Rozchin enalaprilat yak for extra help for hypertension. Enalapril: іnstructions іf stasosuvannya, analogues and advice, prices in pharmacies in Russia

In extreme cases, it is possible to achieve a term and effective purchase unfavorable symptoms, It’s hard to get around this form of drugs, like a tablet. For example, in case of a hypertensive crisis, only the internal injections of such an antihypertensive drug, such as Enalaprilat, can be reached.

Diznaєmosya lectures about its components and particularities of storing.

Deduction of chemical names (S) - 1- (N - (1-carboxy-3-phenylpropyl) - L - alanil) - L - Proni, Enalaprilat is an active metabolite (product of speech exchange) of the "prodrug" Enalapril. In a pure viglyad, the speech is viglyad with a bilyastiy powder, like a volodya hygroscopic power (picking up a vologue from the most recent middle ground). For the preparation of the powder with enalaprilat, the powder is reduced with the rinines in different proportions:

• with water - 1: 200;
• methanol - 1:68;
• with dimethylformamide - 1:40;

In іnshikh іrky z'єdnannyah powder Enalaprilat rozchinniy velmi is weak.

Chloroform Enalaprilat may not differ. In dermal ampoules, the drug contains 1.25 mg of enalaprilat for dermal mildew.

Shown to sucking

Possibility to fix it with enalaprilatom for the treatment of hypertensive ailments, especially in the phase of hypertension - with a hypertensive crisis. The process of accelerating arterial hypertension is not without fail internal organs So called organisms-targets, which can be the heart, nerves, brain or the central nervous system.

That ін'єкційне introduced, yakim є Enalaprilat (rozchin), is the most optimal way of an effective, albeit smooth reduction of the vice with:

• hypertensive ailments, as well as oral intake of ill-feeling;
• hypertensive crisis, if a trivial is required, alean antihypertensive effect;
• in case of hypertensive encephalopathy - accelerated hypertension, which rotates to the lesions of the brain.

Enalaprilat guide

Information, how to get revenge in the abstract before the first drug, to get revenge on some of the main books lykarsky drug Enalaprilat rozchin. Instructions on how to get rid of the following recommendations:

• dozuvannya;
• method of introduction;
• contraindication;
• overdose;
• confusion with other labels;
• side effects;
• special recommendations for victorian.

Dose-up and supply-up methods

Otzhe, in case of an inconspicuous situation, a strong viklicana (about 200/110 mm Hg.)

1. Introduced guilty, we will be in charge, strumenevim (with a stretch of 5 chilines) or even drip.
2. The confessions are carried out in the minds of the stationary under the respectful control of the sick person.
3. If the result is insufficient, after 1 year, the injection can be repeated in the same dose, and after 6 years, switch to the mode of 1 ampoule of skin for 6 years.
4. Hypertensive patients who are taking diuretic drugs are allowed to administer the cob dose in a dose of no more than 625 mcg of enalaprilat. re-introduction if the results are not satisfactory - after 1 year in the same amount, and after 6 years you can switch to a second dose - 1.25 mg of skin for 6 years.

Overdose

The introduction of high doses of enalaprilat provok Rizke Padinnya a vice (transient hypotension), which can often be a collapse, or a hypoxia of the brain.

To that, in case of hypotonic manifestations (AT lower than 100 mm Hg) Slid:

• the speed of the dose or the change in the form of the drug;
• in important vipadkakh - laying the sick person on a flat surface without a pillow, to prevent a surge of blood to the brain;
• to conduct a visit for an increase in the circulating blood volume (volume of circulating blood) - to introduce fizrozchin or blood substituting substances;
• In the case of symptomatic therapy, it is recommended to introduce Epinephrine (internally or pidshkirno), which is from antihistamines, internally hydrocortisone, angiotensin II, or go to the procedure before the dialysis.

Consistency with the smallest tags

Do you pour in the solution with enalaprilatom parallel to the implantation of the other faces? In the instruction, from the storing of meanings, there are changes in the settings, which are developed in a special connection with enalaprilat.

1. Immunity of development of hypotonia in patients with one-hour implantation of diuretics, other hypotensive disorders, opioid analgesics and general anesthetics.
2. The hypotensive effect of enalaprilatom reduction is reduced with the parallel implantation of ethanol, medications that stimulate the renin-angiotensin-aldosterone system, adrenostimulants, estrogenic drugs (non-steroidal anti-inflammatory drugs).
3. Risks of the diagnosis of such important blood pathologies, such as neutropenia and agranulocytosis, appear on aphids of alopurinol, immunodepressants, cytostatics, which are parallel to the treatment with enalaprilat.
4. It was revealed that the hypoglycemic effect of the insulin and the old sulfonyls was improved on the background of the disease (synonymous with enalaprilat).
5. The backwash of the lithium, which is the wininic, with the parallel implantation of this preparation with enalaprilat, is creep in the case of the first, and the other.
6. In case of parallel implantation of high blood pressure dyuretics, cyclosporins, preparation of high blood cells of hypercalcium.

The number of negative manifestations in parallel implantation of beta-blockers, prazosin or hydralazine, blockers of other calcium channels, nitrates, methyldopi, and on the basis of digitalis was not mentioned.

Ethiological classification of arterial hypertension

Kerіvnіstvo on zasosuvannyu in case of serious pathologies

The patient is guilty of being responsible for his treatment with enalaprilat, as he prepares for a surgical operation. If pathologies are evident, the fault is guilty because of the guardianship, or in the back.

1. Therapy with enalaprilat does not frequently provoke the development of an aneurotic nodule.
2. As a result of vikoristannya enalaprilatom, it is seen when the patient has stenosis of the nirkovy arteries.
3. Sertseva's lack of swelling and hypotonia can provoke arterial hypotonia in patients with enalaprilatom.

Transient, as a result of the therapy with an ACE inhibitor, as a rule, mine. Moreover, with the correct regulation of the BCC and AT away vikorystannya tsikh lіkіv badly tolerated by patients. As a result of the diagnosis, hypotension is symptomatic, the dosage of the medication can be changed, or it is considered as a result of the treatment.

Prototype indications and side effects

Non-transferable counter-indications for victorian razchin enalaprilatom є navni factori:

• vagina and year of breastfeeding (as a woman needs a love, a year of pregnancy);
• up to 18 rockets;
• development of porphyry (decline pathology of the pigment exchange);
• nadmirna diminished to enalaprilatu, including drops of angioedema.

Chi is not protested, but it is recommended to be protected in singing drops:

• with aortic abo-mitral stenosis;
• with thrombocytopenia and other types of muscle suppression;
• nirkova lack;
• obstructive-hypertrophic cardiomyopathy;
• in diabetics;
• in ailments with CHF;
• s giponatrієmієyu;
• cerebrovascular pathologies;
• for the operation, associated with the transplantation of nirka, and other pathologies.

It is not possible to vikoristovuvati Enalaprilat to people who have been abducted (from 65 years of age), and also if they stay on hemodializi, because they vikonuє dyetichny ratsion, which is surrounded by the implantation of salt.

show

Inodi therapy with enalaprilat should be carried out to the development of secondary activities:

• breakdown in the system of heart and sudin - hypotension, manifestation of deficiencies, emboli (blockage of the sudin), angina pectoris and infarction;
• damage to the nervous systems - peripheral neuropathy, anxiety, pain in the head;
• respiratory depression - bronchospasm, pneumonia, cough;
• in the organs of etching - to the point of boredom, the distribution of the functions of the pancreatic cavity, the liver, the epigastric pain;
• in the epithelium - up to exfoliative dermatitis, visceral and minor pathologies;
• v sectional system- to the lack of nirkove function, oliguria, proteinurii, waste libido;
• іnshih - to angioedema laryngeal swelling, anaphylactoid reactions, court.

With the best signs of development neobzhanikh effects vicoristannya enalaprilatom slid prizupiniti.

Enalaprilat and Enalapril - why is the difference?

Unimportant to the similarity in names, the names of Enalaprilat cannot be called synonyms.

1. The offense to the drug is called ACE blockers, ale proliks, yak, as a result of metabolism, an active metabolite is established - vlasne, Enalaprilat. Tobto one zasib є yak bi in front of the offensive.
2. Introduced by enalaprilat can only be done internally at the viglyad іn'єktsії, oskіlki, accepting in the middle, wіll become inactive і nasty absorbed.
3. Enalapril, navpaki, small tablet form, may even be absorbed 60% through the intestinal tract.
4. Enalapril signs for a normal reception with a correction of an arterial vise, and Enalaprilat vikorystovuyutsya in non-descriptive vipads.

For the development of drugs, the pharmacological names Enalapril and Enalaprilat are given. The recipe for Latin language first spelled yak Enalaprilum, and the other - Enalaprilatum.

Enalapril is an antihypertensive for a group of ingibitors of an angiotensin converting enzyme.

Mechanism of polyagus in ingibuvanny enzyme (ACE) Enalapril, as a result of reducing the biosynthesis of angiotepsin II to produce vasodilatation, viroblain PGE2 and bradykinin, which cause painful vessels.

In patients with heart deficiency with a trivial reception (6 months or more), the increase in the portability of the heart of the physical age, the change in the size of the heart, the increase in summer

On the way to Enalapril, there is little blood circulation, the grip in the Legendary capillaries goes down, the OPSS goes down, the heart wikid goes down (the heart rate is not growing at all).

Volodya is a deyakim diuretic effect. Change in internal glomerular hypertension, with the development of glomerulosclerosis and risk of development of glomerulosclerosis.

Diyucha speech: enalapril;

1 tablet to take revenge on enalapril maleate (in a pererakhunku 100% rechovina) 5 mg, 10 mg or 20 mg;

Additional words: lactose monohydrate, corn starch, corn starch, povidon, calcium stearate.

Shown to sucking

Where do you help Enalapril? I mean the drug in offensive drops:

• hypertensive ailment 1 or 2 steps;
• nirkova hypertension in cases of sclerotherapy of nirkova parenchyma and sudin;
• sensitive types of hypertensive ailments;
• chronic heart-vascular deficiency;
• vasomotor arterial hypertension;
• inheritance of myocardial infarction.

Under what grip to take? Enalapril priznachayut in case of an advanced arterial grip with renovacusular arterial hypertension. It is also a vicorist preparation for a complex combined treatment chronic heart failure.

Instructions for the administration of Enalapril, administration

Tablets are suitable for oral administration. Oh, take it all, do not rozzhoyuyut і drink plenty of water.

• Pochatkova, the standard dose is 2.5 mg 2 times a day.
• The average dosage is 10-20 mg per dose, and it is split into 2 doses.

In case of asymptomatic deterioration of the function of the myocardial slurry, it is recommended to set the dose - 1 tablet of Enalapril 5 mg per dob, divided into two pills of 2.5 mg each.

The pochatkova dose for renovascular hypertension is 2.5-5 mg / dob. In case of arterial hypertension in important forms, it is permissible to administer the drug internally in the patient's mind.

The maximum dose is 40 mg / dob.

The course of lіkuvannya is trivial є trivial, in some children. Correction of the appointment and appointment of the course of therapy should be started by the doctor individually.

Instructions on the storage of Enalapril Hexal

The drug is implanted directly from the reception of the patient.

With arterial hypertension, take Enalapril Hexal 5 mg vrance. The acceptable dose is 10 mg. Do not take more than 40 mg of the drug for a supplement.

In case of chronic heart failure, take 2.5 mg of the drug vrance. The acceptable dose is 5-10 mg. Do not take more than 20 mg of the drug for a supplement.

In case of dysfunction of the livochka, take Enalapril Hexal 2.5 mg \ 2 times for doba. An acceptable dose should be set to 10 mg twice per dose.

In case of damage to robots, nirok implant 2.5 mg per doba. Acceptable dose: 5-10 mg. Maximum dose: 20 mg per day.

Vicious Effects

It is clear from the instructions from the stipulation of Enalapril that you can supervise the next side effects:

• On the side of the heart-vascular system: overwhelming decrease in AT, orthostatic collapse, chest pain, angina pectoris, myocardial infarction (acutely associated with a decrease in AT), arrhythmias - anterior Legendary artery.
• Three sides nervous system: Spoiled, obscene, head b_l, Weakness, sleeplessness, paresthesia, anxiety, depression, confusion of symptoms, dyspepsia, drowsiness (2-3%), even more rarely in high doses - nervousness, depression, paresthesia.
• On the side of the organs there is a feeling: damage to the vestibular apparatus, damage to hearing and sound, noise in the ears.
• On the side of the herbal system: dryness in the mouth, decreased appetite, dyspeptic problems (nudota, diarrhea, or constipation, bloating, beating in the stomach), intestinal imperfection, Pancreatitis, impaired function of the liver and gum disease, hepatitis, gum disease.
• Three sides mental systems: Unproductive "dry" cough, interstitial pneumonitis, bronchospasm, retardation, rhinorrhea, pharyngitis.
• Allergic reactions: shkirny visip, angioedema of the face, symptoms, lips, tongue, vocal line and / or larynx, dysphonia, exfoliative dermatitis, multiforme toxudative sterile syndrome (including jaundice syndrome) , chickweed (pemphigus), itchy skin, Kropivyanka, photosensitivity, serositis, vasculitis, myositis, arthralgia, arthritis, stomatitis, glossitis.
• On the side of laboratory indicators: hypercreatinenemia, hypotension, hypertension, hypertension, hypertension, hypertension, hypertension, hypertension, hypertension autoimmune disease), Eosinophilia.
• On the side of the secular system: impaired function of nirok, proteinuria.
• Іnshi: alopecia, lower libido, "melt" blood to the surface.

Prototype

The prototype is shown for the sign of Enalapril in offensive drops:

• quay Kvinke;
• stenosis of the nirkovy arteries; hypercalm;
• vagіtnіst;
• sensitivity has been adjusted to the preparation and similar words.

The effectiveness of Enalapril for children has not been established, so it is not recommended for children to sign it in a child's life. For the treatment of patients with such illnesses, the drug is stagnant with great protection:

• autoimmune disease;
• Diabetes mellitus;
• deterioration of the function of the liver;
• aortic stenosis (in important forms);
• subaortic muscular stenosis;
• hypertrophic cardiomyopathy.

Overdose

An overdose of the drug Enalapril is prone to manifest hypotensiveness (stronger depression).

Likuvalny come in:

• transfer of ailing people to horizontal position s omitting uzgoliv'yam;
• washing the slunk with a probe;
• zasosuvannya enterosorbent;
• vidshkoduvannya BCC with a range of 0.9% sodium chloride;
• for indications - infusion to angiotensin II, value of creatine, calories, blood, control / correction of life important functions, Electrolyte imbalance.

If necessary, hemodialis.

Analogues of Enalapril, price in pharmacies

If necessary, replace Enalapril with an analogue according to the ATC code - the drug:

1. Bagopril,
2. Berlipril ®,
3. invorio,
4. renitek,
5. Ednit,
6. NOLIPREL,
7. Lozap.

Vibrating analogs are important to reason, but the instructions for storing Enalapril, the price and advice on drugs of a similar type do not expand. It is important to take into account the consultation of the doctor and not to change the drug on its own.

Price in Russian pharmacies: Enalapril 5 mg tablets 20 pcs. - from 10 to 12 rubles, 20 mg 20 pcs. - 17 rubles.

Zberigati in dry, inaccessible for children at temperatures + 15 ... + 25 ° C. Term of accessibility - 3 rocks. In pharmacies, a prescription is available.

Enalapril, instructions on how to take revenge on the drug, in an effective and safe way.

The drug is available for a prescription.

From the instructions for the administration of Enalapril liquor - tse tablets, which may biliy kolir and a mess of configuration. One side of the tablet is є risk. Vona allows you to easily and accurately disassemble the disk navpil.

Falsely from the number of active speeches of Enalapril, until the end of the period of being a Fakhivite, it is divided into:

• Enalapril tablets 5 mg;
• Enalapril 10 mg
• 20 mg.

Instruction Enalapril has two types of warehouses:

• speech is active;
• additional components.

Table 1. Enalapril (the warehouse for the preparation is given according to the instructions for storage)

Yak viglyadayut tablets Enalapril, from what to help, it is prescribed in the instructions for storing.

Mechanism of Diya

Bagatokh hvilyu food about those, through the words to the lines. The drug Enalapril will lower the grip after about 15-40 minutes. Instructions on how to get rid of it, so that the most amount of food in the blood will appear in 3-6 years.

Table 2. Mechanism of the Enalaprilu department

In such a rank, it is possible to create a knot, for which Enalapril is the result of yogo zasosuvannya. Zavdyak drug:

• the judges expand;
• arterial vise decrease;
• heart rhythm do not go wrong;
• new m'yazov fabrics heart (to produce zokrema until hypertrophy regresses), etc.

Where do you help?

For more information about the idea of ​​\ u200b \ u200bthe enalapril and all the supplementary help, get acquainted with the information about those

Tablets are readily prescribed from instructions for use when:

• a regular vise on other reasons ponad 140-90 mm. mercury stock;
• in the quality of pharmacological treatment a number of heart ailments;
• for the prevention of the development of sickness of the heart / sudin, with a lethal result.

Enalapril, the dose of what kind of vykhodyachya is diagnosed, it is recognized viklyuchno fakhivts.

Shown to sucking

Establishment of an accurate diagnosis є by the hindrance of a successful treatment. Enalapril, shown before the registration of what is prescribed in the instructions, recommendations for:

1. Arterial hypertension. Enalapril (the recipe can be revised from a licor) is effective in the case of the first form of illness, vicious systemic damage, and regulates the grip. It is also recognized with secondary hypertension, which has become a legacy of other pathologies. Instructions for storing a single meaning, which is effective in case of renovascular hypertension.
2. Essential. The form of hypertension is special, characteristic feature which є visnazhennya nirkovo depressor function.
3. Chronic SN. Enalapril (instructions for the preparation of tablets are recommended to be included before the warehouse of the complex treatment) is effective in case of damage to the robotic chambers of the heart.
4. Conducted prophylaxis of heart failure and actions.

A new dash of information about those for Enalapril tablets, for example, is recommended in some vypads, є instructions.

Annotation Enalapril will not be pummeled with a vise to optimally accept the drug. Lykarskiy should drink regularly, and not all the way to the last. enalapril ( pharmacological group-), nadaє cardioprotective infusion only with course designation.

The most widespread causes of hypertension

Prototype

Uninvolved in the safety of the liquids, it’s safe to use the instructions because of the storage of the children’s children. Enalapril, the contraindication to how much to reach the big, is not recommended for:

• anaphylactic shock in history;
• arterial stenosis on one / both sides;
• excess calories in the organism:
• different forms of porphyry;
• allergy to components;
• sleeping with aliskeren;
• nirkovoj / pechinkovoi deficiencies and in.

The entire list is indicated in the instructions for storing.

Instructions for storing

Form of vipusku Enalapril, dosuvannya, hour of day and especially for the reception of information in the instructions for storing. You can also take revenge on the information about the children in the categories of children, which may be supplemented by the following:

1. Children and children. For this category of dosage, you can be safe and secure from every day. Up to 18 years, the drug does not stagnate.
2. Lіtnі people. Likuvannya of children 60-65 years of special protection. The first priyom is recommended to spend in the minds of the stationary.

Piti varto in the rank of year, not meaningful until after the day. Enalapril 5 mg Instructions for use is recommended to take 1 tablet on cob stages. For some people, the dose will speed up to 2.5 mg (for young people, patients with damaged robots, etc.). Middle dobova dose get 10 or 20 mg

For an extreme reduction in the vice vikoristovuєtsya zasіb in ampoules. Introduce 1.25 mg of skin for 6 years. For therapy with diuretics, in case of swelling impairments of the function, the dose is changed to 0.625 mg.

For his sutta, there is only one Trade name the drug. Chim return to Hexal:

1. Rizni virobniki. Daniy zasib vipuskak company "Hexal", which is located in Nimechchin, and the other drug is the Russian company. "There are only one thoughts about those who are more beautiful, dumb." The offense brands have recommended themselves from a positive side.
2. Technologies. Get ready to wriggle around for different technical minds and on a daily basis.
3. Warehouse. international name Identically, when both are prepared, enalaprilu maleate is used as a vicorist. However, vyrobniki zastosovuyt ізні additional speeches.

It's more beautiful, Enalapril or Hexal, say it well. Pharmacodynamics and pharmacokinetics of both drugs are similar, so the stench is mutually beneficial.

Give є analogs і may іnіdentichnі shown before zasosuvannya. Viroblyayutsya by small companies. The drug Akri is available in Russia by the company Akrihin.

The recipe for Enalapril in Latin is the same for both of them, but for additional speeches, they can be readily developed. Before the reception, it is recommended to familiarize yourself with the instructions and costs.

Leaks are carried out by the Moscow pharmaceutical enterprise "Obolenskiy". Warehouse and for preparation of identical preparations. FPO is similar in that, if you start to fix it, in some cases, if you need to take pills, if you need to take a pill to protect it. It’s possible to substitute for the FPO without a fight.

recommended for sliding grip and heart failure. It is a vinyatka transmutation of pre-existing speeches. To be accepted to the APF іngіbіtorіv and you can fix it within the framework complex therapy So and with monotherapy. maє identity pobichna diyaі recommendations for storing.

To be considered for complex therapy preparations. It includes two active ingredients at once: the ACE inhibitor enalaprilu maleate and the diuretic hydrochlorothiazide. Recommended in quiet cases, if monotherapy is not supplemented. Effectively I reduce the grip of winding during the bends of arterial hypertension.

It is dispensed in a dose of 10 mg. Stagnate yak for lowering the vice, likewise and prevention of heart failure. Effectively the speed of the number of hospitalizations at unstable angina, Rizik of a lethal result in the form of heart disease.

It is allowed to use the form in the form, which allows the preparation of the drug in extraneous form. Shvidko reduce the grip of a risk of a hypertensive crisis. Vikoristovuєtsya viklyuchno lykar shvidkoy help or within the framework of the stationary. Uncontrolled іn'ktsії can become the reason for the accelerated death of the patient.

virobnik lykarsky zasobuє Indian company. The drug is available in tablet form in doses of 2.5, 10, 20, as well as 5 mg (shown before filling for all forms can be read in the abstract).

The drug, which reduces the vice, revenge 20 mg of active speech. Dіє after 15 hviliin go to the reception. The maximum concentration in the blood appears in 3-6 years. With the correct dosage, the hypotensive effect will last for 24 years. Before storing it is recommended to get acquainted with the instructions for storing.

A single therapeutic effect and a similar warehouse allow you to respect a lot of synonyms. Їх take:

1. Additional speeches. Enap has a number of other components that can be used to remove the necessary consistency and physical and chemical characteristics.
2. Virobniks. Enap is carried out in Slovakia and is considered to be in high order from falsification.
3. Price. Enap kostuє more expensive than analog in 2-3 times.

It's Christmastide day abo po special vipad Good people want to drink a drink. Patients hvilyu food about the madness of the drink with alcohol, the legacy of which you don’t expect to be transferred. Readily from the instructions from the feeder:

1. Alcohol provokuє overmіrne lower grip. Living in a dormitory may be the reason low indicators AT. This may not be safe for health and life.
2. The drug should be prepared with alcohol until the toxic ethanol is added.

with vaginosti

Enalapril with vaginosti is even more insecure. Wine to produce until the growth and development of the fetus is damaged. In case of vaginosity in early terms, when the sign of kostya appears, it is inaccurate to pin it on. For women who are planning to conceive, how to blame a child or a breast, a preparation of fences.

Pobichna diya

The instructions for the administration will describe a number of negative phenomena, which can be used as a result of taking pills.

Table 3. Subsequent effects of Enalaprilu

Chi pouring into the potency?

Decrease in sexual urge to be included in the list of junior side effects. However, when you talk about cholovikiv, it is reported that the ACE Ingibitories will support the production of cholovic hormones, which will reduce the potency. In any case, the therapy of arterial hypertension is not at all sensed. Chomu axis:

• by itself to produce up to the point of being able to get rid of the buzzing of the vertebral organs and the deficiency of the blood supply of the organs;
• it is also very much more risky of raptor death.

cholovika z arterial hypertension it is not only the food that is guilty of those who infused the drug on the potency, but the importance of the therapy. Without proper lіkuvannya cholovіch strength will weaken, and the risk of lethal result will be colossal.

Preparations that can be applied to the group of ingibitors in angiotensin converting enzyme have become widely used in medical practice for 40 years, until the whole day, only from the most effective participation for fighting arterial hypertension. The representative of the group - Enalapril - is widely victorious. Instructions for storing Enalapril include a lecture description of the demonstration, prototype, method of storing leads, its side effects and peculiarities of the victorian.

Description and key authorities

Enalapril is administered in the form of tablets for oral administration. The names of the tablets may be bili or siruvate vidtinok, dispensed in doses of 5, 10 and 20 mg. Pack up in blister. The cardboard packaging has 2-3 plates.

The head of the drug is enalapril maleate. The concentration of this in one tablet is deposited as a form virobnitva, becoming 0.005, 0.01 and 0.02 g, apparently.

Shown before recognition

Instructions for storing Enalapril include finishing the show to the victorian. Explained by the specific and by the strong dyєu of the faces, as well as by the great list of side effects and prototypes.

In medical practice, the lykarskiy is able to recognize the patients with the following conditions:

• developmental stages of hypertensive heart ailments. The strength of the drug is to correct the reduction in a way, or to increase the dosage individually for the skin patient;
• arterial hypertension developmental ethology... Bagatorial dosvid show, but Enalapril itself є with one of the most effective assists in the sphere of struggle with a strong grip;
• chronic heart failure, as well as important forms of pathology, sprout, during the renewal of myocardial infarction transferred to renew the function of the heart;
• heart failure, which is supervised by stagnant processes;
• Enalapril vicoristovuyut in the capacity of complex treatment for bronchospastic camps;
• lіkuvannya dysfunction lіvіnі sluchnochka, іtіkає in latent form;
• ІХС, which is supervised by attacks of angina pectoris and іnshiye manifestations.

How to secure

Yak accept Enalapril? Tablets are suitable for oral administration, to be implanted in the middle. The drug should be washed down only with pure water, so as in union with juices, chaєm, kava and інshim drinks for an hour, yes a negative effect.

To achieve a better result, the tablet is allowed to be applied to the tongue, trimati, until re-distribution. We are ailing in the case of hypertensive crisis for a quick decrease in the arterial grip.

Through skіlki dіє zіb

The therapeutic effect of the intake of Enalaprilu is infused after approximately 60 minutes after receiving. The most significant concentration of the active ingredient in the drug in the blood is indicated during the period.

The triviality of a hypotensive child becomes close to 24 years old. It takes an hour for the drug to take place in patients with heart deficiency, as well as in ailments due to diseases of the heart and liver.

Feel free to live with a double reception. In a large dose of pochatka, the dose should be 5 mg, it should be adjusted step by step with good tolerance of the cat.

Skіlki dіє medication zіb? The period for the time being shall be up to 5 years. Pislya tsyogo diya Enalaprilu should be lowered.

make up for likuvalny effect the drug with a one-hour vikorystannі with antagonists of calcium and thiazidnimidіuretics.

Skіls developed for doba

The number of admissions and follow-ups will be initiated by the Provider based on the patient's history and scarg. Play in the role of monotherapy Enalapril is prescribed for 10-20 mg of two per dose.

In case of a complex drug addiction, I will prescribe 1 tablet at a time in the evening. The triviality of treatment is individual for a skin ailment.

Take it before you go

Instructions on the use of Enalapril N and the other brands of liquids do not prescribe clear tablets before taking pills. The drug can be drunk before taking it, as well as when it is received. It is practically not infused with the therapeutic effect of kosti.

With a grip

Bagato patsієntіv tsіkavlyatsya, with any grip of the drug? Stagnation of Enalaprilu is shown by patients with a slight increase in arterial vise on aphids, as in the case of a disturbed blood circulation in the brain and heart.

In case of hypertensive ailments, Enalapril is recommended to be recommended in case of increased indicators of a mercury stock of more than 120/90.

It’s like the working grip of the people becomes 100/60;

supplementing the drug

Annotation to Enaloprilu inform about those who take it before, or even if the hour is in advance, designated by the doctor in the presence of the diagnosed diagnosis. Likuvannya for an additional drug is carried out both in the role of self-contained and complex therapy.

self-therapy

On the cob stages of lykuvannya, we are sick, prizvichayut ¼ tablets of 20 mg. Even with a stretch of 7-14 dB, the effect of the daytime and the grip does not decrease to normal views, while it gradually increases. With a full dose of dobova, the dose is not guilty of overvischuvati 40 mg of koshti.

complex lykuvannya

In case of elimination of heart deficiencies and those of them, in the role of complex therapy, Enalapril is prescribed 2.5 mg once for additional purposes. Proceedingly, the dosage will increase, but not more than 2-2.5 mg once every 7 days.

If there is a lack of heart of the chronic nature, the dosage should be set on the first stages of 2.5 mg. The rate is changing step by step, 1 time per day for 2-2.5 mg.

In case of hypertension Renovascular type of denna, the norm of lykarsky zasoba cannot be increased to 20 mg. On the cob stage of the ailing indications, take ¼ two tablets on the side of the dob.

Consistency with alcohol

Take Enalapril and alcohol is hardened in any doses. Such an effect can be caused by a number of important accelerations that are not safe for the health and life of the sick. On the right, in that, on the smallest of alcoholic beverages, you can do some medication, which will lead to an important form of arterial hypotonia.

The confusion of Enalapril and alcohol in the region is not suitable for the patients who suffer from the sickness of the little ones and the stoves. Prior to negative inheritance, there is a stiffness of hypotension, damage from the side of the central nervous, dichal, heart-vascular system.

It’s a good idea to promote the development and intensity of the potential side effects of the household. The patient can get stuck with severe headaches, tediousness, dullness and minor symptoms.

In case of damaged functions of nirok

In case of important pathologies, the drug has more contraindications. Vikoristannya zasobu can bring to the inconvenient acceleration, to the incredible lives.

In case of dysfunction, the body is allowed to consume Enalapril in a cob dose of 2.5 mg per dose. The maximum amount of liquor is not guilty of changing 20 mg throughout the day.

In case of dysfunction swelling, a sick person should be given a dose of 2.5 mg per day, for example, if the amount of liquor does not change, 10 mg is permissible.

With the sound of the nirkovo artery of one-sided or two-sided nature, Enalapril does not stagnate.

When the function of the liver is damaged

Zagvoryuvannya pechіnki є direct contraindications to victorian Enalaprilu. In the region of rіdkіsnyh vypadki fakhіvets can take a decision about the appointment of the drug in intermittent doses, even if medications for do not give a necessary benefit.

Significance in Lithuanian

The patients in the summer trip will be grateful to the stationary's minds. At the same time, control over the dynamics of indicators of arterial vise, analysis of blood and blood is carried out.

Primary dosage for patients aged 65 years is guilty of holding 2.5 mg. In addition, a dose of not more than 10 mg must be allowed.

Vikoristannya with vaginosis and lactation

Instructions on how to talk about those who, during the period of the child's marriage and the breastfeeding treatment of Enalapril, are strictly contraindicated. If you need to take the drug all the time, babies of such mothers are guilty of being under medical supervision, regularly submit analyzes.

Inflow to the building of keruvati by folding mechanisms

Patients who pass the trip with the help of Enalapril, follow the security of the message labor activity, Scho vimagaє increased concentration of respect, shy psychic and physical reactions. In some cases, there are a lot of possible development of individual reactions to the body, sprout, when taking large doses, after drinking alcohol.

Appreciation in a childish vice

Danikh about the safety of the drug in the middle of children up to 18 years of age, so in pediatrics we can only use vikoristovyu if there is a great need for extraordinary situations.

lykarska vzaєmodiya

Included in the recipe for Enalapril, Fakhivets is guilty of the general relationship with the other drugs:

• to change the hypotensive dyu of the drug when it is combined with analgesic drugs, non-steroidal anti-inflammatory drugs;
• in an alliance with sechoginnym pigulki sudinorozshiruvalnuyu enalaprilu will do;
• Vitamin complexes, which include kaliy, kaliyzberigayuchi diuretics, in case of an one-hour consumption of Enalapril, cause the threat of an excess of calories in the body - hypercalm;
• it is very important to include sodium chloride, to change the hypotensive drug;
• to accept antihypertensive action when using drugs for anesthesia;
• in case of implantation of medications, to take revenge on insulin, on aphids of Enalaprilu їkh hypoglycemic action will be accepted;
• registered vip leukopenia in case of a diagnosis of cytostatics, immunosuppressants, and hormones.

Umovi zberigannya and sale from pharmacies

When buying Enalapril in a pharmacy, it is necessary to present a prescription. The collection of liquids is required in children abducted by children at temperatures not exceeding 25 degrees. Termіn zberіgannya at the moment of virobnitstva - 3 rock. It is categorically not recommended for the end of the period to be victorious.

Vikoristannya Bisoprololu with hypertension

Bisoprolol is a selective β-adrenergic blocker - it is used as a drug in 1967, and on the other hand, on the other hand, there is a high selectivity (vibrating) and power injected. Likuvannya of hypertension or angina pectoris with a drug, we have a problem with overexposure.

With a partial analysis of the injection of Bisoprolol and analogous β-blockers, the stench was equally quickly reduced the arterial vise. Alle, with the additional monitoring, it was found that only Bisoprolol was taken as indicators of the onset of the wound. At the same time, the normalization of the arterial vise indicators was not only in the spoky stanі, but in the case of navantazhennyah. Stiffness and equipoise infusion of one-single pills by pulling out the add have made bisoprolol deserved popularity.

Pharmacology Bisoprolol - mechanism of action

Hypotensive (lower arterial grip), antiarrhythmic (normal heart rhythm) and antianginal (decreased symptoms ischemic ailments) Efekti. The therapeutic dose is not volodya internal symptomatic activity and insignificant membrane stabilizing abilities.

For the infusion of minimal doses of the drug (active speech - bisoprolol fumarate):

In the case of the increase in dose, which significantly changes the norm (in 0.2 g), as indicated in the abstract, the drug can cause the blockade of β 2 -adrenergic receptors in the bronchial tubes and smooth mucous membranes of the vessels of the nerves. Immediately, the hearty wikid will speed up.

The therapeutic dose is not a cardiodepressive infusion, it is not infused with glucose absorbed by the body, and it cannot be absorbed by sodium. The maximum effect will appear after 1-3 years or after implantation and take 24 years.

With blood molecules the active component is bound by 30%. In deyakіy world Bisoprolol fumarate can penetrate through the placenta of the fetus. Partially eat milk in your breast.

Form a vipusk drug

Photos: to improve the clicks on the description of the forms of release.

Pharmacokinetics: warehouse і principle of dії

Bisoprolol dermal tablet includes 0.005 or 0.01 g bisoprolol fumarate and napovnuvach in viglyadi stearate magnesium, silicon dioxide, crospovidone, crumble and cellulose. The Bisoprolol preparation has a casing warehouse, where the capsule is wrapped, - alcohol, macrogol, talc, titanium dioxide and a little bit of zhovtikh barvnikiv.

Bisoprolol is dispensed from round beige and soft tablets of 20.30 or 50 pieces in a skin pack.

The drug is absorbed by 90% is not stale, half of it is transformed into a liver, 98% is absorbed by nirkas, the surplus is absorbed.

Bisoprolol: indicated before consumption

Bisoprolol tablets: what kind of stench really help? Between the wider displays:

• Hypertonia (steely high arterial vise);
• Angina pectoris (IXC);
• Sertseva lack (in a combined version with other medicines).

Bisoprolol is especially respectful to use:

1. With psoriasis and all those who have ailments in their homeland with the diagnosis "lichen lichen".
2. With sugar diabetes (stage of decompensation).
3. I am smart to allergy.
4. We are sick, some professions are tied with a high speed of reaction, so that they can clog their health. At the first stage, the speed of reaction decreases. An analogous effect is promoted by injecting alcohol, as in the drug Bisoprolol and alcohol the madness of the rotten.

We are sick with the diagnosis of "pheochromocytoma". Bisoprolol is recognized when the course of therapy with α-adrenergic blockers is completed.

Bisoprolol for vaginosis

Do not recommend a medication for zagalny vipadku for vagіtnyh or age-old mothers. The win can be found in the situation, if the effectiveness of Bisoprolol for the mother is transferring the ribs for the child. As long as you are still able to undergo a course of therapy with Bisoprolol, you can skate not less than three dib to flat.

In case of nedotrimanny cієї, wash out the new-born risiku to add a bouquet of ailments - hypotonia, hypotension, bradycardia, hypoxia. Yakshcho skasuvati Bisoprolol does not allow health, the camp of the new-born stretching of the first life needs to be controlled permanently.

Prototype display to validation

Bisoprolol is not recognized, as the patient is suffering:

• Hypersensitivity to any kind of input to the warehouse;
• guest abo chronic form heart pathology, if to carry out inotropic therapy;
• Shock cardiogenic character;
• Weakening of the sinus node;
• Newcomers in Legends;
• Sinoatrіalnoї blockade;
• An important bradycardia;
• AV blockade 2 і 3 tbsp;
• An important stage of arterial hypertension with the boundaries of the systolic arterial vise up to 100 mm Hg. Art.;
• uncompensated for diabet;
• Pheochromocytoma (parallel to the prescription of α-adrenoblockers);
• Bronchial asthma in important forms;
• Metabolic acidosis;
• Damage to peripheral blood flow;
• Refractory gipokaliyєmієyu, hypertsaltsіemіyu or gіponatrієmієyu;
• hypolactasia;
• Lactose deficiency (lactose in the warehouse).

No follow-up of the effectiveness of the tests was carried out for the patients of an incomplete veterinarian. If we do not get sick, we do not have a prescription for a course of therapy with MAO inhibitors (for the blame of parallel immobilization with B-type monoaminoxidase inhibitors).

side inheritance

Zasib Bisoprolol: what needs to be taken away from? In the abstract, the statements and actions should be shown in front of the eye:

• Headache and impaired coordination;
• Vidchuttya vtomi, when there is a lack of strength;
• Risky rush of blood to the head, provoking;
• sleeplessness;
• Disorder of the psyche of the depressive and hallucinogenic type;
• Paresthesia of hands and nig, seeing cold colors;
• Decreased secretion of slavic vines;
• Conjunctivitis develop;
• Pain in the abdominal area, tediousness and vomiting;
• Rozladi robotic intestines;
• Myazovoi weakness;
• Frequent trial;
• Orthostatichypotensive;
• Signs of bronchial obstruction (in case of manifestation of schism);
• Strong potovіlennya;
• Dear Sertsebitty;
• Rozladi AV-Providnost.

You can change the tolerance to glucose (most often - in patients with a diagnosis of "diabetic diabetes", including the pretense of their form, as you do not show yourself). zasib yes positive reaction on doping control. Bisoprolol has a side effect manifested in ridkisnyh vypadki, instructions are delayed, first for everything, physicians, to clarify dosage and confusion.

Bisoprolol: instructions for administration

Some indications for oral implantation. Accept yogo vrance, until the end of the day, or until the hour of the day. Drink it whole and wash it down with water. Dobova's norm for a grown-up person is 20 mg. yaksho special requests Not bulo, patients-hypertensives, or we have a problem with angina pectoris, 10 mg of the drug for a one-time implantation is sufficient.

On the very cob, the course can be interrupted with a larger dose of 5 mg / day. It is possible to change the norm in the most extreme way. In case of higher additional norms, the rules will be taken into account. The standard scheme of therapy with Bisoprolol tablets according to the instructions is presented in the table.

An individual scheme of treatment is established by the therapist, looking at the indicators of the pulse and reaction to the body. We are sick with insignificant dysfunction of nirok, nirnirniki or liver, and also adults do not need a dose of coriguvati. In case of important forms of re-insured pathologies I will add the norm mix 10 mg of the preparation. Likas rozrahovano on the trivial stasosuvannya. Would the drug really help control the grip on the arms of the rock?

Bisoprolol is used in many pharmaceutical enterprises, but not injected into the scheme of storing the drugs. Bisoprolol-Prana has the same instructions as the analogs of the Luhansk CPP or the Israeli company Teva.

Overdose

Overdose is manifested in viglyad:

• Yaskravo bradycardia;
• arrhythmias;
• Extrasystoles of the shlunochka;
• AV blockade;
• Significant fall of the arterial grip;
• Heart failure;
• Cyanosis (blue) hands;
• zadishki;
• zamorochennya;
• bronchospasm;
• Syncopal stan_v;
• Sudomnikh attacks.

In case of drug overdose, the slurry should be washed, adsorbent drugs and symptomatic therapy should be prescribed:

1. Atropin or adrenaline (1-2 g intravenously) with AV block. One problem is solved by installing a pacemaker.
2. With the extrasystole of the shlunochka - lidokain (internally). At the same time, do not vikoristovuyt medication IA class.
3. When the arterial grip of the patient falls, move to the Trendelenburg position (the head and shoulders are 30-45º lower than the pelvic ridge).
4. Plasma-free solutions should be injected at the vein, as long as the symptoms do not appear. Chi is not about the lack of efficiency in the case of a general drop of AT to add adrenaline, dobutamine.
5. Heart glucosides, diuretics, glucagon.
6. Diazepam is administered into a vein to stop suicide attacks.
7. Inhalation of β-adrenostimulants for bronchial spasm.

It’s important to take Bisoprolol, not only to get instructions, but to do it with the doctor.

Bisoprolol is absolutely insane with floctaphenin and sultoprid. We do not recommend combining it with calcium antagonists, antihypertensive drugs, and MAO inhibitors. Carefully slide along Bisoprolol and preparations:

• Anti arrhythmia;
• Antagonism of calcium;
• Anticholinesterases in the case of β-blockers for local infusion;
• Preparations based on insulin and insulin for diabetics;
• β-sympathomimetics, healthy activity of α- and β-adrenergic receptors;
• Heart glucosidi (based on foxglove);
• Come to ergotamin;
• Succeed for zelenuvannya;
• Protistopalny non-steroidal liquors;
• Antihypertensive medications, which improve the hypotonia (antidepressant, barbiturati);
• baclofen;
• amifostine;
• Parasympathomimetics.

Apparently normal interaction of Bisoprolol with Meflochin and corticosteroids.

Mind the sale and purchase

Bisoprolol, liquids, sold in pharmacies only for a prescription, vipisanim in Latin: “Rp.: Tab. Bisoprololi 0.005 # 20. D.S. 1 tab. per day (АГ, ІХС) ".

At the same time, for any representative of Bisoprolol, instructions on the cost of the drug from the skin virobnik have its own: for example, Bisoprolol-ratiopharm (0.005 g) in Russian pharmacies can be bought for 350 rubles.

The drug is added to the class B. Zberigati is recommended at temperatures up to 25 ° C in the drains of dry and dark priming, which is not available to children. The term of a baked-on storage is 36 ms.

Bisoprolol analogues

Before structural analogs to Bisoprolol, there are medications Bisogamma, Biprol, Bisoprolol-Prana, Niperten, Bisoprolol-ratiopharm, Bisoprolol-Teva, Bisoprolol-Lugal, Concor, Bisomard, Concor,

Analogous mechanism of drug administration may be for the preparation Atenolol, Betalok, Betacard, Nebilet, Binelol, LOCRENU, Egilok, Metokor, cordanum, Lidalok, Metoprolol, Metozok, Nebivator, Nebilong, OD-Neb.

On the forums, they often discuss food: how are they more beautiful - Bisoprolol or Concor?

Concor is the name of the trade brand, for which the original Bisoprolol is used. Virobnik - the company Merck KGaA from Nimechchin. Unfortunately, the term for the patent for the drug Bisoprolol Concor has already ended, so our market today can create unimpeachable alternative options - generics to Bisoprolol, and get effective alternatives available at a price.

Perevagi Bisoprolol

In proportion to analogous beta-blockers, Bisoprolol has a number of reversals:

1. For effective control of the grip, 1 tablet of the drug is enough to add - win the activity, both during the day and at night.
2. We are very happy with the implantation of the heart, so it’s just a matter of time.
3. The medication has high selectivity. In the case of β-blockers in the front generation, there is a lesser amount of secondary inheritance.
4. Likki do not scare negative influx on the number of health. The changes in the results of placebo-controlled follow-up were not seen in any control group, as it has been seen.
5. Bisoprolol is metabolically neutral, so it does not overwhelm metabolic processes (cholesterol, triglyceride and glucose in the blood).
6. The drug is available to patients with type 2 diabetes and to representatives of the group for a wide range of problems.
7. Likas are consistently recognized in a mature way, as the value of a side-by-side inflow is less than that of analogs.
8. Pharmaceutical market of re-fills with generics Bisoprolol - analogs, which are widely competing companies. The price of the policy is not only effective, but rather affordable in the financial plan, so as on a piece of liquor, Bisoprolol price is signi fi cantly lower.

Bisoprolol: sick people

On the thematic forums, Bisoprolol is popular. More often for those who negotiate the Bisoprolol tablets, they will see the triviality of the treatment. On a tlі sharp prynennya vzhivannya to the drug in bagatokh vinikє the syndrome of vіdmini.

The main manifestation of this: attack the hypertension, the pulse quickened. For some people with ailments in the period of love, it was poured into a zir. Ale so, the drug is even more trivial, and for someone even more often, then all the symptoms described may be but not due to Bisoprolol implantation. Rizik show the side effects as a whole: some of the corystuvachi didn’t remember the obvious damage, the stench of those stenchs was odd.

You can summarize all the thoughts, you can come to the office, where you can use such a serious drug like Bisoprolol. As far as the dose is not correct, it is possible to correct a bunch of side effects, right up to the heart. Appointing, the scheme of treatment and the hour of administration of the drug is guilty, but only in the competence of physicians.

Information is designated for physicians and students of medical universities. Do not indulge in self-abuse, for a qualified auxiliary, turn to a lykar.

Prescription for rozchin enalapril (enap) in ampoules in latin

Prescription for enalapril (enap) in latin tablets

Headquarters:

Diyucha speech: Enalapril (INN)

Pharmacological group: Angibitori ACE

Prescription form: N 107-1 / y

With the protection of stasis for the children due to the reduced function of nirok and stove. It is forbidden to receive an hour of vaginosti and lactation.

Enalapril - instructions for storing, analogs, guides, prices

Enalapril drug

formy vipusku

Instructions for storing Enalapril

Shown to sucking

2. Secondary arterial hypertension in the presence of ailments nirok.

3. Chronic heart failure and asymptomatic dysfunction of the louse (as part of the combined treatment).

Prototype

• Revealed in the last angio-neurotic dummy, including those who received Enalapril and others іngіbіtorіv APF;
• Porphyry;
• vagіtnіst;
• lactation;
• Sensitivity has been adjusted to the preparations given to the class.

At the connection with the risik of a sharp decrease in the grip of the protection, the drug is indicated for decompensated forms of ІХС, with bilateral stenosis of the nirkovy arteries, stenosis of the arteries of the single nirka, cerebrovascular congestions, if

Pobichna diya

Also, there is a data about the diagnosis of a complex of symptoms: increased temperature, vasculitis, malgia or myositis.

lykuvannya Enalaprilom

Apparently, prior to the appointment of a drug, the drug should be taken 1-2 times per day, regardless of the intake. Combined drugs Enalapril, which is to avenge sechoginni, is more beautiful than vrance. Lіkuvannya drug otrimuyut trivialo, with good tolerance - stretching out life.

In case of arterial hypertension, fix it at a dose of 5 mg / day. In case of lack of effect, the dose is increased to 10 or 20 mg - 1-2 r / day. Maximum priznachayut 40 mg 2 r / dobu.

Vzamodiya Enalaprilu with other drugs

analogues of Enalapril

Combined preparations, such as Slovenian Enap H і Enap HL, Russian Enapharm H і і їм podibnі. Krim Enalaprilu, and the drug should take revenge on Gidrochlorothiazide, which will help to develop a hypotensive effect.

Widgets about the drug

The price of the drug

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enalapril

Description overdue on 10/25/2014

• Latin name: Enalapril
• ATC code C09AA02
• Diyucha speech: Enalapril
• Virobnik: Hexal AG (Nimechchina)

warehouse

Before the warehouse of tablets, there should be included enalapril in the range of 5, 10, 20 mg, as well as additional words: gelatin, lactose monohydrate, magnesium stearate, magnesium carbonate and crospovidone.

Vipusku form

Tablets of 10 pieces per blister, 2 blisters per pack.

Vypuskayutsya by small pharmaceutical companies, for example, to name diyuchy speech the name of the company is added to the name of the drug, for example: Enalapril-Zdorov'ya.

Pharmacological diya

The medicine reduces the grip, expands the blood-bearing vessels, gives cardioprotective and natriyureticheskogo diyu. The drug is added to the group of ingibitors in the angiotensin converting enzyme.

Pharmacological group: Angіbіtori ACE.

Pharmacodynamics and pharmacokinetics

It is worth noting that the abstract mechanism of polyagus in the ingibuvanny enzyme (ACE) Enalapril is used to reduce the biosynthesis of angiotepsin II to vasodilatation, vasodilatation, vasodilatation, vascularization

In patients with heart deficiency with a trivial reception (6 months or more), the increase in the portability of the heart of the physical age, the change in the size of the heart, the increase in summer With each drug, there is little blood flow, the grip in the capillaries decreases, the systemic vascular resistance decreases, the heart rate decreases (the heart rate is not growing).

The moisture content of the drug Enalapril reaches 60% in independence from the reception and appearance of the drug in the intestinal tract. The maximum concentration of active speech in enalaprilat is indicated in 1 year after being deposited. In the oven, it is biotransformed to enalaprilat. Vin is easy to pass through the placenta, gistogematic bar'єri. Vivoditsya nirkami. The hypotensive effect will be restored after 1 year after the introduction of the LZ, it will be easy to add. To achieve optimal results of AT, it is necessary to take a number of regular doses of Enalapril.

Shown up to the suction of Enalaprilu

What are the Enalapril tablets?

Indicated before stasis Enalaprilu onset: hypertensive ailments, Raynaud's ailments, heart failure, symptomatic arterial hypertension, diabetic nephropathy, scleroderma, secondary hyperaldosteronism. Enalapril is recognized at the warehouse for complex therapy in cases of angina pectoris, myocardial infarction, chronic nirkovy deficiency. Zastosovuyut tablets in the vice of a podvischeniy.

Prototype

Hypersensitivity to ACE inflammation, stenosis of the nircoval arteries, azotemia, hyperaldosteronism, hypercalcemia, impaired function of nirok, Quinke swelling (decongestant character), stenosis of the aortic artery, childish vik... Enalapril does not acknowledge the vagina women.

Pobichna diya

The drug has such side effects: malaise, malnutrition, headache, sudomy, nervousness, sleeplessness, soreness, noise in the ears, dry cough, nudity, orthostatic hypotonia, heart disease, dyspepsia rositis hyperkalієmiya, embryo Kvinke, neutropenia, increasing the level of bilirubin in the blood, hair loss, pain in the area of ​​the heart, increased concentration of liver transaminases.

Enalapril tablets

Likas take all the middle. The pochatkova dose should be 5 mg per dobu, the drug should be taken once a day. In case of pathology of the nirkovo system, when taking sechogenic drugs, the dose should be reduced to 2.5 mg. To achieve an effect in the fallowness of individual specialties, the dose of the drug can be increased by DOMGO per day (it can be broken by 2 times).

Instructions on the storage of Enalapril Hexal

The drug is implanted directly from the reception of the patient.

In case of arterial hypertension, take 5 mg of enalapril maleate vrance. The acceptable dose is 10 mg. Do not take more than 40 mg of the drug for a supplement.

In case of chronic heart failure, take 2.5 mg of the drug vrance. The acceptable dose is 5-10 mg. Do not take more than 20 mg of the drug for a supplement.

In case of dysfunction of the livochka, take 2.5 mg of two per dose. An acceptable dose should be set to 10 mg twice per dose.

Yak to take over when the robotic nirok is damaged? In a given situation, they live 2.5 mg per dob. The usual dose is 5-10 mg. The maximum dose is 20 mg per day.

Enalapril Acre Instructions

At any hour. Take a dose of 2.5-5 mg once every 24 years. An acceptable dose should be 10-20 mg every 24 years. The maximum dose is 40 mg for 1-2 doses.

Instructions on Enalapril FPO

It is similar to the method of dosage of the previous preparation.

Scheme for receiving Enalapril N

1-2 tablets once every 24 years

Overdose

Abovemіrne fall of arterial vise, myocardial infarction, cerebrovascular accident, thromboembolic acceleration as the inheritance of a sharp decrease in arterial vise. Lіkuvannya: in / in the introduction of NaCl (izotonic range). There is no specific antidote.

vzaєmodiya

Absorption of the drug does not lie in the reception of the drug. With a one-hour intake with beta-blockers blockers, nitrates, methyldopia, calcium antagonists, prazosin, hydralazine Enalapril has a potential hypotensive effect. Cimetidine Zbilshuє T1 / 2 to the drug. Refinery increased nephrotoxicity, decreased efficiency of Enalaprilu. Calcium preparations and high blood pressure diuretics should be given up to hypercalcium in case of taking from LZ. Enalapril changes the period of time for theophilia, lowering the clearence of the lithium. LZ does not interact with heart glucosides.

Mind the sale

Umovi zberigannya

At a temperature of 25 degrees Celsius in a dry place inaccessible to children.

Term of attachment

Not more than 3 rock_v.

special requests

In the first year, the reception of Enalapril can lead to a swiveling decrease in the arterial grip. It is especially desirable to manifest itself in particular, for the first time to take a hypotensive drug, in patients with chronic nircovy deficiency, severely rotated heart deficiency, hypovolemia, hyponatremia. For the prevention of a sharp decrease in the arterial grip 2-3 days before the reception of Enalapril, take the drug and salt to the dose. With the development of an anioneurotic embryo on the face, it is necessary to determine the diagnosis of the LZ, to identify antihistamines. In important cases, perform intubation, tracheotomy. It is not recommended to immediately take kaliyzberigayuchi diuretics. It is necessary to regularly monitor hemostasis. Enalapril does not acknowledge women who are planning to work.

Likas registered by VOZ according to the view of the associate Vidal.

Often vikorystovuєa with hydrochlorothiazide in combination with.

Recipe in Latin: Tab. Enalaprili 0.01

INN: Enalapril.

analogues of Enalapril

Lisinopril or Enalapril - is it more beautiful?

Lizinopril on delivery has been effective in reducing the arterial grip, as well as for a longer period of time. Transferring offense to the drug is approximately the same.

Enap і Enalapril - what is the difference?

On the basis of the drug, there is nothing to be recognized, since there is only one and the same speech. However, the price of Enap is an analogue.

Enalapril and Enalapril Hexal

The drug is released by the Hexal company, as a matter of fact and there is no further improvement in the name.

Widgets about Enalapril

Widgets of drugs to be produced before it is even more effective, Widely stagnate, as a drug for blocking ACE. I lower the grip, however, and a number of contraindications. side effects, For example, a cough.

Newsgroups about Enalapril Hexal on the forums may be generally positive as well. As a result, I effectively reduce the arterial vice, it is inexpensive, however, it is often a bit less expensive.

Price Enalaprilu, de buy

Lykarskiy zasib for sale of hacking.

Skіlki kostu Enalapril 10 mg? Close to 15 rubles.

The price of Enalapril Hexal will be 85 rubles per pack of 20 pieces of 20 mg each.

• Online pharmacies of Russia Russia
• Online pharmacies of Ukraine Ukraine
• Online pharmacies Kazakhstan Kazakhstan

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PaniApteka

BIOSPHERE

Osvita: Graduated from Bashkir State Medical University for the specialty "Likuvalna on the Right". In 2011, she got a diploma and a certificate in Therapy. In 2012, she got 2 certificates and diplomas for "Functional Diagnostics" and "Cardiology". In 2013, roci completed a course on "Actual nutrition of otorhinolaryngology in therapy." In 2014, the course passed the course of advising qualifications for the faculty "Clinical echocardiography" and the course for the specialty "Medical rehabilitation".

Dosvid robots: From 2011 to 2014 he was pratsyuvala therapist and cardiologist in the MBUZ Poliklinika №33 m Ufa. 2014 Roku Pratsyu Cardiologist і Lіkar functional diagnostics in MBUZ Poliklinika №33 m Ufa.

when zasosuvanny enalaprilu appeared allergic cough. Dovgo could not be aware of anyone. I thought it was a mess with the lungs. She straightened herself out - lightly in order. And the cough was just vimotuvali me. Buv attacks, went into a cough so that it brought vibigati from the huge mіsts, schob not lyakati, in direct sense, people. Fortunately, she instructed me, if a relative came to visit, as if she told me, as she did it in the know, that they passed through the price, if they took enalapril. Cough coughing up, if I switched to the other drug

A vidminny drug for the normalization of arterial vise. I have a granny without a yak, a yak without arms.

Pohudet.Org: When the burners are filled with something, there will be a drop of alcohol in them, and it will go down a lot.

Volodymyr: Especially the pills are added to me, it’s very important for me to sleep in a dream, ale like a satan’s son.

Lera: I went overboard in vlasnoy dosvіdі: Іngavirіn pratsyu.

Diana: Good for Niko. When stuck, I can get rid of AQUAMISTER, apparently.

All materials presented on the site must have a pre-existing and knowledgeable character and cannot be considered a drug by the method of treatment or sufficient advice.

Enalapril

structural formula

Russian name

Latin name of speech Enalapril

cheery name

(S) -1 - L-alanyl] -L-proline (in viglyad maleate)

Gross formula

Pharmacological group of speech Enalapril

Nosological classification (ICD-10)

CAS code

Characteristics of speech Enalapril

Ingibitor APF, which is carried to the LZ, which is poured into the RAAS. Let's take amino acids L-alanine and L-proline.

pharmacology

Hypertensive hypertension, stagnant for the treatment of acute hypertension (primary arterial hypertension of any degree of severity) and renovascular hypertension such as in monotherapy, such as those associated with combined hypertension Enalapril also stays in order to get rid of, or to increase the development of heart failure.

When I am accepted in the middle of the enalapril, I’ll get wet and go to enalaprilat, which is a highly specific and preferential ACE engineer, but do not disguise sulfhydryl groups.

ACE (peptidyl dipeptidase A) catalyzes the conversion of angiotensin I into vasopressor peptide angiotensin II. To reduce the concentration of angiotensin II in the blood plasma to reduce the concentration of angiotensin II in the blood plasma, which is more difficult for the decrease in the activity of the blood plasma renin (as a result of the decrease in the negative nocturnal ring at the onset of alleviation) At the same time, SAT and DAT, OPSS decrease, post-and anterior vantage on the myocardium.

Enalapril widened the wider world of arteries, lower veins, at which the reflexive increase in heart rate is not meant.

ACE is identical to the enzyme kinase II, so enalapril can also block the rupture of bradikinin, a peptide that volodin circulates vasodilating dyu. The value of the effect in therapeutic child enalaprilu vimagaє clarification. The main mechanism of the antihypertensive action of enalapril is the suppression of the activity of the RAAS; Antihypertensive effect of greater bends with high concentration of renin, lower with normal or lower.

The stagnation of enalapril by patients with arterial hypertension should be brought to a decrease in the arterial vise as in the position of standing, so in the position of lying without a significant increase in heart rate. Symptomatic orthostatic (postural) hypotension when using enalapril grows rarely.

Effectively, the ACE activity will develop in 2-4 years after taking a single dose of enalapril in the middle. The antihypertensive action takes 1 year to develop, the maximum reduction of the arterial grip is spontaneous after 4-6 years after receiving enalapril. The triviality of the diya is to lie down in the dozi. When the recommended doses are consumed, antihypertensive action and hemodynamic effects are taken for 24 years after receiving.

For children, the optimal reduction of the arterial grip can be achieved in a number of ways. The retreat of therapy with enalapril is not a severe arterial vise.

Hypotensive therapy with enalapril leads to significant regression of hypertrophy of the louse and preservation of its systolic function.

In patients with an underlying hypertension, a decrease in the arterial clutch is supervised by a decrease in the OPSS and an increase in the heart wikid, with a high heart rate not to change or to change insignificantly.

When taken with enalapril, it stimulates the reduction of blood flow. With a large GFR, there is no change, but there are no signs of catching sodium or ridini. However, in the case of children with a decrease in glomerular filtration rate, the speed of the ear is getting better.

Enalapril changed the internal glomerular hypertension, with the development of glomerulosclerosis and the development of chronic nircum deficiency.

Trivale storing enalaprilu at patients with hypertension and nirk deficiency you can bring up to the full function of the number, so that it can be confirmed by the SCF.

Patients with a nircum deficiency and a blood-borne diabetes, for example, without a new stimulus, have a decrease in albumen, in the presence of IgG nirkas, as well as a decrease in the amount of blood glucose in the case of receiving enalapril.

With a one-hour intake of enalapril and thiazide diuretics, the antihypertensive effect is more likely to develop. Enalapril changes in order to increase the development of hypocalypse, viclikanoy with thiazidine diuretics.

Therapy with enalapril is not tied to a neat infusion on the concentration of sech acid in blood plasma.

Therapy with enalapril supravoduzhuetsya friendly way on the alleviation of lipoprotein fractions in the blood plasma and in the daytime in flux, or in a friendly way on the concentration of zahal cholesterol.

In patients with CHF on aphid therapy with heart glucosides and diuretics with enalapril, there is a decrease in OPSS and AT. The heart-shaped wikid is going down, at that hour the heart rate will go down. The grip of the wedge in the legendary capillaries also decreases. tolerance up to physically assigned and the degree of seriousness of heart failure, assessed according to the criteria of NYHA, to grow. Dani efekti is spared during trivial therapy with enalapril.

In patients with mild and moderate degrees of severity of heart deficiency, he was confident in the progress of dilatation of heart and heart deficiency, so that they could stand up to the decline of a small-scale and systolic disease.

In case of dysfunction of the livochka, enalapril reduces the development of the main ischemic diseases (including the frequency of development of myocardial infarction and the number of hospitalizations due to the drive of unstable angina pectoris).

Enalapril reduced the frequency of sleepy arrhythmias in patients with heart failure, if the main mechanisms and key values ​​of the given effect are not visible.

With CHF, a clunky clinical effect is more likely to occur with a trivial treatment lasting 6 months or more.

Vsmoctuvannya. When I get it in the middle of the enalapril, it gets wet in the intestinal tract. C max enalapril in syrovattsi blood is reached for 1 year after being received in the middle. The step of wetness when taking in the middle becomes approximately 60%. One-hour reception of їzhі doesn’t pour on the soaked enalaprilu.

When enalapril is moistened, it is quickly hydrolyzed due to the statements of the active metabolite of enalaprilat - a strong inhibitor of ACE. C max of enalaprilat in syrovatz blood should be observed in about 4 years after taking a dose of enalapril in the middle. The triviality of moisture and hydrolysis of enalapril is appropriate for the recommended recommended therapeutic doses. Healthy volunteers have normal function nirok C ss enalaprilat in syrovattsi blood can reach up to 4 days per ear taken enalapril.

Rozpodil. In the range of therapeutic doses, enalaprilat in blood plasma does not overtake 60%.

Enalaprilate easily penetrates through the histological barriers, including the hematoencephalic bar, a small amount penetrates through the HPB and into breast milk.

Metabolism. There is no tribute about the most significant paths to the metabolism of enalapril, including hydrolysis to enalaprilat. The rate of hydrolysis of enalapril can be reduced in patients with damaged liver function without reducing the therapeutic effect.

Vivedennya. Vivennya enalaprilat to be healthy - 60% (20% - in an uncontrolled viglyad and 40% - in a viglyad enalaprilat), through the intestines - 33% (6% - in an invincible viglyad and 27% - in a viglyad enalaprilat). The main metabolites, which start in the section, are enalaprilat, which become approximately 40% of the dose taken, and enalapril does not change. Danikh about іnshі metabolites of enalaprilu is not. The concentration profile of enalaprilat in blood plasma triggers the endov phase, which is evidently explained by the effects of ACE. T 1/2 enalaprilat is nearly 11 years old.

Special groups of patients

Damage to the function of nirok. AUC enalapril and enalaprilat improve in patients with nirk deficiency.

Patients with mild and moderate degrees of normal deficiency (Cl creatinine 40-60 ml / day) receive enalapril taken in a dose of 5 mg 1 time for an equally important AUC value of enalaprilat approximately 2 times in the digestive tract, low in patients.

In patients with severe nirk deficiency (Cl creatinine ≤30 ml / hour), for bagatoraz suction of enalapril, the AUC value of enalaprilat increases by about 8 times, T 1/2 is increased by C.

Enalaprilat can be used for intravenous administration from the bloodstream behind the additional procedure of hemodialysis. Clearance during hemodialysis becomes 62 ml / hv (1.03 ml / s).

Breast year bath. For a one-time intake of enalapril in a dose of 20 mg in patients in the psychoactive period, the middle C max of enalapril in breast milk to become 1.7 μg / l (0.54-5.9 μg / l) after 4-6 years of delivery. The average C max of enalaprilat becomes 1.7 mcg / l (1.2-2.3 mcg / l) and is promoted in the early hour for 24 years after receiving. With the urahuvannya of the tributes about the maximum concentration in breast milk, the maximum survival rate of enalapril by the baby breastfeeding, Become 0.16% of the dosage, rozrahovanoi with urahuvannyam masti tila materi.

When received enalapril vseredin in a dose of 10 mg 1 time for an extra stretch of 11 ms, C max for enalapril in breast milk to become 2 μg / l after 4 years, and when received, enalaprilat - 0.75 μg / l after about 9 years after receiving. The average concentration in breast milk for 24 years after receiving enalapril becomes 1.44 mcg / l and enalaprilat - 0.63 mcg / l.

Gagging Enalapril's speech

Essential hypertension of any degree of gravity; renovascular hypertension; heart lack of any degree of severity (in patients with classy manifestations of heart failure), there were also indications for the improvement of the vision of patients, the hope for the progress of the state of seizure of the frequency, prevention of development of clinically circulated heart failure (in patients without key symptoms heart failure due to the dysfunction of the lingering slut enalapril indications for the development key manifestations sickness, lowering the frequency of hospitalization for the drive of heart failure); prophylaxis of coronary ischemia in patients with dysfunctional lingual dysfunction for reducing the frequency and development of myocardial infarction, reducing the frequency of hospitalization for the drive of unstable angina.

Prototype

Sensitivity has been adjusted to enalaprilu or other ACE ingibitors; angioedema in the anamnesis, dressings with anterior angiotensive fever, as well as depression abo idiopathic angioedema; one hour stasis with aliskiren or aliskiren-containing LZ in patients with diabetic diabetics and / or impaired function of nirok (GFR<60 мл/мин/1,73 м 2) (см. «Взаимодействие»); возраст до 18 лет (безопасность и эффективность применения не изучены); беременность и период грудного вскармливания; наследственная непереносимость лактозы, дефицит лактазы, синдром глюкозо-галактозной мальабсорбции.

Crimped to sucking

Bilateral stenosis of the nirkovy arteries or stenosis of the artery of the single nirka; mill for transplantation of nirka; aortic or mitral stenosis (with impaired hemodynamic indicators); hypertrophic obstructive cardiac disease; IXC; cerebrovascular disease (including lack of cerebral blood circulation); nirkova deficiency (Cl creatine<80 мл/мин); угнетение костномозгового кроветворения; системные заболевания соединительной ткани (в т.ч. склеродермия, системная красная волчанка), иммуносупрессивная терапия, лечение с применением аллопуринола или прокаинамида или комбинация указанных осложняющих факторов; печеночная недостаточность; сахарный диабет; гиперкалиемия; одновременное применение калийсберегающих диуретиков, препаратов калия, калийсодержащих заменителей поваренной соли и препаратов лития; проведение процедуры афереза ЛПНП с использованием декстрана сульфата; отягощенный аллергологический анамнез или ангионевротический отек в анамнезе; состояния, сопровождающиеся снижением ОЦК (в т.ч. при терапии диуретиками, соблюдении диеты с ограничением поваренной соли, диализе, диарее или рвоте); проведение десенсибилизации аллергеном из яда перепончатокрылых; у пациентов, находящихся на диализе с применением высокопроточных мембран (таких как AN 69 ®); после больших хирургических вмешательств или при проведении общей анестезии; у пациентов негроидной расы; пожилой возраст (>65 rockiv); primary aldosteronism.

Stagnation during vaginosis and breastfeeding

When the vaginosity is established, enalapril is guilty of innocently accusations, as only life is not necessary for the mother.

Epidemiological data show that there is a teratogenic effect on the ACE in the first trimester of vaginosity. While the therapy with an ACE with an ACE is not necessary for life, then women who are planning to have a stay, then they are allowed to have a hypotensive drug that is not tolerated.

Angіbіtori ACE can become sick or the beating of a fetus or a newly born fetus in case of stasis in the II and III trimesters of vaginosity. Stagnation of ACE ings in the period of supernatant with a negative influx on the fetus and the newborn, including the development of hypotensiveness, low deficiency, hypercalypse and / or hypoplasia of the neonatal disease. Also, I have seen about prematurity, intrauterine development of the fetus and non-closure of the arterial (Botallov) duct, it is not clear, there are some problems associated with the development of the APF. In quiet people, if an hour is needed for an ACE’s Ingibitor for an hour, it’s necessary to have a periodical ultrasound scan for an assessment of the index of an amnotic birth - when the need arises when an oligogram doesn’t need it Protest, і patient, і lіkar guilty of the nobility, that olіgogіdramnіon develops with a non-vortex fetus. As soon as the ACE ingibitories become stagnant for an hour of vaginosity and the development of oligogramnos is slowed down, then in the absence of the term of vagineness for assessing the functional stan of the fetus, it may be necessary to carry out a test without the need for professional testing.

It is possible, the development of oligog_dramnion will be brought to fruition. The process of acceleration can lead to contracture of the cranial bones, deformation of the cranial cysts, including the facial part, hypoplasia of the legends. When enalapril is consumed, it is necessary to inform the patient of a clearly potent risk for the fetus. The new women, whose mothers took enalapril, were responsible for the retardation of arterial hypotheses, oliguria and hypercalculations.

Enalapril, which penetrates through the placenta, may have frequent visions from the blood circulation of the newborn due to the additional peritoneal dialysis; theoretically, there can be visions for the help of an exchange of blood transfusions.

Enalapril and enalaprilat are seen in breast milk in small concentrations. If necessary, the intake of enalapril in the period of lactation, breastfeeding should be tightened.

Pobichni diya speeches Enalapril

The frequency of the manifestation of unwelcoming side reactions is directed as before the classification of the WHO: even more often (> 1/10); often (> 1/100,<1/10); нечасто (>1/1000, <1/100); редко (>1/10000, <1/1000); очень редко (<1/10000, включая отдельные сообщения); частота неизвестна (определить частоту возникновения по имеющимся данным невозможно).

On the side of the blood and lymphatic system: infrequently - anemia (including aplastic and hemolytic); Ridko - neutropenia, decrease in hemoglobin and hematocrit, thrombocytopenia, agranulocytosis, reduction of cystic carcinoma, pancytopenia, lymphadenopathy, autoimmune seizure.

On the side I will change the words and the damaged food: infrequently - gіpoglіkemiya (div. "Zasterezhennya").

On the side of the central nervous system: even more often - zapamorochennya; often - headache, depression; infrequently - confusion of symptoms, drowsiness, lack of sleep, increased sleepiness, paresthesia, vertigo; Ridko - unwitting dream, ruined sleep.

On the side of the organs in hearing and labyrinthine damage: infrequently - noise from wuhah.

On the side of the organ zoru: Ridko - unclearness of the zoru.

On the side of the heart-vascular system: often - a decrease in the arterial grip, obscurity, beating in the breasts, broken heart rhythm, angina pectoris, tachycardia; infrequently - orthostatic hypotension, seeing heart disease, myocardial infarction or insult (it is possible to reason with the sharp decrease in the arterial grip in the patients of the group of high risk) (div. "Alert"); Ridko - Raynaud's syndrome.

On the side of the mental system, organs of the breast and middle: even more often - cough; often bad luck; infrequently - rhinorrhea, sore throat, hoarseness, bronchospasm / bronchial asthma; Ridko - legenevіinfіltrati, rhinitis, allergic alveolitis / eosinophilic pneumonia.

On the side of the herbal system: even more often - nudota; often - diarrhea, pain in the abdomen, loss of relish; infrequently - intestinal laxity, pancreatitis, bloating, dyspepsia, constipation, anorexia, teasing of the slunker, dryness of the mucous membrane of the empty mouth, twisting of the slurry and two digits of the intestine; Ridko - stomatitis / aphthous infections, glosses; even more rarely - an intestinal quagmire.

On the side of the stove and the youngsters: Ridko - pechinkova lack, hepatitis (hepatocellular or cholestatic), including hepatic necrosis, cholestasis (including zhovtyanitsyu).

On the side of shkіri and іdshkіrnyh fabrics: often - reactions of hypersensitivity / angio-neurotic swelling of the face, lips, tongue, vocal folds і / abo larynx, shkіrni visipannya; infrequently - increase in the appearance, sverbіzh shkіri, kropivyanka, alopecia; Ridko - multiforme erythema, Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis, pemphigus, erythroderma.

When there was a development of a symptom complex, which can be superficially susceptible to symptoms and / or all of the symptoms: fever, serositis, vasculitis, malgia / myositis, arthralgia / arthritis, a positive test for antinucleopharyngeal antibodies It can also be used for sensitization, photosensitivity, or even sensitization.

On the side of nirok and secular nobles: infrequently - impaired function of nirok, nirkova lack, proteinuria; Ridko - oliguria.

On the side of the endocrine system: the frequency of miscarriage is a syndrome of inadequate secretion of ADH.

On the side of the body organs and thoracic areas: infrequently - erectile dysfunction; Ridko - gynecomastia.

Inspection of given laboratory and instrumental dosages: often - hypercalcium, an increase in the concentration of creatine in the blood; infrequently - giponatrієmіya, increasing the concentration of sečovina in the blood; Ridko - an increase in the activity of liver transaminases, an increase in the concentration of bilirubin in the blood.

Zagalny rozladi: even more often - asthenia; often - pidvischena stomatomy; infrequently - m'yazovi sudomi, heat up the blood to the shkiri of exposure, in the face of discomfort, feverish woman.

In small cases with an one-hour intake of ingibitoriv ACE (including enalapril) and intravenous preparations of gold (sodium aurothymalate), descriptions of a symptom complex, including a history of symptoms, arthritis, arthritis

Undesirable occurrences that were detected during the post-marketing period for enalaprilu (a causal link of non-establishment):іnfektsіya sechovivіdnih shlyahіv, іnfektsії verhnіh dihalnih shlyahіv, bronhіt, zupinka sericite, fіbrilyatsіya peredserd, operіzuyuchy herpes, melena, ataksіya, tromboembolіya gіlok legenevoї arterії that іnfarkt lung gemolіtichna anemіya, vklyuchayuchi vipadki gemolіzu in patsієntіv defіtsitom of glucose-6-fosfatdegіdrogenazi.

vzaєmodiya

Інші hypotensive patients. With a one-hour consumption of enalapril, an additive effect can be prevented.

In case of stagnation of enalapril, one hour with other hypotensive diseases, especially with diuretics, it is possible to promote the strengthening of the antihypertensive effect.

Immediately zasosuvannya with beta-adrenergic blockers, methyldopia or CCB increases the rate of antihypertensive effect.

Immediately, the intake of alpha-, beta-blockers and ganglionic blockers is guiltyly carried out under a retinal lykarsky control.

Immediately zasosuvannya with nitroglycerin, other nitrates or vasodilators for antihypertensive effect.

Kaliy sirovatki blood. In patients with arterial hypertension, who took enalapril in monotherapy for more than 48 years, the increase in calories in syrovatz blood in the middle by 0.2 mmol / l was increased.

With a one-hour consumption of enalapril with diuretics, it is possible to inject into the intake of ionic calories (thiazidny or loop diuretics), hypocalmus, due to the presence of diuretics, as a rule, to relieve the symptoms.

Risk factors for the development of hypercalcium є nirkov deficiency, diabetic diabetics, instantaneous congestion of high blood sugar diuretics (for example, spironolactone, eplerenone, triamterene and amilorides), as well as calories The stagnation of high-calorie additives, high-calorie diuretics, or high-calorie salts, especially in patients with impaired functions, can lead to a significant increase in the amount of calories in the blood. If there is a need for an one-hour consumption of calories, they may be taken in place of a large amount of drugs in the process of taking care and regularly monitoring the calories in the blood.

Hypoglikemichnizasobi. One hour of stopping of ingibitorіv ACE and hypoglycemic diseases (insulin, hypoglycemic drugs for a patient in the middle) can make the hypoglycemic effect of a hypoglycemic effect. Denmark's effect, as a rule, is most often promoted by the first type of combined therapy, as well as among patients with impaired function. Patients with diabetic diabetics, who take hypoglycemic drugs for taking in the blood, or insulin, then regularly monitor the glucose concentration in the blood, especially by stretching the first month of one-hour hypotension.

Preparations for lithium. For example, injecting sodium into the bloodstream, the blood pressure of the APF can reduce the amount of time it takes to monitor the blood pressure, and with the one-hour stagnation of drugs in the blood and blood pressure the blood pressure is regularly monitored.

Tricyclic antidepressants / antipsychotics / for anesthesia. Suddenly the loss of anesthetic drugs, tricyclic antidepressants and antipsychotics with ACE inhibitors can lead to a further decrease in arterial pressure (div. "Guard").

Ethanol. Ethanol by virtue of the antihypertensive effect of the ingibitoriv ACE.

Acetylsalicylic acid, thrombolytics and beta-blockers. Enalapril can be consumed at once with acetylsalicylic acid (antiplatelet agent), thrombolytics and beta-blockers.

Sympathomimetics. Sympathomimetics can reduce the antihypertensive effect of ACE inhibitors.

Refinery. Refinery, including Selective Ingibitori COG-2, can reduce the effect of diuretics and other hypotensive conditions. In addition, the antihypertensive effect of ARA II or angibitoris ACE can be weakened by a one-hour consumption from a refinery, incl. with selective ingibitors COX-2.

For children with impaired functionality (for example, for children who are sick with illnesses, including those who are sick with diuretics), they will accept the therapy of refineries, in particular for those who are sick. You can go further to the destruction of the function of nirok, including the development of a hostile nirkova disadvantage. Dana efekty beckon to the werewolves, for that overnight storing of danny of lykarskhis guilty is carried out with the safety of the children with a broken function of nirok.

Subv_yna blockade of RAAS. Subsidiary of the blockade of RAAS due to the stagnation of ARA II, the ingibitoriv of the APF and the lack of monotherapy in the function of monotherapy (ingibitor renin) is associated with the development of arterial hypotensiveness, intractability, hypothermia. Necessary regular monitoring of arterial grip, function of nirok and instead of electrolytes in the blood of patients, who take enalapril and іnshі LZ at once, which is poured into the RAAS. Enalapril is not guilty of stagnation at once with aliskiren or aliskiren-containing LZ in patients with diabetic diabetics and / or for impaired function of nirok (GFR<60 мл/мин/1,73 м 2).

Immediate stasis of ingibitoriv ACE with ARA II in patients with diabetic nephropathy is suggested.

Gold preparations. In small cases with a one-hour intake of gold preparations for parenteral administration (sodium aurothiomalat) and ingibitoriv ACE, including enalapril, a

Іngіbіtory mTOR. Patients who are stagnant have one hour for an ACE Ingibitor and an Enzyme Ingibitor mTOR (mammalian target of rapamycin- the target of rapamy in the clines of ssavts) (for example, temsirolimus, sirolimus, everolimus), therapy can be supervised by the development of angioeurotic embryo.

Alopurinol, cytostatics and immunodepressants. One hour, the storage with ACE ingibitors can promote the development of leukopenia.

Cyclosporine. One hour, the reception with the ACE Ingibitors can advance the development of hypercalculation.

Antacid. You can change the accessibility of the ACE ingibitors.

Teofilin. Enalapril will relax the LZ, so take revenge on theophilin.

Іnshі lіkarskі zasobi. Do not sposter the clinically significant pharmacokinetic drug interaction between enalapril and the onset of drugs: hydrochlorothiazide, furosemide, digoxin, timolol, methyldopa, cyclone, culindometacin,. With a one-hour consumption of enalapril and propranolol, the concentration of enalaprilat in the blood decreases, and the effect is not clinically significant.

Overdose

symptoms: loss of arterial pressure (to be repaired after about 6 years), up to the development of collapse, myocardial infarction, severe damage to cerebral blood circulation or thromboembolic acceleration, loss of water-electrolyte balance zapamorochennya, unconsciousness, seeing fear, sudomi, cough, stupor. The concentration of enalaprilat in the blood plasma is 100-200 times per day, without the consumption of therapeutic doses, and the concentration of enalapril in the blood plasma is reduced to 300 and 440 mg of enalapril.

lykuvannya: transfer the patient to a horizontal position on a low pillow. In light vapors, the slurry is shown in the middle of the active vug, in the larger ones - come in, direct to the normalization of the arterial clutch (i / v introduction of 0.9% sodium chloride, plasma substitutes, if necessary vivedennya enalaprilatu - 62 ml / hv). Patients with bradycardia, stiff before therapy, are shown setting the rhythm.

introduction

Zapobіzhni come in speeches Enalapril

Arterial hypertension is symptomatic. Symptomatic arterial hypertension rarely occurs in patients with persistent arterial hypertension. In patsієntіv of arterіalnoyu gіpertenzієyu, SSMSC priymayut enalapril, arterіalna gіpotenzіya rozvivaєtsya chastіshe on tlі znevodnennya scho vinikaє, napriklad in rezultatі terapії dіuretikami, obmezhennya spozhivannya kuhonnoї solі have patsієntіv, SSMSC perebuvayut on dіalіzі and takozh in patsієntіv of dіareєyu abo blyuvannyam ( div. "pobichni dei", "Vzaєmodiya"). Symptomatic arterial hypertension is susceptible to occurring in patients with heart failure, for example, without a lack of heart disease.

Arterial hypertension develops more often in patients with a more severe degree of heart failure due to hyponathic or impaired function of those who stagnate more high doses of loop diuretics. In the case of these patients, enalapril was later repaired by a visual doctor, who is guilty of being especially responsible for changing the dose of enalapril and / or a diuretic. An analogous rank of following patients with ischemic ailments of the heart or cerebrovascular ailments, in those who have an overly reduced arterial grip can lead to the development of myocardial infarction or insult.

When developing an arterial hypotension of a patient next to the area and, if necessary, introduce 0.9% sodium chloride solution. Transient arterial hypotension in case of enalapril intake is not contraindicated until a further increase in the dose and increase in dosage, therapy can be continued in order to keep the background and normalization of arteriality.

In children with heart deficiency and normal or normal decrease in AT enalapril, the decrease in arterial grip can be reduced. A reaction was given to the reception of enalapril ochіkuvan і not є beforehand for the appointment of a lіkuvannya. In quiet patients, if the arterial hypotension is stable in nature, then the dose should be reduced and / or given a diuretic or enalapril.

Aortic or mitral stenosis / hypertrophic obstructive cardiomyopathy. Yak and all LZ, which volodyut as a vasodilating agent, the ACE Ingibitories are guilty of protecting the children from the obstruction of the road to the current from the lynch.

Damage to the function of nirok. Children have arterial hypotensiveness, which develops after a cob of treatment by the ACE's ingibitors, which can lead to a further degradation of the function of nirok. Have some vipadkah about the development of hostile nirkova disadvantages, zvvychay circulating character.

Patients with a nircovy deficiency may have a lower dose of that / or the frequency of enalapril taken. In children with bilateral stenosis of the nirkovy arteries or stenosis of the artery of the single nyrkas, the increase in the concentration of serovine in the blood and creatine in the syrovatous blood was observed. The snakes were of a werewolf character, and the indicators turned to cob values ​​when they were pinned down. The Danish character is the best among the children with a nirk deficiency.

In children, who were not too sick to get sick, enalapril, in addition to diuretics, caused a slight increase in the concentration of blood and creatine in the blood. In such cases, there may be a decrease in the dose and / or the dose of diuretics and / or enalapril.

Nirka transplantation. Likuvannya enalapril is not recommended for patients undergoing transplantation of nirka through the daytime of such a trip.

Pechinkova lack. Stagnation of ACE ingibitors is rarely associated with a developmental syndrome, which can be repaired from cholestatic disease or hepatitis, progressive to fulminant liver necrosis, and sometimes with a fatal result. Mechanism of the given syndrome of non-implantation. When there is a sign, or with a significant increase in the activity of hepatic transaminases on the presence of an ACE reaction, it is seen as a result of enalapril and the indication of some additional therapy; the patient is guilty of perebuvati pіdpovіdnim visibility.

Neutropenia / agranulocytosis. Neutropenia / agranulocytosis, thrombocytopenia and anemia are more likely to develop in patients who receive angiotensin-converting enzyme (ACE) inhibitors. Neutropenia in patients with normal functioning of neuropsychiatric disorders and without those accelerating factors is rare.

Enalapril slіd zastosovuvati of oberezhnіstyu Especially in patsієntіv of systemic zahvoryuvannyami spoluchnoї tkanini (System Chervoniy vovchak, sklerodermіya that іn.) SSMSC take іmunosupresivnu terapіyu, allopurinol prokaїnamіd abo, abo kombіnatsієyu zaznachenih uskladnyuyut faktorіv, Especially Je Yakscho vzhe іsnuyuchі funktsії nirok torn down. Serious infectious diseases develop in children from cich patients, as in a number of patients they do not refer to intensive therapy with antibiotics. Even if such patients are stuck in enalapril, it is recommended to carry out regular monitoring of the number of leukocytes and lymphocytes in the blood and patients in advance of the need to be aware of any problems.

Hypersensitivity reactions / angioedema. In case of stagnation of angiotensin ACE, including enalapril, there were one incidence of angioedema, signs, lips, tongue, vocal folds and / or larynx, which occurred in the course of larynx. In a couple of cases, there are mossy growths of the intestinal swelling. In such cases, it was inaccurately pinned with enalapril and reliably helped to support the patient's body with the help of control and correction of clinical symptoms. To navigate in quiet droplets, if you are afraid only to get sick without developing respiratory distress syndrome, patients may be aware of the triviality of caution, some of the therapy with antihistamines and corticosteroids may be.

Even more rarely I saw about the lethal end through an angioeurotic dressing tied with a larynx or tongue. A lump of language, vocal folds, or the larynx, can lead to obstruction of the dysfunctional nobles, especially in patients who have undergone surgery on the organs of the dysfunction. In quiet cases, if the swelling is localized in the language, the vocal folds or the larynx and the obstruction of the larynx can occur, then it is inaccurately indicative of the appearance of the disease, if it is possible to include 0.3-0.5 ml ) і / or to prevent the passage of the wicked nobles.

In children of the negro race, who take the Angibitories of the APF, the angioeurotic nagging is more frequent than in the children of the young races.

Patients, who have an anamnesis of angioedema, not being tied with an ACE angioedema, may be in a larger world, up to the risk of developing an anioneurotic malignancy on the background of therapies with an angiotensin

Anaphylactic reactions for an hour when the desensitization of an allergen is carried out with the help of a retraction of frequent crises. In children who are sick, children who take the ACE Ingibitories develop quite a lot of anaphylactic reactions for an hour after the desensitization of the allergen is often removed. Undesirable reactions can be unique, even before the ear is carried out desensitization of the hour, pin down the reception of the ACE ingibitor.

Anaphylactoid reactions for the hour of LPNShch-aheresis. Patients who take APF ingibitories after an hour of LPNSh-aphèresis with dextrasulfate vikorystannym, are often encouraged to be safe for the life of an anaphylactic reaction. The development of these reactions can be unique, as it is time to skasuvati ingibitor ACE before the cob of skin procedure LPNShch-apheresis.

Hemodialis. Anaphylactic reactions are promoted in patients who are on the dialysis because of high-flow membranes (such as AN 69 ®) and immediately receive therapy with ACE inhibitors. In the case of given patients, it is necessary to fix the different membranes of the same type, or hypotensive in the same class.

Cough. The diagnosis of cough is promoted in the background of therapy with ACE inhibitors. As a rule, the cough is unproductive, permanent in nature, and coughs up during the course of therapy. Cough, dressing from the stasis of ingibitoriv ACE, is guilty of vrahovuvatis in the differential diagnosis of cough.

Surgical involvement / general anesthesia. Before the hour of the great surgeons, the patient was given an initial anesthesia due to the loss of anesthesia, the antihypertensive effect was observed, the enalaprilat block was approved for angiotensin II, and the patient was diagnosed with compensatory anesthesia. When it comes to developing a turn of the arterial grip, which is explained by a similar mechanism, it is possible to increase the volume of circulating blood.

Giperkaliyєmiya (div. "Vzaєmodiya"). Rizik the development of hypercriticity is promoted in cases of nircovy deficiency, diabetic diabetics, as well as in case of one-hour stagnation of kalyzbergayuchih duretikov (for example, spironolactone, calicherenone, triamteren), and amoleuceric acid added

The stagnation of high-value additives, high-calorie diuretics, or high-value salts, especially in patients with impaired functions, can lead to a significant reduction in the amount of calories in the blood. Hypercalculation can lead to severe, even fatal arrhythmias.

If there is a need for an one-hour consumption of enalapril and re-health of the LZ, care must be taken and regularly monitored for the amount of blood in the blood.

Hypoglikemia. Patsієnti of tsukrovim dіabetom, SSMSC priymayut gіpoglіkemіchnі Message to priya vseredine abo znahodyatsya on іnsulіnoterapії before cob zastosuvannya іngіbіtorіv ACE povinnі Buti proіnformovanі about neobhіdnіst regular monitoring kontsentratsії glucose in krovі (mozhlivіst gіpoglіkemії) Especially protyagom Perche mіsyatsya odnochasnogo zastosuvannya danih lіkarskih zasobіv (div. "Vzaєmodiya").

Subv_yna blockade of RAAS. I have seen about the development of arterial hypotension, lack of tolerance, insult, hyperthermia and deterioration of the function of nirok (including hostile deficiency) in sleepy patients in therapy, especially when they become stagnant. It is not recommended to carry out a sub-blockade of the RAAS in combination with the participation of the ingibitoriv APF from the ARA II or aliskiren.

Prototypically shown at once the consumption of enalaprilu with aliskiren or aliskiren-containing LZ in patients with diabetic diabetics and / or for impaired function of nirok (GFR<60 мл/мин/1,73 м 2) (см. «Противопоказания»).

Lіtnі paciєnti. The efficiency and safety of enalapril is similar in lithuanian and larger young patients with arterial hypertension.

Race. Yak i at zastosuvannі іnshih іngіbіtorіv ACE, enalapril, Mabuchi, Mensch efektivnosti znizhuє arterіalny clutches of patsієntіv negroїdnoї Rasi, nіzh at patsієntіv іnshih races scho Mauger poyasnyuvatisya bіlsh temple poshirenіstyu stanіv of nizkoyu aktivnіstyu renіnu plasma krovі in populyatsії patsієntіv negroїdnoї rasis of arterіalnoyu gіpertenzієyu.

Inflow to the building of keruvati with transport means and mechanisms. When enalapril is stagnant, it is necessary to take care of caring for cars and when busy with potentially dangerous types of activity, so that you need to increase the concentration of respect and speed, psychomotor reactions.

Vzamodії with інshih dіyuchy speeches

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