymes: lipase-enzyme, which breaks down emulsified fat, amylene, which breaks down in carbohydrates, lysozyme, which has a healthy bactericidal function, i.e. E. Oh little. In children, lipase is activated by the enzyme lipokinase.

There is a small amount of pepsinogen to pass in and out in the cut.

Pyloric shlunkovy syk is easy reaction (pH). Win to take revenge on the same ferments, albeit in the smallest number and even in the lush middle. The digestive power is 4 times less than the over-etching of the fundic juice. Pepsin of pyloric juice is over-etched with tissue fibers.

Pepsin can also be found in the juice of the cob (Brunner's) intestines. The digesting power of shlunk juice in the whole form is 5 times less than the fundus; how to take revenge in new pepsin di in a sour middle and overtraveling from semi-tissue bottles.

Slough the slime shell of the slurry to release, crush the juice, slime, I will play the role, and will keep the slime shell of the slurry from mechanical and chemical ears. In addition, lick breasts accumulate ferment (adsorb) on their surface, so that they can digest them.

In normal physiological minds of the shlunks, the presence of antiferment does not self-digest. Slide vvazati, how ferment can not expand the blocks of living cells, but make its own difference only on denaturing the blocks. Water and hydrochloric acid, which collapses to the mucous membrane of the slunk, can be zruynuvati. Ale їkh penetration of the pereshkojaє bar'єr of the high cylindrical epithelial cells of the mucus, as well as the protolezhny straightening of the rukh іonіv sodium from the blood-bearing vessels.

In people over 20 years, the amount of slunk juice naturally decreases, instead of that of new enzymes and hydrochloric acid.

Inflow to the warehouse of slunk juice

People have a small amount of juice to be seen without interruption, even at night that vrantse secret becomes minimal or lean. There are also individual add-ons of secrets, which lie in the minds and in the nature of food and drink. People have more reflexive reflexes on the secretion of the turn more, less from creatures. Naybіlsh strong sludge secretions: chlіb, meat broth and kapustaniy vіdvar. In dogs, during the daytime and grubbing, the slug does not appear, and the slime of the slunk is covered with puddled mucus.

At laboratory I. P. Pavlova on dogs with a small slunk was installed, but on the skin-like appearance, it is not stale from the depleted slurry є the singing movement of the slurry juice, that is, the gross amount, the digesting force and acidity.

In dogs, the juice for meat should be repaired after 8 minutes for the cob, and after 6 minutes for bread. The most amount of juice is used for meat, sometimes for bread and the least for milk.

The amount of juice, seen for the entire herbal period, is directly proportional to the amount of the season.

Most of the great speeches can be found in juice for bread, the least - in juice for milk, juice for meat is borrowed in the middle of the day. So, as the digesting power of juice is greater, more than in new chilny speeches, then the most powerful overtraveling of power from the sorts of small shlunkovy sik, emerging in the case of chiliba. Fermenting ferment for їzhі khlіba - starch.

The most amount of juice was most over-poisoned, and it was seen with meat and bread in the 1st year, and with the milk - in the 2-3rd year.

A great deal of juice was given for bread, more for meat and nareshty, for milk.

With high fat, two prototypes are prevented. In the first phase, for a period of 2-4 years, the intake of fat will change, or there will be an increase in the intake of the slurry secretion. The other phase is perceived as a weak over-poisoning.

Horses have the greatest amount of juice when they have cabbage, less when they have sina, and even less when they are hungry. In pigs, the most amount of juice is used for forage silage.

Innervatsion of slunk beds

The appearance of the їzhі, її smell і, tied to the closeness, wicks reflexively to the juice of the slunk vines.

The introduction of shlunk juice in the past with obvious years on esophagous dogs; Slurry slug is produced for an hour and in dogs with an isolated slurry. Induction of slurry juice is also promoted in people from the slurry fistula, which is damaged due to the lack of durability of the trawler, when shown to the act of death. So, as a last resort, the shlunkovy sik appears when the receptors are subtitled mouthwash If the pharynx is not consumed in the slunker, then the result is reflex.

The cei reflex can be detected in dogs against measles great pіvkul, Otzhe, vin є insane, innate reflex (G.P. Zeleniy, 1911, 1912).

The effective impulses are directed to the corkscrews along the bloody nerves (I. P. Pavlov і Shumova-Simanovskaya. 1890).

During the period of overwhelming both bloody nerves in the country during the early years and teasing people in the country do not wipe out the slurry juice. The core of the fibers, which secretes the slunk juice, is stored in the storage of the bleeding nerves, and also the fibers that galvanize the secretion.

Fibers, which galvanize the secretion, are found in the cute, celiac nerves, in which, with good minds, it is possible to evolve and fibers, so that the secretion is wicked.

Emotions, scho zbudzhuyut bloody nerves, podsiluyuyut secretion of shlunk juice, and awesome cute nerves - galmatize її. The nerves of the slunker are squeezed out of the juice and the warehouse. Bloody nerves will help you see the slime, so you can see it without interruption. Nice nerves to improve awareness and vision of enzymes. The small curvature of the shlunk is more secured by the fibers of the flaky nerves, the lower is the great curvature, the rest, the navpaki, and more, the fibers of the sympathetic nerves.

Reflexively, the fat is going to be the head rank reflexively, as it is significant to change as the overwhelming nerves become overwhelmed.

Mechanical subtlety of the mucous membrane of the fundal part of the shlunk vyklica vyclinny shlunkovy juice (S. I. Chechulin, 1934). There is no reflex secretion of juice, so as to overreach the bloating nerves, it is easy to lean back. However, in case of repeated positive mental reflexes, a lot of mechanically teasing the slunk with a humic balloon, or even in small dogs, and in non-dog dogs, the secretion of the fundal zalosis (M. M. Pavlov, 1958)

Mechanical and chemical subtlety of the receptors in the mucous membrane of the wicklack slunk nerve cells, Imprisoned in the walls of the shlunk, ale іnnuyut and reference reflexes on the muck nervous system... In the event of an obvious period of time, it is caused by the development of the peripheral problems of the bloody nerves. With such a rank, you can secure your innervations with your equipment.

At the place of calm in the slunk of a man (without a reception) there is 50 ml of basal secretion. The price of sludge, shlunkovaya juice and inodi zakidannya from the duodenum. For the dobu, you should be close to 2 liters of slunk juice. The center of the hole is an opalescent line with a thickness of 1.002-1.007. Little acid reaction, fragments є hydrochloric acid (0.3-0.5%). Ph-0.8-1.5. Hydrochloric acid can be found at the base and at the link with the bottle.

Shlunkovy sic can also take revenge on inorganic speech - chlorides, sulfates, phosphates and sodium bicarbonates, calories, calcium, magnesium.

Organic speech is represented by enzymes. The main enzyme of the slurry juice is chain pepsin (protease, which is used for drinks) and lipase.

Pepsin A - ph 1.5-2.0

Gastrixin, pepsin C - ph-3.2, 3.5

Pepsin B - gelatinase

Renin, pepsin D chymosin.

Lipaza, diє for fat

All pepsins are seen in inactive forms in pepsinogen. The infection is proposed to divide pepsin into groups 1 and 2.

pepsin 1 only visible in the acid-forming part of the slime slurry - de є cladding cells.

Antral part and piloric part - pepsin is seen there groupie 2... Pepsin will be over-etched to industrial products

Amilaza, yak, eat it with saline, spill it into the slurry for maybe an hour, until the ph is found in the sour haystack.

The main component of shlunk juice is water - 99-99.5%.

An important component is hydrochloric acid.

  1. Vona spriya is the transformation of the inactive form of pepsinogen into the active form - pepsin.
  2. Hydrochloric acid is the optimal ph value for proteolytic enzymes
  3. Viklikє denaturation and swelling of bіlkіv.
  4. The acid can be used as an antibacterial agent and bacterium as it is put into the slurry.
  5. Participates in the education and hormone - gastrin and secretin.
  6. Milk dissolves
  7. Take part in the regulation of the transition from the cork to the duct

Hydrochloric acid to pretend to be in the lavish clitines. Price to reach great clients of the paramedal form. In the middle cych cells - a great number of mitochondria, the stench to replace the system of internal tubules and from them tightly tied the bulb system in the form of vesicles. The vesicles ring with the tubular part during activation. The canaliculi have a large number of microvilli, which increase the area of ​​the surface.

The study of hydrochloric acid and the intratubular system of the lining clitin.

On the first stage the transfer of anion to chlorine into the duct is seen. They come to chlorine through a special chlorine channel. The canaliculi have a negative charge that attracts internal cells.

On the offensive stage the exchange of calories for proton water, for the active transport of water for the amount of ATPase. Kaliy exchange for proton water. For the help of the pump, the inner wall is pumped. In the middle of the cells, the acid is dissolved. Vona accept the results of the interaction in carbon dioxide and drive for the rakhunok of carbonic acid. Vugilic acid is dissociated to proton water and anion HCO3. The proton is exchanged for calium, and the anion HCO3 is exchanged for chlorine. Chlorine is added to the lining sheet, as soon as it goes into the tubule lumen.

The lining cells have one more mechanism - sodium - calcium ATPase, which is used to bring sodium from the cells and turn sodium.

The process of setting up hydrochloric acid is an energetic and nitrate process. ATP takes root in mitochondria. The stench can take up to 40% of the oblique clitin. Concentration of hydrochloric acid in the tubules of the arch of the temple. Ph in the middle of the tubule up to 0.8 - the concentration of hydrochloric acid and 150 ml mol per liter. Concentration of 4,000,000 food in plasma. The process of setting hydrochloric acid in the lining cell is regulated by pouring acetylcholine onto the lining cell, which is seen in the ends of the bloating nerve.

Climate rooms Mayut cholinoreceptorsі stimulate the adoption of HCl.

gastric receptorі the hormone gastrin can also activate the release of HCl, moreover, it is necessary to pass through the activation of membrane proteins and the release of phospholipase C і to establish inositol-3-phosphate and to stimulate the mechanism of calcium reduction by combustion.

3rd type of receptors - histamine receptorH2 ... Гістамін viroblyaєtsya in the shlunks in the center-chromium ogryadnye cells. Gistamin din on the H2 receptor. Here the injection is realized through the adenylate clase mechanism. Adenylate cyclase is activated and cyclic AMP is established

Galmuє is a somatostatin, which can be found in D cells.

Hydrochloric acid- the main factor in the reduction of mucous membranes in the case of a damaged shell. Likuvannya gastritis - suffocation of hydrochloric acid. The antagonism of histamine - cimetidine, ranitidine, blocking the H2 receptor and decreasing the level of hydrochloric acid - is even more widespread.

Suffering water-kaliy ATFazi. Bulo otrimano speech, yak є pharmacological drug omeprazole. Wine brings water-caly to ATPase. Tse duzhe m'yake diyu, reduce the amount of hydrochloric acid.

Mechanisms for regulating slunk secretion.

The process of shlunk etching is cleverly added to 3 and one to one phases

  1. Foldable reflexive - mozkova
  2. shlunkova
  3. kishkova

Inodi 2 remain in the neurohumor.

Foldable reflex phase... Surrounded by the destructions of creeping valleys with a complex of insane and intellectual reflexes, tied together with the reception of the forest. mind reflexes to be judged by the subtle scent, healthy, auditory receptors, by the sight, the smell, by the situation. Tse cleared signals. They will be superimposed on the pouring of podraznikiv onto the empty company, the pharyngeal receptor, the stravohode. Tse crazy razdratuvannya. The same phase of Pavlov and vivchav in the end of the imaginary year. Latent period from the ear of the year is 5-10 quills, so that the slurry starts to turn on. Pislya pripinennya godovannya - secretion is trivial 1.5-2 years, as long as you don’t eat it in the slurry.

The secretory nerves will be bloody. It is through them itself that the inflow is pumped onto the cladding cells, which are used to circulate hydrochloric acid.

bloody nerve stimulation of gastric cells in the antral appearance and acceptance of gastrin, and D cells, de-viroblyayutsya somatostatin to galvanize. Bulo was revealed, on the gastric cell vagus through the mediator - Bombesin. Tse zbuzhuh gastrinovogo klitini. On D cells, for the production of somatostatin wine is brought. In the first phase of the shlunkovaya secretion - 30% shlunkovaya juice. Win Volodya with a high acidity, over-etching strength. Meta pershoi fazi - gotuvati shlunok to priyomu uzhi. If you have consumed the shlunkovaya phase of the secretion. When you have a lot of food instead of mechanically stretching the slurry walls and getting sensitive endings of blinking nerves, as well as sensitive endings, as approved by the clientele of pid-muffin gossip. At the slunker, there are micevs reflex arcs... Doggel's cell (sensitive) sets up a receptor in the mucous membrane and when it is stimulated, it is generated and transmitted to the cell of the 1st type - secretory or motor. Winikє local muscle reflex and zalosa startє pratsyuvati. Clitini of the 1st type і і post-ganglionaramі for the blukus nerve. Bloody nerves trim under control of humoral mechanism. Immediately, with a nervous mechanism, a practical humoral mechanism is started.

humoral mechanism dressings from the vision of Gastrin G cells. The stench vibrates 2 forms of gastrin - from 17 amino acid surpluses - "maliy" gastrin and another form of 34 amino acid surpluses - great gastrin. Maliy Gastrin Volodya is more powerful than the Great Gastrin in the blood. Gastrin, which can be used to prepare cells and food on cladding cells, stimulating the adoption of HСl. Win the same day and on the cladding rooms.

The function of gastrin is stimulating the secretion of hydrochloric acid, stimulating the fermentation of the enzyme, stimulating the motility of the slunk, which is necessary for the growth of the mucous membrane of the slunk. Also, I stimulate the vision of the juice of the slurry. Vibrating gastrin is stimulated not only by nervous factors, but also by food products, which are approved for the hour of splitting and also by stimulants. Before them, the products of the breakdown of wine, alcohol, cava - coffee and non-coffee are introduced. Vibrate hydrochloric acid and lay it in ph at a lower ph lower than 2x, asphyxia virovaniya hydrochloric acid. Tobto tse is tied with this, that is, the concentration of hydrochloric acid and galmu viroblenya gastrin. At the same hour, the end of the concentration of hydrochloric acid and the activation of somatostatin viroblast, and the vitriolation of gastrin. Amino acids and peptides can be consumed without a middle day on the lining cells and produce the secretion of hydrochloric acid. Bilky, volodyucha with buffer powers, tie a proton to water and to provide the optimal level of acidity

Shlunkovu secretion pіdtrimє intestinal phase... If the chyme reaches 12 pounds, then the wine is poured into the shlunkovaya secretion. 20% of the shlunk juice is circulated in the qi phase. At nіy enterogastrіn are viroblyayutsya. Enterooxintin - the hormones are circulated before the HCl, when the slurry goes into the duodenum, before the amino acids are injected. If the acidity of the middle in the duodenum will be temporal, then there is a suppression of stimulating hormones, and enterogastron is violated. One of the species in the future is GIP - gastrointestinal peptide. Wine galmonic acid and gastrin. Bulbogastron, serotonin and neurotensin can also be added to galleys. On the side of the 12 palate intestine, there can be winy and reflexive injections, which stimulate the bloating nerve and turn on the muscular nerves of gossip. In general, the view of the shlunk juice will be deposited as a quantity of yakosti. The amount of slurry sap should be kept at the hour of the transfer. In parallel with the growth of juice, the acidity increases.

The digesting power of the juice is greater in the first year. For the assessment, the juice of the proponation was overtrained Ment's method... Fatty їzha drives shlunk secretion, so it is not recommended to take fatty їzhі on the cob. Do not give stars to children rib fat to the ear of a їzhі. Acceptance of fat in front of it - reduces the amount of alcohol that is soaked in the slunk.

Meat is a white product, hlib is a rosin and milk - zmishany.

for meat- to see the maximum amount of juice with the maximum secrecy for another year. With the maximum acidity, it is not enzymatic. Shvidke growth of secretion is surrounded by strong reflex teasers - a sight, a smell. Then, for the maximum secretion, the decrease is reduced, the decrease in the secretion of everything. A high amount of hydrochloric acid and will prevent denaturation of the bottle. Residual cleavage is found in the intestines.

Secretion for hlib... The maximum is to reach the first year. Shvidke nastostannya is tied with a strong reflex teaser. Having reached the maximum of the secretion to reach the shvidko fall, there are few humoral stimulants, ale secretion is trivial (up to 10 years). Enzymatic health - visoka - acidity is mute.

Milk is the main source of secretion... Weakly subtle receptors. Revenge of fat, secretion of galmyt. Another phase, when the maximum is reached, is characterized by a steady decline. Here, fat breakdown products are established, which stimulate secretion. Enzymatic activity is non-viscous. It is necessary to live vegetables, juices and mineral water.

Secretory function of pidshlunkovoy zalozi.

The chyme, which comes in the 12th of the intestine, is fed to the slurry juice, gut and intestinal juice.

Pidshlunkova zalosa- the best value. I have a subordinate function - intrasecretory - insulin and glucagon and general secretory function, which will prevent the circulation of pancreatic juice.

Pidshlunkovoy sіk establish itself in the zalose, in the acinus. Yak visteleni perehidnymi cells in 1 row. Cich cells have an active process of setting up enzymes. They have a good endoplasmic border, Aparat Goldzhi and from the acinus repair the ducts of the subshlung zone and set up 2 ducts, which can be found in the 12 intestine. The smallest duct - Wirsung duct... It is seen in place with the gum duct in the area of ​​the Vater's nipple. Sphinkter Oddi is located here. Another dodatkovy duct - Santorini ascend proximal to the Versungian duct. Vivchennya - an overlay of f_stul on 1 channel. In humans, it is not possible to get implanted by the probe method.

In his own way warehouse for slurry- a glimpse of a barnless line of reaction. The quantity is 1-1.5 liters for extra water, ph 7.8-8.4. The same storehouse of calories and sodium is the same in plasma, a little more than ionic bicarbonate, and Cl less. In the case of acinus, it is also possible to create juice along the ducts in the world before the cells of the ducts will not be tanned in chlorine and some in bicarbonate will be consumed. Enzyme storage

Proteolytic enzymes, which are used for bins - endopeptidase and exopeptidase. The difference is that endopeptidases work on the internal link, and exopeptidases split off endopeptidase amino acids.

Endopepidazi- trypsin, chymotpsin, elastase

Ectopeptidazi- carboxypeptidase and aminopeptidase

Proteolytic enzymes are circulated in an inactive form - a ferment. Activation of vidbuvatsya before the enterokinase. Vona active trypsin. Trypsin is seen in the form of trypsinogen. And the active form is trypsin active іnshі. Enterokinase is an enzyme of intestinal juice. In case of blockages of the duct, it is possible to activate the activation of enzymes in the middle of it with alcohol implantation. To fix the process of self-digestion of pidshlunkovoy zalozi - gostry pancreatitis.

on carbohydrate diet of aminolytic enzymes -alphaamylase, breaks down polysaachridi, starch, glucogen, cannot break down cellulose, from solutions of maltose, maltothiose, and dextrin.

fat litholytic enzymes - lipase, phospholipase A2, cholesterol. Lipase for neutral fats and breaks down to fatty acids for glucerin, cholisterinesterase for cholesterol, and phospholipase for phospholipid.

fermentation on nucleic acids- ribonuclease, deoxyribonuclease.

Regulation of slurry filling and secretion.

Vona is tied to the nervous and humoral mechanisms of regulation and the inclusion of the slurry in 3 phases

  1. smoothly reflexive
  2. shlunkovu
  3. gut

Secretory nerve - bloody nerve, Yakiy dіє on fermentation of enzymes in cells of acini and on a cell of ducts. The infusion of pretty nerves on the pidshlunkovu is not, albeit pretty nerves, the blood flow decreases, and the secretion changes.

Great value of maє humoral regulation pidshlunkovoy zalozi - education of 2 hormones of the mucous membrane. In mucous membranes єC cells, which vibrate the hormone secretin and the secretin gets wet at the roof of the wine on the cellin the duct of the pidshlunkovaya zalozi. Stimulates cellini for hydrochloric acid

2nd hormone is violated by I cells - cholecystokinin... In the development of a secretin on the acidic acid cells, the amount of juice will be less, a little bit more with enzymes and the production of type I cells from the diet of amino acids and in the smaller world of hydrochloric acid. Інші hormones are working on a podshlunkovy zalozu - VIP - nadaє dіyu, I go with secretin. Gastrin is similar to cholecystokinin. In the complex reflex phase, the secretion is seen 20% of the sludge, 5-10% of the attack on the shlunkovaya, and the sieve in the intestinal phase, and the slurry zloza is on the offensive stage, inflowing the shlunkovaya juice, the vyroblenya of the shlunkovaya juice is still firmly connected. When gastritis develops, then pancreatitis follows.

At the place of calm in the slunk of a man (without a reception) there is 50 ml of basal secretion. The price of sludge, shlunkovaya juice and inodi zakidannya from the duodenum. For the dobu, you should be close to 2 liters of slunk juice. The center of the hole is an opalescent line with a thickness of 1.002-1.007. Little acid reaction, fragments є hydrochloric acid (0.3-0.5%). Ph-0.8-1.5. Hydrochloric acid can be found at the base and at the link with the bottle.

Shlunkovy sic can also take revenge on inorganic speech - chlorides, sulfates, phosphates and sodium bicarbonates, calories, calcium, magnesium.

Organic speech is represented by enzymes. The main enzyme of the slurry juice is chain pepsin (protease, which is used for drinks) and lipase.

Pepsin A - ph 1.5-2.0

Gastrixin, pepsin C - ph-3.2, 3.5

Pepsin B - gelatinase

Renin, pepsin D chymosin.

Lipaza, diє for fat

All pepsins are seen in inactive forms in pepsinogen. The infection is proposed to divide pepsin into groups 1 and 2.

pepsin 1 only visible in the acid-forming part of the slime slurry - de є cladding cells.

Antral part and piloric part - pepsin is seen there groupie 2... Pepsin will be over-etched to industrial products

Amilaza, yak, eat it with saline, spill it into the slurry for maybe an hour, until the ph is found in the sour haystack.

The main component of shlunk juice is water - 99-99.5%.

An important component is hydrochloric acid.

  1. Vona spriya is the transformation of the inactive form of pepsinogen into the active form - pepsin.
  2. Hydrochloric acid is the optimal ph value for proteolytic enzymes
  3. Viklikє denaturation and swelling of bіlkіv.
  4. The acid can be used as an antibacterial agent and bacterium as it is put into the slurry.
  5. Participates in the education and hormone - gastrin and secretin.
  6. Milk dissolves
  7. Take part in the regulation of the transition from the cork to the duct

Hydrochloric acid to pretend to be in the lavish clitines. Price to reach great clients of the paramedal form. In the middle cych cells - a great number of mitochondria, the stench to replace the system of internal tubules and from them tightly tied the bulb system in the form of vesicles. The vesicles ring with the tubular part during activation. The canaliculi have a large number of microvilli, which increase the area of ​​the surface.

The study of hydrochloric acid and the intratubular system of the lining clitin.

On the first stage the transfer of anion to chlorine into the duct is seen. They come to chlorine through a special chlorine channel. The canaliculi have a negative charge that attracts internal cells.

On the offensive stage the exchange of calories for proton water, for the active transport of water for the amount of ATPase. Kaliy exchange for proton water. For the help of the pump, the inner wall is pumped. In the middle of the cells, the acid is dissolved. Vona accept the results of the interaction in carbon dioxide and drive for the rakhunok of carbonic acid. Vugilic acid is dissociated to proton water and anion HCO3. The proton is exchanged for calium, and the anion HCO3 is exchanged for chlorine. Chlorine is added to the lining sheet, as soon as it goes into the tubule lumen.

The lining cells have one more mechanism - sodium - calcium ATPase, which is used to bring sodium from the cells and turn sodium.

The process of setting up hydrochloric acid is an energetic and nitrate process. ATP takes root in mitochondria. The stench can take up to 40% of the oblique clitin. Concentration of hydrochloric acid in the tubules of the arch of the temple. Ph in the middle of the tubule up to 0.8 - the concentration of hydrochloric acid and 150 ml mol per liter. Concentration of 4,000,000 food in plasma. The process of setting hydrochloric acid in the lining cell is regulated by pouring acetylcholine onto the lining cell, which is seen in the ends of the bloating nerve.

Climate rooms Mayut cholinoreceptorsі stimulate the adoption of HCl.

gastric receptorі the hormone gastrin can also activate the release of HCl, moreover, it is necessary to pass through the activation of membrane proteins and the release of phospholipase C і to establish inositol-3-phosphate and to stimulate the mechanism of calcium reduction by combustion.

3rd type of receptors - histamine receptorH2 ... Гістамін viroblyaєtsya in the shlunks in the center-chromium ogryadnye cells. Gistamin din on the H2 receptor. Here the injection is realized through the adenylate clase mechanism. Adenylate cyclase is activated and cyclic AMP is established

Galmuє is a somatostatin, which can be found in D cells.

Hydrochloric acid- the main factor in the reduction of mucous membranes in the case of a damaged shell. Likuvannya gastritis - suffocation of hydrochloric acid. The antagonism of histamine - cimetidine, ranitidine, blocking the H2 receptor and decreasing the level of hydrochloric acid - is even more widespread.

Suffering water-kaliy ATFazi. Bulo otrimano river, yaka є pharmacological drug omeprazole. Wine brings water-caly to ATPase. Tse duzhe m'yake diyu, reduce the amount of hydrochloric acid.

Mechanisms for regulating slunk secretion.

The process of shlunk etching is cleverly added to 3 and one to one phases

  1. Foldable reflexive - mozkova
  2. shlunkova
  3. kishkova

Inodi 2 remain in the neurohumor.

Foldable reflex phase... Surrounded by the destructions of creeping valleys with a complex of insane and intellectual reflexes, tied together with the reception of the forest. Mind reflexes are detected in case of subtle scent, healthy, auditory receptors, on the sight, smell, on the situation. Tse cleared signals. They will be superimposed on the pouring of podraznikiv onto the empty company, the pharyngeal receptor, the stravohode. Tse crazy razdratuvannya. The same phase of Pavlov and vivchav in the end of the imaginary year. Latent period from the ear of the year is 5-10 quills, so that the slurry starts to turn on. Pislya pripinennya godovannya - secretion is trivial for 1.5-2 years, as long as you do not eat it in the slunker.

The secretory nerves will be bloody. It is through them itself that the inflow is pumped onto the cladding cells, which are used to circulate hydrochloric acid.

bloody nerve stimulation of gastric cells in the antral appearance and acceptance of gastrin, and D cells, de-viroblyayutsya somatostatin to galvanize. Bulo was revealed, on the gastric cell vagus through the mediator - Bombesin. Tse zbuzhuh gastrinovogo klitini. On D cells, for the production of somatostatin wine is brought. In the first phase of shlunkovaya secretion - 30% shlunkovaya juice. Win Volodya with a high acidity, over-etching strength. Meta pershoi fazi - gotuvati shlunok to priyomu uzhi. If you have consumed the shlunkovaya phase of the secretion. When you have a lot of food instead of mechanically stretching the slurry walls, you get sensitive ends of blinking nerves, as well as sensitive ends, which are confirmed by the clines of pid-muffin gossip. At the slunk, there are micese reflex arcs. Doggel's cell (sensitive) sets up a receptor in the mucous membrane and when it is stimulated, it is generated and transmitted to the cell of the 1st type - secretory or motor. Winikє local muscle reflex and zalosa startє pratsyuvati. Clitini of the 1st type і і post-ganglionaramі for the blucous nerve. Bloody nerves trim under control of humoral mechanism. Immediately, with a nervous mechanism, a practical humoral mechanism is started.

humoral mechanism dressings from the vision of Gastrin G cells. The stench vibrates 2 forms of gastrin - from 17 amino acid surpluses - "maliy" gastrin and another form of 34 amino acid surpluses - great gastrin. Maliy Gastrin Volodya is more powerful than the Great Gastrin in the blood. Gastrin, which can be used to prepare cells and food on cladding cells, stimulating the adoption of HСl. Win the same day and on the cladding rooms.

The function of gastrin is stimulating the secretion of hydrochloric acid, stimulating the fermentation of the enzyme, stimulating the motility of the slunk, which is necessary for the growth of the mucous membrane of the slunk. Also, I stimulate the vision of the juice of the slurry. Vibrating gastrin is stimulated not only by nervous factors, but also by food products, which are approved for the hour of splitting and also by stimulants. Before them, the products of the breakdown of wine, alcohol, cava - coffee and non-coffee are introduced. Vibrate hydrochloric acid and lay it in ph at a lower ph lower than 2x, asphyxia virovaniya hydrochloric acid. Tobto tse is tied with this, that is, the concentration of hydrochloric acid and galmu viroblenya gastrin. At the same hour, the end of the concentration of hydrochloric acid and the activation of somatostatin viroblast, and the vitriolation of gastrin. Amino acids and peptides can be consumed without a middle day on the lining cells and produce the secretion of hydrochloric acid. Bilky, volodyucha with buffer powers, tie a proton to water and to provide the optimal level of acidity

Shlunkovu secretion pіdtrimє intestinal phase... If the chyme reaches 12 pounds, then the wine is poured into the shlunkovaya secretion. 20% of the shlunk juice is circulated in the qi phase. At nіy enterogastrіn are viroblyayutsya. Enterooxintin - the hormones are circulated before the HCl, when the slurry goes into the duodenum, before the amino acids are injected. If the acidity of the middle in the duodenum will be temporal, then there is a suppression of stimulating hormones, and enterogastron is violated. One of the species in the future is GIP - gastrointestinal peptide. Wine galmonic acid and gastrin. Bulbogastron, serotonin and neurotensin can also be added to galleys. On the side of the 12 palate intestine, there can be winy and reflexive injections, which stimulate the bloating nerve and turn on the muscular nerves of gossip. In general, the view of the shlunk juice will be deposited as a quantity of yakosti. The amount of slurry sap should be kept at the hour of the transfer. In parallel with the growth of juice, the acidity increases.

The digesting power of the juice is greater in the first year. For the assessment, the juice of the proponation was overtrained Ment's method... Fatty їzha drives shlunk secretion, so it is not recommended to take fatty їzhі on the cob. Nicholas do not give children rib fat until the cob is eaten. Acceptance of fat in front of it - reduces the amount of alcohol that is soaked in the slunk.

Meat is a white product, hlib is a rosin and milk - zmishany.

for meat- to see the maximum amount of juice with the maximum secrecy for another year. With the maximum acidity, it is not enzymatic. Shvidke growth of secretion is surrounded by strong reflex teasers - a sight, a smell. Then, for the maximum secretion, the decrease is reduced, the decrease in the secretion of everything. A high amount of hydrochloric acid and will prevent denaturation of the bottle. Residual cleavage is found in the intestines.

Secretion for hlib... The maximum is to reach the first year. Shvidke nastostannya is tied with a strong reflex teaser. Having reached the maximum of the secretion to reach the shvidko fall, there are few humoral stimulants, ale secretion is trivial (up to 10 years). Enzymatic health - visoka - acidity is mute.

Milk is the main source of secretion... Weakly subtle receptors. Revenge of fat, secretion of galmyt. Another phase, when the maximum is reached, is characterized by a steady decline. Here, fat breakdown products are established, which stimulate secretion. Enzymatic activity is non-viscous. It is necessary to live vegetables, juices and mineral water.

Secretory function of pidshlunkovoy zalozi.

The chyme, which comes in the 12th of the intestine, is fed to the slurry juice, gut and intestinal juice.

Pidshlunkova zalosa- the best value. I have a subordinate function - intrasecretory - insulin and glucagon and general secretory function, which will prevent the circulation of pancreatic juice.

Pidshlunkovoy sіk establish itself in the zalose, in the acinus. Yak visteleni perehidnymi cells in 1 row. Cich cells have an active process of setting up enzymes. They have a good endoplasmic border, Aparat Goldzhi and from the acinus repair the ducts of the subshlung zone and set up 2 ducts, which can be found in the 12 intestine. The smallest duct - Wirsung duct... It is seen in place with the gum duct in the area of ​​the Vater's nipple. Sphinkter Oddi is located here. Another dodatkovy duct - Santorini ascend proximal to the Versungian duct. Vivchennya - an overlay of f_stul on 1 channel. In humans, it is not possible to get implanted by the probe method.

In his own way warehouse for slurry- a glimpse of a barnless line of reaction. The quantity is 1-1.5 liters for extra water, ph 7.8-8.4. The same storehouse of calories and sodium is the same in plasma, a little more than ionic bicarbonate, and Cl less. In the case of acinus, it is also possible to create juice along the ducts in the world before the cells of the ducts will not be tanned in chlorine and some in bicarbonate will be consumed. Enzyme storage

Proteolytic enzymes, which are used for bins - endopeptidase and exopeptidase. The difference is that endopeptidases work on the internal link, and exopeptidases split off endopeptidase amino acids.

Endopepidazi- trypsin, chymotpsin, elastase

Ectopeptidazi- carboxypeptidase and aminopeptidase

Proteolytic enzymes are circulated in an inactive form - a ferment. Activation of vidbuvatsya before the enterokinase. Vona active trypsin. Trypsin is seen in the form of trypsinogen. And the active form is trypsin active іnshі. Enterokinase is an enzyme of intestinal juice. In case of blockages of the duct, it is possible to activate the activation of enzymes in the middle of it with alcohol implantation. To fix the process of self-digestion of pidshlunkovoy zalozi - gostry pancreatitis.

on carbohydrate diet of aminolytic enzymes -alphaamylase, breaks down polysaachridi, starch, glucogen, cannot break down cellulose, from solutions of maltose, maltothiose, and dextrin.

fat litholytic enzymes - lipase, phospholipase A2, cholesterol. Lipase for neutral fats and breaks down to fatty acids for glucerin, cholisterinesterase for cholesterol, and phospholipase for phospholipid.

fermentation on nucleic acids- ribonuclease, deoxyribonuclease.

Regulation of slurry filling and secretion.

Vona is tied to the nervous and humoral mechanisms of regulation and the inclusion of the slurry in 3 phases

  1. smoothly reflexive
  2. shlunkovu
  3. gut

Secretory nerve - bloody nerve, Yakiy dіє on fermentation of enzymes in cells of acini and on a cell of ducts. The infusion of pretty nerves on the pidshlunkovu is not, albeit pretty nerves, the blood flow decreases, and the secretion changes.

Great value of maє humoral regulation pidshlunkovoy zalozi - education of 2 hormones of the mucous membrane. In mucous membranes єC cells, which vibrate the hormone secretin and the secretin gets wet at the roof of the wine on the cellin the duct of the pidshlunkovaya zalozi. Stimulates cellini for hydrochloric acid

2nd hormone is violated by I cells - cholecystokinin... In the development of a secretin on the acidic acid cells, the amount of juice will be less, a little bit more with enzymes and the production of type I cells from the diet of amino acids and in the smaller world of hydrochloric acid. Інші hormones are working on a podshlunkovy zalozu - VIP - nadaє dіyu, I go with secretin. Gastrin is similar to cholecystokinin. In the complex reflex phase, the secretion is seen 20% of the sludge, 5-10% of the attack on the shlunkovaya, and the sieve in the intestinal phase, and the slurry zloza is on the offensive stage, inflowing the shlunkovaya juice, the vyroblenya of the shlunkovaya juice is still firmly connected. When gastritis develops, then pancreatitis follows.

Grass rіdina, as I take an active part in the process of over-etching їzhі, I will call it shlunkoviy sіk. Win revenge on special components, so that you can use split products and get wet brown words. Vyroblennya juice zd_ysnyuєtsya mucous membrane of the slunk. A sufficient amount of grass roots will ensure the normal process of processing was needed. Due to the inflow of negative factors in the acidity of the slunk juice, it can move or decrease, provoking the development of sickness.

Main warehouses of herbal origin

Shlunkovy sik does not smell and color. Win revenge on the mass of components, without any ill-sore etching process. Until the їkh date, carry out:

  • hydrochloric acid;
  • biocarbonate;
  • pepsin і pepsinogen;
  • mucus;
  • internal Castle factor.

Wetness of hydrochloric acid and work with slurry loops. Component є head stock sludge juice. Winning for the level of acidity and for penetrating into the organism of ailing agents. Hydrochloric acid takes an active part in the preparation of the food before the process of over-etching.

Bicarbonate regulates the neutralization of hydrochloric acid. Viroblyayutsya surface mucoid cells. Pepsin and pepsinogen are special enzymes that take part in the process of breaking down the protein. The clearness of the decile forms of the components will preserve the quick rework of the bricks, be it foldable. Fermentation of enzymes is produced by clitines of fundal salmon.

The mucus of the prey the shell of the slunker is injected with various factors, including hydrochloric acid. It is a gel-like ridge, the thickness of the thickness of the shlunka walls is 0.6 mm. Yogo basis is biocarbonati.

The internal Kastl factor is a special type of enzyme, which is an inactive form of vitamin B12. Viroblyaєtsya parental cells of the fundal zaloz.

Chemistry warehouse for sludge juice performances:

  • water,
  • chlorides,
  • sulfates,
  • phosphates,
  • hydrocarbonates,
  • natrієm,
  • kalієm,
  • calcim,
  • amiakom.

Schodnya organizm of people viroblyaє 2 liters of slunk juice. In choloviks, the rate of purging of herbal age becomes 22-29 mmol / year, in females - 16-21 mmol / year.

The change to the smell of slunk juice on foulness is caused by the development of the ignition process in the intestine. The snake of a witch is seen on a red or brown - a vestige of bleeding. Zeleniy abo zhovtuvatiy kolіr talk about houses zhovchі.

Secretion of shlunk juice

The slunk is characterized by a sour middle. The normal level of acidity is reached for a mixture of some hydrochloric acid in the slurry juice. In an undiluted viglyad, there will be no liquidation of ailing bacteria. At rankovy years, up to їzhі, the amount of shlunk juice is insignificant. The component is actively rotated to be repaired in the process of receiving and processing. In the norm, the acidity of the herbaceous line is not to blame for the change of 1.5-2.5 pH.

The secretion of the slunk is basal and stimulated. Basal acidity depends on hydrochloric acid in the shlunk juice in the past. The secretion is stimulated - the price of hydrochloric acid in the slurry for the intake of the liquid. Basically, the basal acidity is significantly stimulated.

The main reason for the decrease in acidity of shlunk juice is the development of gastritis, unbalanced eating, jagged teeth and improper use of bile. Taste of a reduced indicator є the destruction of the process of over-etching and a high risk of development of oncology.

Adjusted secretion is a legacy of improper eating. Prior to provocative officials, they must admit a shrewd reception of alcohol, malignant alcoholic products and uncontrolled use of medications. The main provocateur of acidity adjustment appears to have penetrated into the organism of the bacterium Helicobacter pylori.

Wrong food, especially the implantation of food and fatty food, provoking the use of hydrochloric acid. To bring to the negative inheritance of the post-life period, for the great interruptions between the priyoms of the їzhі. Pogane peresovuvannya in the process of shydogo poglinannya їzhі pіdvischu navantazhennya on the shlunkovo-intestinal tract. The slunk of the snarls is to overwhelm the great shmatka of the yizhi, which is the vimagah chimalikh vitrat of the slunk juice.

trivialy priyom drugs nada negative inflow on the slime casing of the slunk. As a result, there is an overwhelming secretion of shlunk juice. Non-safe drugs - aspirin, paracetamol, analgin and hormonal drugs.

Regular stressful situations to control their additions in the process of overwhelming hydrochloric acid solution. Tyutyunovy dimі alcohol is also unpleasantly poured onto the mucous membrane of the slunker, especially on the heart.

Helicobacter pylori is a provocateur for the development of gastritis and virazki. The bacterium is negatively infused into the slime shell of the slurry, in addition to which the hypersecretion of hydrochloric acid is promoted.

Ailments with a decrease in acidity

The secretion of slurry juice is highly variable due to the influx of negative factors. In most cases, it is normal to provoke sickness in the intestinal tract. The main changes before the development of pathologies, tied with a decrease in secrecy, є:

  • gastroduodenitis;
  • gastritis due to low acidity;
  • shlunk cancer.

All pathologies may be similar to the symptomatology; Only if you can correctly diagnose the type of illness.

gastroduodenitis

tse pathology fiery character I will hunt for the mucus shell of the slunker and two-fingered intestine. є shape chronic gastritis, Inspiration of what kind of zapalnja zachіpaє susіdnі organi. To develop with genetic schlichnosti, ominous evil and alcoholic products. Provoke gastroduodenitis of healthy parts of stress and penetration into the organism of Helicobacter pylori bacteria. To get sick, characterize nudota, pain syndrome in the area of ​​shlunka, cutting, oven and breakage of style.

Gastritis with low acidity

Zakvoryuvannya є by the ignition process of the mucous membrane to the organ. The yogo belt is pummeled with a decrease in the acidity of the slunk juice. Pathology develops due to the infusion of Helicobacter pylori bacteria, igniting diseases of the herbal system, endocrine and autoimmune diseases. supervise dumb sickі vagoya in the epicheral dіlyantsі. Patients get up to school with abdominal pain, diarrhea and gurgling in the intestines. Dodatkovy symptoms є anxiety, boredom and an inappropriate daze in the mouth. It is not possible to show a "zayda" in the coils of the rota and the ignition process on the mucous membrane of the mouthwash.

Crawfish cancer

views evil new ideas, Scho was diagnosed with the blood of the mucous membrane to the organ. Before the influx of negative factors in the health of the cells, they repair their regeneration. Provokuvati oncology zdatne wrong eating, malignant alcohol and the manifestation of illness of the shlunkovo-intestinal tract.

on early stages the cancer of the shlunk does not manifest itself. In the world, there is a wider pathology of bile in the shlunk, zagalny weakness, unprimed vagina, boring and bloating. People have a low rate of patronage, a level of hemoglobin in the blood of a fall.

Ingestion at acidity alterations

Before the most widespread ailments are:

  • gastritis with acidity;
  • vyrazkovі urazhennya shlunnya;
  • functional dyspepsia.

The development of pathological processes is accompanied by an influx of negative factors.

Gastritis with acidity

With this type of ailment, hydrochloric acid is seen in the superficial mixture. The whole process is spontaneous in case of improper handling, tyutyunopalinnya, trivial reception of drugs and robots on a shrewd virobability. Systematic stressful situations can also take overworldly secretion of hydrochloric acid. The development of gastritis with an increase in the acidity of shlunk juice is possible with an infectious impaired organism, impaired communication processes and an impaired endocrine system.

Signs of ailments with an excess and shortage of grubbing of grubs are practically not recognized. Lyudina is experiencing discomfort in the area of ​​the slunker, and she is getting more and more important. In the world of progressing pathology, there are stoves, hairstyles, boring and unacceptable attention in roti. Bloating is not included.

Virazki and virazkov_ battle

The twists and turns are distinguished by the high acidity of the herbaceous origin. Systematic injection of hydrochloric acid is carried out into the slurry prior to ignition processes. At the outset of therapy, trophic damage is detected from the further statements of the disease. The cause of the pathological process є stressful situations, fired up organs in the intestinal tract and damage in the robot.

Virazkovі damage to the body is not often є the inheritance of such pathologies, such as tuberculosis, pancreatitis, cirrhosis of the liver and hepatitis. On the appearance of a curve in the case often at the upper part of the abdomen. The world is growing ill and the intensity of growth.

Strengthening the pain to fiksuєtsya during trivial interruptions between the priyomas of the їzhі. Patient skarzhitsya for a strong oven and boring. Vinnik's blues after 30-120 chilines sent to the reception of їzhі.

The rate of rapid therapy in case of infection of the development of slunk bleeding.

Functional dyspepsia is associated with pain or discomfort in the epicranial dyspepsia. At the same time, there is an emergence in the robotic slunk-intestinal tract in the direction of the day. Dyspepsia develops in the presence of psycho-traumatized and stressful situations... Patient preschool nudota.

The value of the acidity level of the slurry juice is helpful for specialization laboratory dosage... Stink in the minds medical mortgage... Increasing the acidity level of the shlunkovy line allows to eliminate the problem of the shlunkovo-intestinal tract and prevent the deterioration of the etching process.