Toxic nirka syndrome. Toxic nephropathy: symptoms, diagnosis, treatment, photo Toxic nephropathy nirok history of ailment

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With a quick cut, the area is most often consumed in the group with a further development of toxic nephropathy. Schob uniknuti quickened, for example, fake sales nirkova lacks, it is necessary to quickly turn to fahivtsya. Yakіsnyy course of liking to relieve all negative inheritances.

Nephropathy is toxic - the cut of parenchyma of nirok, glomerular apparatus.

Such a manifestation is typical when the internal and external toxic products, metabolites are removed. In medical terminology, there are two types of disease: specific and nonspecific nephropathy. The first type of dressing with detached toxins, it is not only for nirki, but also for the functional robot of the oven. Nonspecific type of ailment of obumovaniya rozladami in the area of ​​hemodynamics.

I see a great number of awesome elements, such as the building of naughty organisms, the growth of nirok. Besides a part of shkidlivy speeches, like a lyudin nabuva for life, because of them, they can win independently in cases of injuries, due to illness.

1. Among the factors that provoke the development of toxic nephropathy are seen as a result of lykarsky labor. Especially, it is especially important to use quiet preparations, as vikoristovuyut for extra extraordinary medical aid that іnshі.
2. Fakhіvtsі in galuzі medicine is brought to dzherel otnenja microbial organisms. Through the drinking room to the roof, microorganisms will sprinkle the septic tank. The same process of infection can occur during transfusion. The provocation of the development of ailments is insanity by group, or the Rh factor of blood.
3. Otruynі mushrooms є especially not baked, the stench provoke stronger otrunnya organism.
4. Negatively infuse a functional robot with a kind of chemical character, salt important metals... To the whole category, it is also possible to convey the words of a radioactive character.
5. Among the possible reasons for the diagnosis of toxic nephropathy, they see antibiotics for a long time, or anti-microbial drugs. With a trivial implantation of the stench, the shkodi is healthy.
6. alcohol withdrawal low quality, Abo organic fillers. Until the end of the day, add ostatic acid, or tetrachloromethane.
7. Shkіdlivі speeches can winicati pislya important injuries, Abo opik_v. Fabrics repair the process of ruinuvannya, in addition to which products are consumed in the roof of the people.

All the reasons are the main provocateurs in diagnosed toxic nephropathy. It is normal to have a lot of money.

It is necessary to produce it to the point of acceleration, as it is a serious threat to life.

Rivn urazhennya lie in a large world in the type of shkidlivy speech, or whatever way of getting it. Vahomu the role of the standard of the sevidialnoy system. Navigate with a small amount of consumption of branded speech key picture to slow down, as the people are suffering from chronic illnesses in the whole region.

I see the main symptoms of toxic nephropathy:

• show discomfort at the sight of zadishki;
• more views in botsі, in the transverse viddіlі;
• rіzke lower rіvnya arterial vise;
• change of the volume of the battle.

In the case of consuming toxic, or abrasive particles, the symptoms can be manifested in the following way:

• attack blues and boring, there is a lot of shelter;
• Health and pain in the abdomen;
• rozlad to the slunk;
• drowsiness, unpredictability, in general, the brain dullness.

To get involved, nephropathy is toxic to a great shkodi healthy people. The price is right. Illness in case of ignoring provocation of development of hostile nirkova lack.

diagnostics

In the first place, the qualifications of the fahivets turn to symptomatology, because of the reason for the diagnosis of the ailment. At the same time, the following necessary procedures are indicated:

• ultrasound doslіdzhennya nirok;
• analysis of blood and slaughter, as well as biochemical analysis of blood.

The procedure is necessary in order to be able to increase the size of the camp, the accuracy of the nirok, to recognize the same course of treatment.

Often, a number of procedures, for example, MRI, or CT scan, are used to confirm diagnosis.

Technique for the treatment of toxic nephropathy

You shouldn't be bothered to find out, you need to have a shkidliv speech. The procedure is carried out as quickly as possible. Fakhivtsі vіdіlyayut advnі dіevі ways.

• Promivannya otdobnya at vypadkah otruunnya mushrooms, or leaks.
• Vikoristannya antidote. It is a drug that will help you to get rid of the organisms when they are cut off by industrial or chemical words.
• Hemosorbia is a method that is used for cleaning up on cleaned blood from the blood of an active vug.
• See hemodialis. Qia procedure is recognized in important issues.

For the development of diuretic preparations, they reduce the amount of legends (Lasix, Mannitol), as well as full changes, which normalize the pH level in the blood (for these purposes, sodium hydrocarbonate).

Navigating from the "neglected" stones in the nirkas can be done quickly. Just don't forget about vipivati ​​once a day.

The pathogenesis of the disease is a common cause of the etiology of the vine. Through the detachment, for example, etylenglikol is added to the nephron block.

When the process of otrunnya is put through the otrut of a hemolytic character, the nephron becomes clogged. When a lot of erythrocytes run.

At the same time, all visceral factors provoke ischemia of membranes in the nephrons. Uninterrupted ischemia is cluttered with non-gutted patches of necrobotic changes in clusters and canals.

In addition, it means that toxic nephropathy is manifested in children. Have a lot of vipadku varto zvernut uvagu to the warehouse of the battle.

Also toxic nephropathy manifests itself on aphids through recessive pathologies. As soon as in the family of the baby's mother it’s an hour or so until she gets sick, the child’s sickness can also get stricken.

Provocateurs in childish You can be a piece of a year, for some, according to its periodicity, infections, colds, ailments.

professional come in

Okremo varto vidnosti, oh pershu dolikarsku will help none of them are seen. Varto pinch the hopefulness of the branded words into the body of the sick person. It’s because it’s gotten out of steam, that it’s necessary to keep it safe from the other people, it’s innocent to keep it from being attached. Yakshko chemichesky speeches were drunk in a slunker, so a term is needed. Likewise zasosovuyut klizmi, vikoristovuyut assets not vugillya.

Since people have a daily heartbeat, because they have to be without witness, so it is necessary to grow indirect massage heart, piece of business.

At the same time, it is necessary to get medical help from the cimi diami.

In prophylactic visits to virobnitstvah, de є high risik otrunnya shkidlivnye speeches, people are not allowed to go to chills, or to urazhennyam nirok. Most often before such vyrobnitstv there are important silskogospodarsky robots, making rubber, or polymers.

As soon as you practice on such a virobnistvі, de іsnu is a great risky battle nirok, so it is necessary to regularly go through the screening (never before rіk). It is also pleasantly to be recognized in your camp of health by catching hygienic norms, special zhisniy odyag. As soon as you sposter on the cob stage, you will not be able to do it, but you will not be able to do it, but change the robot.

heritage

When you get sick, it is necessary to secretly turn up to a quality fakhivtsya. The lack of provocation over the fight nirok:

• gosstru nirkov lack of, as supervise to act on changes in any way in the world of vision of slaughter;
• I am chronically nirkov's lack, like a vinnik, for an important detachment.

Be-like penetration into the organism of branded, shkidlivy speeches є for possible reasons the development of ailments. In order to be able to unite the speed up, it can be done in a short period of time during the necessary visits.

Heads of advances in the field of modern medicine, ailments are fed to the liking. Varto pam'yatati, which, with the right and quick beasts, is a great chance in the best of the world.

I trochi about secrets.

Have you ever suffered from problems through bіl at nirkahs? Judging by that, you are reading the ciu article - the bullet override is not on your boat. I obviously do not know a bit like this:

• Discomfort і bіl across
• The rankings of denunciations are not enough to give you a song in your own right.
• Yakos navіt rudely, especially since you are suffering to frequent sechovies.
• Until then, the post-weakness and non-mutilation have already disappeared into your life.

toxic nephropathy

1. Specific nephropathy. It is tied with hospitable toxicoses, which can be diagnosed with rejection by small nephrotoxic rivers. Often, the deterioration of the function of the liver develops.
2. Nonspecific nephropathy. Surrounded by the roslads of hemodynamics of the developmental ethology, provoked by the important detachments.

Causes and pathogenesis

• Important metal, їх salts;
• ethylene glycol;
• Shchavlev, otsic acid;
• Pesticides, herbicides;
• mish'yak;
• retailers;
• Midniy vitriol;
• Take away the twarin, coma;
• Toxins of mushrooms;
• Azotovmіsnі spoluki;
• Flying efіri;
• Inconsiderable alcohol.

• Pidvischennya arterial grip right up to the highest digits.
• Change of dyuresu, frequency of sechovipuskan (inodi povna anuria).
• Pain across through the embankment nirok.
• Sudomi.
• Lower heart rate.
• Arrhythmia.
• Wheeze in legends.

1. Persha - about the condition of the child, hemoglobin and erythrocytes in the blood, mild symptoms.
2. Friend - duresis padaє, the amount of sečovina, calories, creatine in the blood is very growing, the symptoms grow.
3. The third - in addition to a large number and a sharp decrease in the indicators of glomerular filtration of the potential development of a hostile deficiency - a mortally insecure acceleration.

1. Initial (up to 3 days). Vidbuvatsya vlasne otrunnya organizm nephrotoxic agents.
2. Oligoanuricheskaya (1-2 types). Through the closure of the line, the vision of the slaughter is reduced, so that the heart and the development of the nagging, zadishka, wheezing in the legends are brought up to the overwhelming. At the ts_th stage, the brain is also full of energy. Death is trapped in the form of breath with the build-up of legends, in the form of a heart, DIC syndrome. Often there is secondary vasculitis, anemia, thrombocytopenia.
3. The stage of polyuria (up to decilky months and rocks). This stage is infused at friendly perebіgu ailments. Direz build-up, which can also lead to feverishness.
4. Oduzhannya. All indicators of slaughter and robots will return to normal, moreover, it is not possible for all ailments to be renewed.

diagnostics

• Zagalny analysis of blood, slaughter;
• Blood analysis for pH level, electrolytes;
• Biochemistry analysis of blood in the part of indicators of robots;
• Ultrasound nirok;
• If necessary - MRI nirok.

• plasmapheresis;
• hemodialis;
• hemofiltration;
• hemosorption;
• Promivannya shlunkovo-intestinal tract.

Folding and forecast

Foldable nirkova dysfunction, viclikana with chemical or organic speech, I will call it toxic nephropathy. There is a wider spread of the nirk system, according to the statistics on the th part of the attack 30% of the nirok disease. І s dermal rock and numbers may mean the power of growth. Danish ailment develops in the form of a rakhunka, similar to clitin with toxins and grains, and is often introduced through the system of the intestinal tract, dickheads, Through pori.

Classification

Nephropathy can be divided into two types: specific and nonspecific syndrome. Until the first time, you can see the bran, tied with branded words, such as mercury, lead, chemical acids, vitriol, mish'yak and іn. Through the intoxication of the organism, the robot will break down and the liver. With a different type of rejection, an excess of hostile speeches will come up with a rejection, and possibly hemodynamic damage (bite from comas, snakes, intoxication with mushrooms, low purity, alcohol overdose).

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Causes and pathogenesis

The reception of lіkіv stretching out a trivial period can provoke a sickness.

Otruynyh spoluk, wiklikayut nirkovy pathologies, a great spectrum. A lot of them settle in the house in the process of living of people, and as if they bathe when they carry ailments. Looking at the disease may manifest itself as an overdose lykarskiy zasobami during the period of passing the course of therapy, if only one-time help is provided. The most common reasons for the diagnosis of nephropathy є:

the penetration of branded words into the middle of the organism as a result of implantation in the hedgehog of bran mushrooms; drinking in stravohid or through a shkir of toxic chemical spoluk; otruunnya, wiklican with important metal salts; radioactively infected; Infectious diseases excess alcohol in the blood; living the faces by stretching the trivial period; after the procedure of blood transfusion, yak did not go for the characteristics; strong shkirni ears (wounds, opikas), which pulled the infected blood behind them; drinking alien microorganisms into the blood.

Toxic from children

Okremo varto will show this disease in children. In the first place, the child's organism appears in the womb of the slaughter. The weakness of children to the nephropathic syndrome is overwhelmed by recessive pathologies in the nirk structures, either with congenital lesions of the sechostatus apparatus, or similarly, the child's mother has become painful for hours. I stimulate the development of vidhilen in children piece vigodovannya, Parts of infectious colds.

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Symptoms of toxic nephropathy nirok

Bile on the back in the area of ​​low is the most common symptom.

You will always be able to get some inherited inheritance, you need to know the symptoms of nephropathic intoxication. And such є:

oligoanuria - a syndrome of a decrease in the number of children, which is seen by an organism during urinary tract; lack of strength - a low grip in the arteries; slowdown not dichannya; strong and weak pain in the area of ​​nirok; positive to blues, emptying the slunk with the appearance of bloodshed; diarrhea; more visions in the area of ​​sleepy gossip; you may be uncomfortable, weak, sleepy.

Storage and inheritance

For the nephropathic syndrome, the development of such diseases, such as bacterial tissue damage in nirkas, hemolytic anemia and thrombocytopenia, and hypertension nirkova deficiency, is accelerated. Nirkovi dysfunction is accompanied by pains of a small step in the area of ​​the base of the ridge, inappropriate views in the slopes, vіdhilennymi at sechovipuskannі, as well as a low grip, besides, the ailing can freeze. With the inoculation of a blood depot, it is possible to promote under-infestation and increase in the number of leukocytes.

Functional uremia can be the cause of a lethal result for the patient, since symptoms have appeared - lykarska additional help is required. Vaughn to bring to the development of dysfunctions of the nephrons, or even more in the robotic organ. Symptoms of such an incidence are: a decrease in the number of slags, an unpleasantness in the production of toxins and slags by the body, a decrease or an increase in acidity, anhydrous water. Nyrcovy necrosis develops on the basis of such dysfunction, which is an important inheritance and possibly a cause of death.

With the manifestation of this disease, the nirk system is in the middle of the earth.

Otruunnya part of the wine through the damage to the body with toxic products is hateful, but the reason for the increase is the overdose of the disease or the disease, which was given by the seryoznі slowdown. With the development of toxic nephropathy in Pershu cherga, the nirkova system is hungry, and the following inherits are used:

Gostra nirkova lack. It is characterized by problematic secular problems - the number of vivered births is very low, as much as the process of seeing urine is replenished. It can be developed with acute renal failure, as a syndrome of acute aggravation. For the old pidsumkom of intoxication with a low level of symptomatology.

diagnostic methods

In case of medical care, respect for the diagnosis of toxic nephropathy. It is necessary to be more precise about a substitute, which has become the cause of the destruction of organs. For the determination of the factors, it is necessary to develop a mental analysis of the slaughter, to take shelter for preliminaries for the appearance of anemia and leukocytosis. Besides, it will be carried out to determine the cause of the syndrome. It is necessary to provide a more thorough camp of nephrons and their functions - an analysis of blood behind a biochemical warehouse. It is possible to carry out an ultrasound scan for nirok. If necessary, additional clarification should be carried out by tomography and X-ray. However, in a great deal of problems, it is necessary to give the nobility a frustrating factor and to analyze them and show ailments.

If an overdose was inflated to the smallest detail, or the apparent ill-health gave an acceleration, it was required to bring out of the mouth the blast of speech, which would stimulate the rush of blood to nirok. If the reason is more flexible, it is also necessary to put pressure on the key minds, the term of the patient's reanimation may be possible. Wiklikan's ailment to the chronic form, Lіkuvannya to lay down in the specific processes that run through in the organs, and the nature of the changes that occur.

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Yake zasosovyut lykuvannya?

The most popular method of first aid is the washing of the slunk.

We are happy with the treatment of nephropathic detachment, neutralization of refractory factors and extraneous weakening from the body. Medical assistance at such a moment is necessary immediately. Axis of newest come in first help when wears off:

Promivannya shlunka - Yakscho potrapili toxins into the blood through yadosoderzhaschey їzhі abo velikoї kіlkostі lіkarskih sredstv.Prі strong sorbent vivodit otruti - at hіmіchnih іntoksikatsіyah abo otruєnnyah Promyslova othodamі.Prіem aktivovanogo vugіllya abo gemosorbtsіya - dopomozhe Vivest toxin SSMSC potrapili in krov.Prіmenenіe Pristrom " shtuchna nirka "- vikoristvutsya in nayvazhchih vipads.

Toxic nephropathy is not safe for the patient's life. At times, if there is a NEPHROTIC stroke, you cannot do without a high-quality training. The most popular methods classroom policy vvazhayutsya vikoristannya " piece nirka»I detoxification for the additional help of an active person. These methods give the ability to extrude the grated components into the body. If you are far away to neutralize, come in quickly, there are hundreds of pleasant heritage. Predict loyalty in such cases. Possibility of renewal to run.

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Forecast and prevention

Severe dysfunction may be due to low factors. Have a lot of fallowing and varto live preventive visits. Chast_shayut vypadki mushroom offal. Tse vіdbuvaєtsya through zbirannya wildweed species, as vyavlyayutsya otruynymi. To that end, the grave inheritance of the need to be surrounded by the implantation of the whole day is unified. Overdosing with lykarsky preparations of vinikє in case of self-mediated treatment and reception of highly vigorous diseases. To that, before implanting tablets, or mixtur safely, read the recommendation of Fakhivtsya.

Parts of the striking of the nirkovy apparatus are found on the chemistry devices. This kind of work is shown to people who are sick before the development of oncology or the development of nirkovy dysfunctions. To make sure that the workers from the detachment can use the technical mechanics of the work, so that you can make more contact with the tools. In quiet people, if there is no intermittent contact with the spinal chasm, it is necessary to undergo regular preventive reconversions of the nephrotic system. It is necessary to prey on its own; Varto dotrimuvatisya installed safety technology. As well as in the body, pathological changes are always seen, more beautifully changing the sphere of activity. If symptoms appear more beautifully, they immediately turn up to the disease, so it is possible that additional help is needed immediately.

Ethiological officials of the industry can reach numbers and can be united in the onset of larger ethiological and pathogenetic groups.

I. Shokova nirka. ARF develops in case of traumatic shock with massive tissue loss, waste blood, plasma, tissue origin and reflex shock, which can lead to hypovolemia and hypotonia, venous and arterial blood loss, as well as in superficial hemorrhage. It is especially often to be spared in case of serious illnesses and injuries, important operative injuries, cases of abnormalities of the liver tissue, fatigue, in case of myocardial infarction and hematologic disasters, severe vertebral disasters, ...

II. Nirka is toxic. OPN is diagnosed with such nephrotropic spines, such as mercury, propylene glycol, bertolethous salts, sulfanilamides, etc.

III. Gostra infectious (infectious-toxic) nirka... Gostra uremia can develop with distant hemorrhagic nephritis, Weyl-Vasilyev's ailments, anaerobic infections, which can prevent arterial vices from falling, collapse. Anaerobic infection is often superficial, as well as proliferation of malignancies, criminal abortion.

IV. Sudden obstruction. ARF can be diagnosed with nirkovy vasculitis, severe scleroderma nirti, malignant hypertension with burhliv Arteriolonecrosis, with total measles necrosis in vaginal patients, pyelonephritis with necrotic panillitis.

V. Gostra obstruction of the sečovyh nobles. Also spriy OPN sulfanilamidna nirka, sechokam'yana ailment etc. D.

In the given hour, it is more common to stop parasitic arresters on prerenal, renal and postrenal, which are permitted, especially in the case of pre- and postrenal arresters, in case of pre- and postrenal arresters, as a result of pre-renal arresters. The main causes of the arrester are suspected to be seen by the groups below.

I. Prerenal arrester

1. Signs of lack of tissue perfusion, lowering of CF and low central vice

Olighemic shock of blood, opic, loss of water and electrolytes in cases of bloating, diarrhea, fistuli of sludge, cardiogenic shock, infarction of myocardium, embolism of the lung artery of all bacterial shock

2. Vipadas from the fall of KF, ale without hypotonia

Deficiency of water and salts of Gostra hypercalcemia

II. renal arrester

1. Hostrium tubular or cortical necrosis

a) shock from uncorrected prerenal ARF:

surgical trauma and diagnoses of blood loss or birth septic shock gostry pancreatitis

b) hemoglobin or myoglobin:

blood transfusions accelerated hemolytic anemia

c) nephrotoxic speech:

chotiricchloride in inorganic carbon inorganic salts of mercury important metals ethylene glycol lykarski speech (antibiotics, phenacitin, sulfanilamide drugs)

2. Blockade of tubules, for example, urates, sulfanilamides

III. Postrenal arrester

Nirkovy stones Retroperitoneal fibrosis Pelvic organ fluff

For the most common reasons, surge arresters can be found in most demanding mills. So, S. Dean і spіvavt. (1977) sped on the development of oliguria and those signs of a hostile and nirk disadvantage among young people, which is a deterioration without peace in a sauna. Efficiency of blood transfusion is not caused by hemolysis only as a result of blood transfusion acceleration and removal of hemolytic branches. Hemolysis with a similar transient arrester S. Owusu і spivavt. (1972), as well as O. Selroos (1972) prevented patients with glucose-6-phosphate dehydrogenase deficiency (G-6-FDG) erythrocytes in ailments, and T. Pollard and I. Weiss (1970) - in marathon runners with tricky scoring.

It was not only in case of injuries that the breakdown of the mucous membranes with the thunderbolt and the myoglobinurium winners was caused. S. Leonard and E. Eichner (1970) spasmed at march and idiopathic rhabdomyolysis, and N. Kopsa and spivavt. (1977) - when frozen. . Nephrotoxicity of antibiotics - gentamicin, neomycin, rifampicin, colistin, radiopaque speech, which can become stagnant in case of pretreatment of sufferers, malignant and secular habits, products of detoxification of young anesthetics

In some cases, lykarsky nephrotoxins penetrate into the body in an unwavering way.

V. Bornshewer and spivavt. (1975) spared a sick person who, in conjunction with an infectious disease, was given a drug to avenge mercury. After 2 months, symptoms of mercury intoxication developed, as well as oliguria and development of nitrogenous slags in the blood. The manifestations of a hostile lack of self-consciousness became aware of the appearance of a love affair.

A. Barrientos and spivavt. (1977) described the development of a hostile deficiency in a 28-year-old man;

If you have a lot of money Lykarskiy rechovin Defeat nirok with the development of a hostile nirkova deficiency may be allergic genesis.

P. Faarup і E. Christensen (1974) cite the history of ailments of myocardial infarction, in which phenobarbital viklicalo will have visipa, oliguria, azotemia. In case of punctual biopsies, a picture of gastrointestinal tubulointerstitial nephropathy with ignited infiltrates near the Sudins is revealed. Prescribing a barbіturatu and the appointment of prenіzolone and antihistamines led after 3 additional renewal of the function of nirok.

Blockade of tubules with urates develops in case of immunosuppressive drug treatment new options severe leukemia is described in individuals who have not been acclimatized to spec, before an hour of important physical robots.

Obstruction of cuttings with D. Levin candida and spivavt. (1975) spared a sick person with a decrease in immunological reactivity in the past radioactive iodine in conjunction with thyrotoxicosis.

Of particular importance among the causes of acute renal failure is a major pathology.

Dzherelami emboli with embolism of the nirkovo artery can be in front of the heart in case of mitral stenosis, vegetation from the valves of the heart with endocarditis, atheromatous aorta was seen. Oscillations of the embolism of the nirkovo artery often develop at once from the embolism of the other organs, and it usually grows even more rarely. According to N. Hoxie and S. Coggin (1940), only in 3 out of 348 vypadki vyavlenih on the rosette of the embolism of the nirkovo artery, the diagnosis of the incidents for the life of ailments. One-sided embolism of a nirkovo artery does not lead to a hostile nirkova disadvantage; you can only in the times of a two-sided battle, as if there was an occlusion of the artery of a single nirka.

We are sick with adolescence for an embolism of nirkovy arteries, it is necessary to carry out an aortography inaccurately, it will be seen as soon as possible in 12 years, and in case of partial occlusion - through a few days of the new function of nirk.

In case of resection of aortic aneurysms, acute renal failure, which develops in 17-24% of cases, can be associated with thrombosis of the nirkoval arteries, as well as severe tubular necrosis through the collapse during an hour of surgery, etc. , state of pancreatitis, State of Dissemination of Internal Vascular Coagulation.

In newborns, thrombosis of the nircoval arteries is often associated with gastroenteritis and dehydration. Yak and thrombosis of nirkovy veins, it can lead to severe nirkovy deficiency in a single unilateral injury. As many as half of the described types of thrombosis of nircovy veins are more common in children. Some thrombosis develops in the first year of the nation's life, rosy, in utero, and often starts in the first month of life. To fix thrombosis from pains in the area across, fever, dyspeptic disorders on dehydration (high hematocrit).

Often, thrombocytopenia, elevated prothrombin hour and coagulogram changes, are spontaneous. A block and erythrocytes appear at the sech. Nirka zbіlšena in size, but not to be confused contrasting speech with internal urography. On the retrograde pellogram one can see the pressure of the calyx, extravasation of the contrasting speech in the parenchyma, the blood clot in the ball. The prognosis, as a rule, is unpleasant. Thrombectomy for phlebography - ekstrena mira, Zdatna protect one, or navіt grievances nirki. In case of a one-sided process, it is blown up to nephrectomy. Odorlessness is possible at conservative lіkuvannі This includes the therapy of the main disease, rehydration, anticoagulants, and the fight against symptoms of uremia.

In grown-ups, thrombosis of the nircovine veins should be repaired and brought to nephrotic syndrome in the endocytic vein until CNI. ARF develops in two types - non-reversible in case of vein thrombosis on the smallest apparent amyloidosis or even thrombosed veins of the nirk graft. In general, fast thrombectomy changes the function of the graft.

At nemovlyat ARN can be also a lot of perinatal asphyxia. T. Dauber і spіvavt. (1976), when they spied 7 such types of problems, they established an interchange of functions in 5 patients after 12 months after the transferred hostility or disability.

Malicious hypertension even in the early stages can be accelerated by the surge arrester with the development of oliguria. An extensive therapy with hypotensive drugs has been introduced, and hemodialysis of a peritoneal dialysis allows one to consider a trivial remission and polypsychitis function of nirok in a number of types. It’s not possible to be renewed, and it’s not safe to fight the vertebral bottom and to lose sight, to go to bilateral nephrectomy with regular hemodialysis for further addicts, or for the additional transplantation of the nerve.

Closely 1% of arrester arresters develop as a result of systemic angiitis from the results to the process of nirkovy vasodins. Prior to them, vuzlikovy periarteritis, Wegener's granulomatosis, gostra sclerodermic nirka are introduced into the first place. The development of these stan- dards is extremely important, as well as adequate immunosuppressive therapy for hemodialysis can lead to the renewal of the function of nirok.

It was also about a traumatic injury of nirkovy vessels, which is supervised by a hostile nirkovy deficiency. An external two-sided disruption of the nirkovy connection can pass through the vessels of power in case of an automobile accident, fall from the sky, etc. In case of a unilateral strike, tubular necrosis can develop in a non-malignant nerve.

Traumatic thrombosis of the nirkovo artery is also the most likely to be diagnosed in case of road accidents, but sometimes it can develop in the fall on the streets (Grablowsky O. et al., 1970], for one hour of thrombosis on sledges in grasses. The manifestation of nonfunctional nirka during internal urography with a normal picture during retrograde polygraphy allows to establish the correct diagnosis, which is confirmed by the data of aortography.

ed ed. EAT. Tareeva

In case of severe rejection and intoxication of nirka, you can become astonished with a development of toxic nephropathy. Only a little more quickly can help people to uncover an important acceleration of such manifestations - a nirk disadvantage.

toxic nephropathy

Due to toxic nephropathy, the reduction of parenchymal diseases, glomerular apparatus, as well as infusion of exogenous and endogenous toxic products and metabolites (code for MKH-10 - N14.4).

The classification of pathology includes the following types:

Specific nephropathy. It is tied with hospitable toxicoses, which can be diagnosed with rejection by small nephrotoxic rivers. Often, the deterioration of the function of the liver develops. Nonspecific nephropathy. Surrounded by the roslads of hemodynamics of the developmental ethology, provoked by the important detachments.

Causes and pathogenesis

Defeat nirok can be found through pathogenic infusion on the tissue of the very out-of-mouth speech, products in their fall, as well as on the development of autoimmune reactions.

Most of the time you get sick with the following words:

Important metal, їх salts; ethylene glycol; Shchavlev, otsic acid; Pesticides, herbicides; mish'yak; retailers; Midniy vitriol; Take away the twarin, coma; Toxins of mushrooms; Azotovmіsnі spoluki; Flying efіri; Inconsiderable alcohol.

Nephropathy is not very toxic to be restructuring in people who are busy with schoolyards, de robots are tied with grains, chemicals, rubber, polymers. Spend all the speeches in the body can be done through the organisation, so through the roof, through the shkira (in case of bites).

Some toxic nephropathy is affected by drugs - antibiotics, non-steroidal anti-pyretic drugs. Nonspecific lesion is possible in case of myoglobinuria, exotoxic shock, severe damage to the trophism of nirok in case of coma, depressed organs.

By pouring on toxins and metabolites on nyrcs, clitin parenchymal build-up, as well as the destruction of robotic glomeruli, which will wickle disease in the clitine psyche and lead to the precipitation of bilky fractions, is also stimulated. It’s like pouring hemotoxic otrups onto the organisms, stinking in parallel to the erythrocytes, as a result of which hemoglobin clogs the structural units of nirok - nephron. In some cases, there is a problem with nirok in the presence of aphids with strong amino acids. Yakim bi not buv pathogenesis, in the kintsevoy rakhunka, it is more sour hunger of tissue nirok, її ischemia, and without lіkuvannya lead to necrosis of tubules and glomeruli.

The severity of the damage of organs will be abundant in what type of speech it is, which is necessary for the organism, as it is, as a result of the way it is received. The main role of the development and health of the secular system to the detection of pathology - with the presence of chronic illnesses, nephropathy can develop in small doses of out-of-mouth speech.

Klinichna picture of nagaduє taku in case of glomerulonephritis. Some of the symptoms are lagging - weakness, robustness, galling, temperature may rise. The distance of the people is inevitably the swelling of the nig, the swelling of the individual. The indicators change in the warehouse of the slaughter - in the new growth there is a number of bricks, there is shelter (erythrocytes).

There are often signs of pathology:

Pidvischennya arterial grip right up to the highest digits. Change of dyuresu, frequency of sechovipuskan (inodi povna anuria). Pain across through the embankment nirok. Sudomi. Lower heart rate. Arrhythmia. Wheeze in legends.

Falling into the type of toxic speech before the described food key signs can be attached i specific symptoms... For example, if a person was destroyed by an overworldly number of sulfanilamides, then in case of toxic nephropathy, a new person has pain in the area of ​​loam, hemorrhage on the skin and mucus membranes, a hot camp.

Behind the steps of gravity, the differentiation is made in the following rank:

Persha - about the condition of the child, hemoglobin and erythrocytes in the blood, mild symptoms. Friend - duresis padaє, the amount of sečovina, calories, creatine in the blood is very growing, the symptoms grow. The third - in addition to a large number and a sharp decrease in the indicators of glomerular filtration of the potential development of a hostile deficiency - a mortally insecure acceleration.

In progressive nirkovo deficiency with toxic nephropathy, there are also several stages:

Initial (up to 3 days). Vidbuvatsya vlasne otrunnya organizm nephrotoxic agents. Oligoanuricheskaya (1-2 types). Through the closure of the line, the vision of the slaughter is reduced, so that the heart and the development of the nagging, zadishka, wheezing in the legends are brought up to the overwhelming. At the ts_th stage, the brain is also full of energy. Death is trapped in the form of breath with the build-up of legends, in the form of a heart, DIC syndrome. Often there is secondary vasculitis, anemia, thrombocytopenia. The stage of polyuria (up to decilky months and rocks). Such a stadiya insists for a friendly perebіgu ailments. Direz build-up, which can also lead to feverishness. Oduzhannya. All indicators of slaughter and robots will return to normal, moreover, it is not possible for all ailments to be renewed.

diagnostics

Call the diagnostics to be carried out at the same time at the official nephrology, where to bring the sick person at the age of adolescence at the hospital. Besides the characteristic clinical picture, I will respect the animal's history of pathology, and the spirited character of the disarray.

The methods of treatment for toxic nephropathy are as follows:

Zagalny analysis of blood, slaughter; Blood analysis for pH level, electrolytes; Biochemistry analysis of blood in the part of indicators of robots; Ultrasound nirok; If necessary - MRI nirok.

In case of nephropathy, the most frequent growth is SHOE, a number of leukocytes in the blood, anemia is caused. In the case of the growth, there are a number of blood cells, nitrogenous spoluks, there are hemoglobin and erythrocytes, cylinders. Pitoma of the blood is increased, and in the peripheral blood there is growth of creatine, sechovina, sechovic acid, and calories.

Frequently, toxic nephropathy is carried out in the form of emergency reanimation, especially in case of hospitality of nircovian deficiency. When there is less seriousness, the camp can go to the standard ward for the examination of nephrology (urology). It is necessary to repair a complex of visits for the therapy of ill health, but it is necessary to do it under the control of a toxicologist.

Naivazhlivіshim є come in on vivedennyu toxins, they will wipe out from the body. Tse reachable by way of following such priyomiv:

plasmapheresis; hemodialis; hemofiltration; hemosorption; Promivannya shlunkovo-intestinal tract.

Forsivaniy dіures zdіysnyuyut the introduction of eufіlіnu, mannitol, lasix. For promivannya slunk in the new to inject vaseline oil, or a large amount of ridini. Hemodialis of recommendations in the first 6 years of illness, for more than 48 years of treatment of the peritoneal dialis (purification of blood through the stalk).

Sorbents, glucocorticoids, as well as puddles are recommended for drugs in case of toxic nephropathy. Supplement the intake of glucose with vitamin C, insulin, sodium hydrogen carbonate, calcium chloride, vitamin C. If necessary, carry out transfusion of albumin and plasma.

Affection is easy to adapt to therapy, so as the structure of nirok is disgustingly updated, and the collapse of the nephrons can be seen in the early stages of the development of ailments. As a result, the indicators of robots will inevitably deteriorate. It is important for him to start therapy for himself. cob stage ailments.

Folding and forecast

The prognosis for toxic nephropathy lies in the type of branch speech and severity of ailments, the lethality is 20-70% in the fringes. Friendly prognosis only with the adequacy of therapy and freedom. The highest prognosis when cadmium, silicon, arsenate gets into the body.

The folding most often develops with a high concentration of toxins and is wiped off into the body, when it is victorious, not through the shorts, but through the roof. Hemolytic-uremic syndrome, interstitial nephritis, Gostra nirkova lack. It is not said to be accelerated to often lead to death through necrosis of some and all other functions.

Oleksandr Myasnikov in the program "About naygolovnish" raises about those who like to take care of them.

Toxic nephropathy is a disease, which can be found on aphids, in which children will be wiped off on the organism of people. I see an easy, medium and important form of ailment. Provokuvati development of the formation of nephropathy can be chronically ill (inflamed diabetics), if it is an infection.

General information about the disease

Nephropathy of a toxic type can be specific and nonspecific. In the first case, the ailment develops upon contact with the organism with grains, which are not unsuitable for nirk fabric. To bring to the development of the following words:

1. ocetic acid, mish'yakovy water, medium vitriol provoke blockage of nephrons with hemoglobin before the hour of ruinous erythrocytes;
2. mish'yak, mercury, lead, chromium, oxalic acid, ethylene glycol, if it gets into the body, repair the ruinuvati nirk tissue;
3. hepatorenal syndrome, which develops when the liver is deprived of the liver and is superfused with a wikid of amino acids, which causes the ear of the liver.

Nonspecific nephropathy manifests itself when the body is in contact with the scraps, but do not pour it directly onto the nirk tissue, or even produce it until it is finished. The stench can provoke a decrease in the arterial pressure, change in the electrolyte balance, muscle damage to the blood flow and not compensate for the change in the acid-puddle balance in a small change in pH. Okremo varto zgadati formulation of toxic nephropathy by eliminating compression injuries or tearing the tissue. Vona grows, if the nirk is in the overwhelmed camp and cannot vivoditi toxic speech, which is violated by the body.

Infectious toxic nephropathy appears on aphids of the GRZ, GDVI and others colds... Children are sick more often, not old enough, that is why the immune system of the body, but growth is more weak. Too much of the form of ailments are friendly and not in specific and therapeutic visits. In the world of infectious process nephropathy pass. I will increase the manifestation of ailments by 3-4 days.

Infections are taken through the inflow of the otrut, the product is in the drop of chemistry or autoimmune reactions, in the wickedness of the organisms. The step of the nirk tissue is to lay aside as many words have penetrated, the way it is consumed in the body and chemical warehouse. Another factor, which is infused into the branch of the zhvoryuvannya, is the mill of the sechostatic system. People with chronic pyelonephritis, ICD, nephroptosis, glomerulonephritis, it is more important to endure the infusion of branched speech on the nirkas. Nephropathy of a toxic type most often develops through:

1. unauthorized reception of drugs (anti-fumes, antibiotics);
2. penetration into the organism of salts of important metals;
3. contact with organic pesticides;
4. penetration of exogenous chemical spoluk (mushroom toxins, a bite of a tick or a coma, creature).

show ailments

Symptoms of malaise and malignancy and often lead to non-malignant deficiencies, as well as accelerating the diagnostic process. The first manifestation of the ailment is the change in the warehouse of the slaughter during the OAM. Bagato patients come to lykarns with nephropathies, scho vinykla through the priyom of lykarsky zasobiv. Intoxication to produce a specific autoimmune reaction. Show the following:

• p_advischennya arterial vise;
• bile in the lower part of the back;
• embellishments of kintzivok and denunciations;
• a change in the number of vivedos;
• the appearance of blood in the battle for protein;
• sudomi.

Falsely according to the type of drug, which has become the cause of the withdrawal, there may be specific signs of intoxication. Serious accelerated nephropathy є nirkov deficiency. As soon as you do not turn to lycarna, people can fall into a coma.

diagnostics

Detect the presence of ailments in the body allows biochemical and clinical analysis of blood. Dodatkovo for diagnostics, the following methods are used to diagnose:

• zagalny analysis of the slaughter;
• Ultrasound nirok;
• perevirka water balance organism;
• oblik dyuresu.

special features of therapy

Treatment of nephropathy is carried out in a hospital. If the patient is acting in a difficult camp, then he will be left in reanimation. The first stage of stabilization of the sick person is the introduction of toxin from the body. If the cause was an autoimmune reaction, then the corticosteroids are vicious to reduce the manifestation of allergies. Likar zdіysnyuyut come in:

• cleaning of blood through special filters;
• the introduction of proto-shock drugs;
• pryvannya shlunka (yaksho toxin after drinking it at once);
• connecting a sick person to the apparatus, scho the vicon the role of a piece nirka;
• accelerated by the path of the introduction to the patient of diuretics.

To a sick person they give sechoginny, puddle pitty, sorbent. For an hour moving to the stationary, it is necessary to take care of the post-regime. Products from a great number of bilka slid in a razionu. As the uremia is strongly reversed, the patient should be transferred to carbohydrate consumption. As far as the function is visible, it did not suffer, the ailing one is recognized as being pitty.

Likar run after the camp of the shkiri, so that through it there can be toxic products. As a result, the patients have a strong itch. It is recommended to take a shower or to wipe it off at least once for good. For an hour we are sick, we give salt to drink to reduce the amount of sodium chloride.

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In contact with

Toxic nephropathy is a pathological condition, which is characterized by tissue loss and deterioration of its functions as a result of the infusion of toxic words.

May be of great importance in the processes of biotransformation of large toxins. Nirks themselves take an active part in their metabolism and elimination of the body. We will help you with the filtering, secretion and excretion of functions of foldable transfer systems. Nirki vivoditi vivoditi nerazchinni in the water of chemical speech, at the same concentration in the structures of the given organ, it transmutes so in syrovatz blood.

The fate of nirok in the processes of introducing toxins into the pathway for trivial contact with cimi speech, which promotes the development of nephropathy.

Causes of the blame

Whether exogenous speeches of chemical or biological nature can be victorious in the battle. However, the deyakі from them may have a special path to nirk fabrics and more often for those who negatively infuse nirk structures. The stench was called “nephrotoxic speech”. Among them, the most often in the role of nephrotoxic factors are:

• medications for drugs (antibiotics, і sulfanilamіdnі drugs, protisudomіnі, cytostatics);
• X-ray contrast speech;
• Revision of the concentration of speeches, which can be seen in the body of people in the physiological minds (sečovaya acid, kaliy, calcium);
• half of important metals (lead, mish'yak, mercury, cadmium, beryl, bismuth and in.);
• chemistry, how to be vicious to fight with schoolchildren and roselin ailments (half phosphorus, chlorinated in carbohydrates);
• organic products (tetrachlorethylene, methanol, tetrachloromethane);
• glycols;
• hemolysis and in.

Mechanisms for the development of toxic nephropathy can be developed by:

• bezposredn high school for a lot of its high toxicity;
• negative inflow into the change of permissible concentrations;
• allergic reactions.

The nature of the steps of the development of the body is not only due to the chemical warehouse of the toxin and its concentration, but also to the specific body. Nirki, in which there is already a very pathological process, it is more important to endure the inflow of toxic substances in small concentrations.

how to manifest

Clinically manifest toxic nephropathy and malignancy. Most often it is very easy to overcome the form of ailments with laboratory tests (and blocks in the section). However, with a trivial injection of high concentrations of toxins, or with a decrease in the reactivity of the body and the presence of background discomfort, it can be important and irreversible.

I especially respect the slid of lykarsky nephropathies, as the broadening of them with skin rock grows. On the basis of some of the other types of toxic lesions in patients with lykar nephropathy, there is not only a toxic component, but rather an allergic reaction. At the connection with clear blood rushes, there may be a severe interruption in the battle court system and interstitium.

Likarski urazhennya nirok can manifest itself:

• guest house;
• nephrotic syndrome;
• tubulointerstitial nephritis (i);
• transgranular fibrosis;
• Illuminate.

Hostry lykarskiy glomerulonephritis often develops on the back of the onset of allergies and may be slowed down by the overload of syrovatous ailments. Name the fault to manifest itself in one of the onset syndromes:

• nephrotic (massive proteinuria, nabryaki, lowering the level of blood sugar and albumin in the blood, hypercholesterolemia);
• (Hematuria, proteinuria, arterial hypertension, embryos).

Admission to glomerulonephritis with arthralgia, important lesions of the shkiri, high temperature is characteristic of sulfanilamide nephropathy. The basis of the pathology is the necrotizing reduction of other nirkovy vessels.

The important form of toxic damage to nirok with a gross nirk deficiency can be summed up:

• we host tubular necrosis;
• bilateral cortical necrosis;
• we will host the tubulointerstitia;
• hemoliticouremic syndrome;

Gostrium tubular necrosis does not develop very often as a result of the introduction into the body during diagnostic procedures of X-ray contrast (urographin, verographin), as it remains in the necrotic tubules, setting up the procedures for the procedure. Take a tsomu:

• the introduction of large doses of contrast;
• reduction of filtering health on the basis of heart failure, red diabetes;
• carrying out the doslіdzhennya on tlі hot events.

Also, nirok exercise is characterized by quick growths of uremia and uncomfortable prognosis.

Likewise, tubular nephrosis can be used as a reaction to aminoglycoside antibiotics. It is not easy to get lost due to decreased hearing (due to ototoxicity) and to manifest:

• oliguria (change in the number of slashes);
• Decreases in the efficiency of the slaughter;
• small protein and hematuria.

One of the most common reasons for the development of a hostile nirkova deficiency in lykarsky diseases is a tubulointerstitial nephritis. It is characteristic of the new one:

• stupid bill at dilyantsi nirok;
• the improvement of the dobovy kilkosti sich;
• slaughter siege (appearance of blood cells and leukocytes);
• early deterioration of the function of azotemia without oliguria.

Before children, accelerated lykarskoy nephropathy is diagnosed with bilateral cortical necrosis. It’s a very important break and show itself in a classy way:

• oliguria;
• to give birth to products of nitrogenous exchange in the blood;
• feverish;
• Intense pain across;
• to a large number of images of a blood cell and blood cells from a cross section.

Hemolytic-uremic syndrome of accelerated therapy with cytostatics. The main key manifestations of this pathology can be:

• progressing uremia.

Hepato-renal syndrome often develops on aphthae of non-steroidal anti-epidurals. Vidminnoy special given pathology є preserving the concentration of the function of nirok in case of a sharp decrease in health to filtration. Typical signs of a tsyo zhvoryuvannya є:

• a change in the dobovy count;
• pechinkovo-klinna lack;
• rapidly growing azotemia.

When the nephrotoxic spits are removed from the sick person, a picture of hostile deficiency develops on the basis of symptoms of extra toxicity and toxic intestinal damage.

Basics of diagnosis and treatment

Diagnostics of toxic nephropathies In order to make a correct diagnosis, it is necessary to provide clinical and laboratory data, as well as to reveal a toxic infusion in the anamnesis. The planning plan in such categories includes:

• ultrasound doslіdzhennya nirok;
• in folding vipad -.

The main principle of the treatment of toxic lesions is nyrok - weakening of the cause, and the very principle of the treatment of toxic speech and vivenation of the organism. The tactics of the management of the ailments should be based on the nature of the pathological changes.

• Methods are used for elimination of the antigen.
• In case of gross urazhennye glomeruli or interstitial tissue, corticosteroids are recognized.
• When hemolytic-uremic syndrome is stagnant

Nephropathy is a two-fold problem of nirok, as it can be due to other reasons. Zokrema, toxic nephropathy is established as a result of the infusion of oranges. They are good, including the filtration of blood, the most intense and irrelevant words, as they go to the body through the cross. In such a rank, the tribute of speech is often accumulated in nirk structures, and if the concentration in the blood is promoted, then the purchase will be significant.

Mechanism of afflicting ailments

Looking at the functional features of nirok, the regularity of the development of toxic nephropathy can be represented by such a rank. When people get into the organism of a person, they can be drawn without a second or a second, injecting internal organs into the robot, including nirok. As a result, the structure will collapse, the robot will collapse, a pathological stump, and will be supervised by singular symptoms.

According to the straightness of the negative injection, and apparently, behind the mechanism of education, toxic nephropathy extends to specific and nonspecific. The first person will see a problem without the middle of the lines themselves, without the middle as a result of the battle with different words. The other one - nirku will use the rods through the otrunnya organizmu, but don’t put a direct infusion on the nirkas, but such as to destroy the robot of the other organs and their systems, so, in his own devil, to produce even before the fight nirok.

By means of the mechanism of development of nonspecific toxic nephropathy, the following processes can be used:

There are several reasons for this directly. Up to the number of factors that a pathological stance is given, negative phenomena are recognized, for example:

Viciousness in Danish nirkah process can and іnshі reasons, for example, radioactivity, mechanical injuries, damage by an electric strum. With the recognition of lіkuvannya, the main meaning is the character of the fight. Have a vipadku, a subtle camp of vimag of non-blatant medical visits.

Lyudin, who has taken into account whether there are some overwhelming factors, for the purpose of a more reliable hospitalization for the purpose of the step and character of the step, as well as coming in for the purpose of neutralization.

symptoms of ailment

If I show a pathological stance, it’s just like the first legacy, I’ll lie down in the first step of the step of this gravity, which there are three - easy, middle and important. The purpose of the step is to lay aside the strength / triviality in the inflow of a negative factor, the nature of the spout and concentration in the blood. Toxic nephropathy is susceptible to superficial symptoms:

In the skin surrounding, the symptomatic picture may change, depending on the nature of the defect and the degree of its severity. In some cases, there is a possibility of spostering damage from the side of the central nervous system, manifesting hallucinations, swelling psychoses.

People in this country often have signs of anemia. The temperature may change, in other words, the camp is characterized by the manifestation of signs of intoxication to the body.

In addition to obvious manifestations, there are signs of a test, which appear in the course of laboratory tests and diagnostic procedures. The patient in the whole country is recognized:

• zagalny blood analysis;
• zagalny analysis of the slaughter;
• dopplerography;
• biochemical analysis and in.

As a result of the follow-up of the patient with toxic nephropathy, changes appear in the warehouses of the blood and blood, and the appearance of hostile speech, concentration, structural and functional changes, etc. In this case, it can grow in place of blood, blood, changes in the parameters. In the blood, the concentration of nitrogenous bases grows. All symptoms can be established only in the process of professional diagnostics in the minds of a medical mortgage.

Likuvannya and forecast

The slid of the nobility, the nephropathy of the toxic form, is a rather unfavorable camp.

Important! In any case, it is not possible to rob a self-directed abuse, and also to drag out the animals to the drug.

Likuvannya, as it will be necessary in the skin condition, to lay down on the main parameters of the pathological process, such as the steps of its severity, character, etc. In the first place of patients, antidote therapy is indicated, in addition, stimulation of the slaughter, and procedures for cleansing the blood are carried out. The transfer of procedures into a wide range can be as follows:

• hemodialis;
• plasmapheresis;
• hemofiltration;
• washing of the shlunka and ін.

In addition, in the presence of a patient, in the presence of a patient, he may have undergone a proto-shock therapy, as well as procedures that were directed to the restoration of homeostasis.

As soon as the patient is qualified, I will help in the first year of writing, to bring a toxin from the body, it is possible to unify the most important inheritances. The hostile speech will not be awakened by the memory of the most skoda.

In the іnshomu vipad, the blood is removed from the body, the blood is purified, etc. There will be a need to update the function of the affected organ, which may have problems with nirkami, for example, it can take a risk or more.

The prognosis for the development of ill health can also be found in a number of minds and in the first place - on the stage of this gravity:

As soon as there is a sense of damage to the body, one of the possible methods described earlier, then immediately turns up to the medical plant, without any signs of symptoms. In the whole vipadku it is possible to get rid of internal organs, or to bring him to the minimum.

mid many heritage, Up to some in a number of vipads, produce toxic nephropathy, it is possible to see:

• new establishment of the secular nobles;
• Gostra and chronic nirkova lack;
• swelling of the brain;
• pack of legends;
• coma;
• lethal result.

Brutal respect! While the inheritance is considered to be extremely important, it is even more important for you to turn up for help before the liquor and start before the treatment.

In the course of the experience, they describe not only their statuses, but the furnishings, which they brought before, the hour and the way of the detachment (battle).

vsepropechen.ru

toxic nephropathy is one of the most widespread in the case of exogenous exogenous abnormalities of pathological syndromes.

The exotoxic nature of nephropathy is indicated in an hour in 18-20% of the ailments with a hostile nirkovo deficiency (GNN), which is found on lykuvanny in the modern “nirk centers”. At the same time, two main types of exotoxic damage appear: they are specific, they are not very sensitive to a number of nephrotropic chemical reactions in a number of nephrotropic chemical reactions, and they are not specific.

Specific battle nirok They win in Pershuvaya Cherga when they are treated with nephrotoxic speech, but when they are "active transport" It is unimportant in the sense of the intimate mechanism of nephrotoxic speech, the sum total result of the same thing: it is not important to increase the accumulation of cych spores in nyrkas to produce small changes in enzymatic-metabolic functions and their reduction.

When infused on the organism of hemolytic speech in nirkas, a pathomorphological picture of a severe hemoglobinuric nephrosis develops. Pathomorphological data visualize the transport of blood to hemoglobin in the brain of internal vascular hemolysis and exotoxic shock.

Vilny hemoglobin of the plasm is absorbed in the zone of chemical degradation of tissue degradation products and swells the character of an alien protein, causing an immune reaction to the organism. This reaction is manifested by a spasm of nirkovy vessels, a decrease in deuresis, an increase in temperature and other signs of the so-called endogenous toxicosis in case of toxic etiology.

Great mice in the pathogenesis of toxic nephropathy in patients with hospitality Loan "miorenal syndrome", which is a kind of uncommon kind of syndrome of trivial crush syndrome (Crush-syndrome). The whole syndrome develops as a result of the combined infusion on the organism of the growth factors, the most infusion of the food from the most toxic substances of the narcotic drug (oxides, alcohol and surrogates, sodas and alcohol) trivialy press M'yakh fabrics, most often m'yaz_v kintzivok. Ailments lie on a hard surface, as a rule, on a boat, sometimes in a position to sit, because of the laid-ups. "Morenal syndrome" can cause overwhelming coma, exotoxic shock, deterioration of the outbreak, coldness.

In case of pathomorphological preliminaries, the appearance of ischemic coagulation necrosis of the muscular tissue ("rhabdomyolis") in the zones of local positional health develops, a small swelling of the tissue develops. In nirkahs, a picture of a severe pigmented nephrosis is indicated, characteristic rice which is the manifestation of myoglobin in the enlightenment of the nephron and in the epithelium of vivid tubules. Myoglobin was consumed in the shelter from necrotic dalyanoks of urazhennyh m'yaziv.

In the pathogenesis of "miorenal syndrome", it is of great importance to suck a trivial spasm of the cortical ball of the nerve and the development of shuntuvatisya juxtamedullary blood circulation. It is not possible to vklyuchiti pituitary injected develops in the nirkah of the malformations of the internal vascular laryngeal larynx due to the infusion of thromboplastic factors, so that myolysis occurs in the presence of myolysis, as well as an intravenous type of toxin, which causes its own type of toxin.

In the pathogenesis of toxic lesions of nirok in case of gostrich dents with hepatotoxic streams(CC14, mushroom toxins and in.) Significant, mabut, low nephrotoxic action of certain amino acids (leucine, tyrosine and in.) Pathomorphological data in case of a pathology of the same type and a picture of diffuse cholemic nephrosis. Sign of necronephrosis

Nonspecific urazhennya nirok exotoxic.
nephritis, nephro-sclerosis і ін.).

Clinical characteristics of toxic nephropathy transferring the need for a total assessment of the main clinical and laboratory indicators of the functional standard of nirok. Before the strongest symptomatology of toxic toxicity in the toxicogenic phase, the state of the art is associated with a decrease in the amount of urinary output, for example, in the case of the disease, it is associated with the growing interstitiality with a wide range of The most common picture of toxic nephropathy begins to appear in the somatogenic phase during the development of hostile nephropathy.

The main respect in early diagnosis toxic nephropathy is associated with a "cut syndrome" in case of retinal vimiri dyuresis with urahuvannya carried out by a sick person infusion therapy and you can trash the line in a late way. Vvazhaєya, how to reduce the diuresis to 500 ml for dobu (20 ml / year, 0.35 ml / hv), for the development of oliguria, and up to 100 ml for dobu (4-5 ml / year, 0.07 ml / min) - anuria.

One of the simplest indicators of the concentration of health is the level of strength of the section, which is important to progress with glucose and protein. With a single 1% glucose, the indicator shifts by 0.0037, and 1% glucose - by 0.0026. Most of the high numbers of serum (up to 1024-1052) and protein (up to 330%) are prevented in case of toxic nephropathy, vicyclic and other hemolytic discourses, for example, osteocentesis, and severe prognosis. The stage of proteineuria in case of a whole increase in the degree of hemoglobinuria. An excellent test of the functional standard of nirok є azotemia, as well as the concentration index of the section (the ratio of the concentration of the section to the section of blood). Decrease of the index to 10 and lower depends on the turn of the deterioration of the function of nirok.

Suchasnі way to vivchennya funktsіonalnogo will nirok vklyuchayut vimіr osmolality vise plasma i sechі freezing point depression method vivchennya vzaєmin elektrolіtnogo warehouse plasma krovі i sechі, KHS, vimіr klubochkovoїfіltratsії i kanaltsevoї reabsorbtsії for Relief Proby Rehberg - Tareeva, vimіr nirkovogo plasma flow by Smіta, toksikologіchnі doslіdzhennya on viznachennyu klіrensu toxic fluids, except for calorimetric values ​​of hemoglobin in blood plasma and blood plasma, as well as methods of radioisotope diagnostics of damage to normal functions.

Three degrees of severity of toxic nephropathy have been seen. Toxic nephropathy of the lung step, as it develops in about 25% of the development of the defect of the function of nirok in case of young children xv) і nirk plasma flow (582.2Hz 13.6 ml / hv) while saving concentration and nitrogen-visual function of nirok.

Toxic nephropathy of the middle stage, as it develops in approximately 57% of cases of this pathology, appears to be more vivid and strong changes in the typical and morphological warehouse of the section (up to 2-3 females). ), tubular reabsorption (98.2 + 0.1%) і Nirc plasma flow (468.7 ± 20.2 ml / min).

For toxic nephropathy of a severe stage, the characteristic syndrome of hostile deficiency, which means about 10% of cases of this pathology, with manifestations of oliguria, azotemia, creatinemia, small tuberculosis 88, 9 ± 1.8%), significant reductions in Nirk plasma flow (131.6 ± 14.4 ml / hv).

Gostra nirkova lack in gostrich hospitality be important key interruption as a result squabble liver (toxic hepatopathy - 82% of cases) and lungs (toxic pneumonia - 36.6% of cases), which increases the high mortality rate, reaching 50%.

Slid vrahovuvati, when you are disabled in a group of important ailments with toxic nephropathy and hepatopathy, you will become more susceptible to the syndrome of nirkovo-hepatic insufficiency (AKI). As a result of a single improvement of the liver, it will intervene together to compensate for the inflow of the functions of the important organs. Moreover, as a result of the appearance of nephrotoxicity in a number of chemical words, as well as the manifestations of toxic hepatopathy, and hepatotoxicity of chemical words, which disrupts the function of nirok. It is especially important to introduce a hundred changes in the clinical symptomatology and dynamics of laboratory data in the event of a non-toxic deficiency of exotoxic ethology.

In the classic picture of hospitality, there are 4 main periods:

• 1) the period of the cob stage of the main ethiological factor;
• 2) the period of oligoanuria;
• 3) the period of renewal of the renewal;
• 4) period of use.

In case of hospitality, the period of the cob ear, when the ear of the factor is triggered, is caused by the toxicogenic phase of the disease due to the power of the given toxic speech by the clinical symptomatology.

In the period of oligoanuria, which is close to 2 types, the picture of endogenous uremic toxicity develops, as a result of the inherited blockade of glomerular fibrillation due to the formation of a metabolic disease However, without affection for an important clinical camp, the azotemia will be too lazy (dose-4 g / l) to explain the lowering of the process of making a severance in a bit of trouble. Gradually appear in the whole period of the state of the world, a lack of water-electrolyte exchange, when some calories go from the cells to the roof, and some of them are substituted for those who need to develop. The whole process is explained by the non-triviality of the rivovagi, the lingering between the high internal and low concentrations of calories, in order to produce vitrates for the oxidative energy of the cells of the cells In case of hospitality, which is often supervised by a decrease in oxidative-primary processes in cells and an increase in the penetration of cell membranes, the loss of internal calyx is inevitable. With the symptoms of oligoanuria, as a result of the continuous deficiency of calories, hypercaloria may cause symptoms of caloric toxicity (deterioration of the heart and nerves).

A very high stage of hypercalculation is more likely to be observed in case of hospitalization, which causes hemolysis or myolysis due to the intensive flow of calories from the cells into the plasma.

At the period of renewal of duresis, or with large losses of calories through shlunkovo-intestinal tract winyk hipokalієmiya, as it is clinically provocative to manifest itself with nonspecific symptoms of internal malformations - meat weakness, lean.

The stage of the first electrical dissociation is based on the level of natural efficiency of the given electrolyte. Chim vishche tsei klirens, tim more intensive accumulation during anuria and a large increase in the increase in the concentration of standards.

Without concern for those who have oligoanuria, the effect of all electrolytes has been destroyed, and the concentration in the plasma is increased to deprive those of them. The price is tied to the development of the hyperhydration of the body during the whole period of the state of health and deficiency, if the process of accumulation of water is more efficient, the process of accumulation of words with low clarity (sodium, chlorine, calcium water) is reduced. For those who are in the polyurethane phase, if they consume water and inject salts, the concentration of sodium, chlorine and calcium will return to normal. In addition to the mechanics of breeding, the process of transferring the ions from the back space in the clitine is very fast.

Hyperhydration of the body in the case of a lack of toxicity of the liver of a toxic liver disease is not only long-term anuria, but also by transudation of bilky plasmas into the intermediate tissue in connection with the appearance of such a penetration At the same time, the osmotic grip of plasmas quickly falls, there is a swelling and swelling of blood, which accumulates important changes in the brain and legends with the development of neuropsychiatric disorders and breakdowns of the emotional state. The rest of the most often manifested by the syndrome of "vologic lungs", which is a developmental stage of the growth of the leg tissue.

The change in the legends tends to give rise to a revolving development in case of renewed dehydration and reduction of hyperhydration, to serve as friendly children for the diagnosis of pneumonia, differential diagnosis in the case of deficiencies. A permanent companion of the hostile deficiency of toxic etiology є anemia, which is of a zalizodeficit character and is tied to the damage of eritropoiesis. The destruction of the outbreak and the anemia will significantly contribute to the tissue hypoxia, unfriendly mind for the regeneration of the nirk-like diet and the renewal of the nirk functions, which are promoted not earlier than 30-35 dib for the development of important toxic nephropathy. Especially Dovgy protіkaє vіdnovlennya nirkovih funktsіy at GOSTR otruєnnyah otstovoyu esentsієyu, if azotovidіlnoї kontsentratsіyna zdatnіst nirok povnіstyu normalіzuєtsya tіlki pid kіnets 6th mіsyatsya pіslya zahvoryuvannya cob, and when vazhkіy nefropatії, viklikanoї otruєnnyam etilenglіkolem, podіbne vіdnovlennya funktsіy Je great rіdkіstyu.

best often the reason toxic nephropathy є

Luzhnikiv Є. A. Clinical toxicology, 1982

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Reasons for the diagnosis of pathology

Pathology is given to develop through:

• toxic to the infusion of hair, not the ostruinnyh ryechovins themselves, as well as products їх rozpadu;
• vinnennya in the midst of an autoimmune reaction to the body.

At the same time, the development of toxic nirka is unaffected by the start-up mechanism, її cleverly show add me to myself. The step is to lay it down in the form of a concentration of toxic speech, which is chemically stored and the way it is appropriate in the body. Equally important is the role of the development of secular organs. So, even if there are pathological processes in nirkahs, toxic nephropathy can develop with appropriate low doses of branched words.

Until the end of the day, in principle, I can lead, be it a hit of chemistry and biological words, ale nybilsh is often more toxic.

• organic retail managers;
• salts of important metals;
• pesticides;
• different drugs (antibiotics of the aminoglycoside series, sulfanilamides, non-steroidal antiapaline drugs, anticoagulants, etc.);
• physical inflow (exchange of ailments, injury with an electric strum, injuries);
• Exogenous chemical spoluks (words that come into the bloodstream when bitten by bran and comas, fungus toxins, etc.).

It is possible to mention that nephropathy is toxic - a foldable polyethiological discomfort, so it is necessary to clearly identify the key symptoms of a possible factor, and they have led to development, and in the case of consuming inaccurately conduct antidote therapy.

symptoms

Most often, it is manifested by changes in the backward analysis of the slaughter, such as protein and hematuria. The stench is fast to pass, and the people do not know that they just didn’t know what they were saying. If the dose and concentration is too high, then it can lead to heavy, non-backward herd.

In the midst of more toxic nephropathies, the left part of the loan is taken care of by drug problems, with a large inflow of chemical agents, the macroorganism is affected by the immune reactions. The price is tied with this, that the fabrics are nyrok including widely spread sudinn hem, and all the allergic components (ogryadnі clіtini, interleukini, immunoglobulin), in the heat of the battle, in the process of suppressing.

Symptoms of lykarsky nephropathies are similar to signs of glomerulonephritis, if ailments are seen zagalne nezduzhannya, Weakness, gratitude. Nyogo has some quirks lower kintzivok and individuals. In the case of a growth, hematuria and proteinuria. The frequency and number of sechovipuskan (oligoanuria) also decrease. Another important and dangerous symptom next to the appearance of arterial hypertension, as it is possible to reach absolutely other numbers, are vicious in people, and they will be attacked by the court and zupinki of the heart are fast.

In case of toxic infusion of sulfanilamide drugs, which are representatives of such є streptocide and norsulfazole, before the gastrointestinal symptoms, a fever is a sign of strong pain in the slopes, the reduction of the shkіri and mucous membranes in the viglyadі hemorrhagic visipans. On the level of nirk capillaries, it is possible to improve the importance of the endothelium of the cichus of the Sudin, from the vigorous stages and to the development of the Court's penetration.

Folding and methods of treatment

Most often toxic nephropathy can lead to the development of interstitial nephritis, hemolytic-uremic syndrome and hostile deficiency. Jade is manifested by the guest abo dumb sick across, chills, short-hour shifts in arterial vise, arthralgia (pain in the slopes) and changes in the slit (polyuria, microhematuria, decreased glomerular filtration).

In the analysis of the blood, the most frequent occurrence is the development of the SHOE, the concomitant leukocytosis and the anemia. Gostra nirkova lack of - tse is already a threat, most often to produce a lethal result. Vona is pummeled with rapid reductions, or increased vipadinnya function nirok and manifested in a standard set key symptoms: Oligoanuria, absorbing nitrogenous slags in the organisms, deteriorating the water-electrolyte balance and acid-puddle stun. The head acquaintance will become involved in the necrosis of the cortical ball of nirok, which can lead to non-gated weeds.

All options for toxic nephropathy can be easily treated. Naybilsh important yogo warehouse track to respect antidote therapy on the cob stages of becoming ill. If it’s not carried out, the drug users will be deprived of carrying out symptomatic and disintoxicating therapy. So, when banned with sulfanilamides, prescribe a puddle of pitta, sechogin, drugs that block carbonic anhydrase.

In case of gross glomerulonephritis and interstitial nephritis, a large dose of glucocorticosteroids is indicated, but it should be done with a forced anti-apical action.

Plasmapheresis and hemodialysis should be carried out using the method of improving the organism of products in the drop and surplus of high-grade fluids. The essence of such manipulation of the field is in the fact that before a sick person is connected a special apparatus, which is selected from a new blood port, through a system of filters and already purified, it is turned back into the body.

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symptomatology

Dane became ill, taken to the level of gravity. Symptoms of toxic nephropathy of the early stages may be of their own specificity.

1. Easy foot. The ear itself is sick, about how there can be a signal to get rid of white ravines in urine, and also appeared in my shelter.
2. middle step... Before pererakhovanih vische signs are added to the decrease in deiuresis, increase in sechovina, calia and creatine.
3. important feet... Zanedbaniy stan, before the hour of development of the state standard of nirkova lack.

Div. also:

• Learn more about the signs of nephropathy of the first species.

At the early stages of infectious toxic nephropathy, it manifests itself as a decrease in duresis, right up to the onset of oliguria and anuria. Analyze to show the value of urini to 1052. Azotemia and a decrease in glomerular filtration, as well as tubular reabsorption, are indicated. Patients fix to show scars on the cross-section of the pain. Vidbuvatsya tse through the build-up of the interstitial nabrya nirok. There are reasons for the appearance and puffiness of an individual.

The name of the hospitality industry is characterized by higher and higher quality. Whenever, in the organs of the morphological changes(As a result of dystrophy, the main reason for the decrease is clitin). The stages of these processes lie in the form of doses and types of removed toxins.

With a lot of detachment, as they are chronic in nature, they become plethora. Om the power of diffuse leukocyte infiltration, manifest an extra capillary intrate, enlargement of the empty glomerular capsule. Likewise, the order of the lesions of the tubules and glomeruli and interstitial changes, as a result of such patients, is overwhelmed, argiophilic fibers of the stroma coarse. Nephrosclerotic lesions are not included.

Toxic nephropathy in children also develops through toxins entering the body. Show it - also for yourself, for grown-ups. Such children are constantly guilty of being tested by the doctor, passing and prophylactic treatment.

therapy

If you are susceptible to toxic damage to your organisms, you will inadvertently turn up to a toxicologist. And with the appearance of symptoms of toxic nephropathy, it is innocuous to get sick.

Diagnostics come in and start building up to the folding of the classic picture. It is so important and respectful to sponsor the direz. There is no small significance in laboratory control over the urine mill (especially, for the acid-puddle storage, electrolytes in the blood and indicators of nitrogen metabolism).

Diagnostics of the soil is based on the key pictures, guarded by the diuresis and on the given laboratory tests (acid-pool, electrolyte plasmas, indicators of nitrogen exchange).

The first therapeutic stage of the field in the passage of the ethological treatment, as often for all the primed on the prophylactic visit. Such therapy is very good sense and yes, good results are only for saving the clockwork for medical assistance, and for carrying out the treatment already in the first year of the ingestion of toxins in the body.

Navіvazhі vyvazhі vypadki ostrunnya, for example, with dichlorethane, can end with a positive result, as well as reports zusil on shvidku vivedennyu wipe out the organism. At the same time, the picture is more friendly, as it is not seen the defeat of the liver.

As soon as the otruunnya became hepatotoxic speech, a complex of drug entry stagnated, which was straightened to the vivedennya from the organism. At the same time, pershochergovo slid in the slurry, add an adsorbent (active vugilla) to the new vaseline oil. For the first six years, it was recommended to carry out hemodialysis, with a stretch of two dib - peritoneal dialysis.

Predictions for the farther distance are even more agreeable, ale only for the mind, which was recognized at the earliest stages and was carried out adequately and not admittedly by the patient. In addition, in the general order, it should be possible to avoid contact with toxins. Do not expect the prognosis of nephropathy, which has developed as a result of the infusion of silicon, arsenate and cadmium.

professional come in polyagaє in pershu chergu in the customary hygienic norms of pratsi.

Pathology of nirok, lesion of the glomerular apparatus and tissue nirok, provoked in the introduction into the organism of nephrotoxic sprains (code for MKH-10 - N14.4) or accumulated.

I see the steps of gravity overcoming the ailment:

• light - insignificant symptomatology, change of laboratory indicators in blood and section;
• middle - a decrease in deuresis, an increase in uremia and symptoms;
• important is the reduction of glomerular filtration, development of the growth, the ability to accelerate the lack of nirk.

A number of ailments and factors can lead to nephropathy, for example, diabetic diabetes, which can also be of infectious-toxic genesis.

Causes and pathogenesis

Defeat nirok can be found through pathogenic infusion on the tissue of the very out-of-mouth speech, products in their fall, as well as on the development of autoimmune reactions.

Most of the time you get sick with the following words:

• Important metal, їх salts;
• ethylene glycol;
• Shchavlev, otsic acid;
• Pesticides, herbicides;
• mish'yak;
• retailers;
• Midniy vitriol;
• Take away the twarin, coma;
• Toxins of mushrooms;
• Azotovmіsnі spoluki;
• Flying efіri;
• Inconsiderable alcohol.

Nephropathy is not very toxic to be restructuring in people who are busy with schoolyards, de robots are tied with grains, chemicals, rubber, polymers. Spend all the speeches in the body can be done through the organisation, so through the roof, through the shkira (in case of bites).

By pouring on toxins and metabolites on nyrcs, clitin parenchymal build-up, as well as the destruction of robotic glomeruli, which will wickle disease in the clitine psyche and lead to the precipitation of bilky fractions, is also stimulated. It’s like pouring hemotoxic otrups onto the organisms, stinking in parallel to the erythrocytes, as a result of which hemoglobin clogs the structural units of nirok - nephron.

The severity of the damage of organs will be abundant in what type of speech it is, which is necessary for the organism, as it is, as a result of the way it is received. The main role of the development and health of the secular system to the detection of pathology - with the presence of chronic illnesses, nephropathy can develop in small doses of out-of-mouth speech.

Klinichna picture of nagaduє taku in case of glomerulonephritis. Some of the symptoms are lagging - weakness, robustness, galling, temperature may rise. The distance of the people is inevitably the swelling of the nig, the swelling of the individual. The indicators change in the warehouse of the slaughter - in the new growth there is a number of bricks, there is shelter (erythrocytes).

There are often signs of pathology:

• Pidvischennya arterial grip right up to the highest digits.
• Change of dyuresu, frequency of sechovipuskan (inodi povna anuria).
• Pain across through the embankment nirok.
• Sudomi.
• Lower heart rate.
• Arrhythmia.
• Wheeze in legends.

Falling into the type of toxic speech, before those described by the main signs, there may be specific symptoms. For example, if a person was destroyed by an overworldly number of sulfanilamides, then in case of toxic nephropathy, a new person has pain in the area of ​​loam, hemorrhage on the skin and mucus membranes, a hot camp.

Behind the steps of gravity, the differentiation is made in the following rank:

1. Persha - about the condition of the child, hemoglobin and erythrocytes in the blood, mild symptoms.
2. Friend - duresis padaє, the amount of sečovina, calories, creatine in the blood is very growing, the symptoms grow.
3. The third - in addition to a large number and a sharp decrease in the indicators of glomerular filtration of the potential development of a hostile deficiency - a mortally insecure acceleration.

In progressive nirkovo deficiency with toxic nephropathy, there are also several stages:

1. Initial (up to 3 days). Vidbuvatsya vlasne otrunnya organizm nephrotoxic agents.
2. Oligoanuricheskaya (1-2 types). Through the closure of the line, the vision of the slaughter is reduced, so that the heart and the development of the nagging, zadishka, wheezing in the legends are brought up to the overwhelming. At the ts_th stage, the brain is also full of energy. Death is trapped in the form of breath with the build-up of legends, in the form of a heart, DIC syndrome. Often there is secondary vasculitis, anemia, thrombocytopenia.
3. The stage of polyuria (up to decilky months and rocks). Such a stadiya insists for a friendly perebіgu ailments. Direz build-up, which can also lead to feverishness.
4. Oduzhannya. All indicators of slaughter and robots will return to normal, moreover, it is not possible for all ailments to be renewed.

Main causes and prolonged toxic nephropathy

Yak with mushrooms, substitutes for alcohol, or sprinkles, so that the time of the fall of the organisms' tissues, head problem for nirok є negative injection of toxins on the internal nirk structure. It is the most total destruction of robots to produce nirok that is not safe for life and health.

Toxic nephropathy in a large number of evolving vapors develops to be consumed in the organism of a singing group of chemically challenged spoluks, to them it is known:

• Lead, mercury;
• Azotovmіsnі spoluks - amіak, anіlіn, nitrobenzene;
• Halogenpohidnykh - chotirychloride in coal;
• Glycols - diethylene glycol, antifreeze;
• Efiri - ethyl acrylate, dioxane.

Lead to the development of the disease can be consumed in the organism of the meadow, acids, insecticides in the increased concentration. Pathology occurs most often in people who have special features without being tied to a robot with reinsured chemical words. It is more toxic for nirok infestation when weathered with strongly bran mushrooms, unkind foods, high doses of alcohol.

Nirki is a whole boy organ, similar in shape to kvassol, like a vicon of such functions:

• regulate the balance of life in the body;
• control and adapt to the correct arterial vise;
• to take part in the process of establishing blood children;
• vivodat products metabolism to the body.

Skin from nirok is stored from powerless nephrons - the whole special part of filtration. The skin from the nephrons is stored in the glomerulus of other blood-bearing vessels, the stench is semi-impermeable, so that through the membrane, the products of metabolism pass through them. Good products are displayed and exchanged at once from the cross-section.

As soon as the speeches penetrate into the organism, then all the attacks fall on the nephrons, which are repaired to disgustingly cope with their function. It’s a clear picture that it’s beyond the middle of the fact that the otruynaya speech penetrated the body.

Prior to the reasons for the diagnosis of toxic nephropathy, the following factors can be mentioned:

• otrunnya unpleasant alcoholic beverages;
• detachment with important metals;
• eating into the organism of young people;
• іntoksikatsіya, viclikana pesticides;
• overdosing on drugs, as well as overdosing with stitched or inaccurate drugs.

As soon as there is a lack of grudge, then it is possible to develop ischemia, like to get involved in a werewolf camp. If ischemia is a trivial hour not to catch up, then it is a necrosis, which is already a non-vascular pathology. Tsei stan is characterized by the deterioration of the functions of nirok, for the accumulation of toxic words in the body, and the stench is absolutely not vivod in the natural path.

Toxic nephropathy vimag inconspicuous treatment, In the first place, there may be some problems for the life of the accelerated life.

Toxic words, such as naughty nirkam, to finish off a lot. Some of them are consumed in the body in the process of life, in the process of life, in the case of injuries or sickness. Toxic nephropathy can occur on the basis of symptoms, or with the provision of emergency medical assistance. The main factors in the diagnosis of toxic nephropathy include:

• vzhivannya in їzhu branched mushrooms;
• otruunnya with cheeky words, important metals (mercury, honey, cadmium);
• injecting radioactivity (uranium salt);
• take in all the middle of the organic ones (scrub acid, tetrachloromethane);
• otrunnya surrogates to alcohol;
• trivial vikorystannya lykarskih zasobіv, scho take a detached organism (antibiotics, antimicrobial drugs);
• transfusion of blood inappropriate by group or Rh factor;
• important injuries or risks, if there is a large amount of tissue ruptured from the products that fall into the roof of the house;
• penetration of microbes, scho to produce before infection and septic tank.

Yak, when outnumbered by mushrooms, alcohol surrogates, or spun off, is a head problem for nirok negative influx of toxins into internal nirk structures. It is the most total destruction of robots to produce nirok that is not safe for life and health.

Toxic nephropathy can be classified for many reasons. So, see the onset of the pathology:

• Nephropathy is specific and toxic. Growing up by injecting direct ingestion into the body will wipe out and toxins. There can be alcohol, other chemicals and metals (mish'yak, mercury, lead, cadmium, synthetic rubber, oxalic acid, etc.). This is also a specific form of toxic damage that can develop and become bran mushrooms or a bite of bran / coma.

• Nonspecific nephropathy. It develops as a result of penetration into the organism of toxic speech, as it does not have a direct spill on the nirkas, but at the same time it stimulates the lack of organs. Here, the reasons for the pathology can be Rizke Padinnya arterial grip, malnutrition in the electrolyte balance, rupture of the posterior blood flow in the body and organisms in general, for non-compensating acidosis.
• The mediated nephropathy is toxic. In general, toxic speech and spontaneous disruptions in the human body are caused by the presence of such negative pathologies as blockage of the nephrons with hemoglobin, the growth of tissue tissue in the liver, and the growth of nephroliths in the liver. Sepsis (contamination of blood), the trivial process of healing the tissue as a result of injuries, and as a result of a large number of blood cells, are also the reasons for nirkovo toxic deficiency.

Among the reasons for toxic damage to both of them are the following reasons:

• Radiation optimization of people;
• Acceptance of drugs in a group of non-steroidal anti-pyretic drugs, sulfanilamides and aminoglycosides, without proper control of the drug.

Nephropathy to be repaired when infused will wipe out on a person or autoimmune reactions to his body. Perebіg ailments pummeled with a way to consume the toxin, its kind and smack. The group has people who may have permanent contact with toxins. Ale otruunnya can be done on a by-end basis. In children, the development of toxic nephropathy is amazed by the manifestation of congenital pathologies and factors that have been infused into the period of vaginosity. In the midst of dreary speeches, chronic pathologies, I see the following:

• mercury, lead and other important metals;
• otrut mushrooms;
• take away the creature and coma;
• nitrogen spoluks: ammonia, nitrobenzene;
• businessmen;
• inorganic kind;
• різні acids;
• alcoholic surrogates;

Nirki is a young organ of a small bean-shaped form. Nirok functions:

• regulation of the water balance in the body;
• participation in the control and treatment of the arterial grip;
• participation in the process of establishing blood cells;
• vivedennya products_v obminu.

Skin nirka is stored more than 1 000 000 units of filtration - nephrons. The skin nephron to avenge the glomeruli of other blood-bearing vessels (glomeruli). Being permeable, the stench allows the product to be removed from the blood and passes through the membrane. The profiled products are exchanged for the organism with the cross.

With the proper speeches, there are a lot of nagging frogs on the nephrons, as they cease to cope with their endeavors. The development of a key picture is rich in what lies in the nature of the hostile speech. Ale spіlnim є deterioration of the normal function.

Before the hostile speeches, you can add:

• soft alcohol;
• importantly;
• organic retail managers;
• pesticides;
• lykarski zasobi (in case of overdose, implantation of non-trivial or stitched preparations, failure of way of introduction).

With a lack of harchuvanny nirka, ischemia (werewolf camp) develops, and the trivial ischemia is brought to a non-reversible legacy - necrosis. Tse to produce an additional vypadannya funktsionuvannya nirok, much of which is accumulated in the body of toxic words and the unhappiness of їkh vivedennya natural way.

Nephropathy can develop under the influence of such words:

• Khimikativ - oxalic acid, citric acid, citric sulphate, nitrogenous toxins, polymers, synthetic rubber, mercuric chloride, antifreeze, dichloromethane, ethacrylate.
• Alcohol.
• Important metals - mercury, lead, mish'yak, cadmium.
• Loose mushrooms and fillet creatures.
• High doses of lykarsky drugs - sulfanilamides, aminoglycosides, non-steroidal anti-inflammatory drugs.
• Ionizuyuchoї radіatsії.

Ethiology

• the presence of metabolic disorders (diabetes, gout and inshe);
• otrunnya organizmu people with important metals;
• trivial implantation of deyakims, such as anti-fatigue, analgesics and protisnom;
• vinoshuvannya ditini;
• infusion of radioactivity on tilo people;
• the manifestation of the late-born new goodness of good and evil character;
• virobnich and pobutova intoxication;
• anomalies in the development of nirok and secular nobles and іnshe.

key picture

Show toxic nephropathy and the severity of interruption can be difficult. Often on the first place there are symptoms of gross glamerulonephritis of abnormal deficiency. A number of symptoms appear to be offensive:

• arterial hypertension (pivoting vice);
• oliguria right up to anuria;
• puffiness of an individual;
• ill-feeling in dilyantsi nirok;
• persistent appearances;
• sudomi;
• proteinuria;
• hematuria.

Also, in the form of toxic speech, there may be specific symptoms.

Threatening acceleration є nirkova lack - a symptom complex, which is a reflection of damage to the functions of nirok other reasons... It is characterized by anury and saturation of nitrogenous products in the blood. Far away, as long as there is no immediate medical help, I will develop an uremic coma on the smallest, weakness, intensive headaches, and I will get overwhelmed.

see

One of the most common types of ailments is dismetabolic nephropathy. Vona go to the list of pidvidiv:

• oxalate-calcium neuropathy. Most often, such dismetabolic nephropathy in children is developed;
• oxalate. The first signs of ailment are manifested in any kind (to visit the new generation). I do not like pathology, tobto a viscous risik to develop sechoamian ailment;
• phosphate. The main reason for the progress is chronic infection of the sechostatic system;
• urate. Buvaє yak is primary, so і secondary;
• obminna nephropathy for the participation of cystine.

Also in medicine, there are some types of nephropathy:

• diabetic nephropathy;
• vaginal nephropathy;
• toxic nephropathy;
• gouty nephropathy;
• mієlomna nephropathy;
• Iga nephropathy.

diabetic form

Diabetic nephropathy is characterized by one-hour exercise of both nerves, which can lead to deterioration of their functions. The main cause of the disease is diabetes. Diabetic nephropathy progresses generally on aphids of diabetes. Symptoms appear step by step. Clinics see 5 stages of diabetic nephropathy:

• asymptomatic. There are no symptoms. Evidence of the pathology is possible only for additional analysis;
• cob structural changes. Foul blood in nirkas is growing, as well as glomerular filtration;
• prenephrotic. The concentration of microalbumin grows up to 300 mg / dose, even if the protein is mute. Blood circulation and glomerular filtration are normal. In children, children can slightly increase the arterial grip;
• nephrotic. AT of adjustments permanently. Urine has a billock. Filtration, as well as brutal blood, is reduced. People are encouraged to increase their cholesterol levels. Z'yavlyayutsya nabrya;
• uremic. The filtering function of a significant world decreases, which becomes the reason for the accumulation of sect and creatine in the blood. Rіven bіlka go down even more, through scho to get more swelling. AT can move up to critical indicators. Practically, all clinical patients are given the stage of diabetic nephropathy step by step to nirkova lack.

vaginal nephropathy

Nephropathy of vaginal є one of the most insecure people hastened the hour before the fetus is celebrated. The reasons for the progresuvannya ts'go will not vivcheni until the end. The group has young girls and also who regularly live alcohol and smoke cigarettes.

Nephropathy of the vaginal parts is diagnosed in the other half of the vagina. The child has an arterial grip to high digits, there are some quirks and proteinuria. If it is often not possible to adequately treat the nephropathy of the vagina, then the greatness of Wikipedia is great. A woman with such a diagnosis is tested in stationary minds, and is constantly monitored in the country.

It also means that vaginal nephropathy is not a severe pathological camp. During the remaining hour, the progress of ailments significantly increased.

toxic form

Toxic nephropathy is progressing by cutting off the organism by means of destructive sponges. The first symptom is a greater number of perceptions in the projection of nirok. Further, the clinical picture of toxic nephropathy can be supplemented with the following signs:

• swelling;
• oliguria;
• anurya;
• shelter in urine;
• block in urine and nitrogen base.

It is important to carry out the treatment of toxic nephropathy more efficiently, as it can lead to the development of a nirkova deficiency.

gouty form

The basis of the progression of gouty nephropathy is the acceleration of the formation of secular acid in the hopeful vivedennya z tila. Yak inheritance, speech is accumulated step by step in the bloodstream and urati is formed in nirkas. As soon as gouty nephropathy will progress, then it will lead to deformation of tissue nirok. The visual and the filter of the building is very low.

mієlomna form

The main manifestation of malignant nephropathy is the progression of proteinuria and steps in the development of a nirk deficiency. It is obvious that, given the form, all the signs are indicative of nephropathy, on the day. But at the same time, dysproteinemia and hyperproteinemia are promoted. It is also common for patients with such a diagnosis to develop nephronecrosis.

Iga nephropathy

Particularly Iga nephropathy є macro- or microhematuria in the future with protein. As a rule, an ailment will be repaired to progress through a few days of a sick ailment of the upper, dysfunctional, daydreams.

Also, with Iga nephropathy, hyperthermia, arterial hypertension, nephritic syndrome, pain in the disease nirok, dysuric symptoms are observed. Iga nephropathy is also characterized by recurrent interruption.

More quickly diagnose:

• recession nephropathy;
• simeinu;
• Paraneoplastic;
• tubulointerstitial;
• analgesic;
• endemic;
• hypertonic;
• membranous;
• reflux;
• contrast induced;
• lykarsku.

Symptoms and stages of illness

Toxic damage of nirok can be classified behind the steps in fallowness due to the severity of the sick camp. So, the development of such stages of pathology:

• Light foot otruunnya. At the same time, the patient in the battle will have a block, erythrocytes and an increase in the strength of the battle.
• Middle stage of pathology. To the already obvious symptoms, there is a decrease in the amount of extra fat, as well as an increase in calories, creatine and other metabolites in the body of a sick person.
• When the stage is important, the detachment a sick person develops a nirkova deficiency, which can lead the patient to the Komi.

The symptomatology of the pathology is poured over by the amount of toxin, having consumed the organism, the stage of development of toxicosis and the backward camp of the sick person's system. With the presence of chronic ailments of nirok, stoves, or slaughter, to finish off a small amount of off for a cob of a pathological camp. Nephropathy is toxic for the following symptoms:

• a change in the volume of the battle, right up to the rest of the day;
• p_advischennya arterial vise;
• weakness, drowsiness, lethargy;
• tediousness, often bloating, a lot of blood houses in bloody masses;
• transverse pain;
• swelling of conviction and tila;
• rozlad to the slunk;
• sudomi;
• zadishka, you can wheeze in the legends.

In case of intoxication with singing words, to the distant ones, there is a sign of specific symptoms, for example, when a patient is poisoned with streptocide or norsulfazole, the patient has "aches" in the slopes and a hot camp. The appearance of such indications of their symptoms dopomagaє lіkarevі vis-à-vis the type of otruti, with diagnostics.

The development of nirkovo deficiency is divided into 4 stages:

• Initial. It is characterized, bezposeredno, injecting toxin on the body, can be up to 3 dB.
• Oligoanuricheskaya. At the stage of the stage, the organism of a non-lethal increase in vivodity ridin, which causes swelling, badness and wheezing, as well as the development of the growth of the brain. The triviality of the stage is up to 2 types.
• Polyuricheskaya. The stage is to talk about friendly protesters. It is characterized by an increase in diuresis, which is not infallible to the organisms. A stadia is given, a trivial little bit of miscellaneous or rocky.
• Oduzhannya. Normalization of robotics and good results and analysis of the section. Outside of renewal, not all patients are seen.

There are three stages of toxic nephropathy:

1. Easy.
2. Middle.
3. Vazhka.

Easy reversible step: at correct love You can easily update the robotics. At the middle stage, a concentration of toxic words grows in the blood, which is normally carried by nirkas. At an important stage of toxic nephropathy, a nirkov deficiency develops.

signs of ailments

• significant changes in the number of incidents of the Kremlin (oligoanuria);
• reduction of arterial grip;
• zadishka bends;
• pain of the іznogo level of intensity in the sides or across.

You can easily manifest symptoms in people who are tied with the help of a toxin in the human body:

• nudity and bloody vomiting;
• carry;
• pain in the upper abdomen;
• swelling of the intestines;

The nephropathy of the state institution of pathology with a threat to health and life is toxic. Ailments can lead to a hostile deficiency, which becomes a cause of death or a trivial treatment for hemodialysis.

Toxic nephropathy is characterized by onset symptoms:

• nudity and bloody vomiting;
• carry;
• pain in the upper abdomen;
• swelling of the intestines;
• loss of sleepiness and drowsiness to an uncomfortable stun.

The nephropathy of the state institution of pathology with a threat to health and life is toxic. Ailments can lead to a hostile deficiency, which becomes a cause of death or a trivial treatment for hemodialysis.

The outward symptoms of toxic waste of nirok with small spits last for several phases, and with all the signs of pathology, they will be deposited from the phase itself.

• So, for іnіtsіalії phase Nirkovoi lack of a sick person will be spared a decrease in the amount of money in the battle. The phase is trivial from 1 to 3 days in fallowness from the detachment step.
• With oligoanuric phase the patient can develop a birth in the body, which is brought up to the overwhelming re-entanglement of the heart. Likewise, a sick person may develop a syndrome of a vologic lung, which will be characterized by wheezing and dullness. At the stage of the phase, the patient has a lot of development to the brain and legends. In the body, there is an intensive accumulation of slags (products of alcohol exchange). There may be traces of the glamor and weakness. The heart can be zupinka. Qia phase trivaє 7-14 days.
• The phase is polyuric. As soon as lykuvannya will be recognized correctly, and the patient's organism will give a one-time definition of pathology, then the frontal phase will turn into polyuric. In the whole vipadku zagalny obsyag sich will be zbіlshuvatisya with a skin day. At the extreme end, a dobovy obsyag can be up to 35 years for dobu. During the whole slaughter, mother will be low on the pitched vagu. Here they are respectable, because the phase can lead a sick person to anger. Phase trivaє 15-30 days.
• Then it’s the period of time, when a pitoma of the wag is cut and її a good deal will be normalized. The lingering phase can take 6-24 months.

In general, in the home minds, toxic detachment at the early stages may include the following morphological signs:

• Pull the pain across;
• Lumpiness of nіg і individuals;
• Post_yna spraga;
• Deyaka zhovtushn_st shkiri and її dryness;
• Visipu can be shown on the lobes from the inner side;
• Nudota, carrying, blues;
• M'yazova and head bill;
• Rizke change AT from a sick person;
• Decreased obsyagu slaughter;
• Glamor, flattery, hallucinations.

Symptoms and stages of illness

The development of a clinical picture of pathology lies in the concentration of drinking a toxin in the body, because of the individual peculiarities of a particular person and because of the fact that the function of the patient has been impaired. Toxic nephropathy appears mainly by offensive signs:

• Winery is in the area of ​​projection nirok, it is most often dull and dull;
• The guardian self-esteem, there are intoxicating signs;
• The deterioration of the function of nirok wede to the development of swelling, in the section there is a block and shelter, and the number of changes changes.

Pathology has grown into three stages of severity in fallowness, because of that, the nirkov's function has been impaired.

1. With an easy step, the symptomatology is not sharp, in the section there are changes in the blocks, hematuria and leukocyturia.
2. At the middle stage, to all pererakhovanih sign of oliguria, in the blood appears the growth of the sevina and creatine.
3. With a difficult step, the patient will reestablish all the signs of a hostile nirkovoi lack.

Symptoms of toxic nephropathy and the severity of ailments can be significant. To achieve often more swelling symptoms of ailments appear - nircum deficiency and glomerulonephritis. Signs of nephropathy can be seen in the following health deterioration:

• stable grip;
• oliguria or zh anuria;
• swelling of denunciations;
• ailments in the area across;
• sechovipuskannya, more low for 4 years;
• strong judgment;
• proteinuria;
• hematuria.

The severity of the ailment can be associated with recurrent symptoms. Symptomatology is susceptible to toxic damage from the first days of a nirok і stepwise build-up.

The most unsuccessful accelerated nephropathy is affected by a nirk deficiency. In a wide range of functions, there will be more damage and it is practically impossible to work organically. With such a pathology, all abrasive speech is absorbed in the blood; If you do not pick a sick person at once, then you may develop an uremic coma, which is characterized by apathy, weakness, mildness and characteristic nodding.

In case of toxic lesions of nirok, a lot of people appear on the face, so it is important to miss such a pathology.

At the early stages of progression of ailments, symptoms may not be spared at all. But in the world of yogo development, the following alarming signs appear:

• feeling sprague;
• weakness;
• p_dvischena stomatomy;
• head b_l;
• most of the views in the projection of nirok.

on in different stages The key picture is supplemented with such signs:

• visible swelling of the fabric;
• Sudin is not the grip of growthє;
• in urine there are bilkovy structures;
• You can easily manifest symptoms of polyonephritis, in times of penetration of infectious agents into the organ.

Zahvoryuvannya maє show this:

• bіl u dіlyantsі nirok;
• embellishments of denunciations and lower pictures;
• sprague;
• dryness of shkіri і mucous, with hemolysis - zhivtushnіst;
• scarlet fever, or the bark is similar to the visipa;
• beating in the stomach, nudity, bloating, bright style;
• anemia, increased bleeding (petechia, ekhimozi);
• temperature adjustment (in fallowness in the form of detachment);
• schism to infection;
• bіl in meat, head bіl;
• falling arterial grip;
• arrhythmia, blockade of the manifestation of hypercalculation;
• reduction of vision of the battle at the stage of oliguria and improvement of dyuresis in the polyuric stage;
• sudomi;
• gallantry, psychosis, hallucinations, gallant weakness.

diagnostics

• conducting ultrasound nirok.

If it will be necessary to confirm the diagnosis, to carry out X-ray and tomography (MRI or CT). Often enough bachiti klinichny show the nobility the reason for the rejection.

At the first stage of the treatment of the drug, I have great respect for the symptoms, which may lead to toxic nephropathy. Optimally, the product is distilled accurately, or even the male officials have led to nephrotoxic acceleration. Obligatory diagnostic methods for toxic nephropathy will be:

• zalnoklіnіchnі analizi sichі and bloodі;
• special dosage for the identification of the causal factor in case of exclusion;
• assessment of the functional standard of the laboratory for biochemical analysis of blood;
• conducting ultrasound nirok.

If it will be necessary to confirm the diagnosis, to carry out X-ray and tomography (MRI or CT). Often enough bachiti klinichny show the nobility the reason for the rejection.

If the cause of toxic nephropathy is ailment or ailment, then it is necessary to securely detect toxins from the blood and blood circulation. Also, there is a lack of something ailment in the hospital, and in the minds of a reanimation revision, it is necessary to carry out an emergency treatment. In case of chronic nirkovy lack of therapy, there is plenty of room for a change in the rate of change in nirkas.

Call the diagnostics to be carried out at the same time at the official nephrology, where to bring the sick person at the age of adolescence at the hospital. Besides the characteristic clinical picture, I will respect the animal's history of pathology, and the spirited character of the disarray.

The methods of treatment for toxic nephropathy are as follows:

• Zagalny analysis of blood, slaughter;
• Blood analysis for pH level, electrolytes;
• Biochemistry analysis of blood in the part of indicators of robots;
• Ultrasound nirok;
• If necessary - MRI nirok.

In case of nephropathy, the most frequent growth is SHOE, a number of leukocytes in the blood, anemia is caused. In the case of the growth, there are a number of blood cells, nitrogenous spoluks, there are hemoglobin and erythrocytes, cylinders. Pitoma of the blood is increased, and in the peripheral blood there is growth of creatine, sechovina, sechovic acid, and calories.

Frequently, toxic nephropathy is carried out in the form of emergency reanimation, especially in case of hospitality of nircovian deficiency. When there is less seriousness, the camp can go to the standard ward for the examination of nephrology (urology). It is necessary to repair a complex of visits for the therapy of ill health, but it is necessary to do it under the control of a toxicologist.

Naivazhlivіshim є come in on vivedennyu toxins, they will wipe out from the body. Tse reachable by way of following such priyomiv:

• plasmapheresis;
• hemodialis;
• hemofiltration;
• hemosorption;
• Promivannya shlunkovo-intestinal tract.

Forsivaniy dіures zdіysnyuyut the introduction of eufіlіnu, mannitol, lasix. For promivannya slunk in the new to inject vaseline oil, or a large amount of ridini. Hemodialis of recommendations in the first 6 years of illness, for more than 48 years of treatment of the peritoneal dialis (purification of blood through the stalk).

Sorbents, glucocorticoids, as well as puddles are recommended for drugs in case of toxic nephropathy. Supplement the intake of glucose with vitamin C, insulin, sodium hydrogen carbonate, calcium chloride, vitamin C. If necessary, carry out transfusion of albumin and plasma.

Schob as accurately as possible diagnoses toxic detachment of nirok, fakhivtsi conduct a number of visits:

• Zagalny analysis of blood and slaughter. At the same time, characteristic evidence of the most toxic pathology will be the manifestation of a low level of hemoglobin, an increase in leukocyte and thrombocyte, as well as a change in the rate of section.
• Biochemical analysis of blood and blood. Here there will be changes in the amount of creatine, sečovina, damage to the acid-pool balance.
• The doctor will also designate the performance of the additional volume of the section and the ultrasound diagnostics.
• Whenever a robot is seen on the angiogram.
• You can use MRI or CT scan.

As soon as the organism of the patient is cut off, it is inadvertently turned up to the toxicologist. Infectious-toxic nirka can even show a classic picture, and diagnostics does not take an hour and does not require a large amount of dosage and analysis. First of all, the doctor needs to see the type of toxin that is poured into the organ, it can be damaged after the patient has performed a number of analyzes. Among them:

• foreign analyzes of blood and blood;
• biochemical analysis of blood;
• analysis for toxin detection;
• Ultrasound nirok;
• MRI (if necessary);

As a rule, analysis of displays for an accurate value of the diagnosis. In case of toxic nirtsi in the section, there is a SHOE, a block and a bit of a section. You can increase the level of leukocytes in the blood, and talk about infectious-toxic nirtsi. Doslіgennya add to the exact stage of the disease and the stage of seriousness of intoxication. All the data are necessary for the recognition of correct treatment and forecasting of a slight overcoming of ailments.

Diagnostic procedures are carried out in the hospital. Start off the speech. Get anamnesis. The main methods of accessing є:

• clinical blood analysis;
• biochemistry of blood;
• field of water balance and water balance;
• zagalny analysis of the slaughter;
• Ultrasound nirok;
• Inodi MRI.

The standard diagnostic plan includes:

• Ultrasound nirok;
• carrying out specific tests for calcification in the section;
• biochemical dosage of urini;
• analysis of the section. Yes, there is a lot of salt crystals.

For the detection of toxic nephropathy and monitoring, I will use the following analyzes:

• Zagalnoklіnnіchnі doslіdzhennya - zagalnіy analysis of blood and slaughter (characteristic anemia, leukocytosis, thrombocytopenia, changes in slaughter).
• Biochemistry analyzes - creatine, sechovina, acid-balance, blood level (K, Na, Mg), proteinogram, hypothesis assessment.
• The value of the dobovogo diuresu.
• Ultrasound nirok.
• Roentgenogram (oglyadova, from contrasts).
• Angiography.
• Excretory polygraphy.
• CT, MRI.

lykuvannya

Whether from nephrotoxic factors can cause to clutter up the life stan_v. As soon as there is a test of nirok, then it is important to immediately start looking for more medical help. The main methods of eliminating toxic nephropathy are hemosorption and hemodialis, which allow quick and effective cleaning of the blood from a toxin. If everything is broken correctly and every hour, then the chances of getting better and the prognosis are friendly.

To achieve often toxin toxic nephropathy in the minds of resuscitation, especially if the ailment is slowed down by a nirk deficiency. If the ailment is not very important, then it is allowed to treat the ailment in the established urology.

In the most recent period, the most important workers є the rate of production of toxic words and products in metabolism and organism. For a good idea, you can use the following methods:

• plasmapheresis;
• washing of the intestinal tract і;
• hemosorption;
• hemodialis;
• hemofiltration.

Forcing dures is carried out by the introduction of new medicines. Schob clearly cleanse from toxins in the intestinal tract, inject vaseline oil into the new one, or a great obsyag of ridini. It can be clean water, a weak level of manganese or a water pidsolena. Hemodialis is an effective deprivation in the first 6 years from a cob of ailment, when it is necessary to carry out the cleaning of the blood through the stalk.

The sick person is shown drugs from other drug groups. The patient is guilty of accepting sorbents, hormonal drugs and antihistamines, you will be able to identify the development of important allergic reactions. In addition, glucose is shown with vitamin C, insulin, sodium hydrocarbonate, calcium chloride and a complex of basic vitamins.

Varto respect, how toxic nephropathy is disgustingly addicted, to that, how klitini nirok is disgustingly fed up to renewal. Nephroni can look at the very early stages of getting sick. As a result of the function, it will deteriorate. It is very important to fix the disease itself through the process when the first symptoms of ailment appear.

Toxic nephropathy ailment is guilty of living in abundant pitta. Tse spriyaє shvidku oduzhannyu.

The main factor in the treatment of toxic nephropathy is the development of nephrotoxic organisms. Basic options for therapy є advanced methods:

• As soon as the mushroom bullet is taken, or the simultaneous intake of a great number of medicinal preparations, then it is necessary to reduce the slurry.
• In case of a spraying from industrial or chemical sprays, it is recognized as an antidote (a drug that can be used in organisms).
• To see nephrotoxin from the blood, it is necessary to use the hemosorption method (with the help of an active patient).
• in especially folding vipadki it is necessary to carry out hemodialysis.

Any of the nephrotoxic factors can lead to dangerous and clutter up the life of the countries. As soon as you have a chance to study nirok, then it is important to get a good medical help. The main methods of eliminating toxic nephropathy are hemosorption and hemodialis, which allow quick and effective cleaning of the blood from a toxin. If everything is done correctly and every hour, then the chances of getting better and the forecast are friendly.

In case of severe rejection and intoxication of nirka, you can become astonished with a development of toxic nephropathy. Only a little more quickly can help people to uncover an important acceleration of such manifestations - a nirk disadvantage.

As a rule, all therapy is focused on detoxification of the sick person's body and on the renewal of robots. Criteria for which medication therapy is assigned, to lie down because of the severity of a sick person. Altogether, in the first place, the following complex of preparations is recognized:

• Specific antidotes.
• Diuretics. Bezbechuyut decrease in swelling and increase in volume.
• Polyinfusions. To the ailing person to introduce razchini to normalize the pH of the section.
• The transfusion of blood components is also indicated.
• For the purification of blood from toxins, plasmapheresis or hemosorption / hemodialysis is an apparatus for pumping and purifying blood.

Likuvannya is carried out in a hospital in the context of renal nephrology and not in the early stages of revival. Fakhіvtsі toxicologists get involved.

An important stage є vivedennya toxin from the body - the weakening of the cause of the pathological camp.

Come on in:

• hemodialis;
• plasmapheresis;
• prominence of incoming toxins, for example, early sequestration of the slunk;
• hemofiltration;
• forcing dures(From the stasis of osmotic diuretics);
• Protishokovi come in.

3 preparations in complex therapy zastosovytsya sechogіnnі, glucocorticoids, sorbents and іsne puddles. For an hour of drinking, a post-bed regime is assigned. Z ratsіonu viklyuchayutsya products, bagatі on bіlok, for example, meat, eggs. In case of manifestations of the uremic uremia, it is guilty of but also in carbohydrates.

When saving the visual function of nirok, it is recommended to use ryasne pittya (3-4 l / day), Bazhano licorice. Especially respect comes to the cleanliness of the shkiri, so as to see through non-toxic products provoke sverbіzh and comb. In case of sharp swelling and frequent vomiting, it is necessary to drink, as sodium chloride is consumed in the process of vomiting.

At an important stage, the prognosis is unpleasant, since the renewal of functions is not seen and the patient is not seen. The lethality is due to the following factors:

• type of otruynoi speech;
• yogo number;
• outgoing body and health nirok;
• hardness of interruption;
• vysokochasno rozpochaty lіkuvannya.

Toxic nephropathy is a great malignant state, a little bit more dangerous before the disease and early detection of pathology to increase the chances of a successful outcome.

The plan is to break up only for the reason that a type of pathology will be accurately established, which will infect people.

Diabetic nephropathy at the first and other stages is not specific to the disease, it is necessary to reduce the concentration of sugar in the blood between normal values. So, the pathology progresses on aphids of a sugar-coated diabetes, it is important to take care of special children. It is also often used before the introduction іngіbіtorіv APF, And also hemodialysis. Even if all come in not effective, you can go in before organ transplantation.

The treatment of vaginal nephropathy is carried out only in stationary minds. Therapy is offensive:

• strict post-bed regime;
• preparations with a vmistom of a bottle;
• diuretics;
• antiagreganti;
• preparations of kaliyu;
• hypotensive problems;
• antispasmodics.

Treatment of toxic forms is carried out with the help of forced duresis, slurry washing, hemosorption, plasmapheresis, hemodialysis and іnshe. In order to normalize hemostasis, you can stop trying to do it.

The basic principle of dismetabolic nephropathy treatment:

• normalization of one's way of life;
• dієtichne kharchuvannya;
• drug therapy. Vitamin E, Vitamin A, Vitamin B6, Dimephosphon and Inche are used to treat ailments.

Likuvannya in case of gouty form in Persha Chergu is straightforward to the weakening of the main ailment - gout, for which further therapy is carried out:

• implantation of the great number of birth;
• the plan of lykuvannya obov'yazkovo complement sechoginnymi;
• hypotensive drugs;
• antibiotics (as opposed to infectious agents).

Therapeutic go straight into the Perch of Chergu on the weakening of the causal factor. In case of infusion of toxins, detoxify with additional intensive infusion therapy and apparatus cleaning of blood.

For the treatment of toxic nephropathy, the following preparations are used:

• Specific antidotes.
• Diuretics. I mean, with a decrease in deiureza, for a lot of problems, including a lot of legends. Most often it is used for Mannitol, Lasix.
• Polyionny roschini. For normalization of blood pH, inject sodium hydrocarbonate.
• Components of blood. To carry out transfusion of plasmi, albumin.

For the introduction of toxic speech vikoristovuyu use the following methods: hemodialysis, peritoneal dialysis, ultrafiltration.

therapy

Lіkuvannya is direct on vivedennya toxins. As the nephropathy of the wiklikan is hospitable to the otruєunnyam, then in the first year the scrubbing of the slunk is shown. In hospitals, there is a method of forced duresis, anti-toxicity and anti-toxicity therapy.

Persha dopoga

• In case of adolescence on toxic otrunnya slid yakomoga shvidshe nadati sick dolikarsku will help. In general, it is necessary to pinpoint the necessary toxins in the patient's body. So, if you do not want to go by the way, then you need to prevent the sick person from doing it (move him to the street, far from the infected person), as if they had taken it to the body through the mouth, then it would be necessary to carry it out. A simple water treatment is immediately recommended. In the quality of the sorbent, it is possible to give a sick person an asset.
• Since a sick person has a loss of testimony and heart, it is necessary to carry out a piece of work and indirect massage of the heart. Until all visits are made, I will help you.

Folding and forecast

Be it nephrotoxic infusion can be the reason for the defeat of nirok, from which traces of vision:

• Gostra nirkova lack of - how to appear in high reductions, or more to see more.
• Chronic nirkova lack - winikla yak the result of a hospitable camp, or in the case of a merry-go-round.

Toxic nephropathy - tse mayzhe zavzhdi vipadkov, or hate being exposed to the organism of abnormal abnormal speech. Nirkovi accelerated important ailmentsі lykarska nephropathy develops significantly earlier.

The prognosis of becoming ill without the middle of the out-of-mouth speech, it has penetrated into the body, as well as the severity of the toxic nephropathy. The number of fatal diseases in the case of many ailments can be reached over and over and up to 70% of all those who are ill. But it does not mean that if people get rid of their skin, it will threaten death, with a timely diagnosis and adequate treatment, the prognosis is good.

The highest prognosis for nephropathy in the same way, as the body was consumed by such chemical words, such as cadmium, silicon and arsenate water.

Uskladnennya most often z'yavayutsya when significant hit in the organism of the bran speeches, and through the roof. The most unsuccessful acceleration is a nirkova disadvantage, it is often fatal to fatten the yak.

Toxic nephropathy - tse duzhe not uncomfortably ill nirok, yake, with unseasonable lіkuvannі, produce up to a number of accelerated. Varto pam'yatati, scho klitini nirok is nasty to be renewed and from earlier razpochaty lіkuvannya, tim friendly forecast.

Nephropathy is toxic because of the damage caused by toxins and products of biological growth to deterioration of normal functions. Shkіdlivі speeches are consumed in the body izznі or can win through the ailment.

The prognosis for toxic nephropathy lies in the type of branch speech and severity of ailments, the lethality is 20-70% in the fringes. Friendly prognosis only with the adequacy of therapy and freedom. The highest prognosis when cadmium, silicon, arsenate gets into the body.

The folding most often develops with a high concentration of toxins and is wiped off into the body, when it is victorious, not through the shorts, but through the roof. Hemolytic-uremic syndrome, interstitial nephritis, state of the art nirkova deficiency are recognized before acceleration. It is not said to be accelerated to often lead to death through necrosis of some and all other functions.

The incidence of correct treatment in case of rejection may lead to severe inheritance, such as hemolytic-uremic syndrome, nircum deficiency and interstitial nephritis. The most insecure camp is a nirkova disadvantage. Pathology is characterized by partial abnormal exit to the organ. It is fraught with coma і, like inheritance, necrosis - in nirka's injuries. Nirkov's lack often ends with a lethal result for the patient.

prophylaxis

• As a rule, a specific toxic nephropathy occurs in folding chemical enterprises and in the Silk state government. In general, you can guard against any risk of pathology by moving the fence on the robot to persons who may be able to solve problems, risik until the pukhlin is approved.
• In addition, it is possible to reduce the amount of toxic damage by the method of mechanization of the enterprise. In such a rank, direct contact between people and chemists will be made to the minimum.
• We work at chemistry enterprises to wear old clothes.
• shown very well medical care people who work with chemists. I especially respect nirkah.

Varto of the nobility, who earlier became ill, will be more effective than this. Modern medicine is completely successful in coping with toxic nephropathy.

The friendliness of the result is amused by the kind of toxin, the triviality of it in the flow and the free diagnostics. Statistically, the incidence of vilikov is 20-70%. Prophylactic come in additionally to help reduce the risk of toxic nephropathy. Often the pathology of the diagnosis is due to overdosing with drug addiction, taking drugs only for the signs of the drug and, according to the instructions, to prevent toxicity.

A slid of maturation is seen in living in the most common species of mushrooms, in alcohol and in alcohol of low quality. Talk about prophylaxis in the professional sphere of activity, victorious individual tasks for the individual, special form, adopting the technology of safety and regularly bringing up the doctor to create a minimum of chances for developing

Chronic deterioration of nirok sposterіgayut on virobnіstvі polymers, rubber, in silskogospodarsky robots. People who are with a high rizik development of fluff and background ailments nirok. An important role in the preventive maintenance of mechanized practice with the maximum interconnection of contacts in people and chemists is important.

In case of professional contact with toxins, it is necessary to thoroughly pass the test. It is necessary to take into account the hygienic norms for virobnistvі, wear the worn clothes. When the cob changes are detected, it is recommended to change the robot.

At the end of the next story, you have succeeded in the process of lying down without an hour before medical pledge... At the first signs of nezduzhannya, it is necessary to go through a routine. From the stakes modern methods lіkuvannya toxic nephropathy is possible vilіkuvati. Good luck!

Scho also Toxic nephropathy

Vidіlyayut specific urazhennya nirok at gostrich exotoxicosis. They are tied with nephrotoxic words: ethylenglncol, oxalic acid, mercury, chromium, lead, mish'yak. Nephropathy of vinicum is toxic when it is cut off by hemolytic flutes (ostic acid, mish'yakovy water, medium vitriol). The deterioration of the function of nirok develops along the way toxic lesions liver (hepatorenal syndrome).

See nonspecific nirok. It manifests itself in the case of an important detachment with small snacks, as well as in the case of hemodynamics (primary toxigenic collapse, ETS). It’s a great time in the structure of the fight against the syndrome of positional compression, which is the acceleration of coma.

Pathogenesis (how to see?)

Pathogenesis of toxic nephropathy There is a lot of things to be found in ethology. When stripped with ethylene glycol and oxalic acid, the dressings are filled with a bundle of nephrons. The specific nature of mercury salts is summarized by the linkages of sulfhydryl groups, which can lead to the destruction of the cell dynamics of nephrons and the principles of cells. A similar mechanism for the development of other salts of important metals.

When the hemolytic sprays are cut off, the erythrocytes are ruined and vilny hemoglobin appears, which clogs up the nephron. With the syndrome of positional depression of the nephron, it is increased by the amount of myoglobin. Hepatorenal syndrome of accumulation of toxic lesions with high amino acids (leucine, tyrosine, etc.).

All the meanings are the reasons to produce to the ischemia of the membranes the clitin of the nephrons. Ikshcho ischemia is trive, kilka dib, there are necrobotic worms in the glomeruli and tubules.

Symptoms of Toxic Nephropathy

Klinichna picture. There are three stages of toxic nephropathy:

• Easy foot characterized by the appearance in the section of the white, forms of elements in the blood and cylinders.
• middle step to manifest itself, in addition to significant symptoms, decrease in dyuresis, in other conditions of sevine, creatine, calories and other metabolites.
• important feet characterized by a picture of a hostile nirkova lack (GNN).

Gostra nirkova lack

Vidіlyayut іnіtsіalny, olіgoanurіicheskoy, polyurіcnі phases of arrester arrester and period of use.

The initial phase of ARF is trivial 1–3 dB and is characterized by signs of gallant rejection by speech from nephrotoxicity. In cich ailments, it is necessary to monitor duresis, when it is lowered, stimulation is carried out with 16% of the main dosage, lasix (100-200 mg per injection) in the presence of euphilin.

Oligoanuric phase is trivial 7-14 days. The most important is the opposite phase of the arrester. At nіy sposterіgaєtsya decrease in diuresis (less than 500 ml / add olіgurіya, less than 50 ml / day anurіya), catching rіdini (gostre vodne otrunnya gіdremіya) wiklikє reversing lіdіdіnіchka, appear in supologous lungs. You can develop a lot of legends and brain. In the body, slags and perch accumulate for all products of the alcohol exchange: creatine, sechovine and middle molecules, and after a few days it will move 3-4 times. There is weakness, galvanizedness. It is also possible to induce intoxication with calories, with hypercalculation of 811 mmol / l, the rhythm is accelerated and the heart is revived. At the EKG, a decrease in the amplitude of the QRS complexes, a possible development of the synoauricular, atrioventricular and internal sinus blockades, is indicated, which means a hypercalculus tooth of Tudy vysokimus.

At the stage of shvidko acidosis, the pH drops to 7.3. Metabolic destruction induces blood formation (hemosynthetase), anemia growth, thrombocytopenia, secondary toxic vasculitis. All the same can lead to bleeding and development of DIC syndrome. razdratuvannya cystic brain toxic words supervise leukocytosis due to leukocyte formula.

Polyuric phase. With a friendly interruption of the arrester of the oligoanuric phase, go into the polyuric phase. Pidvishchuєtsya, and then the build-up deuresis at low breeding vases. Inodі vіn reach more 35 l / day. The price is tied to the damage of the reabsorption of water and salts by the tubules of the ephrois. So polyuria can lead to anger and hyposalemia. The triviality of the phase of polyuria becomes 1530 days.

The period of life is characterized by step-by-step adjustments to the growth of the vagina and normalization of homeostasis. The whole process goes from 6 months to 2 years.

Mortality in acute renal failure occurs in wide gaps (from 20 to 70%) in fallowness due to an ethological factor.

Lіkuvannya differentiate on the provision of additional help to a sick person in toxicological and somatogenic phases of rejection. At the toxicological phase of the drug, go directly to detoxification and reduction of toxic nephropathy. In somatogenic phase, there is a syndrome of hostile deficiency. In case of decreased dyuresis, conduct iogo stimulation with manitol (500 ml of 16% range internally, jet 2 times for dobu) or lasix (100 mg internally, jet, 2 times for dobu). Direz will do it with the internal introduction of the euphilin.

In the phase of oligoanuria, internally, drop by drop, give a dose of 500 ml of 20% glucose in a dose of 5 ml of 5% in ascorbic acid and 16 OD insulin for the reduction of the intoxication of wheat and calories. With the method of liquidating acidosis, inject 250-500 ml of 4% sodium bicarbonate (with control of the pH of the acid). For updating the level of calcium and increasing the hemorrhage of indications of 1% of calcium chloride (150 ml). It is recommended to transfuse plasma and albumin, Vitamin complexes, Preparations, scho polishuyut exchange of rechovin (actovegin, solcoseryl, cytochrome, cytomac). Anabolic hormones (aerobol, retabol) are indicated not earlier than after a period of time.

Adjustment of the ryvnya to 30-40 mmol / l and calories at 67 mmol / l are indicated for hemodialysis. With massive fillings, carry out ultrafiltration. The appearance of hemorrhagic syndrome and collapse is contraindicated before these methods of treatment. You can vikoristovuvati for detoxification method of peritheal dializu.

It will stay for an hour with a good time to stop lymphorrhea in a bottle of 1000-4000 ml. In the phase of polyuria, it is necessary to follow the electrolyte balance to the body.

Likuvannya Toxic Nephropathy

The first type of entry is ethiological, as it is of a prophylactic nature and is most effective in case of a time-consuming stagnation in the first year of illness.

To navigate with an important dichloroethane poisoning, at times even early in the early visits on the accelerated removal from the body, the clinical picture of toxic hepatopathy appears to be more friendly, without the appearance of liver deficiency.

In the case of hepatotoxic fluids, it is justified to immediately conserve the drug in the bloodstream from the visualization of the fluids to the body: early production of the slurry with further injections of the vaseline oil into a new concentration of blood (blood) control, but not in the adsorbent peritoneal dialysis stretching 1-2 dB with an increase in the ability to stimulate cicholysis from the fat depot of the omentum.

Theoretically, it is entirely possible to substitute a specific standard, specially prepared sterile oil, which is specially prepared sterile oil, for example, Interlip, which is a meaningful change in fatty drugs. Rationally, one hour a forced duresis was carried out more quickly than osmotic diuretics (sorbitol, manitol). Hoch Quantity vidіlenih hepatotoxicity rechovin of secheyu small, zastosuvannya osmolality dіurezu dozvolyaє pіdvischiti osmotichnіst epіtelіyu kanaltsіv nirok to become funktsіonalnoї gіdropії, yak znizhuє resorptive funktsіyu epіtelіyu i in yakіys mіrі oberіgaє Yogo od Roughly poshkodzhen nephrotoxicity abo amіnokislotami, SSMSC vidіlyayutsya poshkodzhenoї pechіnkoyu, SSMSC in normі dezamіnuєtsya ...

Until then, you have a toxic nephropathy.

Toksiklog

05.04.2019

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