Dengue lover. Dengue is a feverish woman. Laboratory methods for follow-up

• Sho take Likhomanka Dengue
• Dengue Dickhead Symptoms
• Diagnostics of Garyachki Dengue
• Likuvannya Garyachki Denge
• Prevention of Lichomaniac Dengue
• Until then, you have to kill Likhomanka Denge.

Sho take Likhomanka Dengue

Zahvoryuvannya vіdomo finish for a long time. According to the main symptom complex, the ailment was called bone crusher fever. The concept of dengue haemorrhagic fever was established only in 1954 when it was described classic paintings feverishness among children in the Philippines, and also in the other regions of the Great Northern Asia. Until the end of the day, you will be able to prove the viral etiology of the ailment.

Shou provokuє Lichomaniac Dengue

Dengue pathogens are classified as viruses of the Togaviridae family in the genus Flavivirus (arbovirus antigenic group B). RNA is removed, two-ball lipid shell is removed from phospholipids and cholesterol, the size of the virus is 40-45 nm in diameter. It is activated during the treatment with proteolytic enzymes and when the food is programmed at 60 ° C, with an infusion of ultraviolet analysis. There are 4 types of dengue viruses that are antigenic. Viruses dengue may cause an antigenic dispute with viruses of the female fever, the Japanese and Western Nil's encephalitis. Reproduce on tissue cultures and cells nirok mavp, hom'yakiv, KB and in. In the blood of sick people, the viruses become infected at room temperatures up to 2 m / s, and hanging - up to 5 years.

For the last 10-15 years, there is more to the growth of sickness in the rural regions. I have seen about the significant dengue sleepers in the Chinese People's Republic, Vietnam, Indonesia, Thailand and Cuba. For an hour to sleep in Cuba in 1981, a fever dengue suffered more from 350,000 individuals, close to 10,000 of them fell ill with a greater hemorrhagic form, 158 ailments died (mortality 1.6%). In the Chinese People's Republic, 437,468 people fell ill in 1980 (54 died). The hour of the epidic sleeper 1985-1986 rr. fell ill 113 589 individuals (died 289). The reasons for the disease to become obscure, unimportant to the great interest to the problem of dengue fever (for the period 1983-1988, 777 robots were published in the periodical press, in addition, the dengue problem was looked at in 136 books).

dzherelom іnfektsії to serve the sickness of lyudin, mavpi i, mozhlvo, kazani.

Transmission of infection in humans is transmitted by Aedes aegypti mosquitoes, in mawp - A. albopictus. The A. aegypti mosquito becomes infectious in 8-12 days after feeding the sick people with the blood. The mosquito will be reported up to 3 months or more. The building virus grows in the least of a mosquito at a temperature not lower than 22 ° C. At the same time, dengue is widened in tropical and subtropical regions (from 42 ° winter to 40 ° eastern latitude). Dengue is living in the lands of the Great Patriotic and Eastern Asia, Oceania, Africa, the Caribbean Sea basin. It is difficult for children, as well as individuals in the endemic region.

Naturalness of people Visoka, bowls of ill children, and individuals who arrived in the endemic districts. Postinfectious immunity is typical, stable and triple rocky. Repeated illnesses may occur after the end of the hour, for example, if the virus is of a certain type.

Pathogenesis (how to see?)

The virus penetrates into the body through the skin when bitten by humans and becomes infected with a mosquito. At the point of infection, in 3-5 days the virus is interrupted, and the virus will be multiplied and accumulated. In the last 12 years of the incubation period, the penetration of the virus into the roof is meant. Viresemia is common until the 3-5th day of the hot period. Dengue can be found in classical and hemorrhagic forms. Suvoroi fallowness is not a type of virus and is not a clichéd picture. From the ailments of the so-called phylopian hemorrhagic fever, 5 types of dengue viruses were seen in 2, 3 and 4 types, with Singapore hemorrhagic fever - all 4 types, with the assessment of the new type of dengue fever, the same The appearance of the types of viruses in the virus was not confirmed.

In this hour it was established that dengue hemoragic fever and dengue shock syndrome can be affected by all of the dengue virus serotype. In the pathogenesis of ailment, the role of development in the organism of human viruses of serotypes 1, 3 or 4 is especially important, behind which through a few rocks and serotype 2. In the development of hemorrhagic fever, dengue is especially significant immunological factors... The growth of dengue virus serotype 2 grows in mononuclear phagocytes, taken from the peripheral blood of immunized donors, or in cells of non-immunized donors in the presence of subneutralizing hetotropic concentrations of antioxidants The virus-antibodies complexes adhere, and then they enter the mononuclear monocytes behind the additional Fc receptors. Active replication of a virus in cych cells can lead to a series of secondary reactions (activation of complement, systemic kinin and inn.) And to the development of thrombohemorrhagic syndrome. In such a rank, hemorrhagic forms are determined as a result of repeated infection of muscular dwellers, either in the case of the first infection of new-born women, as they rejected antibodies from the mother. The interval between the first (sensitizing) and repeated (as permissible) infections can occur from 3 months to 5 years. When the first infection is a type of virus, the classic form is dengue. I know that I am in the middle of the endemic middle of the village with only a classic form of dengue.

hemorrhagic form to develop deprived of the inhabitants of the Muscovy. With this form, there is a great deal of other damage, the swelling of the endothelium, the perivascular embryo and the infiltration of mononuclear cells appear. Increase the penetration of sudin to cause damage to plasmas, anoxia tissue, metabolic acidosis. The development of widened hemorrhagic manifestations is tied to the damage of the aggregate body of blood. In more important cases, there are many hemorrhages in the pericardial endotitis, pleura, ocherevin, mucous membrane of the intestine, in the brain.

Virus dengue rob also toxic diyu With yakim tied degenerative worms in peppers, nirkas, myocardiums. pislya postponed affliction Immunity is close to 2 rockiv, the protein is type-specific, it can be repeated in the same season (after 2-3 months) for the infection with this type.

Dengue Dickhead Symptoms

Incubation period three days from 3 to 15 days (more than 5-7 days). Zvvoryuvannya zvvychay repaired rapta. In case of severe ailments in 6-10 hours, there is a sharp turn of prodromal lesions in vigilance and headache. Name the average general health z'yavayutsya chills, pain in the back, creeps, ridges, slopes (especially colony). The feverish woman is susceptible to all ailments, the temperature quickly moves up to 39-40 ° С. for a large number of ailments - hyperemia and thickening of denunciations, in'n'ktsiya sudin's sclera, hyperemia for the sake.

For a critical interruption, they develop a hot form of dengue (classic) and a hemorrhagic dengue fever.

Dengue fever is a classic opposingly, if a person with ailments (less than 1%) may develop a coma due to zupinka dikhannya. at classic feisty dengue is characterized by a dynamic pulse: a spate of accelerations, then from the 2-3rd day bradycardia appears up to 40 beats / min. Significant leukopenia (1.5-10 9 / l) with apparent lympho- and monocytosis, thrombocytopenia is promoted. In most cases, peripheral lymphatic universities grow. The arthralgia swells, but at the myaz and the stiffness the rigidity of the oversaturated ailments. Until the end of 3 days, the temperature of the fire is critically falling. The remission is difficult 1-3 days, as the temperature rises again and the main symptoms of ailments appear. After 2-3 days, the temperature will drop. The triviality of the feverish woman is 2-9 days. The characteristic symptom of dengue is visip. There may be some one hour of the first hot sickness, often at a different temperature, and sometimes in the period of apirexia due to another sickness, on the 6-7th day of the sickness. However, dengue ailments can be defeated without visipu. Visip develops polymorphism. Most often, it is low-papular (bark-like), ale may be petechial, scarlet-like, urticarial. Visip ryasna, sverblyachі, occasionally come to the tulub, then expand to the pictures, pouring peeling for itself. Visipu elements take 3-7 days to last. Hemorrhagic manifestations are susceptible to rare (in 1-2% of ailments). During the period of convalescence, a trivial hour (up to 4-8 years), asthenia, weakness, decreased appetite, sleeplessness, malignancy and swelling pains.

Hemorrhagic fever dengue(Fіlіppіnska haemorrhagic fever, Thai haemorrhagic fever, Singapore haemorrhagic fever) is more important. The ailment can be repaired quickly, the cob period is characterized by temperature changes, cough, anorexia, nausea, bloating, abdominal pain, sometimes even severe. The cob period is trivial 2-4 days. On the basis of the classic form of dengue mialgia, arthralgia and pain in the cysts, there is little evidence of pain. When the temperature is deflated, the temperature is increased to 39-40 ° C and the mucous membrane of the dysplasia and the back of the throat is hyperemic, palpable increase in lymph nodes, liver. At the period of time, the sick person's camp grows shy, the build-up is weakness.

For the assessment of the severity of the process, the WHO proponed Clinical Classification of Hemorrhagic fever dengue... I see 4 steps, which are characterized by such key symptoms.

step I... Lichomaniac, symptoms of intoxication, hemorrhage in the lytic zginia when the cuff is applied abo jgut ("jgut test"), in the blood - thrombocytopenia and thickened blood.

stage II... All manifestations, characteristic for stage I +, are spontaneous bleeding (internal, clear, intestinal), with pre-existing blood - a greater increase in hemoconcentration and thrombocytopenia.

stage III... Div. Stage II + circulatory deficiency, damage. Laboratory: hemoconcentration and thrombocytopenia.

stage IV... Div. Stage III + glib shock ( arterial vise 0). Laboratory - hemoconcentration and thrombocytopenia.

Grades III and IV are characterized by dengue shock syndrome. When ailing ailments during the period, ailments fall apart, it is considered a sick person, when it is cold and sticky, the tulub is warmer. It is evident that there is blistering, cyanosis of the lips, in half of the ailments petechias appear, often localized on the forehead and on the distal discs of the pictures. Ridche z'yavayutsya plyamista or maculopapular visip. The arterial grip decreases, the pulse grip changes, tachycardia, cyanosis of symptoms occur, and pathological reflexes appear. Death often persists on the 4th-5th day of the ailment. Crooked blues, coma or shock є predictively unpleasant signs. Extensions of cyanosis and sudomy are a terminal manifestation of ailments. Ailments, who survived a critical period of ailments (period of ailments), quickly fix their oduzhuvati. No recurrence of ailments. Hemorrhagic fever dengue is often spared in children. The lethality in the form is close to 5%.

accelerating- encephalitis, meningitis, psychosis, polyneuritis, pneumonia, parotitis, otitis media.

Diagnostics of Garyachki Dengue

When it is recognized, it is necessary to take epidemiological changes of mind (transfer to the endemic world, the level of incapacitation and in.). In the period of epіdemic sleep clinical diagnostics not being difficult and priming on the characteristic key developments(Dvokhvilova is a feverish woman, visip, more in myases, more in suglobs, lymphadenopathy).

Diagnosis of dengue haemorrhagic fever is primed on the criteria, broken down by WHO. To them are admitted:
- feverish - gostre cob, visoka, stiyka, trivial from 2 to 7 days;
- Hemorrhagic manifestations, including a positive test of jgut, be it from the onset of criteria: petechia, purpura, ekchimozi, nasal bleeding, bleeding is clear, bluish curve or melena;
- improved stove; thrombocytopenia is not more than 100x109 / l, hemoconcentration, hematocrit is not less than 20%.

Criteria for diagnostics of dengue shock syndrome - fast, weak pulse with changes in pulse pressure (not more than 20 mm Hg. Art.), Hypotension, cold, sticky skin, restless. The classification of the WHO includes the descriptions of the earlier stages of gravity. With the classic dengue fever, there may be a slight swelling of hemorrhagic symptoms, but they do not meet the criteria of the WHO for the diagnosis of dengue hemorrhagic fever. Cysts are seen as a dengue fever with hemorrhagic syndrome, but not as a dengue fever.

Laboratory diagnosis confirms the appearance of a virus from the blood (in the first 2-3 days of ailments), as well as the increase in the titer of antibodies in young men (RSK, RGGA, neutralization reaction).

Differentiation from painter, chikungunya fever, pappatachi, fever fever, other hemorrhagic fever, infectious-toxic shock with bacterial illnesses(Sepsis, meningococcemia and in.).

Likuvannya Garyachki Denge

There are no specific ways of detecting dengue fever dengue. In case of hemorrhagic fever and shock syndrome, corticosteroids and antibiotics are vicious, but efficacy has not been reported. In case of shock syndrome, it is recommended to go in from the front desk water balance organism and storing of plasma.

friendly prognosis with classic and severe with hemorrhagic forms of illness (lethality in case of rest becomes 30-50%).

Prevention of Lichomaniac Dengue

immunization
On the current day of licensed anti-dengue vaccines. The marketing of vaccines against dengue ailments (lungs, and important forms) is complicated in connection with those who can be vicious whether it is because of those who are dengue viruses, because the vaccine is guilty of capturing all types of viruses tetravalent. Prior to that, the appearance of certain types of models and between the reason for the pathology of ailments and the immune reactions, leading to a hindrance, more accelerated the development and general evaluation of the candidate vaccine prototypes. Protest, in the development of vaccines, zdatnyh zhistit from all chotiroh viruses in dengue, reaching progress. Two candidate vaccines are being tested at the stage of clinical assessment in endemic regions, and a number of other candidate vaccines - for more early stages rosettes. The WHO Initiative for the Advancement of Vaccines is aimed at developing and evaluating vaccines against dengue by technical advice and criticality in such areas as, for example, in the field of vaccine immunity in the areas of vaccine selection and testing.

In Denmark, the only way to control any transmission of dengue virus is to control mosquito carriers.

In Asia and America, Aedes aegypti multiplies, as the head rank, in the opened human capacities, such as clay vessels, metal barrels and concrete tanks, which are used for collecting home supplies of water, as well as old products for car plastics. , in which the board water accumulates. In Africa, mosquitoes also proliferate widely in the natural environment - in the hollows of trees and on leaves, like "cups", in which water is drawn.

In the rest of the rock, Aedes albopictus, a carrier of dengue in Asia, is of other importance, having expanded in the New States of America, in the countries of Latin America and the Caribbean, as well as in some parts of Europe in Africa. The geographic broadening of the species has become, in the meaning of the world, as a result of the international trade in old tires, which is the middle of the breeding of mosquitoes.

The fight against infectious carriers is carried out on the basis of rational vicariousness of the midst and the stagnation of chemical methods. It is necessary to dispose of solid inputs and practice the practice of capturing water, including in critical capacities, which provide access to the eggs of female mosquitoes, to be included in the number of methods recommended in the framework of programs on the ground. Victory of proper insecticides in places of purchase of larvae and, especially, in households, for example, in vessels for the collection of water, allowing for the reproduction of mosquitoes in a stretch, it is necessary to repeat it as often as possible. With the success of the vicorisation, there are also some ribs and crustaceans, as they eat mosquitoes.

For an hour, if you have slept through ailments suspiciously, go in to fight against carriers of infection. However, the effectiveness of such visits due to the inferiority of mosquitoes is of a time-consuming nature and lies in the presence of those that have penetrated the aerosol dots in the middle of the primordial, perhaps over-grown individuals. Until then, come in dear and importantly. For the correct selection of chemical words, it is necessary to conduct regular monitoring of the sensitivity of the carriers to widespread insecticides. To ensure the effectiveness of the program, it is necessary to carry out active monitoring and monitoring of the natural populations of mosquitoes by visits to fight against carriers.

Fakhіvtsі of the First Medical University іmenі Pavlov near St. Petersburg, nanoparticles were dissolved in addition to the possibility of diagnostics of infarction and before infarction of a sick person. So, in the future, nanoparticles will be stagnant ...

Medical statistics

Sarcomi: scho tse take i yak

As many as 5% of the more evil chicks store sarcomas. The stench appears to be high aggressiveness, quick expansion of hematogenous path and slenderness before relapses during treatment. Deyaki sarcomas develop in rocks, they do not show themselves to themselves ...

Viruses do not only hang in the weather, but they can eat on the handrails, sit and on the surface, while retaining their activity. To that, in trips, or in huge mіstsyah, bazhano not only wicked together with otchuvannya people, ale and unique ...

Turn a good view and say goodbye to the eyepieces every time contact lenses- the world of bagatokh people. Infection can be done quickly and indefinitely. The new possibilities of laser correction will lead to the emergence of the contactless technique of Femto-LASIK.

Cosmetic preparations, signs of keeping an eye on our skin and hair, for the sake of it may not appear unbaked, as I think

Likhomanka dengue - gostra zooanthroponous arbovirus ailment infection with the transmisive mechanism of transmission of the zest, expanded in the edges of the tropical and subtropical belt.

Epidemiology

Dzherelo of an infectious disease is a disease of lyudin and mavpi, in those who have a disease it can be latent.

In endemic regions, there are natural ailments, in some circulations, viruses are seen among maws, lemurs, bilks, kazans, and, perhaps, others. Carriers - mosquitoes to the genus Aedes(A. aegypti, A. albopictus, A. cutellaris, A. polinesiensis), it is possible, the main role to lay the mosquitoes on the canopy Anophelesі Сіleх.

mosquitoes Aedes After bloodsucking, they become infectious in 8-12 days in fallowness from temperature minds. It’s possible to get infected by a stretch of life, that is 1-3 months, protects at temperatures below 22 ° C.

The infection of people in the endemic regions has called for the formation of strong anthropurgical infections in the form of infections, all from the natural minds. In cichs, the middle dzherelo zbudnik - lyudin's ailment, which can become infectious for adding ailments to the cob and become infectious after the first 3-5 days of ailments.

The main carrier of the wild plant in the human population is the mosquito A. aeguti, what a bagє in the life of the people. The female mosquito bites a lyudin during the day. The mosquito is most active at temperatures of 25-28 ° C, at the same temperature the number reaches the maximum, and the term of infectiousness for bloodsucking is minimal. Lyudina visokosprimchiv to dengue fever. an infected person is seen with a single mosquito bite. In people of skin from chotir'h types, the virus has a classic form of dengue fever and dengue fever. The immunity of the transferred ailment is short-lived, three-fold of rocky, type-specific, that is, if the transferred ailment of a human being is lost, it becomes susceptible to the virus serotypes. Great Epidemias are linked to the introduced type of virus, which is not in control of the given region, but in the region (Krajina), it is generally endemic. The classic dengue fever and the hemoragic dengue fever dengue grows quite rapidly. Classical dengue spares the middle of the inhabitants of the world, especially children and those who live in it, and the hemorrhagic fever Dengue is a major child. Peaks of sickness fall on two groups: up to 1 rock, as passive immunity against the virus of the other type, and children of the 3-ric type, as overturned classic dengue. In the first group, the immune system is formed according to the type of the primary, in the other - according to the type of the secondary. Hemorrhagic fever Dengue in severe form - dengue shock syndrome most often develops when infected with another type of virus in children who are infected, as they were transferred to the last dengue, viclican with viruses I, III and IV type. So, before the hour of the epidemic in Cuba in 1981, a bullet was established, but in 98% of the ailments there was an important breakdown of the ailment and shock dengue bully syndrome associated with type II virus infections with the presence of antibodies to type I virus.

Dengue fever reasons

The reason for the dengue fever is arbovirus, which is known to the genus Flavivirus, families Feaviviridae. The genome of single-stranded RNA representations. The size of the virion is 40-45 nm. Madodatkovu supercapsid membrane, which is tied with antigenic and hemagglutinating powers. Style in the midst of middling low temperatures(-70 ° C) and in a dried cure: sensitive to formal and ether, inactivated during treatment with proteolytic enzymes and when heated to 60 ° С. DEN I, DEN II, DEN III, DEN IV. Dengue virus is transmitted to people through the bite of mosquitoes and to be included in the ecological group of arboviruses. There has not been established a rotational fallowness of the clinical picture of the virus serotype. Virus is weak in cytopathic activity. Yogo replication is seen in the cytoplasm of blood cells. Mavp has no symptoms of infection with a form of immune disease. Viruses pathogenic for neonatal big targets when infected in the brain or intracranially. Virus proliferates in tissue cultures of nirok mavp, khom'yachkiv, yachok mavp, as well as on the lines of cells HeLa, KB and shkiri people.

pathogenesis

Infection is caused by the bite of an infected mosquito. The primary replication of the virus is seen in regional lymph universities and clinics of the Sudin endotelia. In the end of the incubation period, a virus develops, which supervises the development of a fever and intoxication. As a result, different organizations and textiles are improved. It is with the organisms that I shall tie the re-tying of the feverish woman. Oduzhannya is tied to the accumulation in the blood of complement-sounding and virus-neutralizing antibodies, which are stored in a stretch of decaying rock.

A similar pattern of pathogenesis is characteristic of classic dengue, which develops when there is an active abnormal immunity.

Dengue fever symptoms

Symptoms of a dengue fever may be absent or there is a contraction of an undifferentiated dengue fever, a dengue fever or a Dengue femoral fever.

Clinically in the fall Incubation period fever dengue triva from 3 to 15 days, often 5-8 days. I develop a classic, atypical haemorrhagic fever Dengue (without dengue shock syndrome and supervise it).

The dengue fever is a common fever to repair from a short-hour prodromal period. For an hour now, it means nezduzhannya, conjunctivitis and rhinitis. However, the prodromal period is more often than not. Symptoms of a dengue fever can be repaired with a chill, a sharp temperature increase up to 38-41 C, which can last for 3-4 days (cob period of ailment). It hurts to scream for strength head b_l, More in very apples, Especially with rus, m'yaz, great slopes, ridges, lower kintsivkakh... Tse to make it difficult when it comes to Russia, the paralysis of the sick (the name of the ailment resembles the English "dandy" - medical burden). With a severe interruption of ailments, an order with a strong headache may cause blues, madder, loss of svidomost. Sleep collapses, appetite goes down, in mouth there is a girkot, weakness and outwardness are abruptly rotated.

Already from the first day, ailments change zovnishniy viglyad ailing: exposing yaskravo hyperemyovane, swirling in 'uktsia sudin sclera, hyperemia of the conjunctivi. Often on the soft sky there is an enanthem. Mova of deposits. Look through the fear of God. By the way, there is an improvement in the cookies, however, they do not support them. Characterized by a decrease in peripheral lymphatic universities... Until the end of 3 dib, or by 4 dib, the temperature will critically drop to normal. The period of apirexіі is trivial to grow 1-3 days, then the temperature rises up to higher digits. In people with ailments of the period apirexii, they do not sposter ailments. A characteristic symptom is visip. Visip will appear on the 5-6th day of ailments, one earlier, a sprinkle on the breast cancer, internal surface shoulders, then widen to the tulub and kintzivki. Plyamisto-papulogenous viscous is characteristic, the yak is often superfluous to sverbinnyi, overflowing with peeling.

Zagalnaya triviality of a feverish woman - 5-9 days. In the hemogram in the cob period - an internal leukocytosis and neutrophilosis. пізніше - leukopenia, lymphocytosis. Proteinuria is possible.

With atypical fever, dengue sposter fever, anorexia. headache, mialgia, ephemeral visip, polyadenopathy during the day. The triviality of ailments does not change 3 dB.

Hemorrhagic fever Dengue has types of symptoms, with 4 main symptoms: temporal fever, hemorrhage, hepatomegaly and lack of blood circulation.

Hemorrhagic fever dengue to recover from a rapid increase in temperature up to 39-40 C, severe chills, headache, cough, pharyngitis. On the basis of classic dengue music and arthralgia are spontaneous. At important vipadkah quickly develop prostration. Characterized by the swelling and puffiness of the individual, the glare of the eyes, the hyperemia of all visible shells. It is not uncommon to mean Scarlet-like background of all body, on the smallest point there is a visip, mainly on the original surfaces of light and colony slopes. At the beginning of 3-5 days, ailments appear bark-like plyamisto-papulogenous or scarlet-like visip on tulubs, and later - on tips and faces. It means pain in an epigastric period, or in all belly, which is superfluous. Pochinka bolucha, zbіlšena.

After 2-7 days, the temperature often drops to normal or low rivnya, the symptoms of dengue fever may regress, infusion. In case of a serious interruption, the patient's camp will go down. The most frequent hemorrhagic sign is positive test with dzhgut (for most ailments, sints are found in misciah in''ktsiy). Petechia appear on the school, children of blood, Bleeding. There is a significant decrease in the number of thrombocytes, the indicator of hematocrit increases by 20% or more. The development of hypovolemic shock is characteristic.

stages

In important cases of writing decile days high temperature the camp of the ailing rapt pogirshutsya. When the temperature drops (between the 3rd and the 7th day of ailment), there are signs of impaired blood circulation: the skin is cold, swollen, covered with beaches, it often means cyanosis of the skin around the mouth and the heart rate is more frequent.

The pulse of parts, ailments restless, skarzhitsya on a beat in the stomach. Deyakіkіvorі zalmovanі, protest, they develop zabudzhennya, for whom the stage of shock is critical. The camp is progressively degraded. In the area of ​​chola and distal kintzivok there is a petechial visip, an arterial grip decreases sharply, its amplitude changes, the pulse is thread-like, tachycardia and backlash will be accepted. Shkira is cold, vologa, growth of cyanosis. On the 5-6th day, vinikє is crooked bluvota, melena, sudomi. The triviality of shock is not great. The sickness can die in 12-24 years, or I am very quick when I come in. Oduzhannya with hemoragic fever Dengue with shock or without shock infusion quickly and without delay. A friendly prognostic sign - renewal of appetite.

With pre-adult blood, thrombocytopenia, high hematocrit, increased prothrombin (in one third of patients) and thromboplastin hour (in half of the sick), hemophilic blood production, degeneration in metabolic acidosis... In a large number of cases, it means hemoconcentration (to indicate the loss of plasmas), and in ailments without shock. The number of leukocytes varies from leukopenia to low leukocytosis. Lymphocytosis often occurs with atypical lymphocytes.

Deyakі ailments sposterіgaut such symptoms of dengue fever, as a lesion of the central nervous system, and itself: sudom, spasms і trivial (at 8 o'clock) loss of svidomostі.

The dengue fever can be accelerated by shock, pneumonia, encephalitis, meningitis, psychosis, polyneuritis.

form

razr_znyayut dvі key forms ailments: classic and hemorrhagic (dengue shock syndrome).

A common dengue fever (synonymy - dengue, bone-crushing fever) is characterized by a two-horned fever, pain in the slopes, pain in myaz, visip. polyadenitis, leukopenia and good interruption of ailments.

Hemorrhagic fever dengue ( ferbis hemorragka dengue, synonym - dengue shock syndrome) is characterized by the development of thrombohemorrhagic syndrome, shock and high lethality.

Diagnosis of dengue fever

Diagnosis of dengue fever according to the criteria of the WHO is carried out at the time of the onset of symptoms:

• temperature adjustment up to 39-40 ° С, which takes 2-7 days;
• showing signs of thrombohemorrhagic syndrome (petechia, purpura, hemorrhage, bleeding):
• improvement of ovens;
• thrombocytopenia (less than 100x10 9 / l), increased hematocrit by 20% or more;
• development of shoku.

The first two clinical criteria in admitted are thrombocytopenia and hemoconcentration abo we will advise the hematocrit is sufficient for the diagnosis of Dengue's hemorrhagic fever.

It is also necessary to have an epidemiological history (transfer to an endemic history).

Diagnosis of dengue fever (classic form) characteristic symptoms: Bil in slopes and meats, fever fever, visip, lymphadenopathy, periorbital and head bile.

In case of classic dengue fever, there may be a slight swelling of a hemorrhagic disease, which does not meet the criteria of the WHO. In cich vipadkah diagnose dengue fever with hemorrhagic syndrome, but not dengue fever.

Diagnosis of dengue fever serological dosages... There are two main methods for diagnosing dengue fever: seeing the virus and detecting an increase in the titer of antibodies to the dengue virus (in young people in blood in RSK, RGGA, RN-viruses). Seeing a virus gives accurate results, but for a person who is of a genus, a laboratory is required specially. Serological tests are much simpler, and they will be delivered in less than an hour. However, there are possible cross-reactions with other viruses. This can be the reason for the positive results.