Dopamin is shown until the end of the day. Dofamin - Ferein - official instructions and costs. How to save and add.

Dopamine and adrenergic drug

Form vipusku, warehouse and packaging

Additional speeches: sodium disulfite - 1 mg, hydrochloric acid 0.1m to pH 3.5-5.0, water d / i - up to 1 ml.












Additional speeches: sodium disulfite - 2 mg, hydrochloric acid 0.1m to pH 3.5-5.0, water d / i - up to 1 ml.

  • Addition of glucose levels in the blood of Diabetics in sick people.
  • Decreased leukocyte.
  • Thrombocyte reduction.
  • Transaminase transition.
  • Dry mouth Nudota Bluvota Diarrhea Constipation.
Read all of the brochures, first and foremost before starting the ceremony.

Natural hormone dopamine and antagonism

Even if some of the side effects become serious, if you remember if you didn’t have any side effects, if you didn’t get it on the whole list, you’ll look at your doctor or the pharmacist for all the recipes and without a prescription / herbal products. likarev or a pharmacist. As soon as you have a power supply, be sure to turn up to a doctor or a pharmacist. ... This drug is recommended in the offensive.

5 ml - ampoules (5) - packs of middle contour (1) - packs of cardboard.
5 ml - ampoules (5) - packs of middle contour (2) - packs of cardboard.
5 ml - ampoules (5) - packages of middle contour plastics (1) - packs of cardboard.
5 ml - ampoules (5) - packs of middle contour plastics (2) - packs of cardboard.
5 ml - ampoules (5) - packaging of middle contour (50) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packaging of middle contour (100) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packaging of middle contour plastics (50) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packaging of middle contour plastics (100) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packs of cardboard.
5 ml - ampoules (10) - packs of cardboard.
5 ml - ampoules (250) - cardboard boxes (for stationary).
5 ml - ampoules (500) - cardboard boxes (for stationary).

List of information required before receiving

Low flow syndrome includes in itself. For heart surgery, shock for carrying infectious diseases, for epidural anesthesia and spinal cord. Mechanic reversal code for alarming a wikidus of a lactic acid, especially obstructive cardiomyopathy, aortic valve, allergy to dopamine. Cycles, as a rule, are not recommended in the context of association with anesthetic agents, antidepressants, guanethidine, and we will tie them to them.

Rules for victorious items, special measures

Accelerated atrioventricular conductivity: it can lead to increased activity of slugs in ailments from fibrillation or trifling of ectopic activity, dopamine to the possibility of accepting or provoking slugs Serious breakdown of the rhythm: the patients with such a history will be especially controlled from the uninterrupted recording of the EKG. tsey lykarskiy zasib Revenge 17, 5 mg of calories in 5 ml.

Additional speeches: sodium disulfite - 2.5 mg, hydrochloric acid 0.1m to pH 3.5-5.0, water d / i - up to 1 ml.

5 ml - ampoules (5) - packs of middle contour (1) - packs of cardboard.
5 ml - ampoules (5) - packs of middle contour (2) - packs of cardboard.
5 ml - ampoules (5) - packages of middle contour plastics (1) - packs of cardboard.
5 ml - ampoules (5) - packs of middle contour plastics (2) - packs of cardboard.
5 ml - ampoules (5) - packaging of middle contour (50) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packaging of middle contour (100) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packaging of middle contour plastics (50) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packaging of middle contour plastics (100) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packs of cardboard.
5 ml - ampoules (10) - packs of cardboard.
5 ml - ampoules (250) - cardboard boxes (for stationary).
5 ml - ampoules (500) - cardboard boxes (for stationary).

Vzaєmodia with іnshy lіkarskiy zasob

See your doctor, since you have nirkova lack... Until "the ear of a taste for dopamine, docilely, you can correct it, you can fix it with a shlyah, and also" you can get acidosis, either of hypoxia, or offending, as well as "a lot of hypoxia". for the victorious lіkіv.

Vzaєmodiya with products kharchuvannya and vodka

Interaction with likarskiye zasob or alternative methods of lіkuvannya

Vikoristannya pid hour of visit thoracic treatment... Dopamine may be punished for an hour of vaginosti, if it is necessary. Consult your doctor or pharmacist, first of all, take any drugs.

List of information required before receiving

Low flow syndrome includes in itself. For heart surgery, shock for carrying infectious diseases, for epidural anesthesia and spinal cord. Mechanic reversal code for alarming a wikidus of a lactic acid, especially obstructive cardiomyopathy, aortic valve, allergy to dopamine. Cycles, as a rule, are not recommended in the context of association with anesthetic agents, antidepressants, guanethidine, and we will tie them to them.

Rules for victorious items, special measures

Accelerated atrioventricular conductivity: it can lead to increased activity of slugs in ailments from fibrillation or trifling of ectopic activity, dopamine to the possibility of accepting or provoking slugs Serious breakdown of the rhythm: the patients with such a history will be especially controlled from the uninterrupted recording of the EKG. Cei lykarsky drug revenge 17, 5 mg of calories in 5 ml of the size taken until the respect in the normal ratio.

Additional speeches: sodium disulfite - 5 mg, hydrochloric acid 0.1m to pH 3.5-5.0, water d / i - up to 1 ml.

5 ml - ampoules (5) - packs of middle contour (1) - packs of cardboard.
5 ml - ampoules (5) - packs of middle contour (2) - packs of cardboard.
5 ml - ampoules (5) - packages of middle contour plastics (1) - packs of cardboard.
5 ml - ampoules (5) - packs of middle contour plastics (2) - packs of cardboard.
5 ml - ampoules (5) - packaging of middle contour (50) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packaging of middle contour (100) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packaging of middle contour plastics (50) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packaging of middle contour plastics (100) - cardboard boxes (for stationary).
5 ml - ampoules (5) - packs of cardboard.
5 ml - ampoules (10) - packs of cardboard.
5 ml - ampoules (250) - cardboard boxes (for stationary).
5 ml - ampoules (500) - cardboard boxes (for stationary).

Inflow to the building of keruvati or vikoristovuvati cars

List of excipes with vidomim effekt

The list of additional speeches with a visible effect: kaliy metabisulfite. Instructions for the correct Victory Day. Dozuvannya koriguєtsya lіkarem at the presentation of key tributes. There is no interruption to internal infusion, even if the pump is available with a permanent speed.

Overdose symptoms and instructions

It is recommended to do the pinning. Nudota, blues, quickened sercebitty, high blood pressure. At the connection with "quick activation of dopamine, just change it or" pin the infusion.

Instructions for oversight of one or more doses

to describe side reactions... Chi is not buzzing, but in case of overdose, turn on nudota and vomiting, a decrease in the diameter of blood-bearing vessels, a breakdown in the rhythm of the heart, an attack of angina pectoris.

List of information required before receiving

Low flow syndrome includes in itself. For heart surgery, shock for carrying infectious diseases, for epidural anesthesia and spinal cord. Mechanic reversal code for alarming a wikidus of a lactic acid, especially obstructive cardiomyopathy, aortic valve, allergy to dopamine. Cycles, as a rule, are not recommended in the context of association with anesthetic agents, antidepressants, guanethidine, and we will tie them to them.

Rules for victorious items, special measures

Accelerated atrioventricular conductivity: it can lead to increased activity of slugs in ailments from fibrillation or trifling of ectopic activity, dopamine to the possibility of accepting or provoking slugs Serious breakdown of the rhythm: the patients with such a history will be especially controlled from the uninterrupted recording of the EKG. Cei lykarsky drug revenge 17, 5 mg of calories in 5 ml of the size taken until the respect in the normal ratio.

Pharmacological diya

Cardio-tonic, hypertensive, vascular dilatation, diuretic.

Zbuzhuk beta-adrenergic receptors (in small and medium doses) and alpha-adrenergic receptors (in large doses). The improvement of systemic hemodynamics is to produce a diuretic effect. There is a specific stimulating inflow on postsynaptic dopamine receptors in smooth muscles of sudin and nirkah.

Manifestations of the presence of sulfite, risky allergic reactions, including systemic allergic reactions to reactions. Zavdyak on the appearance of a caliber, a possibility of phlebitis, or pain in the point of in'n'ktsii. As far as some of the side effects become serious, if you have remembered whether you have a side effect, not on the whole list, look at your doctor or a pharmacist.

If necessary, the reduction of against visible signs of destruction

Zberigati out of reach for children. Niyakikh special zapobіzhny calls for zberіgannya. People who are not guilty go through the water or by the way. Feed your pharmacist with non-perishable liquids. Tsi come in to help clean up the navkolishnє middle.

At low doses (0.5-3 mcg / kg / xv), it is important for the dopamine receptor, the widening of the nirkovy, mesenteric, coronary and cerebral vascular tumors. Expansion of nirok nirok to make it possible to improve blood flow, increase fluidity of filtration, increase deiurez and vivedenny of sodium; There is also an extension of mesenteric vessels (the process of dopamine on nirkov and mesenteric vessels of the development of a series of catecholamines).

A renewed list of active speeches and napovnyuvachiv

Neurology - Lykarnya Vayo di Fidenza - Azl Parma Ambassador for Parkinson's ailment - Az. Tremor to be repaired in distal views kintzivok, for which sub'єkt, to build, vvazhaє coins. Parkinson's ailment є to other neurodegenerative ailments caused by Alzheimer's ailments and enemies more than a few children, who are close to 1000 in Emilia-Romagna. In the industrialized regions, the reloading is close to 0.3% of the outlying population, up to 1-2% in people older than 70 years. In the world of old people there are a number of people who have become ill, to cleanse themselves, to be inspired by the stretch of the coming 30 years.

At low and medium doses (2-10 μg / kg / hv), postsynaptic beta 1 -adrenoreceptors are stimulated, as well as a positive inotropic effect and improved blood volume. Systolic arterial vise і pulse vise can move; at the same time, the arterial grip does not change or grow slightly. Zagalny peripheral op_r of sudin (OPSS) does not change. Coronary blood flow and recovery of myocardium, as a rule, increase. At high doses (10 mcg / kg / hv or more), the stimulation of alpha 1 -adrenergic receptors is replenished, the increase in OPSS, the frequency of the heart rate and the sounding of nyrcovascular vascular disease (it is possible to change the blood pressure earlier). As a result of the increase in blood volume and OPSS, it is growing as a systolic, as well as a diastolic arterial vise.

The strongest link between the proportions between the second dopaminergic cells and key symptom Parkinson's ailments. Such a rank, the acute phase of an illness, is called a pre-motor, in which a neuron is injected has not yet been assigned, but there are classical motives, symptoms of an illness, so that tremors, a tendency to ruin, a bitter and postural instability. Such symptoms tend to become one-sided, to slip on the opposite side in the offensive of fate, and the establishment of pharmacological therapy - to reduce the intensity, to get rid of the sick in a short state of self-sufficiency.

An ear of a therapeutic effect - 5 minutes by a stretch of 10 minutes.

Pharmacokinetics

Introduced only internally. Nearly 25% of the dose will be absorbed by neurosecretory vesicles, hydroxylated and norepinephrine will be released. It grows widely in organism, often passes through the hematoencephalic bar. Explicit volume of rospodil (novonarodzheni) - 1.8 l / kg. Linkage with blood plasma beads - 50%.

The progress of the disease in the skin patient, and with the help of the pharmacological treatment, I am confident about the course. However, the results in the main boule were tied with a symptomatic drug, and not a real internal neuroprotective effect. After 6 months, Rasagilin was administered at a dose of 2 mg of the group, which eliminated placebo, with a design called on the cob... One group of patients, who were looking for therapy for the supplementary drug Rasagilin 2 mg in 6 months, showed more high estimates, lower than that, taking the drug from the ear itself.

It is rapidly metabolized in liver, blood plasma and blood plasma by monoamine oxidase and catechol-O-methyltransferase to inactive metabolites. Period of preparation (T 1/2) - for ages: from blood plasma - 2 minutes, from organism - 9 minutes; novonarodzheni - 6.9 min (between 5-11 min).

Vivoditsya nirkami; 80% of the dose - in viglyad metabolites lasting 24 years, in insignificant quantities - in an unchanged viglyad.

If a neuroprotective effect can be disguised as a symptomatic one, the results, until the end of the day, allow for a hypothesis about acrimony for the patient. early ear therapy, which will be confirmed by analogous advances in the future. As the idea of ​​early treatment of Parkinson's ailments, it is really, in the closest possible, unimportant population, sick to the risk of becoming ill, promoting non-motor symptoms and correcting neuroprotective treatment for this disease. In the last year, less than 60 people were wary of Parkinson's ailments.

showing

- shock of a dangerous genesis (cardiogenic shock; for renewal of the BCC - hypooperative, hypovolemic, infectious-toxic and anaphylactic shock);

- gOSTra heart-sudinna lack;

- syndrome of "low heart wikidu" in cardiac ailments;

- arterial hypotension.

Experts found that 71.8% of them had a lot of symptoms, such as tremor and dullness. 41% of the patients, who were ill, suffered, two times before the diagnosis, two or more "pain" at once. Result until the end of the day confirm the idea about those who key to show Parkinson's ailments are antecedent non-symptomatic preclinical phase, which may occur even at an earlier stage early ailments, Yaka will not be able to diagnose this year. At the end of the day, it was set, until the middle hour was given to the present symptoms. rukhovoy apparatus and by diagnosis I change one pik.

Prototype

- sensitivity to the components in the preparation has been adjusted,

- thyrotoxicosis,

- pheochromocytoma,

- tachyarrhythmia,

- Fibrillation of shlunochkіv.

Do not go to sleep with arrhythmias in combination with MAO inhibitors, with cyclopropane and halogen-containing substances for anesthesia.

Z protection

International non-patented name

Hypoxia. The agonists of dopamine went to the pharmacopoeia of Parkinson's ailments in the late 1970s for the additional bromocriptine, which became the first agonist of dopamine, a kind of sales. Dyisno, still in the 1950s the rock of Bula was home to another molecule with the powers of dopaminergic agonists, Apomorphin, Ale її Vikoristannya Bulo obmezhene side effects byproducts of the slurry, removed after oral administration. On the way out of levodopia, decarboxylate into dopamine on a swarthy level, and then move into the space of neurons, in the agony of dopamine to jump into the first process, without any mediocre delivery to the post-synaptic receptor.

Gіpovolemіya, virazheny stenosis girla aortic іnfarkt mіokarda, torn down rhythm sericite (shlunochkovі aritmії, fіbrilyatsіya peredserd) metabolіchny acidosis gіperkapnіya, gіpoksіya, gіpertenzіya in the "small" koli krovoobіgu, oklyuzіynі zahvoryuvannya sudin (in addition chislі atherosclerosis, tromboembolіya, oblіteruyuchy trombangіїt, regional endarteritis, diabetic endarteritis, Reynaud's ailment, frostbite), diabetics, bronchial asthma (also in anamnesis of adolescence, sensitivity to disulfite)

Courinnya i dofamin

on in different stages Infections of neurons in the nitro-swarthy system, the growth of levodopia before the disease and the increase in levodopia blood concentration is mainly associated with blood concentrations of levodopa. At the present time, it was established that impulse stimulation lies at the heart of dyslexia and motor carriages, it's just a matter of bringing developmental awareness to primates. The robot is self-supporting, so the impulse stimulation is closely tied to the diagnosis of dyskinesias, but also those that are important and the methods of introduction are important for the period until the period of the preparation.

sundown

Introduce internally in drops. The dose is set individually, fallen asleep at the severity level of shock, size arterial vise and the reactions of the sick person to the addiction.

for making it possible for deiuresis and rejecting the inotropic effect(Increased speed of myocardial activity) to inject 100-250 mcg / hv (1.5-3.5 mcg / kg / hv) - the area of ​​low doses. at intensive surgical therapy- 300-700 mcg / hv (4-10 mcg / kg / hv) - the area of ​​average doses; at septic tank- 750-1500 mcg / hv (10.5-21 mcg / kg / hv) - area maximum doses... Z I'm pouring into AT It is recommended to adjust the dose up to 500 mcg / xv and more, for with a sustained dose of dopamine, norepinephrine (norepinephrine) is indicated at a dose of 5 mcg / xv at a patient's weight of close to 70 kg.

Agony to dopamine can be divided into two main classes: agony agony, so that it is eliminated from the horned and nergolic life. Through the risy of the heart valvulopathy, the stench is actually not enough to get into the common practice in the interests of nergic drugs, such as ropinirol, pramipexol and rotigotin.

Dopamine and dopamine

One of the main accelerators of levodopia є dyskinesia, mimic rukhs That can lead to serious acceleration, such as fall, fracture, loss of vagi and buty in the edge not to destroy the quality of life of patients. The stench of victories with modifications of dopamine receptors, as they become overtaxed, vicious with pulsation stimulation, associated with a short period of time when levodopia is given. For the resolution of these problems, stretching out yak at least three ten years early stage therapy of Parkinson's ailment with drugs for a longer period of time for levodopia: agony to dopamine.

In case of failure heart rhythm, Independently from the doses taken, further away from the increased doses are contraindicated.

children injected in doses of 4-6 (maximum 10) mcg / kg / min. For every grown-up person, for children, the dose should be adjusted step by step, so that, repaired at the lowest dose.

The speed of the introduced step is individualized to achieve the optimal response of the patient. In most patients, the patient is given a normal stump when the doses of dopamine taken are less than 20 mcg / kg / min.

Intercourse with other medicines

Dopamine volodymy is less effective, less levodopa on motor symptoms, but also reduce the development of motor acceleration, so that the risk of collapse and dyskinesia. The data obtained from the non-pending and confirmed results of a number of great multi-center diseases, which showed that the growth of both ergolins and non-nerve agonists in dophamine can reduce by about 40% the number of dyskinesias from the ear of 3-5.

The triviality of stagnation: the triviality of the infusion to lie in the individual characteristics of the patient. Є positive admission of infusion triviality up to 28 days. The process of stabilization of the clinical situation is applied to the drug in a step-by-step manner.

Rule for making a cut: for breeding vicoristovuyt 0.9% razchin sodium chloride, 5% razchin glucose (including sum), 5% razchin glucose per Ringer's lactate, razchin sodium lactate and Ringer's lactate. In order to prepare doses for infusion of 400-800 mg of dopamine, it is necessary to add up to 250 ml of the drug (concentration of dopamine will be 1.6-3.2 mg / ml). preparing infusion it should be carried out without a second before the victorious ones (the stability of the range takes 24 years, with the blame of the sum of the Ringer lactate - a maximum of 6 hours). Rozchin dopamіnu is guilty, but we can see through and without barriers.

Pobichna diya

Three sides heart-vascular system: Mensch often - stenokardіya, tahіkardіya abo bradikardіya, sertsebittya, bolі retrosternal pіdvischennya abo znizhennya arterіalnogo vise torn down provіdnostі, rozshirennya QRS complex (QRS - Persha phase shlunochkovogokompleksu scho vіdobrazhaє protses depolyarizatsії shlunochkіv), vasospasm, pіdvischennya kіntsevogo dіastolіchnogo vise in lіvomu shlunochku ; with high doses of zasosuvanny - shlunochkova or suprashlunochkova arrhythmias.

On the side of the herbal system: more often - nudota, blues.

On the side of the central nervous system: more often - head b_l; Mensh often - anxiety, rukhove zanepokonnya, mіdrias.

Allergic reactions: in patients with bronchial asthma - bronchospasm, shock.

Інші: Mensh often - zadishka, azotemia, polyorectia, rarely - polyuria (when administered in low doses).

Miscellaneous reactions: when consumed with a drug for a shkir - necrosis of a shkiri, a pediatric klitkovini.

Overdose

symptoms: superficial blood pressure, spasm of peripheral arteries, tachycardia, shlunochkov extrasystole, angina pectoris, dyspnoea, headache, psychomotor stimulation.

lykuvannya: in connection with the rapid development of dopamine for the organism of the disease, it can be stopped with a change in the dose or the introduction, in case of ineffectiveness - alpha-adrenergic blockers of a short period (in case of overwhelming adrenergic disorders) of arterial hypertension

lykarska vzaєmodiya

Pharmaceutically insane with puddles (inactivate dopamine), oxidizing agents, saline salts, thiaminom (spraying vitamins B 1).

Sympatomimetic effect of adrenergic stimulants, іngіbіtory monoaminoxidase (including furazolidone, procarbazine, selegilin), guanethidine (improvement of triviality and improvement of cardiac stimulation); diuretic - diuretics; cardiotoxic effect - іngalyatsіynі lykarski zasobi for backward anesthesia, abstraction in carbohydrates - such as cyclopropane, chloroform, enflurane, halothane, isoflurane, methoxyflurane (stimulating the development of important anterior anterozoal arrhythmias), antihypertensive arrhythmias arterial hypertension abo hyperpyrexia), cocaine, іnshі sympathomimetics; lax - butyrophenoni and beta-blockers (propranolol).

I will weaken the hypotensive effect of guanadrel, guanethidine, mecamilamine, methyldopi, alkaloids of rauwolfia (stop prolonging the effect of dopamine).

With a one-hour consumption of levodopa - an increase in the development of arrhythmias; with hormones thyroid gland- you can get better for dying yak dopamine, as well as hormones in the thyroid gland.

Ergometrine, ergotamine, methyllergometin, oxytocin reduced vasoconstrictor effect and risk of vasoconstriction and gangrene, as well as important arterial hypertension, right up to intracranial hemorrhage.

Fenitoin can accept the development of arterial hypotensive and bradycardia (stale in the form of dosage and supplementation); alkaloids of rіzhkіv - ringing of the sudin and development of gangrene.

Sumy with heart glucosides (it is possible to increase the risk of arrhythmias of the heart, an additive inotropic effect, control over the EKG is required).

Decrease antianginal effect of nitrats, as in its own capacity there can be depletion of the most recent effect of sympathomimetics and hypotension risk of arterial hypotensiveness

special requests

Before the introduction of ailments, as we are in a shock station, hypovolemia is to blame for the speed of the injections of blood plasmas and blood cells.

Infusion is guilty of being carried out under the control of duresis, frequency of heart disease, blood volume, arterial vise, EKG. The change in dyuresis without a concomitant reduction in the arterial grip depends on the need for a change in the dose to Dofamin.

Іngіbіtori monoamіnoksidazi, pіdvischuyuchi pressor efekt simpatomіmetikіv, mozhut obumovlyuvati viniknennya head bolyu, aritmії, blyuvoti that іnshih proyavіv gіpertonіchnogo crises, that have patsієntіv, SSMSC otrimuvali protyagom ostannіh 2-3 tizhnіv іngіbіtori monoamіnoksidazi, pochatkovі Dozy Dofamіnu povinnі skladati not bіlshe 10% od zvichaynoї Dozy ...

Strictly control of the prescription of the drug in patients under 18 years of age has not been carried out (about the occasion of the diagnosis of this group of patients in arrhythmias and gangrene with the introduction of an intravenous drug)

To reduce the risk of extravasation according to the possibility of entering it into large veins. For the prevention of tissue necrosis in the case of extravasal consumption, the drug should not be inaccurate to infiltrate 10-15 ml of 0.9% sodium chloride solution with 5-10 mg of phentolamine.

Priznachennya Dofamіnu on tlі oklyuzіynih zahvoryuvan peripheral character sudin i / abo DIC (FEP - dessіmіnіrovannoe vnutrіshnosudinne zgortannya) in anamnezі Mauger viklikati rіzke i virazhene zvuzhennya sudin scho will only be sold to necrosis shkіri that gangrene (slіd zdіysnyuvati retelny control, while viyavlennі Find our periferichnoї іshemії the introduction of the drug inaccurately pinch).

In the stolen light of the mice at temperatures from 8 to 25 ° С. Term of attachment - 3 rocks.

Drug: dopamine (DOFAMINE)

Speech active: dopamine
ATC code C01CA04
KFG: Dopamine and adrenergic drug
Registry. number: LP-000444
Restoration date: 01.03.44
Vlasnik reg. certificate: BINERGIYA (Russia) virobleno ALTAIR (Russia)

LIKARSKA FORM, WAREHOUSE І PACKING

5 ml - ampoules (5) - packs of middle contour (1) - packs of cardboard.
5 ml - ampoules (5) - packages of middle contour plastics (1) - packs of cardboard.
5 ml - ampoules (5) - packs of middle contour plastics (2) - packs of cardboard.
5 ml - ampoules (5) - packs of middle contour (2) - packs of cardboard.
5 ml - ampoules (5) - packaging of middle contour plastics (20) - cardboard boxes.
5 ml - ampoules (5) - packaging of middle contour plastics (25) - cardboard boxes.
5 ml - ampoules (5) - packaging of middle contour plastics (50) - cardboard boxes.
5 ml - ampoules (5) - packaging of middle contour plastics (100) - cardboard boxes.

DESCRIPTION OF ACTIVE SPEECH.
Science information has been introduced є publicity and it is not possible for a vicoristan to accept the decision about the possibility of storing a particular drug.

PHARMAKOLOGICHNA DIA

Cardio tonic and hypertensive Agonist of dopamine receptors, endogenous ligands.

At low doses (0.5-3 mcg / kg / hv), it is important for the dopamine receptor, the widening of the nirkovy, mesenteric, coronary and cerebral vascular tumors. In addition to the specific infusion on the peripheral dopamine receptor, changes in the opiate of nirkovy sudins, the blood flow in them, as well as the glomerular filtration, in the formation of sodium and diuresis; There is also an extension of mesenteric vessels (the process of dopamine on nirkov and mesenteric vessels of the development of a series of catecholamines).

At low and medium doses (2-10 μg / kg / hv), postsynaptic beta 1 -adrenoreceptors are stimulated, as well as a positive inotropic effect and improved blood volume. Systolic AT і pulse clutch can move; at the same time, the grip does not change, for it does not grow slightly. OPSS will not change. Coronary blood flow and myocardial recovery are sour, as a rule, increase.

At high doses (10 mcg / kg / hv or more), does the stimulation overload? 1 -adrenergic receptors, cyclic changes in OPSS, heart rate and ringing of nirkovy vasculature (the last can change earlier, nirkovy blood circulation and dyuresis). As a result of an increase in blood volume and OPSS, both systolic and diastolic AT.

An ear of therapeutic effect - with a stretch of 5 minutes per aphid for intravenous infusion and a three-piece for a stretch of 10 minutes.

PHARMACOKINETIKA

Pislya in / in the introduction is widely distributed in the body, often penetrating through the hematoencephalic bar. Nearly 25% of the dose will be absorbed by neurosecretory vesicles, hydroxylated and norepinephrine will be released. Metabolize in ovens, nirkas and T 1/2 with plasmas - close to 2 minutes, with organism - close to 9 minutes. Vivoditsya nirkami: close to 80% for 24 years; the leading rank in viglyad metabolites, a small fraction of the dose is vivod in unconditional viglyadі.

Shown

Shock of a risk of genesis (cardiogenic, hypooperative, infectious-toxic, anaphylactic, hypovolemic / only for renewal of the BCC /). Gostra heart-sudinna lack of developmental genesis, low heart wikidu syndrome in cardiac ailments, arterial hypotensiveness, for strengthening duresis in case of otruunny.

DRUG MODE

Vstanovlyuyut individually fallen asleep in the degree of severity of shock, the magnitude of the arterial grip and the reaction of the ailing to the introduction of dopamine. With the aim of increasing the rate of myocardium and increasing duresis, inject intravenously in drops of 100-250 mcg / min. If there is a need to inject the AT, the dose should be increased to 300-500-700 mcg / min.

Children should be administered at doses of 4-6 mcg / kg / min.

The triviality of storing dopamine can become up to 28 days.

Maximum dose for grown-ups with intravenous spotting introduced, set 1.5 mg / min.

POBICHNA DIYA

On the side of the heart-vascular system: tachycardia abo bradycardia, chest pain, podvyshennya or diminished arterial vise, deterioration of conductivity, enlargement of the QRS complex, vasospasm, podvyshennya kintsevogo diastolic vise in luvus; with high doses of zasosuvanny - shlunochkova or suprashlunochkova arrhythmias.

On the side of the herbal system: nudity, bloating, bleeding from the intestinal tract.

On the side of the central nervous system and peripheral nervous system: more often - head bіl; Mensh often - anxiety, loss of sleep, tremor of the fingers.

On the side of the exchange of words: polyuria.

Allergic reactions: in patients with bronchial asthma - bronchospasm, shock.

Miscellaneous reactions: in case of a dopamine from a school - necrosy of a school, a pedagogue of a child.

Інші: Mensh often - zadishka, azotemia, polyorectia, rarely - polyuria (when administered in low doses).

Prototype

Hypertrophic obstructive cardiomyopathy, pheochromocytoma, fibrillation of shlunochki, increased sensitivity to dopamine.

Viability and LACTATION

In case of vaginosis and in the period of lactation (breast feeding), it is doped to grow only in quiet droplets, if cinnamon is transferred for the mother, the potential for the fetus is changed.

SPECIAL VKAZIVKI

With the protection of patients with hypovolemia, myocardial infarction, heart rhythm disorders (tachyarrhythmias, sleepy arrhythmias, fibrillation of the anterior heart), metabolic acidosis, Gіperkapnії, gіpoksії, gіpertenzії in small koli krovoobіgu, tireotoksikozі, zakritokutovіyglaukomі, gіperplazії peredmіhurovoї zalozi, oklyuzіynih zahvoryuvannyah sudin (including atherosclerosis, tromboembolіya, oblіteruyuchy trombangіїt, oblіteruyuchy endarterіїt, dіabetichny endarterіїt, hvoroba Reynaud vіdmorozhennya) at reddish diabetics, bronchial asthma(Also, in the anamnesis of an increase in sensitivity to disulfite), vaginosity, lactation, in children and adults up to 18 years.

With the manifestation of hypovolemia, it is necessary to compensate for the introduction of dopamine to the ear.

Introduced dopamine slid to be carried out by monitoring heart rate, AT, EKG, the value of dyuresis; it is also recommended to control the vise of the heart, the vise of the vise, the central venous vise, the vise of the legendary artery... Decrease in dosage depends on the need for a decrease in dosage.

On the other hand, the dose of dopamine should change by 10 times.

lykarskim VZAЄMODIYA

With a one-hour zasosuvanny with diuretics, you will be able to sechegіnnu dіyu dopamіnu.

With a one-hour consumption of MAOs (including furazolidone, procarbazine, selegilin), guanethidine can increase the intensity and triviality of cardiac stimulating and pressor effects in dopamine.

Introduce dopamine for tricyclic antidepressants (including maprotiline) to improve the strength of its effects (possible development of tachycardia, arrhythmia, important arterial hypertension).

With a one-hour zastosuvannі z oktadinu will be sympathetic.

Є occasionally about the development of severe hypotension in case of a one-hour stagnation of dopamine with phenytoin.

With a one-hour intake of ingestion for zagalny anesthesia, lost carbohydrates (including cyclopropane, chloroform, enflurane, halothane, isoflurane, methoxyflurane), serous rhizomes develop.

Іnshi sympathomimetics, as well as cocaine lead to cardiotoxicity.

Pohіdni butyrophenone, beta-blockers to change dopamіnu.

Dopamine changes hypotensive effect of guanadrel, guanethidine, methyldopi, alkaloids of rauwolfia (will not prolong the effect of dopamine).

With a one-hour consumption of levodopa, the development of arrhythmias is increased.

With a one-hour consumption of thyroid hormones, it is more possible to strengthen the thyroid gland, as well as hormones in the thyroid gland.

Ergometrine, ergotamine, methyllergometin, oxytocin reduced vasoconstrictor effect and risk of vasoconstriction and gangrene, as well as important arterial hypertension, right up to intracranial hemorrhage.

With a one-hour consumption of heart glucosides, it is possible to increase the development of the heart rhythm, an additive positive inotropic effect.

Reduces the antianginal effect of nitrats, which in its turn can reduce the fresh effect of sympathomimetics and improvement of arterial hypotensiveness.

Pharmaceutically insane with puddles (inactivate dopamine), oxidizing agents, saline salts, thiaminom (spraying vitamins B 1).